94 research outputs found
A prospective cross-over study to evaluate the effect of two different occlusal concepts on the masseter muscle activity in implant-retained mandibular overdentures
- Publication venue
- Springer Nature
- Publication date
- 01/01/2015
- Field of study
A prospective multicentre study evaluating the outcomes of the abdominal wall dehiscence repair using posterior component separation with transversus abdominis muscle release reinforced by a retro-muscular mesh: filling a step
- Author
- Abdelaziz I. A. Ibrahim
- Abdulzahra Hussain
- Abd‑Elfattah Kalmoush
- Ahmed Mahmoud Abdou
- Ahmed Raafat
- Alaa A. Fiad
- Alfonso García Fadrique
- Gamal Osman
- Ibrahim A. Heggy
- Jose Bueno‑Lledó
- Khaled Safwat
- Massimo Chiaretti
- Mohamed Elnemr
- Mohamed I. Abdelhamid
- Mostafa M. Elaidy
- Muhammad Ali Baghdadi
- Tamer A. A. M. Habeeb
- Tamer Wasefy
- Vishal Shelat
- Waleed A. Abdelhady
- Walid A. Mawla
- Wessam Amr
- Publication venue
- Springer Nature
- Publication date
- 01/01/2023
- Field of study
Background This study aimed to evaluate the results of posterior component separation (CS) and transversus abdominis muscle release (TAR) with retro-muscular mesh reinforcement in patients with primary abdominal wall dehiscence (AWD). The secondary aims were to detect the incidence of postoperative surgical site occurrence and risk factors of incisional hernia (IH) development following AWD repair with posterior CS with TAR reinforced by retromuscular
mesh. Methods Between June 2014 and April 2018, 202 patients with grade IA primary AWD (Björck’s first classification) following midline laparotomies were treated using posterior CS with TAR release reinforced by a retro-muscular mesh in a prospective multicenter cohort study. Results The mean age was 42 ± 10 years, with female predominance (59.9%). The mean time from index surgery (midline laparotomy) to primary AWD was 7 ± 3 days. The mean vertical length of primary AWD was 16 ± 2 cm. The median time from primary AWD occurrence to posterior CS + TAR surgery was 3 ± 1 days. The mean operative time of posterior CS + TAR was 95 ± 12 min. No recurrent AWD occurred. Surgical site infections (SSI), seroma, hematoma, IH, and infected mesh occurred in 7.9%, 12.4%, 2%, 8.9%, and 3%, respectively. Mortality was reported in 2.5%. Old age, male gender, smoking, albumin level < 3.5 gm%, time from AWD to posterior CS + TAR surgery, SSI, ileus, and infected
mesh were significantly higher in IH. IH rate was 0.5% and 8.9% at two and three years, respectively. In multivariate logistic regression analyses, the predictors of IH were time from AWD till posterior CS + TAR surgical intervention, ileus, SSI, and infected mesh.
Conclusion Posterior CS with TAR reinforced by retro-muscular mesh insertion resulted in no AWD recurrence, low IH rates, and low mortality of 2.5%.
Trial registration Clinical trial: NCT05278117
In vitro cytotoxicity of Withania somnifera (L.) roots and fruits on oral squamous cell carcinoma cell lines: a study supported by flow cytometry, spectral, and computational investigations
- Author
- Publication venue
- Frontiers Media S.A.
- Publication date
- 01/01/2024
- Field of study
Oral cancer is a severe health problem that accounts for an alarmingly high number of fatalities worldwide. Withania somnifera (L.) Dunal has been extensively studied against various tumor cell lines from different body organs, rarely from the oral cavity. We thus investigated the cytotoxicity of W. somnifera fruits (W-F) and roots (W-R) hydromethanolic extracts and their chromatographic fractions against oral squamous cell carcinoma (OSCC) cell lines [Ca9-22 (derived from gingiva), HSC-2, HSC-3, and HSC-4 (derived from tongue)] and three normal oral mesenchymal