The coup de théâtre and the enchanting object of performance

Examining three examples from theatre productions in London and Edinburgh between 1997-2001, this article explores the coup de théâtre as a theatrical phenomenon. It argues for the importance of enchantment in conceptualising the coup de théâtre and that the suspension of the rational in relation to such theatrical moments is central to their impact. This sense of enchantment revolves around the changing status of the object in the coup de théâtre, which, it will be suggested, is linked to the shift between animacy and inanimacy. By destabilising rational modes of understanding, the coup de théâtre enters into the temporality of death and mourning, as objects occupy dual ontologies, both living and inanimate, literal and metaphorical. The coup de théâtre, it will be argued, is a point in performance in which perception and memory, the visible and the conceptual, converge, and in which the permanence of death is troubled by the reanimating effect of theatre

White Matter Deterioration May Foreshadow Impairment of Emotional Valence Determination in Early-Stage Dementia of the Alzheimer Type

In Alzheimer Disease (AD), non-verbal skills often remain intact for far longer than verbally mediated processes. Four (1 female, 3 males) participants with early-stage Clinically Diagnosed Dementia of the Alzheimer Type (CDDAT) and eight neurotypicals (NTs; 4 females, 4 males) completed the emotional valence determination test (EVDT) while undergoing BOLD functional magnetic resonance imaging (fMRI). We expected CDDAT participants to perform just as well as NTs on the EVDT, and to display increased activity within the bilateral amygdala and right anterior cingulate cortex (r-ACC). We hypothesized that such activity would reflect an increased reliance on these structures to compensate for on-going neuronal loss in frontoparietal regions due to the disease. We used diffusion tensor imaging (DTI) to determine if white matter (WM) damage had occurred in frontoparietal regions as well. CDDAT participants had similar behavioral performance and no differences were observed in brain activity or connectivity patterns within the amygdalae or r-ACC. Decreased fractional anisotropy (FA) values were noted, however, for the bilateral superior longitudinal fasciculi and posterior cingulate cortex (PCC). We interpret these findings to suggest that emotional valence determination and non-verbal skill sets are largely intact at this stage of the disease, but signs foreshadowing future decline were revealed by possible WM deterioration. Understanding how non-verbal skill sets are altered, while remaining largely intact, offers new insights into how non-verbal communication may be more successfully implemented in the care of AD patients and highlights the potential role of DTI as a presymptomatic biomarker

Lifestyle behaviours of young adult survivors of childhood cancer

This cross-sectional study collected baseline data on the health behaviours of a large population of survivors of childhood cancer in the UK, aged 18–30 years, compared with those of sex- and age-matched controls. Data from 178 young adult survivors of childhood cancer, diagnosed and treated at Bristol Children's Hospital, 184 peers from the survivors' GP practices and 67 siblings were collected by postal questionnaire. Conditional logistic regression analysis showed that, for matched sets of survivors and controls, survivors of a variety of childhood cancers reported lower levels of alcohol consumption (P=0.005), lower levels of cigarette smoking (P=0.027) and lower levels of recreational drug use (P=0.001) than controls. Analysis of matched sets of survivors and siblings showed similar trends but no significant differences. A health behaviour index for each participant was constructed from the data collected on five key health behaviours which influence future health status. Comparison of the means for each case group showed that survivors of childhood cancer were leading healthier lives than controls or siblings. This finding was expressed most clearly as the difference in the means of the health behaviour index for each case group, derived from five health behaviours (one-way ANOVA, P<0.001)

Supporting positive dimensions of health, challenges in mental health care

This paper will explore two contrasting paradigms in mental health care and their relationship to evidence-based practice. The biomedical perspective of pathogenesis and the health perspective of salotogenesis are two major diverse views in mental health care. Positive dimensions of health are traditionally viewed as software not suitable for statistical analysis, while absence of symptoms of disease are regarded as measurable and suitable for statistical analysis and appropriate as a foundation of evidence-based practice. If the main goal of mental health care is to enhance subjectively experienced health among patients, it will not be sufficient to evaluate absence of symptoms of disease as a measure of quality of care. The discussion focuses on the paradox of evidence-based absence of illness and disease versus subjectively experienced health and well-being as criterions of quality of care in mental health care

(Re)acting Medicine: applying theatre in order to develop a whole-systems approach to understanding the healing response.

This is an Accepted Manuscript of an article published by Taylor & Francis Group in Research in Drama Education: The Journal of Applied Theatre and Performance on 30/09/2014, available online: http://www.tandfonline.com/10.1080/13569783.2014.928007UK health and care provision is in crisis. Dominant practices, ideologies and infrastructure need to change. Our research team is investigating how performance-led research and creative practice is able to positively shape that change. Presently biomedicine holds the power; its reductionist research approach and acute medical model dominate. Neither are well-equipped to engage with increasing non-communicable, long-term, multi-issue, chronic ill-health. We believe that creative practitioners should be using their own well-established approaches to trouble this dominant paradigm to both form and inform the future of healing provision and wellbeing creation. Our transdisciplinary team (drama and medicine) is developing a methodology that is rooted in productive difference; an evolving synergy between two cultural and intellectual traditions with significant divergences in their world-view, perceptions, approaches and training methods. This commonality is underpinned by four assumptions that; (1) human-to-human interactions matter, (2) context matters, (3) the whole person and their community matters and (4) interpretation matters. Initially, we are using this methodology to investigate the fundamental human-to-human interaction of a person seeking healing (a healee) with a healer: we believe that this interaction enables the Healing Response - the intrinsic ability of the human organism to self-heal and regain homeostasis. In this paper we reflect on the project’s early stages

Fructan and its relationship to abiotic stress tolerance in plants

Numerous studies have been published that attempted to correlate fructan concentrations with freezing and drought tolerance. Studies investigating the effect of fructan on liposomes indicated that a direct interaction between membranes and fructan was possible. This new area of research began to move fructan and its association with stress beyond mere correlation by confirming that fructan has the capacity to stabilize membranes during drying by inserting at least part of the polysaccharide into the lipid headgroup region of the membrane. This helps prevent leakage when water is removed from the system either during freezing or drought. When plants were transformed with the ability to synthesize fructan, a concomitant increase in drought and/or freezing tolerance was confirmed. These experiments indicate that besides an indirect effect of supplying tissues with hexose sugars, fructan has a direct protective effect that can be demonstrated by both model systems and genetic transformation

Test beam performance measurements for the Phase I upgrade of the CMS pixel detector

A new pixel detector for the CMS experiment was built in order to cope with the instantaneous luminosities anticipated for the Phase I Upgrade of the LHC. The new CMS pixel detector provides four-hit tracking with a reduced material budget as well as new cooling and powering schemes. A new front-end readout chip mitigates buffering and bandwidth limitations, and allows operation at low comparator thresholds. In this paper, comprehensive test beam studies are presented, which have been conducted to verify the design and to quantify the performance of the new detector assemblies in terms of tracking efficiency and spatial resolution. Under optimal conditions, the tracking efficiency is (99.95 ± 0.05) %, while the intrinsic spatial resolutions are (4.80 ± 0.25) μm and (7.99 ± 0.21) μm along the 100 μm and 150 μm pixel pitch, respectively. The findings are compared to a detailed Monte Carlo simulation of the pixel detector and good agreement is found.Peer reviewe