Distance learning of engineering based subjects: A case study.

YesWith the advancement of technology, significant changes have been introduced into the learning and teaching environment. The importance of enhancing the interest of learners is an on-going challenge for educators of all levels. In this respect, teaching and learning practices are adapting to students¿ exposure to technological and social trends. In this presentation, a case study of using technology to enhance the learners¿ environment for engineering-based subjects in higher education is presented. The approach consists of delivering interactive materials through a Virtual Learning Environment and integrating web application technologies to enhance the learners¿ experience. Due to the vast subject areas in engineering and the variety of content of each subject, a general methodology is first identified and adopted. This consists of stages that show the progress from initial development to deployment of the materials, followed by evaluation of the module and further improvements carried out on the module based on qualitative evaluation. The evaluation process consists of the application of electronic surveys for feedback on the distance learning module. In addition, monitoring of the students¿ usage of the materials is also carried out. The presentation concludes with the presentation of the initial results from a current e-learning module

Evaluating the case for employing E-Portfolio tools during the Final Year Engineering Project

yesThe Final Year Project is an integral part of an engineering degree programme. At the University of Bradford's School of Engineering, Design and Technology (SoEDT), the project spans two semesters and is worth 30 credits or the equivalent of 300 hours of work. A student works under the guidance of a supervisor on a particular topic that usually involves some experimental activity, and is required to apply a variety of personal and technical skills as part of the project process. At Bradford, the Final Year Engineering Project (FYEP) concludes with summative assessment, in terms of a technical report and poster presentation, both of which occur at the end of the second semester. For most students the FYEP represents a new way of working, while the nature of supervision can vary from hugely rewarding to very disappointing. There is possible scope for improving the FYEP experience, from the perspectives of supervisor and student, through the use of e-portfolio tools, which make use of the Web to provide the means for maintaining communication, monitoring progress and developing a student¿s skills portfolio. If e-portfolio tools are to be considered as a possible integral part of the FYEP process, then an appreciation of the current FYEP experience among students and supervisors must first be gained. In this paper, quantitative and qualitative results are presented based on face-to-face semi-structured interviews with academic supervisors and responses to on-line questionnaires from supervisors and final year engineering students at the SoEDT. The results provide an insight into the practices and techniques employed as part of the FYEP, and identify where training is needed to develop particular project skills. The results provide a basis for the development of an e-portfolio application that supports the FYEP experience, which is introduced to conclude the paper.National HE STEM Programm

Resource Reservation protocol Tunnelling Extension in MPLS for sustainable Mobile Wireless Networks

Traffic Engineering (TE) is most effective in networks where some links are heavily utilized and have little or no bandwidth available while others carry little or no traffic. It is of great importance to the recent development of mobile and wireless technologies. Without the process of TE, there is possibilities of having under-utilization and over-utilization problems along the links. It is necessary to consider the implementation that would avoid the goal of network and unguaranteed bandwidth delivery. Therefore, the operators and service providers require seamless combination of network protocols with an improved quality of service (QoS). This paper will be focusing on Resource Reservation Protocol Tunnelling Extension Multiprotocol Layer Switching (RSVP-TE MPLS) for sustainable mobile wireless networks. This will make provision of bandwidth allocation possible by implementing the configurations of the dynamic and static LSPs (Label Switching Paths). The network model designed will be used for this purpose by using simulation approach. The verification of the MPLS model will be presented. It will eventually maximize bandwidth utilization, minimize operation cost and improve QoS

Heterogeneous Networking for Beyond 3G system in a High-Speed Train Environment. Investigation of handover procedures in a high-speed train environment and adoption of a pattern classification neural-networks approach for handover management

Based on the targets outlined by the EU Horizon 2020 (H2020) framework, it is expected that heterogeneous networking will play a crucial role in delivering seamless end-to-end ubiquitous Internet access for users. In due course, the current GSM-Railway (GSM-R) will be deemed unsustainable, as the demand for packet-oriented services continues to increase. Therefore, the opportunity to identify a plausible replacement system conducted in this research study is timely and appropriate. In this research study, a hybrid satellite and terrestrial network for enabling ubiquitous Internet access in a high-speed train environment is investigated. The study focuses on the mobility management aspect of the system, primarily related to the handover management. A proposed handover strategy, employing the RACE II MONET and ITU-T Q.65 design methodology, will be addressed. This includes identifying the functional model (FM) which is then mapped to the functional architecture (FUA), based on the Q.1711 IMT-2000 FM. In addition, the signalling protocols, information flows and message format based on the adopted design methodology will also be specified. The approach is then simulated in OPNET and the findings are then presented and discussed. The opportunity of exploring the prospect of employing neural networks (NN) for handover is also undertaken. This study focuses specifically on the use of pattern classification neural networks to aid in the handover process, which is then simulated in MATLAB. The simulation outcomes demonstrated the effectiveness and appropriateness of the NN algorithm and the competence of the algorithm in facilitating the handover process

