195 research outputs found
Enhanced Electrokinetic Transport of Sulfate in Saline Soil
The electrokinetic transport of sulfate was investigated as a means of treating and restoring a sulfate-accumulating saline soil. The electrokinetic treatment decreased the electrical conductivity of the soil, an indicator of soil salinity, to 58.6%, 73.1%, and 83.5% for 7, 14 and 21 days, respectively. More than 96% of the chloride and nitrate were removed within 7 days. However, the removal of sulfate was highly influenced by the anode material. An iron anode removed sulfate effectively, whereas, sulfate was hyper-accumulated in the anodic region when an inert anode was used. The iron anode was oxidized in a sacrificial anodic reaction, which competed with the electrolysis reaction of water at the anode, and finally the reaction prevented the severe acidification of the soil in the anodic region. However, the competing reactions produced hydrogen ions at the anode, and the ions were transported toward the cathode, which, in turn, acidified the soil, especially, in the anodic region. The acidification switched the surface charge of the soil from negative to positive, increasing the interaction between the soil surface and sulfate, and thus inhibiting the transport of sulfate under the electric field. The zeta potential analysis of the soil provided an explanation. The results indicate that preventing severe acidification is an important factor which influences the transport of anions and iron anode for the enhanced removal of anionic pollutants by electrokinetic remediation
Immunization Dynamics on a 2-layer Network Model
We introduce a 2-layer network model for the study of the immunization
dynamics in epidemics. Spreading of an epidemic is modeled as an excitatory
process in a small-world network (body layer) while immunization by prevention
for the disease as a dynamic process in a scale-free network (head layer). It
is shown that prevention indeed turns periodic rages of an epidemic into small
fluctuation. The study also reveals that, in a certain situation, prevention
actually plays an adverse role and helps the disease survive. We argue that the
presence of two different characteristic time scales contributes to the
immunization dynamics observed.Comment: 5 pages, 7 figure
Assessment of Soil Washing for Simultaneous Removal of Heavy Metals and Low-Level Petroleum Hydrocarbons Using Various Washing Solutions
Bench-scale soil washing experiments were conducted for simultaneous removal of heavy metals (Pb, Cu, Zn) and low-level petroleum hydrocarbon contaminants from soils. Various washing solutions including hydrochloric acid (HCl), nitric acid (HNO3), sulfuric acid (H2SO4), tartaric acid (C4H6O6) and ethylenediaminetetraacetic acid (C10H16N2O8, EDTA) were used. The concentration of the washing solutions ranged from 0.1 to 3M with a liquid-to-solid ratio of 10. The soil washing results showed that hydrochloric acid (HCl) was the best washing solution at 3M for heavy metal removal. Other washing solutions also showed a significant removal of heavy metals, except for sulfuric acid (H2SO4). Sulfuric acid (H2SO4) exhibited the worst performance among all washing solutions used with respect to Pb removal. 1M HCl and HNO3were sufficient for effective Pb and Cu removal, and all of the tested washing solutions at a concentration of 0.1M produced results compliant with the Korean warning standard for Zn removal. In the case of total petroleum hydrocarbons (TPH), tartaric acid (C4H6O6) produced the highest removals at all concentration levels compared with other washing solutions. More specifically, TPH removal efficiencies exceeded 33 and 82 % at the lowest (0.1M) and highest (3M) tartaric acid (TA) concentrations, respectively. Overall, TA could be a viable washing solution for the removal of both heavy metals (Pb, Cu, Zn) and TPH from contaminated soils
Aortic Dissection and Rupture in a Child
After developing sudden severe chest pain, an 11-year-old boy presented to the emergency room with chest pain and palpitations and was unable to stand up. The sudden onset of chest pain was first reported while swimming at school about 30 minutes prior to presentation. Arterial blood pressure (BP) was 150/90 mmHg, heart rate was 120/minute, and the chest pain was combined with shortness of breath and diaphoresis. During the evaluation in the emergency room, the chest pain worsened and abdominal pain developed. An aortic dissection was suspected and a chest and abdomen CT was obtained. The diagnosis of aortic dissection type B was established by CT imaging. The patient went to surgery immediately with BP control. He died prior to surgery due to aortic rupture. Here we present this rare case of aortic dissection type B with rupture, reported in an 11-year-old Korean child
Congenital Syphilis Presenting with a Generalized Bullous and Pustular Eruption in a Premature Newborn
Congenital syphilis occurs when Treponema pallidum crosses the placenta during pregnancy or from contact with an infectious genital lesion during delivery. Cutaneous manifestations of congenital syphilis are relatively common, occurring in approximately 30% to 70% of patients. Maculopapular lesions, vesiculobullous lesions, condylomata lata lesions, annular lesions, and erythema multiforme-like targetoid lesions have been reported. We report on a premature newborn with congenital syphilis who presented with generalized bullous and pustular eruption and desquamation at birth
Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) Reduce the Expression of Toll-Like Receptor 4 in Mice with Alcoholic Liver Disease
Objective
The role of lipopolysaccharide (LPS) and toll-like receptor 4 (TLR 4) in the pathogenesis of alcoholic liver disease (ALD) has been widely established. We evaluated the biological effects of probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052), KRG (Korea red ginseng), and urushiol (Rhus verniciflua Stokes) on ALD, including their effects on normal and high-fat diet in mice.
