Reuse patterns in adaptation languages : creating a meta-level for the LAG adaptation language

A growing body of research targets authoring of content and adaptation strategies for adaptive systems. The driving force behind it is semantics-based reuse: the same strategy can be used for various domains, and vice versa. Whilst using an adaptation language (LAG e.g.) to express reusable adaptation strategies, we noticed, however, that: a) the created strategies have common patterns that, themselves, could be reused; b) templates based on these patterns could reduce the designers' work; c) there is a strong preference towards XML-based processing and interfacing. This has leaded us to define a new meta-language for LAG, extracting common design patterns. This paper provides more insight into some of the limitations of Adaptation Languages like LAG, as well as describes our meta-language, and shows how introducing the meta-level can overcome some redundancy issues

Development and validation of Triticum phytobiological method as an alternative procedure for investigating in vivo acute toxicity on mice

The goal of this study was to validate an alternative method for determining in vivo acute toxicity using vegetal material instead of laboratory animals, starting from the phytobiological method known also as the Triticum technique. We set out to demonstrate that vegetal cells have similar sensitivity to some toxic agents as animal cells, in which case a statistical correlation could be established. A series of new compounds synthesized by the Romanian National Institute for Chemical Pharmaceutical Research and Development as potential β3 adrenergic receptors agonists were tested for their acute toxicity using classic animal exposure models, before investigating possible anti-diabetic and anti-obesity effects. We then determined whether similar conclusions might be reached exposing vegetal material to the same agents. We successfully demonstrated that plants are affected in a very similar way as animals when exposed to some potentially toxic agents, providing new possibilities for ending unethical animal experiments

Meta-scheduling Issues in Interoperable HPCs, Grids and Clouds

Over the last years, interoperability among resources has been emerged as one of the most challenging research topics. However, the commonality of the complexity of the architectures (e.g., heterogeneity) and the targets that each computational paradigm including HPC, grids and clouds aims to achieve (e.g., flexibility) remain the same. This is to efficiently orchestrate resources in a distributed computing fashion by bridging the gap among local and remote participants. Initially, this is closely related with the scheduling concept which is one of the most important issues for designing a cooperative resource management system, especially in large scale settings such as in grids and clouds. Within this context, meta-scheduling offers additional functionalities in the area of interoperable resource management, this is because of its great agility to handle sudden variations and dynamic situations in user demands. Accordingly, the case of inter-infrastructures, including InterCloud, entitle that the decentralised meta-scheduling scheme overcome issues like consolidated administration management, bottleneck and local information exposition. In this work, we detail the fundamental issues for developing an effective interoperable meta-scheduler for e-infrastructures in general and InterCloud in particular. Finally, we describe a simulation and experimental configuration based on real grid workload traces to demonstrate the interoperable setting as well as provide experimental results as part of a strategic plan for integrating future meta-schedulers

On the number of solutions of a transcendental equation arising in the theory of gravitational lensing

The equation in the title describes the number of bright images of a point source under lensing by an elliptic object with isothermal density. We prove that this equation has at most 6 solutions. Any number of solutions from 1 to 6 can actually occur.Comment: 26 pages, 12 figure

Analysis of power consumption in heterogeneous virtual machine environments

Reduction of energy consumption in Cloud computing datacenters today is a hot a research topic, as these consume large amounts of energy. Furthermore, most of the energy is used inefficiently because of the improper usage of computational resources such as CPU, storage and network. A good balance between the computing resources and performed workload is mandatory. In the context of data-intensive applications, a significant portion of energy is consumed just to keep alive virtual machines or to move data around without performing useful computation. Moreover, heterogeneity of resources increases the difficulty degree, when trying to achieve energy efficiency. Power consumption optimization requires identification of those inefficiencies in the underlying system and applications. Based on the relation between server load and energy consumption, we study the efficiency of data-intensive applications, and the penalties, in terms of power consumption, that are introduced by different degrees of heterogeneity of the virtual machines characteristics in a cluster

Analysis of power consumption in heterogeneous virtual machine environments

Reduction of energy consumption in Cloud computing datacenters today is a hot a research topic, as these consume large amounts of energy. Furthermore, most of the energy is used inefficiently because of the improper usage of computational resources such as CPU, storage and network. A good balance between the computing resources and performed workload is mandatory. In the context of data-intensive applications, a significant portion of energy is consumed just to keep alive virtual machines or to move data around without performing useful computation. Moreover, heterogeneity of resources increases the difficulty degree, when trying to achieve energy efficiency. Power consumption optimization requires identification of those inefficiencies in the underlying system and applications. Based on the relation between server load and energy consumption, we study the efficiency of data-intensive applications, and the penalties, in terms of power consumption, that are introduced by different degrees of heterogeneity of the virtual machines characteristics in a cluster

