The consolidation of implicit sequence memory in obstructive sleep apnea

Obstructive Sleep Apnea (OSA) Syndrome is a relatively frequent sleep disorder characterized by disrupted sleep patterns. It is a well-established fact that sleep has beneficial effect on memory consolidation by enhancing neural plasticity. Implicit sequence learning is a prominent component of skill learning. However, the formation and consolidation of this fundamental learning mechanism remains poorly understood in OSA. In the present study we examined the consolidation of different aspects of implicit sequence learning in patients with OSA. We used the Alternating Serial Reaction Time task to measure general skill learning and sequence-specific learning. There were two sessions: a learning phase and a testing phase, separated by a 10-hour offline period with sleep. Our data showed differences in offline changes of general skill learning between the OSA and control group. The control group demonstrated offline improvement from evening to morning, while the OSA group did not. In contrast, we did not observe differences between the groups in offline changes in sequence-specific learning. Our findings suggest that disrupted sleep in OSA differently affects neural circuits involved in the consolidation of sequence learning

Restauration de pâturages sahéliens par le travail du sol et constitution de collections vivantes d'écotypes fourragers : Rapport de mission en Haute-Volta, au Sénégal, Niger et Mali, 3 novembre - 13 décembre 1977

Objectif de la mission : choisir des sites, établir un programme d'essais des méthodes de traitement des sols, étudier le matériel afin d'améliorer le couvert des paturages naturels de Haute-Volta, du Sénégal, du Niger et du Mal