Balancing and scheduling tasks in assembly lines with sequence-dependent setup times

The classical Simple Assembly Line Balancing Problem (SALBP) has been widely enriched over the past few years with many realistic approaches and much effort has been made to reduce the distance between the academic theory and the industrial reality. Despite this effort, the scheduling of the execution of tasks assigned to every workstation following the balancing of the assembly line has been scarcely reported in the scientific literature. This is supposed to be an operational concern that the worker should solve himself, but in several real environments, setups between tasks exist and optimal or near-optimal tasks schedules should be provided inside each workstation. The problem presented in this paper adds sequence-dependent setup time considerations to the classical SALBP in the following way: whenever a task is assigned next to another at the same workstation, a setup time must be added to compute the global workstation time. After formulating a mathematical model for this innovative problem and showing the high combinatorial nature of the problem, eight different heuristic rules and a GRASP algorithm are designed and tested for solving the problem in reasonable computational time.Peer Reviewe

Decoherence from dipolar interspin interactions in molecular spin qubits

The realization of spin-based logical gates crucially depends on magnetically coupled spin qubits. Thus, understanding decoherence when spin qubits are in close proximity will become a roadblock to overcome. Herein, we propose a method free of fitting parameters to evaluate the qubit phase memory time Tm in samples with high electron spin concentrations. The method is based on a model aimed to estimate magnetic nuclear decoherence [P. C. E. Stamp and I. S. Tupitsyn, Phys. Rev. B 69, 014401 (2004)]. It is applied to a ground-spin J=8 magnetic molecule 1 displaying atomic clock transitions, namely [HoIII(W5O18)2]9−, which remarkably increase Tm at unusually high electron-spin concentrations. Our approach unveils the causes that limit the coherence reached at the clock transitions in challenging systems such as 1, where recent models fail

Development of type 2 diabetes mellitus thirty-one years after Billroth II in a patient asking for diabetes surgery

Introduction: Diabetes surgery in obese and slim patients seems to be a superior alternative to the current medical treatment. Gastric bypass is an alternative treat- ment for diabetes. Nevertheless, there are still doubts whether diabetes can recur if you gain weight or if the effects are maintained over time. Other questions refer to the type of surgery to make the bypass limb length or reservoir size for the resolution of the Diabetes Mellitus. Presentation of case: Male patient 69-year-old came to us in order to perform tailored One Anastomosis Gastric Bypass (BAGUA) to treat his type 2 diabetes mellitus and metabolic syndrome. He has a history of peptic ulcer treated with subtotal gastrectomy and Billroth II recons- truction 49 years ago. He currently is not obese and deve- loped diabetes 31 years after surgery. Discussion: Globally there are no reports of patients with normal BMI that after performing gastric bypass developed diabetes mellitus. There are cases where obese diabetic patients after gastric bypass improve or remits the T2DM, but it relapses due to insufficient weight loss or gain it. The patient with gastric bypass Billroth II type, should not developed diabetes. He is normal weight and not had weight gain that could be linked to the develop- ment of diabetes. Conclusions: The results generated by bariatric surgery are encouraging, but still do not clarify the precise way how surgery produces rapid improvement of systemic metabolism as in diabetes, but in our patient, the effect was quite different because the gastric bypass had no protective effect against diabetes

A Public Fabric Database for Defect Detection Methods and Results

[EN] The use of image processing for the detection and classification of defects has been a reality for some time in science and industry. New methods are continually being presented to improve every aspect of this process. However, these new approaches are applied to a small, private collection of images, which makes a real comparative study of these methods very difficult. The objective of this paper was to compile a public annotated benchmark, that is, an extensive set of images with and without defects, and make these public, to enable the direct comparison of detection and classification methods. Moreover, different methods are reviewed and one of these is applied to the set of images; the results of which are also presented in this paper.The authors thank for the financial support provided by IVACE (Institut Valencia de Competitivitat Empresarial, Spain) and FEDER (Fondo Europeo de Desarrollo Regional, Europe), throughout the projects: AUTOVIMOTION and INTELITEX.Silvestre-Blanes, J.; Albero Albero, T.; Miralles, I.; Pérez-Llorens, R.; Moreno, J. (2019). A Public Fabric Database for Defect Detection Methods and Results. AUTEX Research Journal. 19(4):363-374. https://doi.org/10.2478/aut-2019-0035S36337419

