Correction:Carbonyl trapping and antiglycative activities of olive oil mill wastewater

Correction for ‘Carbonyl trapping and antiglycative activities of olive oil mill wastewater’ by Marta Navarro et al., Food Funct., 2015, 6, 574–583

Explorative investigation of the anti-glycative effect of a rapeseed by-product extract

Formation of Advanced Glycation End-products (AGEs) in biological systems are increased during hyperglycaemia due to higher levels of circulating glucose, as well as carbonyl reactive species. AGEs are causative factors of common chronic diseases. Since synthetic AGE-inhibitors exert unwanted side effects and polyphenols act as potent antiglycative agents, vegetables (fruits, seeds and related by-products) are good candidates for searching natural inhibitors. The aim of this research is to explore the suitability of a polyphenol-rich rapeseed cake extract (RCext) to decrease the formation of AGEs in an in vitro model. Total Phenolic Content, antioxidant, anti-glycative activity, specific inhibition of AGEs (pentosidine and argypyrimidine), and methylglyoxal trapping capacity of the RCext were evaluated. The metabolomic profile of the extract was also analysed through GC-MS. Different phenols, amino acids, carbohydrates, organic acids and fatty acids are identified in the RCE by GC-MS. Results confirm the high concentration of polyphenols correlated with the antioxidant capacity and anti-glycative activity in a dose dependent manner. Rapeseed cake extract (3.7 mg mL−1) significantly reduced the formation of free fluorescent AGEs and pentosidine up to 34.85%. The anti-glycative activity of the extract is likely to be due to the high concentration of sinapinic acid in its metabolic profile, and the mechanism of action is mediated by methylglyoxal trapping. Results show a promising potential for using rapeseed cake extract as a food supplement to ameliorate the formation of AGEs. Rapeseed cake extract should therefore be considered a potential candidate for the prevention of glycation-associated complications of age-related pathologie

Creencias estereotípicas sobre la mujer: reflexiones en torno a algunos datos de la situación en España

[Abstract] Gender...stereotyping of a representative sample (n=1254) of the Spanish popu... lation is analyzed. The existence of the traditional stereotype is confirtued, both in traits and roles. Women are perceived as more communal and expressive and are supposed to perform domestic activities and tasds. Men, on the other hand, are per... ceived as more agentic and instrumental, and it is believed that their main activity is outside...home employed work. At the sa111e ti111e, and with a different salnple of senior High School students (N=189), the existence of social discritnination toward W0111en who try to follow Technical Studies at college level is confinned. This fin... ding is interpreted as a proof of the itnpact and persiveness of gender stereotypes.[Resumen] Se estudia la estereotipia de género tuostrada por una muestra representativa de la población española (N=1254). Se encuentra que subsiste la estereotipia tradicio... nal tanto en rasgos como en roles. Las mujeres se perciben como más cOlllunales y expresivas y se considera que su actividad fundamental gira en torno al hogar, mien... tras que los hombres se perciben COtuO más agénticos e instrutuentales y se cree que su actividad fundatuental es el trabajo asalariado fuera del hogar. Se comprueba la existencia de discriminación social hacia tuujeres que estudian carreras técnicas en una llluestra de estudiantes de 3º de BUP (N=189), y se interpreta este hecho cotuo una delll0stración del impacto y penetración de los estereotipos de género

Effect of shear processing on the linear viscoelastic behaviour and microstructure of bitumen/montmorillonite/MDI ternary composites

Polymer modified bitumens (PMBs) have largely been utilized as a construction material. However, lack of affinity between bitumen and polymer leads to phase separation, and eventually, performance depletion. In this paper, alternative formulations of bitumen with an organically-modified montmorillonite (OMMT) Cloisite 20A® and polymeric methylene diphenyl diisocyanate (MDI) were prepared by melt blending. Their comprehensive rheological characterization evidenced improved linear viscoelastic properties when OMMT is added, revealing a noticeable structural reinforcement and thermal stability. Rheological data also showed that MDI-involved reactions control the composite end properties, being greatly influenced by the shear conditions applied

Design of a case management model for people with chronic disease (Heart Failure and COPD). Phase I: modeling and identification of the main components of the intervention through their actors: patients and professionals (DELTA-ICE-PRO Study

Background Chronic diseases account for nearly 60% of deaths around the world. The extent of this silent epidemic has not met determined responses in governments, policies or professionals in order to transform old Health Care Systems, configured for acute diseases. There is a large list of research about alternative models for people with chronic conditions, many of them with an advanced practice nurse as a key provider, as case management. But some methodological concerns raise, above all, the design of the intervention (intensity, frequency, components, etc). Methods/Design Objectives: General: To develop the first and second phases (theorization and modeling) for designing a multifaceted case-management intervention in people with chronic conditions (COPD and heart failure) and their caregivers. Specific aims: 1) To identify key events in people living with chronic disease and their relation with the Health Care System, from their point of view. 2) To know the coping mechanisms developed by patients and their caregivers along the story with the disease. 3) To know the information processing and its utilization in their interactions with health care providers. 4) To detect potential unmet needs and the ways deployed by patients and their caregivers to resolve them. 5) To obtain a description from patients and caregivers, about their itineraries along the Health Care System, in terms of continuity, accessibility and comprehensiveness of care. 6) To build up a list of promising case-management interventions in patients with Heart Failure and COPD with this information in order to frame it into theoretical models for its reproducibility and conceptualization. 7) To undergo this list to expert judgment to assess its feasibility and pertinence in the Andalusian Health Care. Design: Qualitative research with two phases: For the first five objectives, a qualitative technique with biographic stories will be developed and, for the remaining objectives, an expert consensus through Delphi technique, on the possible interventions yielded from the first phase. The study will be developed in the provinces of Almería, Málaga and Granada in the Southern Spain, from patients included in the Andalusian Health Care Service database with the diagnosis of COPD or Heart Failure, with the collaboration of case manager nurses and general practitioners for the assessment of their suitability to inclusion criteria. Patients and caregivers will be interviewed in their homes or their Health Centers, with their family or their case manager nurse as mediator. Discussion First of a series of studies intended to design a case-management service for people with heart failure and COPD, in the Andalusian Health Care System, where case management has been implemented since 2002. Accordingly with the steps of a theoretical model for complex interventions, in this study, theorization and intervention modeling phases will be developed.This research was carried out with the support of one research grant, awarded by the Regional Health Ministry of Andalusia (Exp. 0222/2008