64 research outputs found

    El pensar del alma: un regalo de la madre

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    No puedo evitar, al plantearme una conferencia en el seminario de Duoda, una reflexión sobre las atribuciones ideológicas -ideológicas, sí- que se hacen a quienes en él colaboran. Digo ideológicas por cuanto, si bien todo pensamiento o todo discurso es un sistema de ideas y el mío por supuesto lo será o tratará de serlo, también se usa este adjetivo para totalizar en uno sólo cualquier sistema de ideas que quiera expresar un pensamiento. Mi primera reflexión pues, es la de que mi intento de sistematizar mis ideas en torno a ese materno tema del Gratis et amare, se produce en una práctica de libertad de pensar, que poco a poco y no sin dificultad, he ido construyéndome a lo largo de mi experiencia personal y profesional, en distintos espacios institucionales y sociales, entre Jos cuajes se ha podido contar éste de Ouoda

    Reviure en relació a l'altre: fer de les classes un inici

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    El text que us presentem té origen en una experiència viscuda per dues professores de Coeducació que, a la mateixa hora i en aules veines, es trobaven amb un grup de noies i nois. Les paraules que segueixen valen continuar reprenent el fil de les que ens dèiem en els minuts que precedien i seguien a les sessions de classe. Així és com les prenem per tal que iniciïn un assaig d'escriure els diàlegs que, primer casuals i després imprescindibles, manteníem amb lànim de compartir l'experiència de ser mestres, d'intercanviar receptes que a una o altra ens anaven bé per a encetar, aprofundir o revisar les possibilitats creadores que porta en sí el partir de la diferència sexual

    Una experiència de partir de sí en un context educatiu

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    Dins deis credits del Master en Estudis de les dones, com a professores de I'assignatura de 'Subjectivitat, experiencia í saber docent', vam propasar per iniciar el trebaU partir de les experiencies que han estat significatives tant en positiu Gom en negatiu en la nostra trajeetoria educativa com a alumnes ¡ com a docents -en el cas de les que ha f055in-. Aquest text que ara presentem és fruit de j'etaboració de les idees que van sorgir en les primeres sessions en que vam compartir, professores i alumnes, les nas tres experiencies educatives1 Els temes més rellevants que van emergir fan referencia a!s tres aspectes que desenvolupem en el text: l'experiencla de partir de sí com a necessitat de nomenar-nos en primera persona; el sentlt de la mediació femenina en la relació educativa; l la negació com a subjectes en I'educació, la negació del desig

    Temperature dependence of plankton community metabolism in the subtropical and tropical oceans

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    Here we assess the temperature dependence of the metabolic rates (gross primary production (GPP), community respiration (CR), and the ratio GPP/CR) of oceanic plankton communities. We compile data from 133 stations of the Malaspina 2010 Expedition, distributed among the subtropical and tropical Atlantic, Pacific, and Indian oceans. We used the in vitro technique to measured metabolic rates during 24 h incubations at three different sampled depths: surface, 20%, and 1% of the photosynthetically active radiation measured at surface. We also measured the % of ultraviolet B radiation (UVB) penetrating at surface waters. GPP and CR rates increased with warming, albeit different responses were observed for each sampled depth. The overall GPP/CR ratio declined with warming. Higher activation energies (Ea) were derived for both processes (GPPChla = 0.97; CRChla = 1.26; CRHPA = 0.95 eV) compared to those previously reported. The Indian Ocean showed the highest Ea (GPPChla = 1.70; CRChla = 1.48; CRHPA = 0.57 eV), while the Atlantic Ocean showed the lowest (GPPChla = 0.86; CRChla = 0.77; CRHPA = 0.13 eV). We believe that the difference between previous assessments and the ones presented here can be explained by the overrepresentation of Atlantic communities in the previous data sets. We found that UVB radiation also affects the temperature dependence of surface GPP, which decreased rather than increased under high levels of UVB. Ocean warming, which causes stratification and oligotrophication of the subtropical and tropical oceans, may lead to reduced surface GPP as a result of increased penetration of UVB radiation.En prens

    Famílies botàniques de plantes medicinals

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    Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica

    Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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    Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have the capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is a deficit in DC numbers and IFN-α production, which has been associated with disease severity. In this work, we described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers. Remarkably, previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+ myeloid DCs and pDCs seven months after SARS-CoV-2 infection. Moreover, the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed. These findings contribute to a better understanding of the immunological sequelae of COVID-19

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Role of age and comorbidities in mortality of patients with infective endocarditis

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    [Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group
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