Methods
One hundred C57BL/6 mice were classified into normal (N) and high-fat diet (H) groups. Each group was divided into 5 sub-groups: control, alcohol, alcohol+probiotics, alcohol+KRG, and alcohol+urushiol. A liver function test, histology, electron-microscopy, interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-6, and IL-10, and TLR 4 were evaluated and compared.
Results
In the N group, probiotics, KRG, and urushiol significantly reduced levels of TNF-α (12.3±5.1, 13.4±3.9, and 12.1±4.3 vs. 27.9±15.2 pg/mL) and IL-1β (108.4±39.4, 75.0±51.0, and 101.1±26.8 vs. 162.4±37.5 pg/mL), which were increased by alcohol. Alcohol-induced TLR 4 expression was reduced by probiotics and urushiol (0.7±0.2, and 0.8±0.1 vs. 1.0±0.3, p<0.001). In the H group, IL-10 was significantly increased by probiotics and KRG, compared with alcohol (25.3±15.6 and 20.4±6.2 vs. 7.6±5.6 pg/mL) and TLR 4 expression was reduced by probiotics (0.8±0.2 vs. 1.0±0.3, p = 0.007).
Conclusions
Alcohol-induced TLR 4 expression was down-regulated by probiotics in the normal and high-fat diet groups. Probiotics, KRG, and urushiol might be effective in the treatment of ALD by regulating the gut-liver axis
Bladder Reconstruction Using Bovine Pericardium in a Case of Enterovesical Fistula
The use of graft materials in bladder mucosa has been examined in animal models, but debate exists over which materials are effective. Intestine has been used as a substitute in augmentation cystoplasty for patients with neuropathic bladder, but serious adverse effects of the operation have occurred in some instances. We report a case of a successful repair of an enterovesical fistula by use of bovine pericardium. The patient has remained well for 2.5 years. We suggest that bovine pericardium may be a suitable option as a bladder substitute
Progression of Prostate Cancer Despite an Extremely Low Serum Level of Prostate-Specific Antigen
A 61-year-old man who had been diagnosed with prostate cancer 9 years ago and had been treated with pelvic irradiation and intermittent androgen deprivation therapy visited the emergency room because of back pain and weakness in both legs. Spine magnetic resonance imaging showed a lumbar epidural mass and spine metastasis. The whole-body workup revealed multiple metastases to the lymph nodes, bone, liver, and lung. The serum prostate-specific antigen was 0.02 ng/ml. He underwent laminectomy, posterior fixation, and epidural mass excision, and metastatic adenocarcinoma from the prostate was diagnosed. The patient underwent 1 cycle of docetaxel-based chemotherapy. More chemotherapy could not be done because of his general weakness. The patient died one month later of multiple organ failure
Effects of Korean Red Ginseng (Panax ginseng), urushiol (Rhus vernicifera Stokes), and probiotics (Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) on the gut–liver axis of alcoholic liver disease
AbstractBackgroundRoles of immune reaction and toll-like receptor-4 (TLR-4) have widely been established in the pathogenesis of alcoholic liver disease (ALD).MethodsWe evaluated the biologic efficacy of Korean Red Ginseng (KRG), urushiol, and probiotics (Lactobacillus rhamnosus R0011 and Lactobacillus acidophilus R0052) in mouse models of ALD. Sixty C57BL/6 mice were equally divided into six feeding groups for 10 weeks: normal diet, alcohol, control, alcohol + KRG, alcohol + urushiol, and alcohol + probiotics. Alcohol was administered via a Lieber–DeCarli liquid diet containing 10% alcohol. TLR-4 expression, proinflammatory cytokines, and histology, as well as the results of liver function tests were evaluated and compared.ResultsNo between-group differences were observed with regard to liver function. TLR-4 levels were significantly lower in the KRG, urushiol, and probiotics groups than in the alcohol group (0.37 ± 0.06 ng/mL, 0.39 ± 0.12 ng/mL, and 0.33 ± 0.07 ng/mL, respectively, vs. 0.88 ± 0.31 ng/mL; p < 0.05). Interleukin-1β levels in liver tissues were decreased among the probiotics and KRG groups. The tumor necrosis factor-α level of liver tissue was decreased in the KRG group.ConclusionThe pathological findings showed that alcohol-induced steatosis was significantly reduced by KRG and urushiol. As these agents improve immunologic capacity, they may be considered in potential anti-ALD treatments
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