Flow analysis from multiparticle azimuthal correlations

We present a new method for analyzing directed and elliptic flow in heavy ion collisions. Unlike standard methods, it separates the contribution of flow to azimuthal correlations from contributions due to other effects. The separation relies on a cumulant expansion of multiparticle azimuthal correlations, and includes corrections for detector inefficiencies. This new method allows the measurement of the flow of identified particles in narrow phase-space regions, and can be used in every regime, from intermediate to ultrarelativistic energies.Comment: 31 pages, revtex. Published version (references added

Theory of Sound Propagation in Superfluid Solutions Filled Porous Media

A theory of the propagation of acoustic waves in a porous medium filled with superfluid solution is developed. The elastic coefficients in the system of equations are expressed in terms of physically measurable quantities. The equations obtained describe all volume modes that can propagate in a porous medium saturated with superfluid solution. Finally, derived equations are applied to the most important particular case when the normal fluid component is locked inside a highly porous media (aerogel) by viscous forces and the velocities of two longitudinal sound modes are calculated.Comment: 13 pages, 0 figure

Vilnius Declaration on chronic respiratory diseases : multisectoral care pathways embedding guided self-management, mHealth and air pollution in chronic respiratory diseases

Correction: Volume: 10 Issue: 1 Article Number: 49 DOI: 10.1186/s13601-020-00357-4 Published: DEC 17 2020Background: Over 1 billion people suffer from chronic respiratory diseases such as asthma, COPD, rhinitis and rhinosinusitis. They cause an enormous burden and are considered as major non-communicable diseases. Many patients are still uncontrolled and the cost of inaction is unacceptable. A meeting was held in Vilnius, Lithuania (March 23, 2018) under the patronage of the Ministry of Health and several scientific societies to propose multisectoral care pathways embedding guided self-management, mHealth and air pollution in selected chronic respiratory diseases (rhinitis, chronic rhinosinusitis, asthma and COPD). The meeting resulted in the Vilnius Declaration that was developed by the participants of the EU Summit on chronic respiratory diseases under the leadership of Euforea. Conclusion: The Vilnius Declaration represents an important step for the fight against air pollution in chronic respiratory diseases globally and has a clear strategic relevance with regard to the EU Health Strategy as it will bring added value to the existing public health knowledge.Peer reviewe

The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database

Funding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe

Surveys on grapevine yellows incidence on Georgian grapevine varieties

INTRODUCTION \u2013 Grapevine yellows (GY) are a phytoplasma-associated disease complex that induces severe crop losses in almost all varieties used for wine production in the Euro-Mediterranean area and in other continents. Typical GY symptoms include berry shrivel, desiccation of inflorescences, color alterations and curling of the leaves, reduction of growth, and irregular ripening of wood. Chemical treatments against insect vectors of GY-associated phytoplasmas are essential to contain the disease spreading. A strategy for phytoplasma disease control is based on the selection of resistant, tolerant or not susceptible plant varieties. Unfortunately, up to now none of the examined Vitis species and V. vinifera varieties have been found immune or resistant to the phytoplasma associated with GYs. AIMS AND SCOPES \u2013 The main objective of this study was to verify the presence of GY diseases in collections of Georgian autochthon grapevine varieties and to investigate the spreading of phytoplasma diseases in vineyards. MATERIALS AND METHODS \u2013 Three collections representing the autochthon Georgian germplasm, located in Saguramo (Shida Kartli), Shumi and Kindzmarauli (Kakheti province), were visited in order to looking for the presence of typical GY symptoms, clearly visible in September. Moreover, three Georgian vineyard areas [one in Mukhrani (Shida Kartli) and two in Khondoli (Kakheti)], in which both international and local varieties were cultivated, were also surveyed for GY disease. RESULTS AND DISCUSSIONS \u2013 In Saguramo and Shumi, in most cases, grapevines were symptomless. GY symptoms were observed only in plants of the varieties Mtredisphekha and Adznizhi in Saguramo, and in plants of the varieties Saperavi Pachkha and Grdzelmtevana in Shumi. In the collection of Kindzmarauli, GY symptoms were observed in 18 varieties among which Saperavi, Goruli Mtsvane, Khikhvi and Kisi are more cultivated in Georgia. In Mukhrani, GY largely affected Chardonnay and, with lower incidence, Muscat Blanc, while no evident symptoms were reported on white autochthon varieties (Rkatsiteli and Goruli Mtsvane). On the other hand, plants of the red local variety Saperavi showed GY symptoms. Interestingly, Convolvulus arvensis, widely reported as host plant of phytoplasmas associated with 'bois noir' (one of the diseases of GY complex) and of its insect vector Hyalesthes obsoletus, was largely covering the ground of these vineyards (both international and local varieties) in Mukhrani. Moreover, some plants of C. arvensis showed symptoms (yellowing, reddening, dwarfism, leaf malformation) related to infection by phytoplasmas. In Kakheti region, typical GY symptoms were observed not only on numerous plants of Chardonnay, but also on few plants of local varieties Rkatsiteli, Kisi, Saperavi and Mtsvane Kakhuri. In this region, the presence of C. arvensis was considerably lower than in Mukhrani, and the more spread weed was Artemisia vulgaris, recently reported in literature as host plant of the 'bois noir' phytoplasma vector H. obsoletus. CONCLUSIONS AND POSSIBLE APPLICATIONS \u2013 Further molecular analyses will be carried out to identify the phytoplasmas infecting grapevines in Georgia. This aspect is crucial for understanding the GY epidemiology and the application of strategies for disease containment. Evidences from this study highlighted that GY are present in Georgia, as showed by numerous diseased plants of international varieties (mainly Chardonnay). Intriguingly, the fact that some local autochthon varieties are symptomless in areas where GY strongly affects Chardonnay constitutes a preliminary indication that such Georgian varieties could be tolerant or resistant to phytoplasmas

