“Los cinco reinos”. Diseño de materiales usando las nuevas tecnologías y evaluación de aprendizajes

La tesi realitzada ha tingut com a objectiu estudiar l'eficàcia del procés d'aprenentatge experimentat en un grup d'estudiants mitjançant una metodologia que utilitza com a recurs bàsic les Tecnologies de la informació i la comunicació, TIC, desenvolupada en grups cooperatius. En concret, s'ha investigat el nivell adquirit en les competències científica i digital a partir de la unitat didàctica Els Cinc Regnes organitzada en cinc blocs (Ésser viu, Regne Monera, Regne Protista i Virus, Regne Fongs, Regne Vegetal i Regne Animal).The thesis has been carried out aimed at studying the effectiveness of the learning process experienced a group of students through a methodology that uses as a basic resource Technologies information and communication, ICT, developed in cooperative groups. Specifically, it has been investigated the level acquired in the scientific and digital skills from the teaching unit's Five Kingdoms organized into five blocks (living Being, United Monera, Protista and Virus Kingdom, Kingdom Fungi, Plant Kingdom and Animal Kingdom).La tesis realizada ha tenido como objetivo estudiar la eficacia del proceso de aprendizaje experimentado en un grupo de estudiantes mediante una metodología que utiliza como recurso básico las Tecnologías de la información y la comunicación, TIC, desarrollada en grupos cooperativos. En concreto, se ha investigado el nivel adquirido en las competencias científica y digital a partir de la unidad didáctica Los Cinco Reinos organizada en cinco bloques (Ser vivo, Reino Monera, Reino Protista y Virus, Reino Hongos, Reino Vegetal y Reino Animal)

Pero ¿cómo te ha dado por leer traducciones? Algunas consideraciones sobre el estudio de la literatura traducida

En apenas un cuarto de siglo, la traducción —y especialmente la traducción literaria— ha pasado de ser una simple copia, un producto de segundo grado, resultante de un ejercicio mecánico de transferencia lingüística a considerarse un texto autónomo condicionado por e incorporado en unos parámetros culturales y estéticos distintos al original. Este cambio de mentalidad ha sido debido, entre otros factores, al avance y desarrollo de los estudios de traducción desde enfoques prescriptivos a acercamientos de corte empírico orientados al texto y sistema meta. El objetivo del presente artículo es destacar la importancia que estas investigaciones descriptivas han tenido tanto en la evolución del concepto de traducción, como en el reconocimiento del papel que ha desempeñado la traducción en la configuración de las culturas receptoras y señalar las funciones básicas que han venido cumpliendo a lo largo de la historia.In the last three decades, translation —specifically literary translation— after being conceived as a mere copy, a second rate product, result of a mechanical exercise of linguistic transfer, is now being taken up as an autonomous text conditioned by and incorporated within a set of aesthetic and cultural parameters different from the original one. This change of focus is due, among other reasons, to the development of translation studies from prescriptive approaches to empirical and target-oriented ones. The aim of this paper is to emphasize the importance of these descriptive studies in the evolution of the notion of translation. Likewise we will be examining the role that translation has played in the articulation of target cultures and try to point out its basic functions throughout history

Familial pulmonary fibrosis is the strongest risk factor for idiopathic pulmonary fibrosis

SummaryIdiopathic pulmonary fibrosis (IPF) is a lethal lung disorder of unknown etiology. The disease is likely the result of complex interactions between genetic and environmental factors. Evidence suggests that certain environmental factors, such as cigarette smoking and metal dust exposures, or comorbidities like gastroesophageal reflux, and type 2 diabetes mellitus (DM2) may increase risk to develop IPF. Substantial uncertainty remains, however, regarding these and other putative risk factors for IPF. In this study we performed a case–control analysis including 100 patients with IPF and 263 controls matched for age sex and place of residence. We used a structured questionnaire to identify potential risk factors for IPF, including environmental and occupational exposures as well as the relevance of family history of pulmonary fibrosis. The multivariate analysis revealed that family history of pulmonary fibrosis [OR = 6.1, CI95% 2.3–15.9; p < 0.0001] was strongly associated with increased risk of IPF. Actually, 20% of the cases reported a parent or sibling with pulmonary fibrosis. Gastroesophageal reflux [OR = 2.9, CI: 1.3–6.6; p = 0.007], former cigarette smoking [OR = 2.5, CI: 1.4–4.6, p = 0.003], and past or current occupational exposure to dusts, smokes, gases or chemicals [OR = 2.8, CI: 1.5–5.5; p = 0.002] were also associated with the disease. Despite being a significant risk factor on univariate analysis DM2 was not significant in multivariate analysis. These findings indicate that family history of pulmonary fibrosis is a strong risk factor for IPF. Also, we confirmed that occupational exposures, gastroesophageal reflux and former smoking increase the risk for this disease

