Physiotherapy in burned patients: burned patients,therapist treatment and realted aspects

[Resumen] Este artículo tiene como objetivos, analizar las causas principales de las grandes quemaduras, de los pacientes ingresados en el Instituto del Quemado de Córdoba-Argentina, en el periodo de tiempo comprendido entre Enero de 2000 y Enero de 2001. Además de analizar la evolución de los autoinjertos, complicaciones más frecuentes, trastornos psiquiátricos asociados, morbimortalidad registrada, etc. presentamos una propuesta de tratamiento de fisioterapia adecuado al tipo y/o profundidad de la(s) quemadura(s). Para ello, se ha analizado una muestra de 100 historias clínicas, de pacientes ingresados en el Instituto del Quemado de Córdoba-Argentina, durante el periodo de tiempo antes señalado, y se ha realizado una revisión bibliográfica exhaustiva, que nos ha sido de utilidad para fundamenta la propuesta de tratamiento.[Abstract] The aims of this article is to analyze the mains reasons of the important burns in the patients being admitted to the Burned people Institute in Cordoba, Argentina between January of 2000 and 2001 year. We explain not only the progress of the skin graft, the more common complications, the associated psyquiatric problems, the registred morbility, etc... but also the plan of treatment suitable for the type and the deep of the burn. We have analyze a sample of 100 case histories related to admitted patients to the Burned people Institute in Cordoba, Argentina. After that, we have made a comprehensive bibliographic cheeking, which has been very useful to base the protocol of the treatment

El sociodrama como técnica de intervención socioeducativa.

Sin resume

Acidosis tubular renal como presentación clínica de Síndrome de Sjögren: reporte de caso

Presentamos el caso clínico de una mujer en la quinta década de la vida, de nacionalidad argentina, que acudió a la guardia de clínica médica de un hospital de tercer nivel por cuadro de mialgias y paresia en las cuatro extremidades, de inicio agudo, progresivo, con dificultad para la movilización de miembros superiores, bipedestación y marcha. Se constató hipocalemia severa, acidosis metabólica, pH urinario alcalino, brecha aniónica urinaria positiva (excreción de amonio), hipocitraturia e hipercalciuria, por lo que se diagnosticó Acidosis Tubular Renal (ATR) tipo I; además se evidenció elevación de creatinkinasa (CK) e insuficiencia renal aguda que corrigió con la reposición de líquidos. Al interrogatorio dirigido, la paciente refirió síndrome seco asociado a artralgias, de varios años de evolución, por lo que se realizaron estudios complementarios que apoyaron el diagnóstico de Síndrome de Sjögren

Millennial surface water dynamics in the Ría de Vigo during the last 3000 years as revealed by coccoliths and molecular biomarkers

13 pages, 7 figures, 2 tables.-- Printed version published Mar 10, 2005.A combined study of coccolith assemblages and biomarkers in a gravity core collected from the Ría de Vigo (NW Spain) allowed us to reconstruct the paleoenvironmental conditions for the last 3000 years. The quantitative distribution of coccolithophore species points to three different intervals within the core, dated by AMS radiocarbon measurements. The first interval (ca. 975 BC–252 AD), characterized by high abundances of Calcidiscus leptoporus and Gephyrocapsa muellerae, is thought to represent moderate water temperatures, suggesting a transition from a warmer to a cooler period. The second interval (ca. 252–1368 AD), characterized by the dominance of Coccolithus pelagicus, Helicosphaera carteri and Syracosphaera spp., and a high concentration of hexacosanol linked to terrestrial input, is interpreted as having been a humid period with fluvial input. The third interval (ca. 1368 AD–1950) is characterized by a high abundance of Gephyrocapsa oceanica, high alkenone values and low values of hexacosanol, and is thought to represent a period dominated by oceanic conditions within the Ría.Taking into account the ocean–atmospheric system affecting the region studied, here we propose an alternation in the mean state of North Atlantic Oscillation (NAO) at millennial time scales. A well-developed upwelling system and an active Ría–ocean connection during the warmer interval I suggest a NAO+ phase influenced by a Hypsithermal period. The occurrence of the humid and relatively warm interval II is consistent with a negative phase in the NAO, as well as a relative restriction in ocean–Ría exchange. Interval III, which was drier and more productive, again suggests the dominance of a positive phase in the NAO, with a more intense oceanic connection and more energized upwelling.Research grants ABRUMIS REN2003-08642-C02-02/CLI, BTE2002-04670 (Ministerio de Ciencia y Tecnología) and SA088/04 (Junta de Castilla y León) supported this study.Peer reviewe