cells [human gingival fibroblast (HGF), human periodontal ligament fibroblast (HPLF), and human pulp cells (HPC)] in comparison to standard drugs. The root polar ethyl acetate (W-R EtOAc) and butanol (W-R BuOH) fractions exhibited the strongest cytotoxicity against the Ca9-22 cell line (CC50 = 51.8 and 40.1 μg/mL, respectively), which is relatively the same effect as 5-FU at CC50 = 69.4 μM and melphalan at CC50 = 36.3 μM on the same cancer cell line. Flow cytometric analysis revealed changes in morphology as well as in the cell cycle profile of the W-R EtOAc and W-R BuOH-treated oral cancer Ca9-22 cells compared to the untreated control. The W-R EtOAc (125 μg/mL) exerted morphological changes and induced subG1 accumulation, suggesting apoptotic cell death. A UHPLC MS/MS analysis of the extract enabled the identification of 26 compounds, mainly alkaloids, withanolides, withanosides, and flavonoids. Pharmacophore-based inverse virtual screening proposed that BRD3 and CDK2 are the cancer-relevant targets for the annotated withanolides D (18) and O (12), and the flavonoid kaempferol (11). Molecular modeling studies highlighted the BRD3 and CDK2 as the most probable oncogenic targets of anticancer activity of these molecules. These findings highlight W. somnifera’s potential as an affordable source of therapeutic agents for a range of oral malignancies
Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey
- Author
- Abbas Ahmed Hosam Eldin Hasan
- Abbas Ghanem
- Abbas Hazem
- Abbatini Francesca
- Abdalbakheet Duaa
- Abdallah Emad
- Abdelazim Tarek
- Abdelaziz Nabil Yassin Tammam
- Abdelglil Momen
- Abdelhalim Ahmed
- Abdelhalim Mostafa Mohammed
- Abdelhamid Ahmed
- Abdelhamid Mohamed Sayed
- Abdelkhalik Morsi Mohamed Morsi
- Abdellatif Ahmed
- Abdelmageed Mohammed Elkassaby
- Abdelmaksoud Mohamed
- Abdelmohsen Ahmed
- Abdelmomen Ahmed Ezzat Elghrieb
- Abdelmoneim Ibrahim Tharwat Mohamed
- Abdelmonem Mohamed Ahmed
- Abdelmotaleb Hussien Ali
- Abdelrafee Ahmed
- Abdelrasheed Sayed
- Abdelsayed Emad Fahim
- Abdo Nael
- Abdulatef Shehab Ahmed Ali
- Abdullah Alqahtani Ali
- Abdulrahman Chadi
- Abdur-Rahman Lukman
- Abduraboh Abdullah Fayez
- Abed Ali Ibrahim Eldawy
- Abiodun Azeez Lateef
- Abiyere Henry
- Aboelmagid Hamdy Haggag Ebrahim
- Abolnasr Khaled Samir
- Abosi-Appeadu Kessewa
- Abouelnagah Galal
- Abozeid Ahmad Mahmoud
- Abozeid Mahmoud
- Abualkhair Wael
- Abualnaja Yousra
- Abualsel Abdulmenem
- Abuosba Abdelrahman
- Abusalem Osama
- Abusiam Wael
- Abutalib Raid Abdullah
- Abuzeid Mohamed Mostafa
- Addari Giulio
- Adebowale Yusuf
- Adejumo Adeyinka
- Adel Mohammed
- Adeoluwa Ojajuni
- Adeyeye Ademola
- Adly Ramy Magdy
- Adorisio Ottavio
- Agbonrofo Peter
- Agrawal Abhishek
- Ahmad Farooq
- Ahmad Misbahu Haruna
- Ahmad Mustafa
- Ahmad Sufian
- Ahmad Suhaib
- Ahmed Abeer Abdul Hameed
- Ahmed Arooj
- Ahmed Emad Ali
- Ahmed Hassan
- Ahmed Mohamed
- Ahmed Mostafa Mahmoud
- Aitali Abdelmounaim
- Akeel Nouf
- Akhtar Khalid
- Akin Furkan Atakan
- Akinmade Akinola
- Al Eisa Abdulmohsen
- Al Hassn Ibrahim
- Al Naeb Mohamed
- Al Turki Neamat Ahmed Ali
- Al-Bahrani Ahmed
- Al-Kubati Waheeb
- Al-Masari Hayder Makki
- Al-Sadery Humood
- Alaa Mohammed
- Alabbas Haytham
- Alafghani Haitham
- Alarabi Rayan
- Alawadhi Abdulbari Mohammed
- Alawady Mohammed
- Alawfi Homoud
- Alazzam Saleh
- Albadry Ali Almahdy Ali
- Albahooth Khalid
- Albalawi Ibrahim Altedlawi
- Albeshri Khalid A.
- Aleksandr Ogoreltsev
- Alfalah Haitham
- Algatanesh Nassib
- Alghamdi Faisal Saleh
- Alghamdi Saleh
- Alghuliga Abdullah
- Alhamdany Arkan Shubber
- Alharbi Abdulhamid
- Alhazmi Barrag
- Alhazmi Waleed
- Alhedaithy Alhanouf
- Alhendawey Moaaz
- Alhussaini Mohammed Khalid
- Alhussien Fade Ahmed
- Ali Ali Sayed
- Ali Bandar Idrees A.
