Heavy ion beam probe measurements of radial potential profiles in the modified Penning discharge

A heavy ion beam probe was used to examine the radial potential profile of a plasma in the modified Penning discharge. The plasma has strong (approximately kV) electrostatic potentials near the anode ring which can be a large fraction of the injected ion beam energy. A primary (singly ionized) thallium ion beam is injected through the plasma in the midplane of a double Penning anode ring. After passage through the plasma, primary and secondary (doubly ionized) ions are detected with either a set of flat probes or an electrostatic energy analyzer. A calculation of the primary orbit through the plasma is performed to obtain an approximation to the measured primary beam trajectory. As the real radial potential profile is unknown, an adjustable model is used in the computer program. The adjustable potential profile is varied until the best agreement between measured and calculated trajectories is obtained. Secondary orbits are also predicted using the best fitting adjustable profile. The calculations indicate that secondary beams originating at more than one point in the plasma can be simultaneously observed at the electrostatic analyzer with certain primary beam initial conditions

A heavy ion beam probe system for investigation of a modified Penning discharge

An ion beam probe diagnostic system can measure time- and space-resolved profiles of plasma space potential and electron density. In combination with a computer iterative technique, the ion beam probe can determine both the space potential profile in plasmas containing strong electric fields and potentials comparable in magnitude to the energy of the probing ion beam. During ion beam probing of a modified Penning discharge, several groups of secondary ions were observed coming from the plasma with a fixed primary beam energy and momentum. The energies of these ions were within 10 percent of the values predicted by a computer-generated model of the potential profile in the plasma. The mechanical and electronic components of the system are described, with particular emphasis on those features required to probe plasma potentials comparable in magnitude to the ion beam energy

Características morfohistológicas y cuantitativas del tegumento de Odontophrynus americanus (Amphibia, Odontophrynidae). Análisis comparado en dos ambientes con diferentes niveles de perturbación.

Tesina (Grado en Ciencias Biológicas)--Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Lugar de Trabajo: Cátedra de Anatomía Comparada y Morfología Animal. Departamento de Diversidad Biológica y Ecología. 2016. 38 h.; tabls.; figras; ils. Contiene Referencias Bibliográficas.Se analizó el tegumento de individuos adultos de Odontophrynus americanus, provenientes de dos ambientes con diferentes niveles de perturbación antrópica con el fin de evaluar la presencia de variaciones morfohistológicas. Se utilizaron diez individuos adultos agrupados en dos lotes, uno proveniente de un agroecosistema del sur de la Provincia de Córdoba, caracterizado por presentar alta perturbación antrópica y el otro de un bosque fluvial de la Provincia de Santa Fe en donde no existen fuentes notables de contaminación. De cada ejemplar se tomaron muestras del tegumento de las regiones medio dorsal, medio ventral e inguinal. Las mismas se procesaron según técnicas histológicas de rutina para luego realizar cortes seriados de 5 μm de espesor los que se colorearon, a los fines de determinar la morfohistología, con hematoxilina-eosina, Tricrómico de Casson y técnica de Von Kossa. Para conocer la naturaleza de las secreciones glandulares se utilizaron las siguientes técnicas histoquímicas: Periodic Acid Schiff, Alcian Blue pH 2,5 y azul de toluidina. En base a los resultados se concluye que el sistema tegumentario de Odontophrynus americanus sigue el diseño básico descripto para anuros. En ningún ejemplar se observó la capa Eberth-Katschenko. Los individuos procedentes del agroecosistema presentan un mayor espesor tegumentario en la región inguinal, seguido por la región medio ventral y finalmente la medio dorsal. En los ejemplares del bosque fluvial se observó la situación inversa. Los tipos glandulares que se identifican en todos los ejemplares analizados son las glándulas mucosas y serosas, siendo las primeras más numerosas en todas las regiones corporales analizadas. Solo se observaron diferencias significativas en relación a la histomorfometría entre los ejemplares procedentes del agroecosistema y del bosque fluvial en la mayoría de las regiones corporales y entre los estratos de las mismas. Los resultados indican que, posiblemente, la utilización de agroquímicos entre los meses de mayor actividad de estos anfibios, serían los responsables de las alteraciones detectadas

Extracting CNG TLS/SSL artifacts from LSASS memory

Currently, there is no publicly accessible, reliable, automated way to forensically decrypt Secure Socket Layer (SSL)/Transport Layer Security (TLS) connections that leverage ephemeral key negotiations as implemented by the modern Windows operating system. This thesis explores the Local Security Authority Sub-System (LSASS) process used for Key Isolation within the Windows 10 operating system in pursuit of identifying artifacts that would allow a solution to that problem, along with any other connection artifacts that could provide forensic value. The end result was the identication of TLS/SSL secrets from the key exchange and contextual artifacts that provide identication of the other party to a connection and negotiated parameters. This led to an automated method for extraction through implementation of a plugin for the Volatility framework, a widely used and accepted memory forensics framework

Gearing effects of the patella (knee extensor muscle sesamoid) of the helmeted guineafowl during terrestrial locomotion

Human patellae (kneecaps) are thought to act as gears, altering the mechanical advantage of knee extensor muscles during running. Similar sesamoids have evolved in the knee extensor tendon independently in birds, but it is unknown if these also affect the mechanical advantage of knee extensors. Here, we examine the mechanics of the patellofemoral joint in the helmeted guineafowl Numida meleagris using a method based on muscle and tendon moment arms taken about the patella's rotation centre around the distal femur. Moment arms were estimated from a computer model representing hindlimb anatomy, using hip, knee and patellar kinematics acquired via marker‐based biplanar fluoroscopy from a subject running at 1.6 ms−1 on a treadmill. Our results support the inference that the patella of Numida does alter knee extensor leverage during running, but with a mechanical advantage generally greater than that seen in humans, implying relatively greater extension force but relatively lesser extension velocity

