Historical analysis of the Brazilian cervical cancer screening program from 2006 to 2013: a time for reflection

BACKGROUND: The Cervical Cancer Database of the Brazilian National Health Service (SISCOLO) contains information regarding all cervical cytological tests and, if properly explored, can be used as a tool for monitoring and managing the cervical cancer screening program. The aim of this study was to perform a historical analysis of the cervical cancer screening program in Brazil from 2006 to 2013. MATERIAL AND METHODS: The data necessary to calculate quality indicators were obtained from the SISCOLO, a Brazilian health system tool. Joinpoint analysis was used to calculate the annual percentage change. RESULTS: We observed important trends showing decreased rates of low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL) and an increased rate of rejected exams from 2009 to 2013. The index of positivity was maintained at levels below those indicated by international standards; very low frequencies of unsatisfactory cases were observed over the study period, which partially contradicts the low rate of positive cases. The number of positive cytological diagnoses was below that expected, considering that developed countries with low frequencies of cervical cancer detect more lesions annually. CONCLUSIONS: The evolution of indicators from 2006 to 2013 suggests that actions must be taken to improve the effectiveness of cervical cancer control in Brazil

Adapting Agriculture to Climate Change: A Synopsis of Coordinated National Crop Wild Relative Seed Collecting Programs across Five Continents

The Adapting Agriculture to Climate Change Project set out to improve the diversity, quantity, and accessibility of germplasm collections of crop wild relatives (CWR). Between 2013 and 2018, partners in 25 countries, heirs to the globetrotting legacy of Nikolai Vavilov, undertook seed collecting expeditions targeting CWR of 28 crops of global significance for agriculture. Here, we describe the implementation of the 25 national collecting programs and present the key results. A total of 4587 unique seed samples from at least 355 CWR taxa were collected, conserved ex situ, safety duplicated in national and international genebanks, and made available through the Multilateral System (MLS) of the International Treaty on Plant Genetic Resources for Food and Agriculture (Plant Treaty). Collections of CWR were made for all 28 targeted crops. Potato and eggplant were the most collected genepools, although the greatest number of primary genepool collections were made for rice. Overall, alfalfa, Bambara groundnut, grass pea and wheat were the genepools for which targets were best achieved. Several of the newly collected samples have already been used in pre-breeding programs to adapt crops to future challenges.info:eu-repo/semantics/publishedVersio

Professores universitários com deficiência: trajetória escolar e conquista profissional

Este estudo tem como foco a educação escolar de pessoas com deficiência. Investigou-se a trajetória escolar de professores universitários, com o objetivo de compreender influências sobre desempenho escolar e identificar razões da distinção que os tornou minoria dentre os milhares de outras pessoas com deficiência que não atingem tal patamar de educação formal e profissionalização. O estudo tem como base teórica os trabalhos de Bourdieu. Optou-se por trabalhar com procedimentos metodológicos de entrevista, questionário e análise de documentos biográficos. Participaram desta pesquisa três professores. O estudo indica que a valorização familiar pelo estudo, a condescendência da instituição escolar e a distribuição do capital cultural objetivado são indicativos do desempenho escolar e profissional destes sujeitos

A Two-Dimensional Oxamate- and Oxalate-Bridged Cu^IIMn^II Motif: Crystal Structure and Magnetic Properties of (Bu₄N)₂[Mn₂{Cu(opba)}₂ox]

A new compound of formula (Bu₄N)₂[Mn₂{Cu­(opba)}₂ox] (<b>1</b>) [Bu₄N⁺ = tetra-<i>n</i>-butylammonium cation, H₄opba = 1,2-phenylenebis­(oxamic acid), and H₂ox = oxalic acid] has been synthesized and magneto-structurally investigated. The reaction of manganese­(II) acetate, [Cu­(opba)]^2–, and ox^2– in dimethyl sulfoxide yielded single crystals of <b>1</b>. The structure of <b>1</b> consists of heterobimetallic oxamato-bridged Cu^IIMn^II chains which are connected through bis-bidentate oxalate coordinated to the manganese­(II) ions to afford anionic heterobimetallic layers of 6³-hcb net topology. The layers are interleaved by <i>n</i>-Bu₄N⁺ counterions. Each copper­(II) ion in <b>1</b> is four-coordinate in a square planar environment defined by two amidate-nitrogen and two carboxylate-oxygen atoms from the two oxamate groups of the obpa ligand. The manganese­(II) ion is six-coordinate in a somewhat distorted octahedral surrounding that is built by two oxalate-oxygen and four carbonyl-oxygen atoms from two [Cu­(opba)]^2– units. The magnetic properties of <b>1</b> in the temperature range 1.9–300 K correspond to those expected for the coexistence of intralayer antiferromagnetic interactions of the type copper­(II)–manganese­(II) across oxamato and manganese­(II)–manganese­(II) through oxalato bridges plus a weak spin canting in the very low temperature domain. Simulation of the magnetic data through quantum Monte Carlo methodology reveals the magnitude of the intralayer magnetic interactions [<i>J</i>_CuMn = −32.5(3) cm^–1, and <i>J</i>_MnMn = −2.7(3) cm^–1], their values being within the range of those previously observed in lower nuclearity systems

Structural versatility driven by the flexible di(4-pyridyl) sulfide ligand: from cobalt(II) single-ion magnets to sheet-like copper(II) weak antiferromagnets

The reaction between the ligand di(4-pyridyl)sulfide (dps) and two salts of divalent first row transition metals (M = Co2+, and Cu2+) resulted in three new compounds with formula: [Co(dps)(4)(H2O)(2)](ClO4)(2)center dot H2O (1), [Cu(dps)(2)(dmso)(2)](n)(ClO4)(2n) (2) and [{Cu(dps)(2)(dmso)(2)}{Cu(dps)(2)(dmso)(H2O)}](n)(ClO4)(4n)center dot 2nH(2)O center dot n(dmso) (3). Crystal structures of 1-3 were determined using single-crystal X-ray diffraction. Crystal structure of 1 consists of a mononuclear complex, in which the dps ligand acts in a monodentate mode through one of the pyridyl nitrogen atoms. Compounds 2 and 3 present the dps ligands bridging metal centers leading to bidimensional coordination polymers. Magnetic properties in the polycrystalline samples of 1-3 in the 300-2 K temperature range were investigated. Complex 1 exhibits a field-induced slow magnetization behavior and behaves as a single-ion magnet with an effective energy barrier for the reversal of magnetization of 22.9 (1.1) K and tau(0) = 5.3(1.2) x 10(-7) s.171203211CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQCOORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MINAS GERAIS - FAPEMIGFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP405199/2016-3; 309687/2018-7; 313068/2017-8Sem informaçãoPPM00508-16; PPM00523-162015/22379-