- Ali Doaa
- Ali Mahmoud
- Ali Mohamed Anwar Abdel Razik
- Ali Muhammad Zulfiqar
- Ali Shabeer
- Ali Syed Muhammad
- Aliyu Yakubu
- Aljathlany Yousef
- Aljawhari Adel Ali
- Alkhalegy Ayman
- Alkhayat Ali
- Alkhayat Mohammed Amer
- Allaeys Mathias
- Almaghrabi Alhassan Hesham
- Almasri Mahmoud
- Almulhim Abdulrhman
- Alnabarawi Mahmoud
- Alnahas Yousef
- Alnashar Ahmed
- Alnoqaidan Emad
- Alomieri Adil
- Alotaibi Abdullah
- Alotaibi Abdulrahman
- Alotaibi Abdulrahman
- Alowairdhi Tumadher
- Alqarni Ahmed
- Alqasaby Abdallah
- Alqudaihi Heba
- Alrashidi Yousef
- Alsallum Ofays
- Alsawat Salem
- Alshabi Yaser Ahmad
- Alshehari Mohammed Mohammed Hasan
- Alshukr Sarah
- Alsuwaimel Munir A.
- Althobaiti Majid
- Althumali Abdullah
- Altomare Donato F.
- Alvarez Gallesio José Maria
- Alwan Ahmed
- Alwusaibie Ahmed
- Alyami Mohammad
- Alzahrani Khalid H.
- Alzahrani Saud
- Alzamanan Mahdi
- Alzamel Heythem
- Amal Benzakour
- Amary Mohamed Mokhtar
- Amen Mohamed Mohsen
- Amer Nasser Mohammed
- Amir Mohammed
- Amr Wesam
- Andrea Chierici
- Andrea Police
- Andriola Valeria
- Angrisani Marco
- Angulo Victor Manuel Pinto
- Antonio D’Alessandro
- Anwer Mariyah
- Aoun Rany
- Arbutina Dragana
- Archid Rami
- Aremu Isiaka
- Argenio Giulio
- Arnold Marion
- Arnouse Mohamed Mohamed Hamdy
- Asar Khalid Mohammad Ibrahim
- Ashimov Erkin
- Ashraf Tamer
- Asif Muhammad
- Aslam Mohammad
- Ateeb Mujammad
- Atef Gehad
- Atici Semra Demirli
- Attia Ahmed Mohamed
- Ayoub Larissa
- Azer Mina
- Aziz Mina
- Aziz Muhammad Akram Abdul
- Ba Mamadou
- Bacher Annica
- Bafaraj Ahmed
- Bagaglini Giulia
- Balla Andrea
- Barbary Hesham
- Barberis Andrea
- Barbon Carlotta
- Basendowah Mohammed
- Bashah Moataz M.
- Bashir Umar
- Bashlachev Andrey
- Bassuni Majid
- Bàmbina Fabrizio
- Bellato Vittoria
- Belli Andrea
- Bensaad Ahmed
- Berchtold Valeria
- Bernante Paolo
- Bertels Laurie
- Beshir Hatem
- Bhatt Nikita
- Bogdan Stoica
- Bonci Eduard-Alexandru
- Borasi Andrea
- Botros Ibram
- Botteri Emanuele
- Bouchrika Amal
- Boukorou Garyfallia
- Brahmachari Swagata
- Bruzzaniti Placido
- Calik Bulent
- Calvo Mikel Prieto
- Campagnaro Tommaso
- Campanelli Michela
- Campennì Paola
- Canfora Alfonso
- Capizzi Vita
- Carrano Francesco Maria
- Castaldi Antonio
- Cavallaro Giuseppe
- Chacón Mario Franco
- Charalabopoulos Alexandros
- Cherfa Harieche Abdennour Abderahim
- Chiarella Vito
- Chipaila Jackson
- Cianci Pasquale
- Cillara Nicola
- Cirillo Bruno
- Ciubotaru Cezar
- Colás-Ruiz Enrique
- Colleoni Ramiro
- Colombo Francesco
- Coniglio Denise
- Costanzo Federico
- Cuk Vladica
- Curtis Nathan
- Dagorno Claire
- Daibes Adel Goda Hussein
- Danilov Michail
- Dare Julius Kolajo
- Daudi Irfan
- Davies Justin
- Dawdi Salahaldeen
- De Falco Nadia
- De Fatico GSerena
- De La Hermosa Alicia Ruiz
- De Lucia Francesca
- De Sousa Xavier
- Del Muslim Ka
- Demeester Steve
- Depuydt Martijn
- Dere Ümit Akın
- Derinov Aleksandr
- Di Bartolomeo Alessandro
- Di Carlo Sara
- Di Lorenzo Nicola
- Di Martino Marcello
- Di Saverio Salomone
- Diamantopoulou Angela
- Díaz Andrés Vega
- Díaz Jeancarlos J. Trujillo
- Doerner Johannes
- Dogjani Agron
- Don Cristine
- Duran Erik Efrain Sosa
- Durayb Norah
- Dursun Ayberk
- Dziakova Jana
- Echevarria Miguel Jose Pinto
- Edassy Mohammed El
- Efetov Sergey
- Eke Grace
- El-Hussuna Alaa
- El-Wakeel Ayman
- Elalfy Khaled
- Elbahrawy Aly
- Elbatal Amira Alsayed Abdelhai
- Eldeeb Ahmed
- Eldemery Mohamed
- Eldesouki Mohammed Nabil
- Eldesouky Omnia
- Eleshra Ahmed
- Elfeki Hossam
- Elgaly Maher Elesawi Kamel
- Elgamal Hesham
- Elganash Abdelazim
- Elgazar Amr
- Elgazar Elsayed Aly
- Elgendy Hesham
- Elghadban Hosam
- Elhafez Raheem El-Gohary Abd
- Elhattab Ahmad
- Elhawary Ahmed Adel
- Elkafoury Ahmed
- Elkased Ahmed Farag
- Elkatt Mahmoud Mohamed
- Elkhouly Ahmed G.