Periodontal Condition and Subgingival Microbiota Characterization in Subjects with Down Syndrome

The aim was to study the subgingival microbiota in subjects with Down syndrome (DS) with different periodontal health status, using cultural and molecular microbiological methods. In this cross-sectional study, DS subjects were selected among those attending educational or occupational therapy centers in Galicia (Spain). Medical histories, intraoral and periodontal examinations and microbiological sampling were performed. Samples were processed by means of culture and quantitative polymerase chain reaction (qPCR). Microbiological data were compared, by one-way ANOVA or Kruskal-Wallis and chi-square or Fisher tests, according to their periodontal status. 124 subjects were included, 62 with a healthy periodontium, 34 with gingivitis and 28 with periodontitis. Patients with periodontitis were older (p < 0.01) and showed lower prevalence of hypothyroidism and levothyroxine intake (p = 0.01), presented significantly deeper pockets and more attachment loss (p ≤ 0.01). Both gingivitis and periodontitis subjects showed higher levels of bleeding and dental plaque. PCR counts of T. forsythia and culture counts of E. corrodens and total anaerobic counts were significantly higher in periodontitis patients. Relevant differences were observed in the subgingival microbiota of DS patients with periodontitis, showing higher levels of anaerobic bacteria, T. forsythia and E. corrodens, when compared with periodontally healthy and gingivitis subjects. Moreover, periodontitis subjects were older, had lower frequency of hypothyroidism and higher levels of dental plaqueThis project was co-funded by Xunta de Galicia under Ignicia Programme, Axencia Galega de Innovación, GAIN (12/08/2016; GRANT_NUMBER: IN855A). The participation of M.C. Sánchez in the project occurred within the activities of the Extraordinary Chair of DENTAID in Periodontal Research, University Complutense of Madrid, SpainS

SEOM clinical guidelines on nutrition in cancer patients (2018)

Nutritional deficiency is a common medical problem that affects 15-40% of cancer patients. It negatively impacts their quality of life and can compromise treatment completion. Oncological therapies, such as surgery, radiation therapy, and drug therapies are improving survival rates. However, all these treatments can play a role in the development of malnutrition and/or metabolic alterations in cancer patients, induced by the tumor or by its treatment. Nutritional assessment of cancer patients is necessary at the time of diagnosis and throughout treatment, so as to detect nutritional deficiencies. The Patient-Generated Subjective Global Assessment method is the most widely used tool that also evaluates nutritional requirements. In this guideline, we will review the indications of nutritional interventions as well as artificial nutrition in general and according to the type of treatment (radiotherapy, surgery, or systemic therapy), or palliative care. Likewise, pharmacological agents and pharmaconutrients will be reviewed in addition to the role of regular physical activity