High Bulk Modulus of Ionic Liquid and Effects on Performance of Hydraulic System

Over recent years ionic liquids have gained in importance, causing a growing number of scientists and engineers to investigate possible applications for these liquids because of their unique physical and chemical properties. Their outstanding advantages such as nonflammable liquid within a broad liquid range, high thermal, mechanical, and chemical stabilities, low solubility for gases, attractive tribological properties (lubrication), and very low compressibility, and so forth, make them more interesting for applications in mechanical engineering, offering great potential for new innovative processes, and also as a novel hydraulic fluid. This paper focuses on the outstanding compressibility properties of ionic liquid EMIM-EtSO4, a very important physical chemically property when IL is used as a hydraulic fluid. This very low compressibility (respectively, very high Bulk modulus), compared to the classical hydraulic mineral oils or the non-flammable HFDU type of hydraulic fluids, opens up new possibilities regarding its usage within hydraulic systems with increased dynamics, respectively, systems’ dynamic responses

Cancellous bone and theropod dinosaur locomotion. Part III—Inferring posture and locomotor biomechanics in extinct theropods, and its evolution on the line to birds

This paper is the last of a three-part series that investigates the architecture of cancellous bone in the main hindlimb bones of theropod dinosaurs, and uses cancellous bone architectural patterns to infer locomotor biomechanics in extinct non-avian species. Cancellous bone is highly sensitive to its prevailing mechanical environment, and may therefore help further understanding of locomotor biomechanics in extinct tetrapod vertebrates such as dinosaurs. Here in Part III, the biomechanical modelling approach derived previously was applied to two species of extinct, non-avian theropods, Daspletosaurus torosus and Troodon formosus. Observed cancellous bone architectural patterns were linked with quasi-static, three-dimensional musculoskeletal and finite element models of the hindlimb of both species, and used to derive characteristic postures that best aligned continuum-level principal stresses with cancellous bone fabric. The posture identified for Daspletosaurus was largely upright, with a subvertical femoral orientation, whilst that identified for Troodon was more crouched, but not to the degree observed in extant birds. In addition to providing new insight on posture and limb articulation, this study also tested previous hypotheses of limb bone loading mechanics and muscular control strategies in non-avian theropods, and how these aspects evolved on the line to birds. The results support the hypothesis that an upright femoral posture is correlated with bending-dominant bone loading and abduction-based muscular support of the hip, whereas a crouched femoral posture is correlated with torsion-dominant bone loading and long-axis rotation-based muscular support. Moreover, the results of this study also support the inference that hindlimb posture, bone loading mechanics and muscular support strategies evolved in a gradual fashion along the line to extant birds

Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes

Objective: To identify an appropriate cell source for the generation of meniscus substitutes, among those which would be available by arthroscopy of injured knee joints. Methods: Human inner meniscus cells, fat pad cells (FPC), synovial membrane cells (SMC) and articular chondrocytes (AC) were expanded with or without specific growth factors (Transforming growth factor-betal, Fibroblast growth factor-2 and Plate let-derived growth factor bb, TFP) and then induced to form three-dimensional cartilaginous tissues in pellet cultures, or using a hyaluronan-based scaffold (Hyaff(R)-11), in culture or in nude mice. Human native menisci were assessed as reference. Results: Cell expansion with TFP enhanced glycosaminoglycan (GAG) deposition by all cell types (up to 4.1-fold) and messenger RNA expression of collagen type II by FPC and SMC (up to 472-fold) following pellet culture. In all models, tissues generated by AC contained the highest fractions of GAG (up to 1.9 were positively stained for collagen type II (specific of the inner avascular region of meniscus), type IV (mainly present in the outer vascularized region of meniscus) and types I, III and VI (common to both meniscus regions). Instead, inner meniscus, FPC and SMC developed tissues containing negligible GAG and no detectable collagen type II protein. Tissues generated by AC remained biochemically and phenotypically stable upon ectopic implantation. Conclusions: Under our experimental conditions, only AC generated tissues containing relevant amounts of GAG and with cell phenotypes compatible with those of the inner and outer meniscus regions. Instead, the other investigated cell sources formed tissues resembling only the outer region of meniscus. It remains to be determined whether grafts based on AC will have the ability to reach the complex structural and functional organization typical of meniscus tissue. (C) 2006 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights rese

Grading systems in head and neck dysplasia: their prognostic value, weaknesses and utility

Contains fulltext : 80594.pdf (publisher's version ) (Open Access)ABSTRACT: BACKGROUND: Grading of dysplasia, including head and neck lesions, continues to be a hotly debated subject. It is subjective and lacks intra- and inter-observer reproducibility due to the insufficiency of validated morphological criteria and the biological nature of dysplasia. Moreover, due to the absence of a consensus, several systems are currently employed. OBJECTIVES: The aims of this review are to:1) Highlight the significance of dysplasia and the importance of a valid method for assessing precursor lesions of the head and neck.2) Review the different histopathological classification systems for grading intraepithelial lesions of the head and neck.3) Discuss and review quality requirements for these grading systems. CONCLUSION: Regarding the different classification systems, data concerning the WHO classification system are the most available in current literature. There is no simple relationship or overlapping between the classification systems. Further studies should be done to see whether other systems have advantages above the current WHO system and to discover indications that could lead to an universal classification system for intraepithelial lesions of the head and neck