- Elmesery Mohamed
- Elmetwally Ashraf S.
- Elmoghazy Mohamed Ibrahim
- Elnaghi Hisham
- Elnakash Ahmed Mostafa
- Elnemr Islam
- Elnour Ahmed Abd Elbaset Elsayed Abu
- Elrefai Mohamad
- Elsaied Adham
- Elsanhoury Kareem
- Elsanosi Abdelrhman Azhari Mohammed
- Elsayed Mohamed Abdelmoneim
- Elsayed Mohamed Ahmed Abdelhalim Ahmed
- Elseberbihy John Rezk Hanna
- Elshaer Ahmed Mohammed
- Elshazli Mostafa
- Elsheik Ahmed
- ElSheikh Ahmed M.
- Elsherbiny Osama
- Elshikh Essam
- Elsorogy Mohamed
- Elvira Tartaglia
- Elzayady Hany M.
- Elzayat Ibrahim
- Elzeftawy Shady Ahmed
- Emile Sameh Hany
- Enad Farazdaq
- Epifani Angelo Gabriele
- Eral Burak
- Ezz Ahmed
- Fadel Bashir A.
- Fahiem Andrew
- Fakhr Ibrahim
- Falaschi Federica
- Familiari Pietro
- Farag Mohamed
- Farid Ahmed Mohammed
- Farid Mohamed
- Farouk Mohamed
- Farouk Nehal
- Fathy Mohammad
- Fatima Tauseef
- Fawzy Ahmed
- Faye Papa Mamadou
- Fayed Mohamed Abdelaziz Mohamed Abdalla M
- Fazli Mohammad Rafi
- Felix Marcos José Serrato
- Ferrara Francesco
- Ferrario Luca
- Ferri Lorenzo
- Fieturi Nura Ahmed
- Fikry Mohamed
- Fiore Antonio
- Flores Manuel SSalas
- Foppa Caterina
- Fouad Amgad
- Franceschilli Marzia
- Fransvea Pietro
- Frasson Matteo
- Frauenfelder Claire
- Frazzetta Giuseppe
- Freitas Carla
- Frigerio Isabella
- Frontali Alice
- Gaarour Osama
- Gabr Mohamed A.
- Gad Hamada
- Galala Ahmed
- Gallo Gaetano
- Gamal Ehab
- Gamal Sameh
- Ganau Mario
- Garino Mauro
- Garmanovs Tatiana
- Garoufalia Zoe
- Garreffa Emanuele
- Gazia Carlo
- Gehwolf Philipp
- Gendy Samuel Elkess Morcos
- George Ihediwa
- Ghabisha Saif Ali
- Ghafoor Tariq
- Ghanem Ahmed
- Gharbia Mohamed
- Ghazala Mohamed Jomma
- Ghonim Mostafa
- Ghunaim Mohammed
- Giani Alessandro
- Giardino Alessandro
- Giarratano Gabriella
- Giuffrida Maria Carmela
- Giugliano Marco
- Golea Smain
- Gomez Caroina Gonzalez
- Gondal Zafar
- Gonzales Erick Ivan Huaman
- Gorin David
- Gots Alexander
- Grappelli Virgilio Michael Ambrosi
- Guaitoli Eleonora
- Guerci Claudio
- Guerrero José Eaazim Flores
- Guida Anna
- Gulcu Baris
- Gurung Binay
- Haddad Feras
- Hadi Sabah Anwar
- Hamdi Salah
- Hamed Esmael Ali
- Hamed Hosam
- Hamed Mohamed Korayem Fattouh
- Hammad Muhammed Alaa Moukhtar
- Hamza Ahmed
- Hanif Muhammad Amir
- Hasani Ariola
- Hassan Mohamed Ali Gad
- Hassan Mohamed Salah Eldin
- Hassan Redan
- Hatm Mohamed
- Haydal Ashraf
- Hegazy Mostafa
- Hejazi Soha
- Helal Mohamed Alaa Abdelmoez
- Helmy Ahmed Hazem I.