New 'Candidatus Phytoplasma solani' strains associated with Bois noir disease in Vitis vinifera L. cultivars in Georgia

Preliminary survey highlighted that bois noir (BN) disease, associated with 'Candidatus Phytoplasma (\u2018Ca. P.\u2019) solani', affects grapevine varieties in Georgia (South Caucasus). In this study, further research was carried out to investigate the BN symptom severity in international and Georgian native varieties. Identification and characterization of 'Ca. P. solani' was performed by analysis of 16S rDNA, vmp1 and stamp gene nucleotide sequences. During field surveys, moderate/mild and severe symptoms were observed on Georgian grapevine varieties and international cultivars, respectively. Molecular characterization of 'Ca. P. solani' identified in grapevines revealed the presence of 11 genetically distinct phytoplasma types. Ten of such 'Ca. P. solani' types were described here for the first time; only one type (VmGe12/StGe7) was identical to a strain previously reported in periwinkle in Lebanon. Phylogenetic analyses of vmp1 and stamp gene concatenated nucleotide sequences indicated that 'Ca. P. solani' strains in Georgia are associated mainly with the bindweed-related BN host system. Moreover, the presence of the same 'Ca. P. solani' strains in grapevine cultivars showing a range of symptom intensity suggested a different susceptibility of Georgian local varieties to BN

New Byzantine Seals from Medieval Sugdaia

Поступила в редакцию 20.06.2019. Принята к печати 11.11.2019.Submitted: 20.06.2019. Accepted: 11.11.2019.The work introduces into scientific circulation five Byzantine seals originating from the excavations of recent years in Sudak of the South-Eastern Crimean expedition of the state Hermitage. 1. Private seal of Epiphany Kamateros (late eleventh century) is known to us Imperial functionary, known from other monuments sphragistics. It seems that the discovery of the seal of Epiphany is another evidence that the representatives of the noble Byzantine families sent their correspondence to their possessions in the Crimea. 2. Seal of the Leon, the imperial spatharocandidatos and stratigos of Cherson (mid ninth century) pointed out the close relationship Sugdaia and Chersonesos at this time. 3. Seal unknown by name, the imperial protospatharios and logothetes of genicon (ninth–tenth century) is another indication that Sugdaia levied Imperial taxes. 4–5. Two seals poor state of preservation. According to the invocative monograms can be dated eighth–ninth centuries.Работа вводит в научный оборот пять византийских печатей, происходящих из археологических работ последних лет Юго-Восточной Крымской экспедиции Государственного Эрмитажа в Судаке. Частная печать Епифания Каматира (конец XI в.), известного имперского функционера. Можно полагать, что находка печати Епифания является еще одним свидетельством того, что представители знатных византийских родов отправляли свою корреспонденцию в свои владения в Крыму. Печать Льва, императорского протоспафария и стратига Херсона (середина IX в.), указывает на тесную связь Сугдеи и Херсона в это время. Печать неизвестного по имени имперского протоспафария и логофета геникона (IX–X вв.) является еще одним свидетельством того, что в Сугдее взимались имперские налоги. Две печати плохой сохранности по инвокативным монограммам можно датировать VIII–IX вв