27 research outputs found

    Ciencias Sociales: EconomĂ­a y Humanidades

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    Este volumen I contiene 29 capĂ­tulos arbitrados que se ocupan de estos asuntos en TĂłpicos Selectos de Ciencias Sociales: EconomĂ­a y Humanidades, elegidos de entre las contribuciones, reunimos algunos investigadores y estudiantes.GĂłmez, presenta un breve examen de la producciĂłn y comercializaciĂłn de rosa en MĂ©xico; Arpi y Portillo realiza un estudio en MĂ©xico sobre el ingreso mĂ­nimo de las familias que identifica la lĂ­nea de pobreza alimentaria en el ĂĄrea rural del sur de MĂ©xico, 2012; Bravo realiza un pequeño estudio donde hablarĂĄ sobre el anĂĄlisis comparado del Sector Gubernamental y la EconomĂ­a Mexicana desde la perspectiva de los eslabonamientos productivos Hirshman-Rasmuss; Caamal, Pat, JerĂłnimo y Romero realizan un estudio sobre los canales de comercializaciĂłn de limĂłn persa en el municipio de MartĂ­nez de la Torre, Veracruz; MacĂ­as y Perales nos hablarĂĄn sobre una anĂĄlisis del comercio estratĂ©gico en el TLCAN: El Estado en la polĂ­tica agrĂ­cola de biocombustibles; Figueroa, PĂ©rez y GodĂ­nez se expresan acerca de la importancia de la comercializaciĂłn del cafĂ© en MĂ©xico; SepĂșlveda, SepĂșlveda y PĂ©rez realizan un diagnĂłstico, retos del comercio electrĂłnico en el Sector Agroindustrial Mexicano; Duana mediante su trabajo nos muestra y habla sobre la inversiĂłn extranjera directa y su impacto en crecimiento de MĂ©xico, un anĂĄlisis en prospectiva: 1999-2010; Figueroa, PĂ©rez y RamĂ­rez hacen un estudio acerca sobre la importancia de la Banca en MĂ©xico; PĂ©rez, Figueroa, GodĂ­nez y PĂ©rez presenta un trabajo acerca de la competitividad de la producciĂłn agrĂ­cola en MĂ©xico, un anĂĄlisis regional; RodrĂ­guez, Espinosa y MĂĄrquez analizan todo acerca de el SIAL productor de quesos en Poxtla, competividad y territorio; Garza nos habla acerca de la intermediaciĂłn financiera al servicio de la comunidad indĂ­gena: el fondo regional indĂ­gena Tarhiata Keri; Arroyo, Aguilar, Santoyo y Muñoz realizan un estudio acerca de la demanda de Importaciones de durazno (Prunus pĂ©rsica L. Batsch) en MĂ©xico procedentes de Estados Unidos de AmĂ©rica (1982-2011); Loera y SepĂșlveda analizan los parĂĄmetros de la productividad forestal en la producciĂłn de madera en rollo; PĂ©rez, Morett y Tecpan realizan un anĂĄlisis de factores sociales, ambientales y econĂłmicos del territorio rural cercano a la ciudad de MĂ©xico; GodĂ­nez, Figueroa y PĂ©rez realizan un estudio acerca de la crisis econĂłmica mundial y su efecto sobre los flujos migratorios de AmĂ©rica Latina; MagadĂĄn, HernĂĄndez y Escalona presentan la tipologĂ­a de los sujetos sociales que intervienen en el mercado campesino de OcotlĂĄn Oaxaca; Tavera y Cobos nos hablan de la normalizaciĂłn del proceso de compostaje: una opciĂłn para desarrollar el mercado de la composta; Piña y PĂ©rez hablan acerca de la reestructuraciĂłn del capitalismo y crisis polĂ­tica en MĂ©xico; GonzĂĄles, Rucoba y RamĂ­rez realizan un estudio de la rentabilidad de la producciĂłn de miel en el municipio de LeĂłn, Guanjuato; RamĂ­rez, GutiĂ©rrez y Figueroa realizan un estudio acerca de la economĂ­a del maĂ­z en la regiĂłn metropolitana, Chiapas, 2014; Bueno, MĂ©ndez y Cruz realizan un estudio y anĂĄlisis de los centros de educaciĂłn y cultura ambiental, necesidad de profesionalizaciĂłn PedagĂłgica de facilitadores ambientales; Pat, Caamal, JerĂłnimo y Mendoza presentan un estudio acerca de los Costos y competitividad de la producciĂłn del limĂłn persa en el municipio de MartĂ­nez de la Torre, Veracruz. Vizuet presenta un trabajo de la construcciĂłn polisĂ©mica e histĂłrica del concepto de la pobreza; Navarrete, RĂ­os y ArĂ©valo presentan un estudio acerca de la producciĂłn ejidal de tomate rojo (Lycopersicum esculentum) en el DR-017, y su huella hĂ­drica; PĂ©rez y Piña hablan acerca de la productividad e inversiĂłn extranjera: La industria de Alimentos; PĂ©rez, Figueroa, GodĂ­nez y GĂłmez presentan el trabajo sobre el sector primario en MĂ©xico; PĂ©rez, Figueroa, GodĂ­nez y GĂłmez presentan acerca de los subsidios al campo como instrumento de polĂ­tica econĂłmica en MĂ©xico; Venegas, Perales y Del Valle realizan un estudio de rentabilidad de biodigestores y motogeneradores para diferentes tamaños de granjas porcinas en MichoacĂĄn