- Hemidan Ahmed Gamal Abouelfetouh Ibrahim
- Henes Mohsen Michael
- Hesham Hosai Todd
- Hijazi Bilal Ahmed
- Hilling Denise
- Holubar Stefan D.
- Hussain Marwah
- Hussein Abdinafic Mohamud
- Ibrahim Ahmed
- Ibrahim Hamed
- Ibrahim Yaser
- Ibrahim Yassin
- Ignatov Ivan
- Ilkul Jh.
- Inam Aatif
- Inama Marco
- Ioan Tanase
- Ioannidis Argyrios
- Iossa Angelo
- Ippoliti Simona
- Isaiah Isaac A.
- Isci Sevim
- Islam S. M. Nazmul
- Ismail Ahmed Mahmoud Ahmed
- Izzo Giuliano
- Jain Amita
- Jallad Fadi Sami
- Jaman Ismail
- Jameel Muhammad Khurram
- Japhet Ntezamizero
- Jarboa Lutfi
- Jarvis Bennie L.
- Jasso Manuel Meza
- Javed Ayesha
- Jawad Fassi Fihri Mohamed
- Jeffery James
- Jolayemi Edward
- Jooma Uzair
- Juloski Jovan
- Junaid Sheikh
- Kaldarov Ayrat
- Kandel Mohamed Mosaad
- Karbovnichaya Elena
- Kassem Amr
- Kateb Abdullah
- Kaur Mandeep
- Kaya Tayfun
- Kazachenko Ekaterina
- Kazim Shuiab
- Kerawala Asad Ali
- Kewulere Raji Taofiq
- Khadwardi Faisal
- Khafagy Tamer
- Khafagy Wael
- Khalaf Mohsen George
- Khalil Medhat M. H. A.
- Khan Irfan Jan
- Khan Roaa Ghazi
- Khare Ritu
- Khashshan Sohib Mohammed Mohammed
- Khawar Mahwish
- Khoj Mohammed
- Khokhar Muhammad Imran
- Khudhayr Essa
- Khuller Somyaa
- Kilinc Gizem
- Kırmızı Yasemin
- Kiselev Michail
- Kitsenko Yury
- Klein Mads Falk
- Koc Mehmet Ali
- Koirala Dinesh Prasad
- Kostakis Ioannis D.
- Kress Melissa
- Kropshofer Stephan
- Kumar Sanjeev
- La Torre Filippo
- Laina Juan Luis Blas
- Lakshmi Harish Neelamraju
- Landaluce-Olavarria Aitor
- Lapolla Pierfrancesco
- Larbi Noureddine
- Lateef Nawras Falah
- Lathan Sanaz
- Lawal Bashir
- Lederhuber Hans
- Lelpo Benedettao
- Leo Cosimo Alex
- Leventoğlu Sezai
- Lewis Sophia
- Liakakos Theodore
- Light Alexander
- Lisi Giorgio
- Litta Francesco
- Lotfy Ahmad
- Loukil Issam
- Luc Jessica G. Y.
- Lule Herman
- Lund Jon
- Lutfi Basma Waseem
- Machairas Nikolaos
- Madbouly Khaled
- Madhuri Thumuluru Kavitha
- Maffioli Anna
- Maghrebi Houcine
- Mahadel Osama Abdel Salam
- Majeed Mudassar
- Majid Haroon Javaid
- Makasarwala Murtaza
- Malek Amgad Nashaat Abdel
- Malibary Nadim
- Maliki-Alaoui Mohamed
- Manetti Andrea
- Mangiameli Giuseppe
- Mansour Khaled Yousery Ibrahim
- Marafante Chiara
- Marano Alessandra
- Marcos Alberto
- Mariani Aurora
- Mariani Nicolò Maria
- Mariateresa Grasso
- Marino Marco V.
- Marra Angelo Alessandro
- Marsanic Patrizia
- Martin Linda W.
- Martin-Perez Beatriz
- Martinelli Fabio
- Marzouk Ahmed Msm
- Marzouk Khalid
- Matarangolo Antonio
- Maurizi Angela
- Mazingi Dennis
- Mbatani Nomonde
- Mbiine Ronald
- Mccaul Jeannie
- Mcnamara Deborah
- Medkova Iuliia
- Mehr Asma
- Mehraj Asif
- Mejdane Abdelhadi
- Menna Maria Paola
- Metwally Mohamed
- Mikhael Marolla Maher Eskander
- Mikrish Amir
- Milad Nader
- Milana Flavio
- Milford Karen
- Milic Ljiljana
- Millan Monica
- Mingoli Andrea
- Minoldo Javier
- Mirza Mohammad Amin
- Mitul Ashrarur Rahman
- Moeslein Gabriela
- Mohamed Mohamed Mohamed Adel
- Mohamed Anwar Yahya A.