Miositis orbitaria e hipofisitis como manifestaciones de la enfermedad relacionada con IgG4

IgG4 hypophysitis is a pathology found in non-functioning pituitary masses. We present the case of a 52-year-old woman with a history of orbital myositis of unclear etiology who came to our center for headache with alarm criteria and clinical signs of diabetes insipidus. The imaging study showed a pituitary mass causing panhypopituitarism. Analytically it highlights elevated serum levels of IgG4, so with the suspicion of the disease treatment is initiated with corticosteroids, with a great clinical improvement.La hipofisitis por IgG4 es una patología que se encuentra dentro de las masas hipofisaria no funcionantes. Presentamos el caso de una mujer de 52 años con antecedente de miositis orbitaria de etiología no aclarada que acude a nuestro centro por cefalea con criterios de alarma y clínica de diabetes insípida. En el estudio de imagen destaca una masa hipofisaria que provoca un panhipopituitarismo. Analíticamente destaca niveles séricos elevados de IgG4, por lo que ante la sospecha de la enfermedad se inicia tratamiento con corticoesteroides, con una gran mejoría clínica

Guiding in Tertiary Education: A Case Study on Social Networking and E-Learning Platforms

In this paper we present an innovative treatment which involved students’ participation in online blogs in a university course of English for Specific Purposes (ESP). Mediation of teacher-learner through the university e-learning platform (PoliformaT) was used to guide students through social networking etiquette as well as to provide online tuition to reinforce language contents and resources. By means of an integrated analysis which included qualitative and quantitative research, we see the influence of a Computer-Mediated Communication genre on motivation and learning. Questionnaires administered to the students and interviews provided insightful data to the research about the students’ perception of the treatment. Our results suggest that the approach promoted learner engagement and achievement resulting in high quality learning. Additionally, the research shows the effectiveness of the use of the university virtual tool to enhance teacher-student communication and guidance. © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.Montero Fleta, MB.; Pérez Sabater, C. (2014). Guiding in Tertiary Education: A Case Study on Social Networking and E-Learning Platforms. Procedia Social and Behavioral Sciences. 159:410-414. doi:10.1016/j.sbspro.2014.12.398S41041415

Markers of endothelial damage in patients with chronic kidney disease on hemodialysis

Patients with Stage 5 chronic kidney disease who are on hemodialysis (HD) remain in a chronic inflammatory state, characterized by the accumulation of uremic toxins that induce endothelial damage and cardiovascular disease (CVD). Our aim was to examine microvesicles (MVs), monocyte subpopulations, and angiopoietins (Ang) to identify prognostic markers in HD patients with or without diabetes mellitus (DM). A total of 160 prevalent HD patients from 10 centers across Spain were obtained from the Biobank of the Nephrology Renal Network (Madrid, Spain): 80 patients with DM and 80 patients without DM who were matched for clinical and demographic criteria. MVs from plasma and several monocyte subpopulations (CD142+/CD16+, CD14+/CD162+) were analyzed by flow cytometry, and the plasma concentrations of Ang1 and Ang2 were quantified by ELISA. Data on CVD were gathered over the 5.5 yr after these samples were obtained. MV level, monocyte subpopulations (CD14+/CD162+ and CD142+/CD16+), and Ang2-to-Ang1 ratios increased in HD patients with DM compared with non-DM patients. Moreover, MV level above the median (264 MVs/µl) was associated independently with greater mortality. MVs, monocyte subpopulations, and Ang2-to-Ang1 ratio can be used as predictors for CVD. In addition, MV level has a potential predictive value in the prevention of CVD in HD patients. These parameters undergo more extensive changes in patients with DM.Support for this work was provided by Plan Nacional de IDi Proyectos de Investigación en Salud of Instituto de Salud Carlos III (ISCIII)–Subdirección General de Evaluación, Fondos de desarrollo regional (FEDER; PI11/01536, PI12/01489, PI14/00806, PI15/01785); Junta de Andalucía grants (P010-CTS-6337, P11-CTS-7352); and Fundación Nefrológica. P. Buendía, A. Carmona, and C. Luna-Ruiz are fellows from Consejería de Innovacion, Ciencia y Empresa, Junta de Andalucía

Large-scale study on virological and serological prevalence of SARS-CoV-2 in cats and dogs in Spain

