Perfil dos escritórios contábeis do município de Tangará da Serra - MT

As in other areas, it is of paramount importance that accountants are able to perform their function, constantly training themselves in the face of a competitive market. This study aimed to identify the profile of accounting offices in the municipality of Tangará da Serra/MT and how those responsible have been prepared to follow the changes that occur in the technological scenario. This is a descriptive research with a quantitative nature. The results indicate that among the interviewees, the vast majority graduated in Accounting. The predominant gender among the interviewees was male (54.5%) and the age group 36 to 45 years (45.5%). Regarding the time of training, 81.8% of the professionals are over 10 years old. Most of the offices surveyed (68.2%) have over 11 years of existence, 64% have up to 05 employees and 40.9% have 21 to 44 active clients. It was concluded that those responsible for the accounting offices constantly update their staff, in order to monitor the changes that occurred in the accounting area.Como en otras áreas, es de suma importancia que los contadores puedan desempeñar su función, capacitándose constantemente en un mercado competitivo. Este estudio tiene como objetivo identificar el perfil de los talleres de contabilidad en el municipio de Tangará da Serra/MT y la forma en que los responsables se han estado preparando para acompañar los cambios que ocurren en el escenario tecnológico. Se trata de una investigación descriptiva de carácter cuantitativo. Los resultados indican que entre los entrevistados, la gran mayoría es licenciada en Ciencias Contables. El sexo predominante entre los encuestados fue el masculino (54,5%) y con edades entre 36 y 45 años (45,5%). En cuanto al tiempo de formación, el 81,8% de los profesionales tiene más de 10 años. La mayoría de los talleres encuestados (68,2%) tiene más de 11 años de existencia, el 64% tiene hasta 05 empleados y el 40,9% tiene de 21 a 44 clientes activos. Se concluyó que los responsables de los talleres de contabilidad están constantemente actualizando sus equipos, con el objetivo de estar todo el día con los cambios del área contable.Assim como em outras áreas, é de suma importância que os contabilistas estejam aptos para exercer sua função, se capacitando constantemente diante de um mercado competitivo. Este estudo teve como objetivo identificar o perfil dos escritórios contábeis do município de Tangará da Serra/MT e o modo como os responsáveis têm se preparado para acompanhar as mudanças que ocorrem no cenário tecnológico. Trata-se de uma pesquisa descritiva com natureza quantitativa. Os resultados apontam que dentre os entrevistados, a grande maioria é graduada em Ciências Contábeis. O gênero predominante entre os entrevistados foi o masculino (54,5%) e a faixa etária de 36 a 45 anos (45,5%). Quanto ao tempo de formação, 81,8% dos profissionais possuem acima de 10 anos. A maioria dos escritórios pesquisados (68,2%) possui acima de 11 anos de existência, 64% possuem até 05 colaboradores e 40,9% têm de 21 a 44 clientes ativos. Concluiu-se que os responsáveis pelos escritórios de contabilidade atualizam sua equipe constantemente, visando acompanhar as mudanças ocorridas na área contábil

Effect of collection methods of bovine ruminal fluid on ruminal and microbiological paramethers

Estudou-se o efeito de três métodos de coleta (manual, bomba a vácuo e sonda nasoesofageana) sobre os teores de ácidos graxos voláteis totais (AGVt), nitrogênio amoniacal e número de protozoários no fluido ruminal de bovino. Utilizou-se o delineamento inteiramente casualizado, com três tratamentos e cinco repetições. Os resultados revelaram que o método da sonda nasoesofageana proporcionou valores menores dos ácidos propiônico, butírico, AGVt e de nitrogênio amoniacal no fluido ruminal. O número total de protozoários não foi afetado pelos métodos de coleta de conteúdo ruminal. O método de coleta manual e por meio de bomba a vácuo mostraram-se eficientes para os parâmetros estudados.An experiment was conducted to determine the effects of three methods of collection on volatile fatty acids concentrations, amoniacal nitrogen levels and protozoa number in ruminal fluid of bovine. Three methods of collection were used: manual, vacuum-pump and with a nasal-esophagic tube. It was used a completely randomized design with three treatments and five replications. The data showed that the nasal-esophagic tube method resulted in lower values of propionic acid, butiric acid, volatile fatty acids and amoniacal nitrogen in ruminal fluid. The total number of protozoa do not affected by the methods of fluid collection. The manual and the vacuum-pump method showed an indicated methods for the determinations of the studied parameters

Relationships between follicle and corpus luteum size and vascularization with ovulation, progesterone production, and pregnancy in Nellore beef cattle

ABSTRACT The objective of this study was to evaluate the relationships between preovulatory follicle (POF) and corpus luteum (CL) diameters, and POF and CL vascular perfusion with progesterone production, ovulation, and pregnancy in Nellore cows subjected to timed artificial insemination (TAI). Nellore cows (n = 201) were subjected to ovulation synchronization and later to ultrasound evaluation of POF and CL at the time of insemination (D0) and seven days later (D7), respectively. Females were divided into three categories according to the POF diameter assessed at the time of insemination: small (SF), medium (MF), and large (LF) follicles. The LF group had a greater number and intensity of pixels in the POF ultrasound exam compared with the SF group. The CL flow intensity and progesterone concentration were also higher in the LF group. The SF group showed lower flow intensity and lower ovulation rate compared with the others. When non-pregnant females were compared to pregnant ones, no difference was observed in any of the analyzed variables. The results show for the first time in Nellore cattle the relationship between the size of ovarian structures and blood flow (quantity and intensity) as well as the ability of the CL to produce progesterone. The intensity of the POF pixels proved to be relevant, demonstrating correlations with the size and flow of the CL, which were not found when evaluating only the number of pixels, thus revealing the importance of evaluating complementary characteristics of the flow

Occurrence of eggs and oocysts of gastrointestinal parasites in passerine birds kept in captivity in Para State, Brazil Ocorrência de ovos e oocistos de parasitos gastrointestinais em aves Passeriformes mantidas em cativeiro no estado do Pará, Brasil

ABSTRACT The objective of this study was to detect helminth eggs and protozoan oocysts in samples of feces from birds of the orde

Antifungal activity of amphotericin B conjugated to nanosized magnetite in the treatment of paracoccidioidomycosis

This study reports on in vitro and in vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising amphotericin B loaded onto the surface of pre-coated (with a double-layer of lauric acid) magnetite nanoparticles. The in vitro tests compared two drugs; i.e., this newly developed form and free amphotericin B. We found that this nanocomplex exhibited antifungal activity without cytotoxicity to human urinary cells and with low cytotoxicity to peritoneal macrophages. We also evaluated the efficacy of the nanocomplex in experimental paracoccidioidomycosis. BALB/c mice were intratracheally infected with Paracoccidioides brasiliensis and treated with the compound for 30 or 60 days beginning the day after infection. The newly developed amphotericin B coupled with magnetic nanoparticles was effective against experimental paracoccidioidomycosis, and it did not induce clinical, biochemical or histopathological alterations. The nanocomplex also did not induce genotoxic effects in bone marrow cells. Therefore, it is reasonable to believe that amphotericin B coupled to magnetic nanoparticles and stabilized with bilayer lauric acid is a promising nanotool for the treatment of the experimental paracoccidioidomycosis because it exhibited antifungal activity that was similar to that of free amphotericin B, did not induce adverse effects in therapeutic doses and allowed for a reduction in the number of applications

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies

There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity