Advanced turbocharger design study program

The advanced Turbocharger Design Study consisted of: (1) the evaluation of three advanced engine designs to determine their turbocharging requirements, and of technologies applicable to advanced turbocharger designs; (2) trade-off studies to define a turbocharger conceptual design and select the engine with the most representative requirements for turbocharging; (3) the preparation of a turbocharger conceptual design for the Curtiss Wright RC2-32 engine selected in the trade-off studies; and (4) the assessment of market impact and the preparation of a technology demonstration plan for the advanced turbocharger

Will I? won't I? Why do men who have sex with men present for post-exposure prophylaxis for sexual exposures?

Background: Failures of post-exposure prophylaxis following sexual exposure (PEPSE) to prevent seroconversion have been reported and are often associated with ongoing risk exposure. Understanding why men who have sex with men (MSM) access PEPSE on some occasions and not others may lead to more effective health promotion and disease prevention strategies Methods: A qualitative study design using semi-structured interviews of 15 MSM within 6 months of them initiating PEPSE treatment at an HIV outpatient service in Brighton, UK. Results: PEPSE seeking was motivated by a number of factors: an episode that related to a particular sexual partner and their behaviour; the characteristics of the venue where the risk occurred; the respondent’s state of mind and influences of alcohol and recreational drug use; and their perceived beliefs on the effectiveness of PEPSE. Help was sought in the light of a “one-off” or “unusual” event. Many respondents felt they were less likely to behave in a risky manner following PEPSE. Conclusion: If PEPSE is to be effective as a public health measure, at risk individuals need to be empowered to make improved risk calculations from an increased perception that they could be exposed to HIV if they continue their current behaviour patterns. The concern is that PEPSE was sought by a low number of MSM implying that a greater number are not using the service based on failure to make accurate risk calculations or recognise high-risk scenario

Weekend hospitalization and additional risk of death: An analysis of inpatient data

Objective To assess whether weekend admissions to hospital and/or already being an inpatient on weekend days were associated with any additional mortality risk.Design Retrospective observational survivorship study. We analysed all admissions to the English National Health Service (NHS) during the financial year 2009/10, following up all patients for 30 days after admission and accounting for risk of death associated with diagnosis, co-morbidities, admission history, age, sex, ethnicity, deprivation, seasonality, day of admission and hospital trust, including day of death as a time dependent covariate. The principal analysis was based on time to in-hospital death.Participants National Health Service Hospitals in England.Main Outcome Measures 30 day mortality (in or out of hospital).Results There were 14,217,640 admissions included in the principal analysis, with 187,337 in-hospital deaths reported within 30 days of admission. Admission on weekend days was associated with a considerable increase in risk of subsequent death compared with admission on weekdays, hazard ratio for Sunday versus Wednesday 1.16 (95% CI 1.14 to 1.18; P < .0001), and for Saturday versus Wednesday 1.11 (95% CI 1.09 to 1.13; P < .0001). Hospital stays on weekend days were associated with a lower risk of death than midweek days, hazard ratio for being in hospital on Sunday versus Wednesday 0.92 (95% CI 0.91 to 0.94; P < .0001), and for Saturday versus Wednesday 0.95 (95% CI 0.93 to 0.96; P < .0001). Similar findings were observed on a smaller US data set.Conclusions Admission at the weekend is associated with increased risk of subsequent death within 30 days of admission. The likelihood of death actually occurring is less on a weekend day than on a mid-week day

Highly sensitive alkane odour sensors based on functionalised gold nanoparticles

We deposit dense, ordered, thin films of Au-dodecanethiol core/shell nanoparticles by the Langmuir-Schafer (LS) printing method, and find that their resistance at ambient temperature responds selectively and sensitively to alkane odours. Response is a rapid resistance increase due to swelling, and is strongest for alkane odours where the alkane chain is similar in length to the dodecane shell. For decane odours, we find a response to concentrations as low as 15 ppm, about 600 times below the lower explosive limit. Response is weaker, but still significant, to aromatic odours (e.g. Toluene, Xylene), while potential interferants such as polar and/or hydrogen-bonding odours (e.g. alcohols, ketones, water vapour) are somewhat rejected. Resistance is weakly dependent on temperature, and recovers rapidly and completely to its original value within the error margin of measurement. (C) 2011 Elsevier B.V. All rights reserved

Exploring the movement dynamics of deception

Both the science and the everyday practice of detecting a lie rest on the same assumption: hidden cognitive states that the liar would like to remain hidden nevertheless influence observable behavior. This assumption has good evidence. The insights of professional interrogators, anecdotal evidence, and body language textbooks have all built up a sizeable catalog of non-verbal cues that have been claimed to distinguish deceptive and truthful behavior. Typically, these cues are discrete, individual behaviors—a hand touching a mouth, the rise of a brow—that distinguish lies from truths solely in terms of their frequency or duration. Research to date has failed to establish any of these non-verbal cues as a reliable marker of deception. Here we argue that perhaps this is because simple tallies of behavior can miss out on the rich but subtle organization of behavior as it unfolds over time. Research in cognitive science from a dynamical systems perspective has shown that behavior is structured across multiple timescales, with more or less regularity and structure. Using tools that are sensitive to these dynamics, we analyzed body motion data from an experiment that put participants in a realistic situation of choosing, or not, to lie to an experimenter. Our analyses indicate that when being deceptive, continuous fluctuations of movement in the upper face, and somewhat in the arms, are characterized by dynamical properties of less stability, but greater complexity. For the upper face, these distinctions are present despite no apparent differences in the overall amount of movement between deception and truth. We suggest that these unique dynamical signatures of motion are indicative of both the cognitive demands inherent to deception and the need to respond adaptively in a social context

