311 research outputs found
Periodic Modulations in an X-ray Flare from Sagittarius A*
We present the highly significant detection of a quasi-periodic flux
modulation with a period of 22.2 min seen in the X-ray data of the Sgr A* flare
of 2004 August 31. This flaring event, which lasted a total of about three
hours, was detected simultaneously by EPIC on XMM-Newton and the NICMOS
near-infrared camera on the HST. Given the inherent difficulty in, and the lack
of readily available methods for quantifying the probability of a periodic
signal detected over only several cycles in a data set where red noise can be
important, we developed a general method for quantifying the likelihood that
such a modulation is indeed intrinsic to the source and does not arise from
background fluctuations. We here describe this Monte Carlo based method, and
discuss the results obtained by its application to a other XMM-Newton data
sets. Under the simplest hypothesis that we witnessed a transient event that
evolved, peaked and decayed near the marginally stable orbit of the
supermassive black hole, this result implies that for a mass of 3.5 x 10^{6}
Msun, the central object must have an angular momentum corresponding to a spin
parameter of a=0.22.Comment: 4 pages, 6 figures, submitted to ApJ
The Broadband Spectrum of Galaxy Clusters
We examine whether nonthermal protons energized during a cluster merger are
simultaneously responsible for the Coma cluster's diffuse radio flux (via
secondary decay) and the departure of its intra-cluster medium (ICM) from a
thermal profile via Coulomb collisions between the quasithermal electrons and
the hadrons. Rather than approximating the influence of nonthermal
proton/thermal electron collisions as extremely rare events which cause an
injection of nonthermal, power-law electrons (the `knock-on' approximation), we
self-consistently solve (to our knowledge, for the first time) the covariant
kinetic equations for the two populations. The electron population resulting
from these collisions is out of equilibrium, yet not a power law, and
importantly displays a higher bremsstrahlung radiative efficiency than a pure
power law. Observations with GLAST will test this model directly.Comment: Accepted for publication in Ap
The AGASA/SUGAR Anisotropies and TeV Gamma Rays from the Galactic Center: A Possible Signature of Extremely High-energy Neutrons
Recent analysis of data sets from two extensive air shower cosmic ray
detectors shows tantalizing evidence of an anisotropic overabundance of cosmic
rays towards the Galactic Center (GC) that ``turns on'' around eV. We
demonstrate that the anisotropy could be due to neutrons created at the
Galactic Center through charge-exchange in proton-proton collisions, where the
incident, high energy protons obey an power law associated with
acceleration at a strong shock. We show that the normalization supplied by the
gamma-ray signal from EGRET GC source 3EG J1746-2851 -- ascribed to pp induced
neutral pion decay at GeV energies -- together with a very reasonable spectral
index of 2.2, predicts a neutron flux at eV fully consistent
with the extremely high energy cosmic ray data. Likewise, the normalization
supplied by the very recent GC data from the HESS air-Cerenkov telescope at
\~TeV energies is almost equally-well compatible with the eV
cosmic ray data. Interestingly, however, the EGRET and HESS data appear to be
themselves incompatible. We consider the implications of this discrepancy. We
discuss why the Galactic Center environment can allow diffusive shock
acceleration at strong shocks up to energies approaching the ankle in the
cosmic ray spectrum. Finally, we argue that the shock acceleration may be
occuring in the shell of Sagittarius A East, an unusual supernova remnant
located very close to the Galactic Center. If this connection between the
anisotropy and Sagittarius A East could be firmly established it would be the
first direct evidence for a particular Galactic source of cosmic rays up to
energies near the ankle.Comment: 57 pages, 2 figure
Patients’ and caregivers’ contested perspectives on spiritual care for those affected by advanced illnesses: A qualitative descriptive study
Context; Spiritual care refers to practices and rituals addressing spiritual/religious concerns. It supports coping with loss and finding hope, meaning, and peace. Although integral to palliative care, its implementation is challenging.
Objective: To understand an Australian cohort of patients’ and caregivers’ perspectives about experiencing and optimizing spiritual care in the context of advanced illness.
Methods: Patients and caregivers of patients with #12 month prognosis were recruited from a broader spiritual study via criterion sampling and agreed to opt-in interviews. Participants from an Australian, metropolitan health service received a spiritual care definition and were interviewed. Transcripts were analyzed using qualitative description.
Results: 30 patients (17 male; mean age 70 years) and 10 caregivers (six male; mean age 58.9 years) participated. 27 identified as Christian, and 10 had no religion. Participants described multifaceted and contested beliefs about spirituality. Many queried the tangibility of spirituality, but all valued respectful staff who affirmed personhood, that is, each individual’s worth, especially when care exceeded expectations. They also resonated with positive organizational and environmental tones that improved holistic well-being. Participants stressed the importance of the hospital’s welcoming context and skilled care, which comforted and reassured.
Conclusion: Although many patients and caregivers did not resonate with the term ‘‘spiritual care,’’ all described how the hospital’s hospitality could affirm their values and strengthen coping. The phrase ‘‘spiritual care and hospitality’’ may optimally articulate and guide care in similar, pluralist inpatient palliative care contexts, recognizing that such care encompasses an interplay of generalist and specialist pastoral care staff and organizational and environmental qualities
Timing of palliative care referral and aggressive cancer care toward the end-of-life in pancreatic cancer: A retrospective, single-center observational study
Background: Pancreatic cancer is noted for its late presentation at diagnosis, limited prognosis and physical and psychosocial symptom burden. This study examined associations between timing of palliative care referral (PCR) and aggressive cancer care received by pancreatic cancer patients in the last 30 days of life through a single health service.
Method: A retrospective cohort analysis of end-of-life (EOL) care outcomes of patients with pancreatic cancer who died between 2012 and 2016. Key indicators of aggressive cancer care in the last 30 days of life used were: ≥1 emergency department (ED) presentations, acute inpatient/intensive care unit (ICU) admission, and chemotherapy use. We examined time from PCR to death and place of death. Early and late PCR were defined as \u3e 90 and ≤ 90 days before death respectively.
Results: Out of the 278 eligible deaths, 187 (67.3%) were categorized as receiving a late PCR and 91 (32.7%) an early PCR. The median time between referral and death was 48 days. Compared to those receiving early PCR, those with late PCR had: 18.1% (95% CI 6.8–29.4%) more ED presentations; 12.5% (95% CI 1.7–24.8%) more acute hospital admissions; with no differences in ICU admissions. Pain and complications of cancer accounted for the majority of overall ED presentations. Of the 166 patients who received chemotherapy within 30 days of death, 23 (24.5%) had a late PCR and 12 (16.7%) an early PCR, with no association of PCR status either unadjusted or adjusted for age or gender. The majority of patients (55.8%) died at the inpatient palliative care unit.
Conclusion: Our findings reaffirm the benefits of early PCR for pancreatic cancer patients to avoid inappropriate care toward the EOL. We suggest that in modern cancer care, there can sometimes be a need to reconsider the use of the term ‘aggressive cancer care’ at the EOL when the care is appropriately based on an individual patient’s presenting physical and psychosocial needs. Pancreatic cancer patients warrant early PCR but the debate must thus continue as to how we best achieve and benchmark outcomes that are compatible with patient and family needs and healthcare priorities
On the development of QPOs in Bondi-Hoyle accretion flows
The numerical investigation of Bondi-Hoyle accretion onto a moving black hole
has a long history, both in Newtonian and in general-relativistic physics. By
performing new two-dimensional and general-relativistic simulations onto a
rotating black hole, we point out a novel feature, namely, that quasi-periodic
oscillations (QPOs) are naturally produced in the shock cone that develops in
the downstream part of the flow. Because the shock cone in the downstream part
of the flow acts as a cavity trapping pressure perturbations, modes with
frequencies in the integer ratios 2:1 and 3:1 are easily produced. The
frequencies of these modes depend on the black-hole spin and on the properties
of the flow, and scale linearly with the inverse of the black-hole mass. Our
results may be relevant for explaining the detection of QPOs in Sagittarius A*,
once such detection is confirmed by further observations. Finally, we report on
the development of the flip-flop instability, which can affect the shock cone
under suitable conditions; such an instability has been discussed before in
Newtonian simulations but was never found in a relativistic regime.Comment: 11 pages, 7 figure
Diffuse Gamma-ray Emission from the Galactic Center - A Multiple Energy Injection Model
We suggest that the energy source of the observed diffuse gamma-ray emission
from the direction of the Galactic center is the Galactic black hole Sgr A*,
which becomes active when a star is captured at a rate of
yr^{-1}. Subsequently the star is tidally disrupted and its matter is accreted
into the black hole. During the active phase relativistic protons with a
characteristic energy erg per capture are ejected. Over
90% of these relativistic protons disappear due to proton-proton collisions on
a timescale years in the small central bulge region with
radius pc within Sgr A*, where the density is cm^{-3}. The
gamma-ray intensity, which results from the decay of neutral pions produced by
proton-proton collisions, decreases according to , where t is
the time after last stellar capture. Less than 5% of relativistic protons
escaped from the central bulge region can survive and maintain their energy for
>10^7 years due to much lower gas density outside, where the gas density can
drop to cm. They can diffuse to a pc region before
disappearing due to proton-proton collisions. The observed diffuse GeV
gamma-rays resulting from the decay of neutral pions produced via collision
between these escaped protons and the gas in this region is expected to be
insensitive to time in the multi-injection model with the characteristic
injection rate of 10^{-5} yr^{-1}. Our model calculated GeV and 511 keV
gamma-ray intensities are consistent with the observed results of EGRET and
INTEGRAL, however, our calculated inflight annihilation rate cannot produce
sufficient intensity to explain the COMPTEL data.Comment: 8 pages, 3 figures, accepted by A&
X-ray and Radio Variability of M31*, The Andromeda Galaxy Nuclear Supermassive Black Hole
We confirm our earlier tentative detection of M31* in X-rays and measure its
light-curve and spectrum. Observations in 2004-2005 find M31* rather quiescent
in the X-ray and radio. However, X-ray observations in 2006-2007 and radio
observations in 2002 show M31* to be highly variable at times. A separate
variable X-ray source is found near P1, the brighter of the two optical nuclei.
The apparent angular Bondi radius of M31* is the largest of any black hole, and
large enough to be well resolved with Chandra. The diffuse emission within this
Bondi radius is found to have an X-ray temperature ~0.3 keV and density 0.1
cm-3, indistinguishable from the hot gas in the surrounding regions of the
bulge given the statistics allowed by the current observations. The X-ray
source at the location of M31* is consistent with a point source and a power
law spectrum with energy slope 0.9+/-0.2. Our identification of this X-ray
source with M31* is based solely on positional coincidence.Comment: 25 pages, 8 figures, submitted to Ap
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Efficiency of evolutionary algorithms in water network pipe sizing
The pipe sizing of water networks via evolutionary algorithms is of great interest because it allows the selection of alternative economical solutions that meet a set of design requirements. However, available evolutionary methods are numerous, and methodologies to compare the performance of these methods beyond obtaining a minimal solution for a given problem are currently lacking. A methodology to compare algorithms based on an efficiency rate (E) is presented here and applied to the pipe-sizing problem of four medium-sized benchmark networks (Hanoi, New York Tunnel, GoYang and R-9 Joao Pessoa). E numerically determines the performance of a given algorithm while also considering the quality of the obtained solution and the required computational effort. From the wide range of available evolutionary algorithms, four algorithms were selected to implement the methodology: a PseudoGenetic Algorithm (PGA), Particle Swarm Optimization (PSO), a Harmony Search and a modified Shuffled Frog Leaping Algorithm (SFLA). After more than 500,000 simulations, a statistical analysis was performed based on the specific parameters each algorithm requires to operate, and finally, E was analyzed for each network and algorithm. The efficiency measure indicated that PGA is the most efficient algorithm for problems of greater complexity and that HS is the most efficient algorithm for less complex problems. However, the main contribution of this work is that the proposed efficiency ratio provides a neutral strategy to compare optimization algorithms and may be useful in the future to select the most appropriate algorithm for different types of optimization problems
Standard Model Higgs boson production in association with a top anti-top pair at NLO with parton showering
We present predictions for the production cross section of a Standard Model
Higgs boson in association with a top-antitop pair at next-to-leading order
accuracy using matrix elements obtained from the HELAC-Oneloop package. The NLO
prediction was interfaced to the PYTHIA and HERWIG shower Monte Carlo programs
with the help of POWHEG-Box, allowing for decays of massive particles,
showering and hadronization, thus leading to final results at the hadron level.Comment: 14 pages, 9 figure
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