The disease produced by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) is currently one of the primary concerns worldwide. Knowing the zoonotic origin of the disease and that several animal species, including dogs and cats, are susceptible to viral infection, it is critical to assess the relevance of pets in this pandemic. Here, we performed a large-scale study on SARS-CoV-2 serological and viral prevalence in cats and dogs in Spain in order to elucidate their role and susceptibility. Samples from animals in contact with COVID-19 positive people and/or compatible symptoms (n = 492), as well as from random animals (n = 1024), were taken. Despite the large number of animals analyzed, only 12 animals (eight dogs and four cats), which represents 0.79% of the total analyzed animals (n = 1516), were positive for viral SARS-CoV-2 RNA detection by reverse transcription quantitative PCR (RT-qPCR) in which viral isolation was possible in four animals. We detected neutralizing antibodies in 34 animals, four of them were also positive for PCR. This study evidences that pets are susceptible to SARS-CoV-2 infection in natural conditions but at a low level, as evidenced by the low percentage of positive animals detected, being infected humans the main source of infection. However, the inclusion of animals in the surveillance of COVID-19 is still recommended.Institute of Health Carlos III (ISCIII), Grant/Award Number: COV20/01385Peer reviewe

Management of a caseous lymphadenitis outbreak in a new Iberian ibex (Capra pyrenaica) stock reservoir

Background: In 2010, an Iberian ibex (Capra pyrenaica hispanica) stock reservoir was established for conservation purposes in north-eastern Spain. Eighteen ibexes were captured in the wild and housed in a 17 hectare enclosure. Once in captivity, a caseous lymphadenitis (CLA) outbreak occurred and ibex handlings were carried out at six-month intervals between 2010 and 2013 to perform health examinations and sampling. Treatment with a bacterin-based autovaccine and penicillin G benzatine was added during the third and subsequent handlings, when infection by Corynebacterium pseudotuberculosis was confirmed. Changes in lesion score, serum anti-C. pseudotuberculosis antibodies and haematological parameters were analyzed to assess captivity effects, disease emergence and treatment efficacy. Serum acute phase proteins (APP) Haptoglobin (Hp), Amyloid A (SAA) and Acid Soluble Glycoprotein (ASG) concentrations were also determined to evaluate their usefulness as indicators of clinical status.Once in captivity, 12 out of 14 ibexes (85.7%) seroconverted, preceding the emergence of clinical signs; moreover, TP, WBC, eosinophil and platelet cell counts increased while monocyte and basophil cell counts decreased. After treatment, casualties and fistulas disappeared and both packed cell volume (PCV) and haemoglobin concentration significantly increased. Hp, SAA and ASG values were under the limit of detection or showed no significant differences. Conclusions: A role for captivity in contagion rate is suggested by the increase in antibody levels against C. pseudotuberculosis and the emergence of clinical signs. Although boosted by captivity, this is the first report of an outbreak of caseous lymphadenitis displaying high morbidity and mortality in wild ungulates. Treatment consisting of both vaccination and antibiotic therapy seemed to prevent mortality and alleviate disease severity, but was not reflected in the humoural response. Haematology and APP were not useful indicators in our study, perhaps due to the sampling frequency. Presumably endemic and irrelevant in the wild, this common disease of domestic small ruminants is complicating conservation efforts for the Iberian ibex in north-eastern Spain

"Los cinco reinos". Diseño de materiales usando las nuevas tecnologías y evaluación de aprendizajes

La tesis realizada ha tenido como objetivo estudiar la eficacia del proceso de aprendizaje experimentado en un grupo de estudiantes mediante una metodología que utiliza como recurso básico las Tecnologías de la información y la comunicación, TIC, desarrollada en grupos cooperativos. En concreto, se ha investigado el nivel adquirido en las competencias científica y digital a partir de la unidad didáctica Los Cinco Reinos organizada en cinco bloques (Ser vivo, Reino Monera, Reino Protista y Virus, Reino Hongos, Reino Vegetal y Reino Animal).The thesis has been carried out aimed at studying the effectiveness of the learning process experienced a group of students through a methodology that uses as a basic resource Technologies information and communication, ICT, developed in cooperative groups. Specifically, it has been investigated the level acquired in the scientific and digital skills from the teaching unit's Five Kingdoms organized into five blocks (living Being, United Monera, Protista and Virus Kingdom, Kingdom Fungi, Plant Kingdom and Animal Kingdom).La tesi realitzada ha tingut com a objectiu estudiar l'eficàcia del procés d'aprenentatge experimentat en un grup d'estudiants mitjançant una metodologia que utilitza com a recurs bàsic les Tecnologies de la informació i la comunicació, TIC, desenvolupada en grups cooperatius. En concret, s'ha investigat el nivell adquirit en les competències científica i digital a partir de la unitat didàctica Els Cinc Regnes organitzada en cinc blocs (Ésser viu, Regne Monera, Regne Protista i Virus, Regne Fongs, Regne Vegetal i Regne Animal)