- Mohamed Omnia Y.
- Mohammad Mohammad Aminu
- Mohammed Khalid Fathelrahman Bakier
- Mohammed Mahfoudh
- Mohammed Mahmoud M.
- Mohammed Mohammed Mustafa Hassan
- Mohammed Ouazni
- Mohmmed Mona Mhmoud
- Molena Daniela
- Montalbán Beatriz Cros
- Monti Alessio
- Montuori Mauro
- Mora-Guzmán Ismael
- More Vinal
- Morini Andrea
- Moustafa Mohammad Montaser Hassan
- Mpaili Eustratia
- Mubarak Ashraf Abdelazeem Mohamed
- Mudawi Ishag M.
- Muhammad Aneeqah Din
- Muresan Mihai-Stefan
- Mussa Haidar Aal
- Musthafa Shameel
- Nabeeh Mohamed Adel
- Nabil Tamer
- Nabwana Ambrose
- Nadeem Munawar
- Nadeem Uqba
- Nageeb Ashraf
- Nageeb Ramy Mikhael
- Najm Ghadah
- Nakazwe Mildred
- Nasef Hazem
- Nasir Muhammad
- Ndong Abdourahmane
- Negida Ahmed
- Negoi Ionut
- Nekhala Islam
- Ng Hwei Jene
- Ng Jen Siang
- Niaz Khurram
- Nimir Nessrein
- Ninkovic Marijana
- Nittala Rigved
- Njau Aidan
- Njokanma Iloba Gabriel
- Njoroge Githu
- Novikova Anastasia
- null null
- Obadiel Yasser Abdurabo
- Obure Ralph Ombati
- Ocklind Miranda E. K.
- Odion Clement
- Okunlola Abiodun Idowu
- Oludara Mobolaji Adewale
- Oluwasuyi Ige
- Oluyomi Ayodele Samuel
- Omar Mohamed I.
- Omar Tilioua
- Oosthuizen Pj
- Orecchia Luca
- Orlando Francesco
- Osman Khalid Abdalla Abdelgadir
- Osman Luqman
- Ouadii Mouaqit
- Oyedepo Charles Olajide
- Paci Marco
- Pagano Gianluca
- Pakula Andrea M.
- Palkhi Yusuf
- Pandey Diwakar
- Papadopoulos Georgios
- Parello Angelo
- Parente Alessandro
- Parida Lalit
- Pata Francesco
- Peediyakkal Saidalavi Padinhare
- Pellino Gianluca
- Perra Teresa
- Petagna Lorenzo
- Pérez-Bertólez Sonia
- Picciariello Arcangelo
- Pignatelli Marcello Filograna
- Pinotti Enrico
- Pio Luca
- Pirovano Riccardo
- Pirozzi Brunella
- Pitoni Ludovica
- Pohl Linda
- Ponholzer Florian
- Popoola Ademola
- Porcu Alberto
- Portela Carlos Antonio Sanchez
- Pouwels Sjaak
- Prodromidou Anastasia
- Puerto Puerto Alejandro
- Puzenko Dmitriy
- Quesada Matias
- Qurashi Kamran
- Qureshi Ahmad Uzair
- Rabea Mohamed
- Rachid Mohamed Ghassane
- Rao Satish
- Raptis Dimitri
- Rashid Arshad
- Rashid Shahid
- Ratto Carlo
- Rayamajhi Shreya
- Raza Muhammad Asif
- Rea Lo Dico
- Regal Samer
- Rho Maurizio
- Rihan Eslam
- Rimonda Roberto
- Rizk Tarek Taher
- Robles Eloy Morasen
- Rodimov Sergey
- Romic Ivan
- Roscio Francesco
- Rottoli Matteo
- Rubio-Perez Ines
- Ruiz Luis Angel Garcia
- Saad Ahmad
- Saadeldin Abdelhalim
- Saber Wael
- Sabet Khaled
- Sacchi Matteo
- Saeed Muhammad Ahmad
- Sahnan Kapil
- Said Khalid Babieker
- Saklani Avanish
- Sakr Ahmad
- Saleh Amr
- Salem Eman Abdalla Mohamed
- Salem Mohamed Abouelmagd
- Salim Mohammed Said Mahmoud
- Salim Omer El Faroug H.
