A Modified Cane for the Blind using Computer Vision

 This study aimed to develop “A Modified Cane for the Blind using Computer Vision” that can detect possible objects and obstacles from the surroundings. A collection of a large image dataset to develop a model has been divided into three (3) datasets with the ratio of 70% for training, 20% for validation, and 10% for testing. The model was used for a mobile application to detect objects from the surroundings. A series of designs for a mobile application and a modified cane were created until the final prototype was made. The ultrasonic sensors, micro-controllers, and other electronic components were connected and tested for effectiveness and accuracy. The final prototype of a modified cane and the mobile application were combined to create a system called “a modified cane for the blind using computer vision.” The effectiveness of the system was evaluated by five (5) IT experts and five (5) blind persons in terms of functional suitability, reliability, performance efficiency, usability, security, compatibility, maintainability, portability, and the overall result with a mean of 4.46. The results of the evaluation show that the overall mean was “Excellent.” This implies that the system is effective and meets ISO 25010 standards in terms of software quality

Developing Biotemplated Data Storage: Room Temperature Biomineralization of L1<inf>0</inf> CoPt Magnetic Nanoparticles

L10 cobalt platinum can be used to record data at approximately sixfold higher densities than it is possible to on existing hard disks. Currently, fabricating L10 CoPt requires high temperatures (≈500 °C) and expensive equipment. One ecological alternative is to exploit biomolecules that template nanomaterials at ambient temperatures. Here, it is demonstrated that a dual affinity peptide (DAP) can be used to biotemplate L10 CoPt onto a surface at room temperature from an aqueous solution. One part of the peptide nucleates and controls the growth of CoPt nanoparticles from solution, and the other part binds to SiO2. A native silicon oxide surface is functionalized with a high loading of the DAP using microcontact printing. The DAP biotemplates a monolayer of uniformly sized and shaped nanoparticles when immobilized on the silicon surface. X-ray diffraction shows that the biotemplated nanoparticles have the L10 CoPt crystal structure, and magnetic measurements reveal stable, multiparticle zones of interaction, similar to those seen in perpendicular recording media. This is the first time that the L10 phase of CoPt has been formed without high temperature/vacuum treatment (e.g., annealing or sputtering) and offers a significant advancement toward developing environmentally friendly, biotemplated materials for use in data storage

Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery

Self-folded redox/acid dual-responsive nanocarriers (RAD-NCs) are developed for physiologically triggered delivery of anticancer drug. The evidenced redox/acid responsiveness, facile decoration of ligands, and active tumor-targeting capability of RAD-NCs suggest their potential as a promising formulation for tumor-targeted chemotherapy

A dual wavelength-activatable gold nanorod complex for synergistic cancer treatment

A multifunctional gold nanorod complex was formulated for synergistic anticancer treatment upon ultraviolet (UV) and infrared (IR) light dual irradiations

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

A light-activated hypoxia-responsive conjugated polymer-based nanocarrier is developed for efficiently producing singlet oxygen ((1) O2 ) and inducing hypoxia to promote release of its cargoes in tumor cells, leading to enhanced antitumor efficacy. This dual-responsive nanocarrier provides an innovative design guideline for enhancing traditional photodynamic therapeutic efficacy integrated with a controlled drug-release modality

Balancing act: Motivation, challenges, coping strategies, and academic performance of college student-mothers

This descriptive-correlational study determined the motivation, challenges, coping strategies, and academic performance of college student-mothers. 31 active college student-mothers for the academic year 2020- 2021 responded to the study. A researcher-made questionnaire on motivation and questionnaire on challenges, and an adopted instrument on coping strategies were used. Descriptive statistics employed were mean, rank, and standard deviation, while the inferential statistics used was Spearman Rho Coefficient set at a .05 level of significance. Results revealed that college student-mothers are very motivated to finish their college degree. They were fairly affected by the challenges that they encountered and were predominantly inclined to persist and exert much effort even if faced with very difficult circumstances. Religiosity has been found to be the most prevalent coping strategy used by student-mothers followed by problem-solving in order to overcome their situation. They even exhibit very satisfactory results in their academic performance proving their undeniable academic capability. Moreover, there is no significant relationship between motivation challenges, coping strategies, and academic performance of college student-mothers was considered, motivation. Similarly, academic performance is not a predictor of student mothers' challenges and coping strategies. However, there was a strong correlation and significant relationship between challenges and coping strategies among college student-mothers. The result of the study may provide considerable insight into investigating the motivation, challenges, coping strategies, and academic performance of college student-mothers