Portraiture in Early–Childhood education: a didactic proposal about art

El trabajo hace una propuesta didáctica destinada a la etapa de Educación Infantil, en la que se toma como base el género artístico del retrato. El estudio destaca la gran importancia que tiene la educación artística, en sus dos ámbitos —el crítico y el creativo— en la educación de los más pequeños, así como la gran utilidad del género del retrato, que se adapta perfectamente al objetivo de una enseñanza integral en la que los alumnos aprendan desde un punto de vista lúdico y creativo.The work makes a didactic proposal for the Early Childhood Education, based on the artistic genre of portraiture. He study highlights the great importance of the artistic education in its two senses —critical and creative— inside the early childhood education, and moreover the important utility of portraiture adapted properly to the target of an integrated education where students learn with a playful and creative point of view

A comparison of Clinical Risk Index for babies (CRIB-II), Score for Neonatal Acute Physiology (SNAP-II) and SNAPPE-II in predicting parenteral nutrition necessity in low birth weight preterm neonates.

Advances in perinatal care have made it possible to improve survival of low birth weight neonates. Clinical risk index for babies (CRIB-II), score for neonatal acute physiology (SNAP-II), and SNAP-perinatal extension-II (SNAPPE-II) have been used as mortality predictors for preterm infants. Feeding intolerance is very frequent in preterm neonates, and the development of an early effective biomarker for its prediction could be useful for carrying out a proper feeding strategy. Our aim was to compare the ability of CRIB-II, SNAP-II and SNAPPE-II in predict the feeding intolerance and parenteral nutrition necessity in preterm neonates. Methods: A retrospective cohort study on preterm neonates’ born at Jaen Hospital Complex with low birth weight and ≤ 36 weeks of gestation was done. Epidemiological, clinical and clinical scores CRIB II, SNAP-II and SNAPPE-II were recorded. Results: 255 low birth weight preterm neonates, 131 males (51.4%), aged ≤32 weeks of gestation (71%), were enrolled at our hospital. Parenteral nutrition needed were significantly higher in preterm neonates weighed 2500-1500 g (73.3%) and ≤ 1000g (87%). CRIB-II, SNAP-II and SNAPPE-II mean values were higher in neonates group subjected to parenteral nutrition compared with oral nutrition (p<0.05). CRIB-II and SNAPPE-II scores significantly correlated with parenteral nutrition days (p<0.05). Overall mortality rate was 11%. The 78.6% of all deceased infants needed parenteral nutrition. Conclusion: Clinical Risk Index for babies (CRIB-II) better than SNAPPE-II correlated with the feeding intolerance and thus the parenteral nutrition days in preterm neonates with low birth weight.Subvencionado: Ayuda del Plan Propio de Investigación de la UMA. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Reliability of a Field-Based Test for Hamstrings and Quadriceps Strength Assessment in Football Players

Background: Field-based tests using portable devices are extremely helpful to assist physicians and coaches in the assessment of athletes’ muscle strength and for injury risk screening. The aim of this study was to investigate the reliability of a field-based test to assess unilateral hamstring and quadriceps isometric muscle strength in a nearly extended position (30 knee flexion) in football players. Methods: Nineteen male football players completed the field-based test on two separate occasions, one week apart, to produce a test–retest design. To complete the test, participants performed maximal isometric efforts on a custom-built bench with 30 of knee flexion and 90 of hip flexion while the force applied was measured with a portable load cell at 80 Hz. On each occasion, participants performed two 2 s maximal isometric repetitions intending to flex and extend the knee to assess hamstring and quadriceps strength, respectively. In each repetition, the force developed during the maximum voluntary isometric contraction (MVIC) and rate of force development (RFD) metrics for hamstring (H) and quadriceps (Q) were collected, and the H:Q ratio was calculated afterwards. Results: MVIC showed the highest reliability for the measurement of both hamstring and quadriceps strength (ICC > 0.80, [95% CI: 0.55, 0.96]; CV 0.75, [95% CI: 0.48, 0.95]; CV < 15%, [95% CI: 8.9, 22.4]). RFD0–150 and RFD0–250 yielded moderate reliability values for hamstring strength (ICC = 0.78–0.86, [95% CI: 0.52, 0.94]; CV = 20–27%, [95% CI: 15, 39.7]). RFD0–50 presented the largest variability (ICC 25%, [95% CI: 19.2, 45.3]). Conclusions: The field-based test presented here provided reliable results for the measurement of maximal isometric hamstring and quadriceps strength and for the calculation of the H:Q ratio. However, the measurement of RFD with this test is less reliable. This test allows reliable field-based assessments of hamstring and quadriceps maximal isometric strength which can be helpful to identify muscle strength deficits and imbalances during injury prevention and management processes in football players.Ministry of Universities of Spain (grant number: FPU21/04536