- Salim Sami
- Sallam Ibrahim
- Salman Usama
- Samadov Elgun
- Samaha Mahmoud Yahia
- Sanad Aly
- Sanad Mohammed
- Santos Esther Garcia
- Santurro Letizia
- Sapienza Paolo
- Sarhan Fetoh Alaaeldin Fetoh
- Sarmah Panchali
- Sasia Diego
- Sauri Fozan
- Sayouh Mohammad
- Sbaih Mohammed
- Scafa Anthony Kevin
- Schuldes Alejandro Daniel Lira
- Sciaudone Guido
- Sebelik Merry
- Seiam Moham
- Selvaggi Francesco
- Sembawa Hatem A.
- Semilan Anmar
- Senent-Boza Ana
- Senra Fatima
- Sergeevich Kochetkov Viktor
- Shafique Muhammad Salman
- Shah Rahmat Ullah
- Shah Shahzad Alam
- Shaheen Abelnasser
- Shahein Mostafa
- Shahin Yasser
- Shaikh Abdul Razaque
- Shaker George Samir Habib
- Shalaby Mostafa
- Shams Maher
- Sharaf Hesham
- Sharafeldin Hatem Abdelrahman Ahmed
- Sharma Meenakshi
- Shawer Sami
- Shawer Sherif
- Shehata Mina
- Shemes Ayman
- Sherbiny Kareem El
- Sherif Ahmed Elshawadfy
- Shetiwy Mosab
- Shittu Asimiyu Adekunle
- Shomoye El-Zaki
- Sibiany Abdulrahman
- Siboe Mark M. W.
- Sidorova Lyudmila
- Sileri Pierpaolo
- Silva Jesús
- Simioni Andrea
- Sindy Abdullah
- Singh Baljit
- Siragusa Leandro
- Situ Oladele
- Skandalakis Georgios P.
- Slavchev Mihail
- Sleilati Fadi
- Sobh Mohamed Ramadan
- Sofan Mostafa
- Soggiu Fiammetta
- Sokmen Selman
- Soliman Ahmed
- Spinelli Antonino
- Spolverato Gaya
- Ssenono Kavuma Daniel
- Stanislav Berelavichus
- Stavrou George
- Stijns Jasper
- Styliani Vasileiadou
- Subramanian Sivaraman
- Suliman Omar AAbu
- Tabasi Hani
- Tagg Gamal Hassan El
- Tairab Elsanousi Ibrahim Sabir
- Taki-Eldin Ahmed
- Tallon-Aguilar Luis
- Taman Mohamed
- Tamburrini Alessandro Paolo
- Tamini Nicolò
- Tanda Cinzia
- Tarabay Ahmed
- Tashkandi Wail
- Tashkandi Waleed
- Tecchio Piero
- Tejedoe Patricia
- Tesik Philip
- Testa Valentina
- Thakrar Dixa
- Thein Nyan
- Tohamy Aley Eldin
- Toma Omar
- Tong Kin Seng
- Torky Radwan Abdelsabour
- Towfigh Shirin
- Troci Albert
- Tropeano Francesca Paola
- Tsounaki Efthymia
- Tuncer Korhan
- Turrado-Rodríguez Víctor
- Uccelli Matteo
- Ugarte-Sierra Bakarne
- Uggeri Fabio
- Uraiqat Ahmad
- Uranitsch Stefan
- Uslu Gülberk
- Valente Marina
- Valery Nekoval
- Van Daele Elke
- Van Praet Charles
- Van Ramshor Gabrielle H.
- Vanlander Aude
- Vanommeslaeghe Hanne
- Varma Gopala Pillay
- Vázquez-Melero Alba
- Vella Ivan
- Veltri Marco
- Venturelli Paolina
- Vikrantmr Sharma
- Villwock Jennifer
- Visconti Diego
- Vishwakarma Kushagra
- Vosloo Susan
- W Njoroge P.
- Waleed Aasma
- Wali Zubair
- Waqar Shahzad Hussain
- Warusavitarne Janindra
- Waseem Talat
- Wexner Steven
- Wuraola Funmilola Olanike
- Yacir El Alami
- Yakar Fatih
- Yanaga Katsuhiko
- Yassin Nouf
- Yassine Wassim Abou
- Yeşilyurt Değercan
- Yildiz Alp
- Yousef Yousef Mohamed
- Youssef Mohamed
- Youssef Youssef Abdel Aziz
- Yves Van Nieuwenhove
- Zafar Noman
- Zahra Tarek
- Zaidi Mariam
- Zaieem Mohammad
- Zakaria Hazem M.
- Zakharenko Alexander
- Zancana Giuseppa
- Zentar Aziz
- Zese Monica
- Zewar Karem Shahin Mohamed
- Zidan Ahmed Azmy
- Zigiotto Daniele
- Zubayraeva Albina
- Zuhdy Mohammad
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020
Screening of exon 11 of BRCA1 gene using the high resolution melting approach for diagnosis in Moroccan breast cancer patients
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study
- Author
- Abdarahman Rabee
- Abdeen Aya
- Abdelmonam Dalia
- Abelazeez Mohamed
- Adams Desiree
- Adegnika Ayola Akim
- Adewole Olufemi
- Agodokpessi Gildas
- Ahmed Rana
- Ahmed Syed Masud
- Aikman Althea Akosua Francia
- Ait-Khaled Nadia
- Akmatalieva Meerim
- Al Ghobain Mohammed
- Al Hajjaj Hajjaj
- Aliko Anila
- Almeda Rosel
- Almeida João
- Alorainy H.