    Ciencias Sociales: EconomĂ­a y Humanidades HANDBOOK T-I

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    Se presenta un breve examen de la producciĂłn y comercializaciĂłn de rosa en MĂ©xico; un estudio en MĂ©xico sobre el ingreso mĂ­nimo de las familias que identifica la lĂ­nea de pobreza alimentaria en el ĂĄrea rural del sur de MĂ©xico, 2012; un pequeño estudio donde hablarĂĄ sobre el anĂĄlisis comparado del Sector Gubernamental y la EconomĂ­a Mexicana desde la perspectiva de los eslabonamientos productivos Hirshman-Rasmuss; un estudio sobre los canales de comercializaciĂłn de limĂłn persa en el municipio de MartĂ­nez de la Torre, Veracruz; una anĂĄlisis del comercio estratĂ©gico en el TLCAN: El Estado en la polĂ­tica agrĂ­cola de biocombustibles; tambiĂ©n se expresan acerca de la importancia de la comercializaciĂłn del cafĂ© en MĂ©xico; un diagnĂłstico, retos del comercio electrĂłnico en el Sector Agroindustrial Mexicano; trabajo nos muestra y habla sobre la inversiĂłn extranjera directa y su impacto en crecimiento de MĂ©xico, un anĂĄlisis en prospectiva: 1999-2010; un estudio acerca sobre la importancia de la Banca en MĂ©xico; un trabajo acerca de la competitividad de la producciĂłn agrĂ­cola en MĂ©xico, un anĂĄlisis regional; se analizan todo acerca de el SIAL productor de quesos en Poxtla, competividad y territorio; se habla acerca de la intermediaciĂłn financiera al servicio de la comunidad indĂ­gena: el fondo regional indĂ­gena Tarhiata Keri; ademas un estudio acerca de la demanda de Importaciones de durazno (Prunus pĂ©rsica L. Batsch) en MĂ©xico procedentes de Estados Unidos de AmĂ©rica (1982-2011); Loera y SepĂșlveda analizan los parĂĄmetros de la productividad forestal en la producciĂłn de madera en rollo; un anĂĄlisis de factores sociales, ambientales y econĂłmicos del territorio rural cercano a la ciudad de MĂ©xico; un estudio acerca de la crisis econĂłmica mundial y su efecto sobre los flujos migratorios de AmĂ©rica Latina; MagadĂĄn, HernĂĄndez y Escalona presentan la tipologĂ­a de los sujetos sociales que intervienen en el mercado campesino de OcotlĂĄn Oaxaca; la normalizaciĂłn del proceso de compostaje: una opciĂłn para desarrollar el mercado de la composta; acerca de la reestructuraciĂłn del capitalismo y crisis polĂ­tica en MĂ©xico; la rentabilidad de la producciĂłn de miel en el municipio de LeĂłn, Guanjuato; la economĂ­a del maĂ­z en la regiĂłn metropolitana, Chiapas, 2014; anĂĄlisis de los centros de educaciĂłn y cultura ambiental, necesidad de profesionalizaciĂłn PedagĂłgica de facilitadores ambientales; los Costos y competitividad de la producciĂłn del limĂłn persa en el municipio de MartĂ­nez de la Torre, Veracruz

    Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

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    Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≄ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

    Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

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    Background: Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods: For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings: Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8-13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05-6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50-75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation: Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life

    Proponer un modelo de control de inventarios, mediante un manual de procedimientos, basado en la norma ISO 9001:2015 de una imprenta.

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    Tesis (Ingeniería Industrial y Licenciatura en Administración Industrial), Instituto Politécnico Nacional, UPIICSA, 2018, 1 archivo PDF, (98 påginas). tesis.ipn.m

    Sistema Excretor - ME150 - 202102

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    El curso revisa desde una visión integral, el desarrollo, estructura, función y disfunción del riñón y las vías urinarias. Las actividades de aprendizaje estån diseñadas para que los estudiantes utilicen los conocimientos en sus explicaciones sobre los fundamentos del sistema excretor y de sus patologías mås frecuentes. Curso de especialidad de la carrera de Medicina, de caråcter teórico-pråctico dirigido a los estudiantes del cuarto nivel de la malla curricular, que busca desarrollar la competencia general de Pensamiento Crítico. Este curso pertenece a la línea del conocimiento de Estructura y Función. Este curso brinda las bases de la pråctica clínica y en los cursos siguientes se desarrolle la competencia de diagnóstico, prevención y promoción

    Sistema Excretor - ME150 201901

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    El curso revisa desde una visión integral, el desarrollo, estructura, función y disfunción del riñón y las vías urinarias. Las actividades de aprendizaje estån diseñadas para que los estudiantes utilicen los conocimientos en sus explicaciones sobre los fundamentos del sistema excretor y de sus patologías mås frecuentes. Curso de especialidad de la carrera de Medicina, de caråcter teórico-pråctico dirigido a los estudiantes del cuarto nivel de la malla curricular, que busca desarrollar la competencia específica de Profesionalismo en su dimensión aprendizaje autónomo y desarrollo profesional (nivel 1). Este curso pertenece a la línea del conocimiento de Estructura y Función. Este curso brinda las bases de la pråctica clínica y en los cursos siguientes se desarrolle la competencia de diagnóstico, prevención y promoción

    Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database

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    Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p &lt; 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p &lt; 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013

    Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

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    Background Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≀1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≄7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates

    Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

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    International audienceBackground: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≀1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≄7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society
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