Systematic analysis of secreted proteins reveals synergism between IL6 and other proteins in soft agar growth of MCF10A cells

<p>Abstract</p> <p>Introduction</p> <p>Breast cancer, the most common malignancy in women, still holds many secrets. The causes for non-hereditary breast cancer are still unknown. To elucidate any role for circulating naturally secreted proteins, a screen of secreted proteins' influence of MCF10A cell anchorage independent growth was set up.</p> <p>Methods</p> <p>To systematically screen secreted proteins for their capacity to transform mammalian breast epithelial cells, a soft agar screen of MCF10A cells was performed using a library of ~ 470 secreted proteins. A high concentration of infecting viral particles was used to obtain multiple infections in individual cells to specifically study the combined effect of multiple secreted proteins.</p> <p>Results</p> <p>Several known breast cancer factors, such as Wnt, FGF and IL were retained, as well as factors that were previously unknown to have a role in breast cancer, such as paraoxonase 1 and fibroblast growth factor binding protein 2. Additionally, a combinatory role of Interleukin 6 with other factors in MCF10A anchorage-independent growth is demonstrated.</p> <p>Conclusion</p> <p>The transforming effect of combinations of IL6 with other secreted proteins allows studying the transformation of mammary epithelial cells <it>in vitro</it>, and may also have implications in <it>in vivo </it>studies where secreted proteins are upregulated or overexpressed.</p

Design of mobile band subsurface antenna for drainage infrastructure monitoring

This paper presents an underground subsurface wireless sensor for drainage infrastructure water level monitoring. It operates from 800 to 2170 MHz to cover the required GSM850/900, GSM1800/1900 and UMTS bands. The system consists of a wideband antenna, transceiver, data acquisition unit and an ultrasonic sensor. The proposed antenna is a 3-dimensional inverted double F antenna and has an envelope size of 90 × 63.5 × 32 mm^3 , which is acceptably small for a cramped subsurface passageway environment. The antenna design was developed using software simulation to optimise its key parameters of return loss and radiation pattern, these being evaluated both in free space and in the partially underground environment. The design developed was then realised in hardware and tested in a representative subsurface location: a utility manhole chamber. It was found that the location of the antenna in the chamber had a significant effect on its performance, but a location that was acceptable for operational purposes was found by experiment. The overall system, including a transceiver, was demonstrated to operate satisfactorily for utility monitoring purposes, including acceptable levels of path loss for communication with mobile communication base stations

A diverse view of science to catalyse change

Valuing diversity leads to scientific excellence, the progress of science and, most importantly, it is simply the right thing to do. We must value diversity not only in words, but also in actions

A diverse view of science to catalyse change:Valuing diversity leads to scientific excellence, the progress of science and, most importantly, it is simply the right thing to do. we must value diversity not only in words, but also in actions

No abstract available.publishe

Increasing access to integrated ESKD care as part of Universal Health Coverage

The global nephrology community recognizes the need for a cohesive strategy to address the growing problem of end-stage kidney disease (ESKD). In March 2018, the International Society of Nephrology hosted a summit on integrated ESKD care, including 92 individuals from around the globe with diverse expertise and professional backgrounds. The attendees were from 41 countries, including 16 participants from 11 low- and lower-middle–income countries. The purpose was to develop a strategic plan to improve worldwide access to integrated ESKD care, by identifying and prioritizing key activities across 8 themes: (i) estimates of ESKD burden and treatment coverage, (ii) advocacy, (iii) education and training/workforce, (iv) financing/funding models, (v) ethics, (vi) dialysis, (vii) transplantation, and (viii) conservative care. Action plans with prioritized lists of goals, activities, and key deliverables, and an overarching performance framework were developed for each theme. Examples of these key deliverables include improved data availability, integration of core registry measures and analysis to inform development of health care policy; a framework for advocacy; improved and continued stakeholder engagement; improved workforce training; equitable, efficient, and cost-effective funding models; greater understanding and greater application of ethical principles in practice and policy; definition and application of standards for safe and sustainable dialysis treatment and a set of measurable quality parameters; and integration of dialysis, transplantation, and comprehensive conservative care as ESKD treatment options within the context of overall health priorities. Intended users of the action plans include clinicians, patients and their families, scientists, industry partners, government decision makers, and advocacy organizations. Implementation of this integrated and comprehensive plan is intended to improve quality and access to care and thereby reduce serious health-related suffering of adults and children affected by ESKD worldwide

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely