Digital Repository 2.0: Lessons Learned and Applied

This presentation discusses the University of North Texas (UNT) Libraries' Digital Projects Unit and how the system and software to create digital collections was developed. It also discusses the future plans for system and software changes in the Digital Projects Unit

Transport Neutral Digital Object Replication

Paper for the 2011 Society for Imaging Science and Technology (IS&T) Archiving Conference. This paper discusses a project by the University of North Texas (UNT) Libraries to implement a simple transport neutral digital object replication strategy in its production digital repository infrastructure

PREMIS Event Service

This paper discusses the PREMIS Event Service. The University of North Texas (UNT) Libraries have created a digital library infrastructure that is designed using the Curation Micro Services methodology for building repositories. Based on modular components designed for reuse and re-configuration the authors propose a general-purpose preservation event logging system using the PREMIS Event and Agent data model. An example implementation developed with the Django Web framework and employing RESTful design patterns with the Atom Publishing Protocol is described

PREMIS Event Service

This presentation discusses the PREMIS Event Service. The University of North Texas (UNT) Libraries has created a digital library infrastructure that is designed using the Curation Micro Services methodology for building repositories. Based on modular components designed for reuse and re-configuration the authors propose a general-purpose preservation event logging system using the PREMIS Event and Agent data model

Is the inflammasome a potential therapeutic target in renal disease?

The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cytoplasmic trigger inflammasome assembly. These receptors sense danger signals including damage-associated molecular patterns and pathogen-associated molecular patterns (DAMPS and PAMPS respectively). The best-characterized inflammasome is the NLRP3 inflammasome. On assembly of the NLRP3 inflammasome, post-translational processing and secretion of pro-inflammatory cytokines IL-1β and IL-18 occurs; in addition, cell death may be mediated via caspase-1. Intrinsic renal cells express components of the inflammasome pathway. This is most prominent in tubular epithelial cells and, to a lesser degree, in glomeruli. Several primary renal diseases and systemic diseases affecting the kidney are associated with NLRP3 inflammasome/IL-1β/IL-18 axis activation. Most of the disorders studied have been acute inflammatory diseases. The disease spectrum includes ureteric obstruction, ischaemia reperfusion injury, glomerulonephritis, sepsis, hypoxia, glycerol-induced renal failure, and crystal nephropathy. In addition to mediating renal disease, the IL-1/ IL-18 axis may also be responsible for development of CKD itself and its related complications, including vascular calcification and sepsis. Experimental models using genetic deletions and/or receptor antagonists/antiserum against the NLRP3 inflammasome pathway have shown decreased severity of disease. As such, the inflammasome is an attractive potential therapeutic target in a variety of renal diseases

CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Transport Neutral Digital Object Replication [Poster]

This poster discusses digital object replication. The University of North Texas (UNT) Libraries has implemented a simple transport neutral digital object replication strategy in its production digital repository infrastructure. This strategy is built with the same ideals as other Curation Micro-Services, in respect to lightweight, software independent specifications coupled to provide a set of services for digital repositories, this approach to replication has allowed the UNT Libraries the flexibility of multiple storage infrastructures and the reassurance the objects are being fully validated as they are replicated throughout the repository

An Integer-Valued Time Series Model for Hotels that Accounts for Constrained Capacity

Many service industry firms strive hard to fill free capacity in order to cover their costs for a fixed capital stock. This paper presents a time series model where the capacity constraint is an integral part. The integer-valued autoregressive model builds on a simple idea of how daily time series arise for hotels and other similar establishments. Measures that follow naturally from the time series model are the occupancy probability and the duration of stay for the visitor. Empirically, we study the effects of price changes and a large festival, on these measures.

The University of North Texas Libraries' Portal to Texas History: Archival Challenges and Solutions [Poster]

Poster presented at the 2004 Joint Conference on Digital Libraries (JCDL). This poster details the system that automates the collection of metadata records to coordinate access to web-viewable files and preservation of archived master files