50 research outputs found

    Assessment of the reforms and programs results of Ukraine’s economy sustainable development by means of neural networks

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    It is necessary to choose proper methodology and indicators for assessing sustainable economic development as the information becomes a tool for decision-making support of sustainable development policies and implementation of programs. In Ukraine, evaluating the results of implementation of different programs for development is essential as an analytical basis for making a strategy for the next period and a prerequisite for further progress. Certain shortcomings of linear models for evaluating the results appeared during the design and implementation of the strategy to manage sustainable economic development. The potential for establishing erroneous targets increases in the formation of strategic objectives for the next forecast period. There is a special need to choose adequate indicators to comprehensively approximate the factors of economic development and evaluation methods that allow more sensitively measuring the results of management decisions in the implementation of the strategy. The article evaluates the results of the Sustainable Development Strategy “Ukraine – 2020”, employing the potential of the neural network method for a flexible combination of a large number of factors in constructing nonlinear models of impact on the resulting indicator. As a result of applying the neural network model with one hidden layer for evaluation, based on 16 indicators identifying economic, social, and institutional aspects of sustainable development of Ukraine, it was found that institutional transformations contribute most to achieving sustainable development. Reforms in terms of deregulation and support of entrepreneurship, property rights protection, and competitive environment have the most significant positive impact. On the other hand, low efficiency of capital market reforms, implementation of the energy efficiency program, and reform in the field of public procurement determine the need to revise the program of their fulfilment

    Containing of Biomaterials Based on Chitosan and Argenium (I) Nitrate

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    Великий інтерес до хітину та хітозану пов’язана з їх унікальними фізіологічними і екологічними властивостями, такими як біосумісність, біодеструкція, фізіологічна активність, та інші. У статті продемонстрована можливість отримати біоматеріал хітозан з антарктичного криля. Для цього була поставлена задача по відпрацюванні технології 52 ISSN 2415-8526. Prirodničì nauki – 2018. Issue 15 виділення хітину із первинної сировини. Були досліджені фізико-хімічні показники якості хітозану, виділеного з панциру антарктичного криля. На основі проведених аналізів і зрівняннь властивостей зразків встановлено, що наш біоматеріал йодид хітозану з арґентум (І) нітратом близький до хітозану.Great interest in chitin and chitosan is due to their unique physiological and environmental properties, such as biocompatibility, biodestruction, physiological activity, and others. The article demonstrates the possibility of obtaining chitosan biomaterial from Antarctic krill. To this end, the task was set for the development of technology for the obtaining of chitin from primary raw materials. Physicochemical parameters of the quality of chitosan obtained from the Antarctic krill armor were studied. Based on the analysis performed and comparison of the properties of the samples, it was established that our biomaterial, chitosan iodide with silver (I) nitrate, is close to chitosan

    Studying the physical-chemical properties of alloyed metallurgical waste as secondary resource-saving raw materials

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    Дослiджено особливостi фазового складу та мiкроструктури шлакiв алюмотермiчного виробництва лiгатур тугоплавких елементiв рiзних марок та окалини швидкорiжучої сталi Р6М5 щодо природи присутностi легуючих елементiв. Це необхiдно для забезпечення зменшення втрат Mo, W та iнших легуючих елементiв сублiмацiєю з пiдвищенням температури при переробцi техногенних вiдходiв. Фазовий склад визначали методом рентгенофазового аналiзу. Мiкроструктуру дослiджували на растровому електронному мiкроскопi в комплексi з рентгенiвським мiкроаналiзом використанням безеталоного методу розрахунку фундаментальних параметрiв. Визначено, що шлаки алюмотермiчного виробництва лiгатур АХМ-50 та АМВТ складаються з CaAl4O7 та з’єднань AlV2O4 i CrO2. Це може обумовлювати певний рiвень легованостi шлаку тугоплавкими елементами. У шлаку вiд виплавки лiгатури МФТА виявлено фази Al75Mo20W5 та Mo(Si, Al)3, що можуть бути представленi металевими вкрапленнями. Фази окалини сталi Р6М5 в основному представленi Fe3O4, Fe2O3 та FeO. Також виявлено FeWO4, MoO2, WC, Mo2C, що обумовлюється пiдвищеним ступенем легованостi W та Mo. Не виключено, що деяка частка атомiв легуючих елементiв, в тому числi Cr та V, може знаходитися в якостi атомiв замiщення в оксидах Fe. Мiкроструктура дослiджених шлакiв та окалини характеризувалася розупорядкованiстю часток рiзного розмiру та форми. Виявлено присутнiсть в окалинi часток з вiдносно високим вмiстом легуючих елементiв. В дослiджених матерiалах вiдсутнi з’єднання з пiдвищеною схильнiстю до сублiмацiї. Це зумовлює вiдносно високий ступiнь використання легуючих елементiв. В дослiджених матерiалах вiдсутнi з’єднання з пiдвищеною схильнiстю до сублiмацiї. Це зумовлює вiдносно високий ступiнь використання легуючих елементiв i зменшує певнi обмеження додавання дослiджених шлакiв у шлакоутворюючi сумiшi та температурнi обмеження режимiв плавлення. Використання шлакiв алюмотермiчгого виробництва та окалини швидкорiжучих сталей в шихтi для виплавки легуючого сплаву забезпечило вилучення тугоплавких елементiв та додаткову легованiсть кiнцевого продукт

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

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    © 2024 The Authors. Journal of Extracellular Vesicles, published by Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly.Peer reviewe

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

    Get PDF
    Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional studies. To address the challenges and opportunities in this rapidly evolving field, the International Society for Extracellular Vesicles (ISEV) updates its 'Minimal Information for Studies of Extracellular Vesicles', which was first published in 2014 and then in 2018 as MISEV2014 and MISEV2018, respectively. The goal of the current document, MISEV2023, is to provide researchers with an updated snapshot of available approaches and their advantages and limitations for production, separation and characterisation of EVs from multiple sources, including cell culture, body fluids and solid tissues. In addition to presenting the latest state of the art in basic principles of EV research, this document also covers advanced techniques and approaches that are currently expanding the boundaries of the field. MISEV2023 also includes new sections on EV release and uptake and a brief discussion of in vivo approaches to study EVs. Compiling feedback from ISEV expert task forces and more than 1000 researchers, this document conveys the current state of EV research to facilitate robust scientific discoveries and move the field forward even more rapidly

    Über die klinische Stellung der Paraphrenien

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    Technonationalist Trends in the Development of Global Actors of Military Innovation

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    The article is devoted to the study of the theory and practice of one of the schools of management of national competitiveness – techno-nationalism. The aim of the study is to identify the features of the development of modern techno-nationalism, the practices of managing national competitiveness in the defense industry sector of the countries of the world technological core, and to identify potential threats to the impact of the implementation of such a policy on the global and national security of other countries. The specific characteristics of modern technologies associated with dual-use are considered. The rating position of the leading countries in terms of technologies by sectors of the economy has been investigated, with the definition of the features of techno-nationalist policies of European and Asian countries. The fundamental ideological differences between the two systems are indicated. The current innovative technology trends associated with dual-use technologies in the United States and China have been identified. The increasing influence of the American government on other markets for the latest technologies in the countries of the world has been proven. The guidelines of Beijing's techno-national policy towards new quantum computing (QC) are considered, which determines not only an increase in the country's military-technological potential but also possible future challenges on a global and regional scale. The technological trends in the development of innovative technologies that cause concern of the world community and can be the basis for the formation of national and global risks and threats to security have been identified

    Zum wesen der hysterie

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