Assessing the Factorial Validity of the Attitudes and Belief Scale 2-Abbreviated Version: A Call for the Development a Gold Standard Method of Measuring Rational and Irrational Beliefs

Rational Emotive Behaviour Therapy (REBT) does not possess a measure of rational and irrational beliefs that meets internationally recognised standards for acceptable psychometric properties. Without such a measure the theory/practice of REBT cannot be rigorously evaluated, thus undermining its scientific veracity. The current study investigates the validity and reliability of a recently developed measure of rational and irrational beliefs: the Attitudes and Belief Scale 2-Abbreviated Version (ABS-2-AV). University students from three countries completed the ABS-2-AV (N = 397). An alternative models framework using confirmatory factor analysis indicated that a theoretically consistent eight-factor model of the ABS-2-AV provided the best fit of the data. A number of post-hoc modifications were required in order to achieve acceptable model fit results, and these modifications revealed important methodological limitations with the ABS-2-AV. Results indicated that the validity of the ABS-2-AV was undermined due to items measuring both the psychological process of interest (rational and irrational beliefs) and the context in which these beliefs processes are presented. This is a serious methodological limitation of the ABS-2 and all questionnaires derived from it, including the ABS-2-AV. This methodological limitation resulted in the ABS-2-AV possessing poor internal reliability. These limitations are discussed in relation to the broader REBT literature and the impact such problems have on research and practice. A call is made for REBT researchers to come together to develop a “gold standard” method of assessing rational and irrational beliefs that meets international standard for psychometric excellence

STUDY OF CORRELATIONS BY GROUPS OF CHARACTERS FOR SEED PRODUCTION IN BIRDSFOOT TREFOIL (LOTUS CORNICULATUS L.)

As for seed productions it was established that it is influenced by some characteristics which have a positive or negative influence. This, the direct correlations between seed yield, and the following characters is distinguished: number of inflorescences, number of pods, number of seed/pod, rate of seed setting. Dehiscence of the pods acts indirectly on the seed yield. Though the seed yield of birdsfoot trefoil is very much negatively influenced by the high degree of dehiscence in the pods, the studies pointed out an indirect, significant correlation between the dehiscence and the erect position of the shoots. As in majority of studied cases the sense and intensity of the correlations were similar for two seeding years it could by concluded that the relationships between the characters studied are genetically conditioned

Rapid assembly of customized TALENs into multiple

Transcriptional activator-like effector nucleases (TALENs) have become a powerful tool for genome editing. Here we present an efficient TALEN assembly approach in which TALENs are assembled by direct Golden Gate ligation into Gateway® Entry vectors from a repeat variable di-residue (RVD) plasmid array. We constructed TALEN pairs targeted to mouse Ddx3 subfamily genes, and demonstrated that our modified TALEN assembly approach efficiently generates accurate TALEN moieties that effectively introduce mutations into target genes. We generated "user friendly" TALEN Entry vectors containing TALEN expression cassettes with fluorescent reporter genes that can be efficiently transferred via Gateway (LR) recombination into different delivery systems. We demonstrated that the TALEN Entry vectors can be easily transferred to an adenoviral delivery system to expand application to cells that are difficult to transfect. Since TALENs work in pairs, we also generated a TALEN Entry vector set that combines a TALEN pair into one PiggyBac transposon-based destination vector. The approach described here can also be modified for construction of TALE transcriptional activators, repressors or other functional domains. © 2013 Zhang et al

Antioxidant activity in selected tomato genotypes cultivated in conventional and organic culture systems

The present study is a compilation of results obtained at the Vegetable Research and Development Station Bacau regarding the influence of the culture system on the quantitative and qualitative yield of tomatoes. The present study provides comparative information regarding yield achievements of tomato genotypes cultivated in two different culture systems (conventional and organic), in order to highlight the suitability of the cultivation system. The best yield results were obtained at a density of 30,000 plants per hectare in both culture systems. All studied genotypes resulted in quantitatively superior yield in the conventional system as opposed to the organic system. Another purpose of this study was to determine the difference in antioxidant activity of tomato genotypes cultivated in the ecological and the conventional culture systems. The results indicate the suitability of the tomato to organic cultivation, highlighting the potential of the tomato species to be utilized as a significant source of natural antioxidants, and also the influence of cultivation systems on the accumulation of antioxidant compounds.Keywords: Lycopersicon esculentum, polyphenols, flavones, yieldAfrican Journal of Biotechnology Vol. 12(20), pp. 2884-289