On the exactly solvable pairing models for bosons

We propose the new exactly solvable model for bosons corresponding to the attractive pairing interaction. Using the electrostatic analogy, the solution of this model in thermodynamic limit is found. The transition from the superfluid phase with the Bose condensate and the Bogoliubov - type spectrum of excitations in the weak coupling regime to the incompressible phase with the gap in the excitation spectrum in the strong coupling regime is observed.Comment: 19 page

A first appraisal of the landing and mechanism of the Santos fishery

This paper summarizes and analyses the landing data collected at Santos, Brazil, during the 12 months period, July 1958-June 1959. These data are given in terms of weight landed of the more important fish and shrimp and also in terms of value. The distribution of the landings of each of the more important species is shown both according to the type of fishing gear used and fishing area. The fishing area is given in the form of statistical rectangles of 60 miles square. The landings are broken down to obtain a figure for the landing per hour of fishing for each species, for each gear and for each rectangle fished. This figure of landing per unit fishing time is used to compare one area with another, one gear with another, and one month with another for each of the important species. In this way, comparisons of the available density of a species by time, area and fishing gear are made.Êste trabalho sintetiza e analisa os dados coletados em Santos, Brasil, sobre o desembarque de pescado durante o período de 12 meses, de julho de 1958 a junho de 1959. Estes dados são apresentados em termos de peso desembarcado, para as espécies de peixes mais importantes e camarões e, também, em termos de valor econômico. A distribuição dos desembarques de cada uma das espécies mais importantes é apresentada tanto em relação ao tipo de aparelho de pesca usado, como em relação à área de pesca. Essa área é dada sob forma de retângulos estatísticos de 60 milhas quadradas. Os desembarques são classificados para se obter o valor do desembarque por hora de pesca para cada espécie, para cada aparelho e para cada retângulo pescado. Este valor do desembarque por unidade de tempo de captura é usado para comparar as áreas entre si, os aparelhos de captura entre si e os meses do ano entre si, em relação a cada espécie importante. Deste modo são feitas as comparações da densidade disponível de uma espécie no tempo, na área de pesca e por aparelho de pesca

Museum DNA reveals the demographic history of the endangered Seychelles warbler

The importance of evolutionary conservation – how understanding evolutionary forces can help guide conservation decisions – is widely recognized. However, the historical demography of many endangered species is unknown, despite the fact that this can have important implications for contemporary ecological processes and for extinction risk. Here, we reconstruct the population history of the Seychelles warbler (Acrocephalus sechellensis) – an ecological model species. By the 1960s, this species was on the brink of extinction, but its previous history is unknown. We used DNA samples from contemporary and museum specimens spanning 140 years to reconstruct bottleneck history. We found a 25% reduction in genetic diversity between museum and contemporary populations, and strong genetic structure. Simulations indicate that the Seychelles warbler was bottlenecked from a large population, with an ancestral Ne of several thousands falling to <50 within the last century. Such a rapid decline, due to anthropogenic factors, has important implications for extinction risk in the Seychelles warbler, and our results will inform conservation practices. Reconstructing the population history of this species also allows us to better understand patterns of genetic diversity, inbreeding and promiscuity in the contemporary populations. Our approaches can be applied across species to test ecological hypotheses and inform conservation

A Five-year Spectroscopic and Photometric Campaign on the Prototypical alpha Cygni Variable and A-type Supergiant Star Deneb

Deneb is often considered the prototypical A-type supergiant, and is one of the visually most luminous stars in the Galaxy. A-type supergiants are potential extragalactic distance indicators, but the variability of these stars needs to be better characterized before this technique can be considered reliable. We analyzed 339 high resolution echelle spectra of Deneb obtained over the five-year span of 1997 through 2001 as well as 370 Stromgren photometric measurements obtained during the same time frame. Our spectroscopic analysis included dynamical spectra of the H-alpha profile, H-alpha equivalent widths, and radial velocities measured from Si II 6347, 6371. Time-series analysis reveals no obvious cyclic behavior that proceeds through multiple observing seasons, although we found a suspected 40 day period in two, non-consecutive observing seasons. Some correlations are found between photometric and radial velocity data sets, and suggest radial pulsations at two epochs. No correlation is found between the variability of the H-alpha profiles and that of the radial velocities or the photometry. Lucy (1976) found evidence that Deneb was a long period single-lined spectroscopic binary star, but our data set shows no evidence for radial velocity variations caused by a binary companion.Comment: 49 pages, 9 figures, 5 tables, accepted for publication in the Astronomical Journa

Particle Impact Analysis of Bulk Powder During Pneumatic Conveyance

Fragmentation of powders during transportation is a common problem for manufacturers of food and pharmaceutical products. We illustrate that the primary cause of breakage is due to inter-particle collisions, rather than particle-wall impacts, and provide a statistical mechanics model giving the number of collisions resulting in fragmentation