New insights into bone morphogenetic protein signaling: focus on angiogenesis

The role of bone morphogenetic proteins (BMPs) in vasculogenesis is still not well understood, despite many recent developments in this area of research. In this review, we discuss the most recent studies that identify new critical mechanisms through which BMP signaling acts with a focus on angiogenesis

Bioaccessible peptides released by in vitro gastrointestinal digestion of fermented goat milks

In this study, ultrafiltered goat milks fermented with the classical starter bacteria Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus salivarus subsp. thermophilus or with the classical starter plus the Lactobacillus plantarum C4 probiotic strain were analyzed using ultra-high performance liquid chromatography-quadrupole-time-of-flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS) and/or liquid chromatography-ion trap (LC-IT-MS/MS). Partial overlapping of the identified sequences with regard to fermentation culture was observed. Evaluation of the cleavage specificity suggested a lower proteolytic activity of the probiotic strain. Some of the potentially identified peptides had been previously reported as angiotensin converting enzyme (ACE)-inhibitory, antioxidant and antibacterial and might account for the in vitro activity previously reported for these fermented milks. Simulated digestion of the products was conducted in presence of a dialysis membrane to retrieve the bioaccessible peptide fraction. Some sequences with reported physiological activity resisted digestion but were found in the non-dialyzable fraction. However, non-previously detected sequences such as the antioxidant αs1-casein 144YFYPQL149, the antihypertensive αs2-casein 90YQKFPQY96 and the antibacterial αs2-casein 165LKKISQ170 were found in the dialyzable fraction of both fermented milks. Moreover, in the fermented milk including the probiotic strain, the k-casein dipeptidyl peptidase IV inhibitor (DPP-IV) 51INNQFLPYPY60 as well as additional ACE-inhibitory or antioxidant sequences could be identified. With the aim to anticipate further biological outcomes, quantitative structure activity relationship (QSAR) analysis was applied to the bioaccessible fragments and led to propose potential ACE inhibitory sequences

Influence of a football match on landing biomechanics and jump performance in female football players

This study aimed to assess the acute effect of a competitive football match on jump performance and kinematic parameters during jump landing in semiprofessional female football players. Twenty-two semiprofessional players (20 ± 3 years) underwent a drop jump task for a posterior video analysis of the landing phase. These measurements were obtained at (1) baseline, (2) after, and (3) 48 h after a competitive football match. A one-way ANOVA with repeated measures was employed to detect differences over the time. There was a main effect of time for maximal knee flexion angle during drop landing (p = 0.001). In comparison with baseline, maximal knee flexion angle was reduced immediately post-match and was still reduced 48 h after the match (63.4 ± 8.6 vs 57.0 ± 11.7 vs 48.9 ± 19.1, p ≤ 0.038). There was also a main effect of time for drop jump height (p < 0.001). Drop jump height was reduced immediately post-match and remained low 48 h after the match in comparison with baseline (27.3 ± 3.6 vs 24.5 ± 2.8 ~ 25.5 ± 3.0 cm, p ≤ 0.002). There was a main effect of time on hip flexion angle during landing (p = 0.001), but the pairwise comparison revealed that this variable was not affected immediately post-match but was lower 48 h after the match than at baseline (50.1 ± 10.1 ~ 50.8 ± 13.2 vs 38.1 ± 17.8 °, p ≤ 0.005). A competitive football match worsened jump performance and several landing biomechanical parameters in female football players, which were still decreased in comparison with baseline even 48 h after the match