Structure-Related Differences between Cytochrome Oxidase I Proteins in a Stable Heteroplasmic Mitochondrial System

open5siMIUR, programma SIR, progetto n. RBSI14G0P5 "MItochoNdria, Germ Line and sEx" (MINGLE)Many bivalve species have two types of mitochondrial DNA passed independently through the female line (F genome) and male line (M genome). Here we study the cytochrome oxidase I protein in such bivalve species and provide evidence for differences between the F and M proteins in amino acid property values, particularly relating to hydrophobicity and helicity. The magnitude of these differences varies between different regions of the protein and the change from the ancestor is most marked in the M protein. The observed changes occur in parallel and in the same direction in the different species studied. Two possible causes are considered, first relaxation of purifying selection with drift and second positive selection. These may operate in different ways in different regions of the protein. Many different amino acid substitutions contribute in a small way to the observed variation, but substitutions involving alanine and serine have a quantitatively large effect. Some of these substitutions are potential targets for phosphorylation and some are close to residues of functional importance in the catalytic mechanism. We propose that the observed changes in the F and M proteins might contribute to functional differences between them relating to ATP production and mitochondrial membrane potential with implications for sperm function.openSkibinski, David O F; Ghiselli, Fabrizio; Diz, Angel P; Milani, Liliana; Mullins, Jonathan G LSkibinski, David O F; Ghiselli, Fabrizio; Diz, Angel P; Milani, Liliana; Mullins, Jonathan G

Alteración termoxidativa en un aceite de girasol utilizado en 75 frituras de patatas

The alteration of a sunflower oil used in 75 repeated deep fat frying of potatoes performed with addition of unused oil every 4-5 fryings with the aim to keep constant the proportion food/oil in 500 g / 3 liters, was evaluated by column and high performance size exclusion chromatographies. The polar components increased from 5.09 ± 0.21 (unused oil) to 19.11 ± 0,40 mg/100 mg oil mainly due to the formation of polymers and dimers of triacylglycerides, and to oxidized triacylglycerides. Oils, unused and from the 75 frying, were included at a rate of 15% on rat-diets. Dietary food intakes were similar, however body weight gain was a 22.3% lower in rat fed with the used oil-diet. Apparent digestibility ratios of fat and protein were similar in both groups of rats, however both. Alimentary and Protein Efficiency ratios decreased on the 75 frying oil fed rats.Se evalúa la alteración de un aceite de girasol utilizado en 75 frituras repetidas de patatas, efectuadas con adición de aceite sin usar cada 4-5 frituras con la finalidad de mantener constante la proporción alimento/aceite en 500 g / 3 litros, mediante cromatografías en columna y de alta eficacia por exclusión de tamaño de partícula. El contenido de los compuestos polares se incrementó de 5.09 ± 0.21 (aceite sin usar) a 19.11 ± 0.40 mg/100 mg de aceite, predominando los polímeros y dímeros de triacilglicéridos y los triacilglicéridos oxidados. Dichos aceites, sin usar y utilizado en 75 frituras, se incluyeron en la proporción del 15% en las dietas del lote basal y del lote fritura 75, respectivamente. La ingesta de ambas dietas fue similar, pero la ganancia de peso resultó ser un 22,3% menor en el lote fritura 75. Los coeficientes de digestibilidad aparente de grasa y proteína fueron similares en ambos lotes, pero la utilización nutritiva en términos de coeficientes de Eficacia Alimentaria y Proteica fue menor en el lote fritura 75

RNA-seq coupled to proteomic analysis reveals high sperm proteome variation between two closely related marine mussel species

(a) RNA based approach to assess genomic differences between a Welsh and Spanish species of Mussell. Protein based analysis also carried out, both in gonad tissue. Not too sure why DNA based approaches not used? Clearly differences were observed. Lots of detailed analysis of differentially expressed genes. Not too sure about the significance of this data - this could be my lack of understanding. (b) Technically very competent transcriptomic and proteomic analysis of marine mussel sperm. However, the paper does not really get to grips with the underlying biological problem: that the two species studied are only partly reproductively isolated. With some hybridization being possible. This is discussed briefly in section 4.3.3, but the conclusions are very much in the form of hypothetical but undecided possibilities; as, indeed, are the conclusions generally

Biophysics across time and space

Understanding the behaviour of almost any biological object is a fundamentally multiscale problem — a challenge that biophysicists have been increasingly embracing, building on two centuries of biophysical studies at a variety of length scales