- Altaher Hoyam
- Amaral Andre F.S.
- Amarillo Lourdes
- Amor Caron
- Aquart-Stewart Althea
- Argade Rupali
- Ashu Atongno Humphrey
- Atoui Feryal
- Awopeju Olayemi
- Ayelo Paul
- Ayuyao Fernando G.
- Azar Hadia
- Azilova Toktogul
- Balanag Vincent M.
- Banal-Yang Sylvia
- Banda Gloria
- Banda Justice
- Bardhi Donika
- Barnes Edward
- Bateman Eric
- Beishekeeva Gulnara
- Benali Rachid
- Bencheikh Abdelghani
- Benedikdtsdottir Bryndis
- Bengrait Amira
- Benjelloun Mohamed C.
- Berratio Lakan U.
- Bird Tessa
- Bodemann Isabelle
- Bondre Suvarna
- Bostonova Eliza
- Boudra Soumaya
- Boukheroufa Zaki
- Brashier Sundeep Bill
- Buist A. Sonia
- Burney Peter G.J.
- Bárbara Cristina
- Cain John
- Cardoso João
- Chaidhary Bharat
- Chatterjee Sukantha Kumar
- Chaudhary Sharda
- Cherkaski Hamid Hacene
- Chipeta Martha
- Chouikha Firas
- Chowdhury Tridib Roy
- Chowgule Rohini
- Conyette Liane
- Copeland Rebecca
- Crapo Robert
- Cullinan Paul
- Daldoul Hager
- Dantes Renato B.
- Das Shyamal Chandra
- Dawes Torkil
- de Guia Teresita S.
- De Matteis Sara
- Dela R.
- Denguezli Meriam
- Devchakke Sampada
- Dhanawade Rupesh
- Dias Hermínia
- Doloriel E.
- Dononbaeva Nasyikat
- Dudhaiya Risha
- ed Elhassan Namarig Moham
- El Rhazi Karima
- El Zain Abdel Mu'is
- El-Hamad E.
- Elbiaze Mohamed
- Elhadi Mahmoud
- Elsadig Hana A.
- Elsony Asma
- Eltayeb Roa
- Eltigani Hind
- Emilov Berik
- Endresen Tina
- Enright Paul
- Erhabor Gregory
- Espinel Paola
- Estebesova Bermet M.
- Fanuncio R.
- Fatmi Zafar
- Fayomi Benjamin
- Fernandez Lenora C.
- Ferreira Reis
- Francisco Norberto A.
- Franssen F.F.E.
- Freeman Jasper
- Frey Jakub
- Gaikwad Vijay
- Garcia Gerard S.
- Gawhane Ashleshsa
- Geldmacher Henning
- Ghit Maamar
- Ghurup Umesh
- Gillespie Suzanne
- Gislason Thorarinn
- Gnatiuc Louisa
- Gudmundsdottir Lovisa
- Gudmundsdottir Sigrun
- Gulsvik Amund
- Gunasekera Kirthi
- Gundmundsson Gunnar
- Haddad Tabarek
- Hafizi Hasan
- Hakim Nissar A.
- Hancioglu Attila
- Hanta Ismail
- Haram NN
- Harat Rafal
- Hardaker Kate
- Harrabi Imed
- Hashi A.
- Hassan Mohand
- Hayes Anton
- Hazen Dana
- Hirve Siddhi
- Hlengwa Sipho
- Hägg Gunilla
- Idolor Luisito F.
- Iqbal Meesha
- Irfan Muhammad
- Islam Akramul
- Islam Maidul
- Islam Nazrul
- Islam Nurul
- Islam Qazi Shafayetul
- Islam Shayla
- Ismaeel Rimaz
- Janson Christer
- Jenkins Christine
- Jensen Robert L.
- Jithoo Anamika
- Jogi Rain
- Johannisen Christine
- Juvekar Sanjay
- Jörundsdottir Kristin
- Kadam Milind
- Kamal Rashid
- Kambwili Mayamiko
- Katkar Sunil
- Kazasi Rezarta
- Khalifa Suhaiba
- Khalifa Wahbi Belhaj
- Khan Abdul Awal
- Khan Umar Hafiz
- Khatun Luiza
- Kocabaş Ali
- Koopman Mariana
- Koul Parvaiz A.
- Kpangon Arsene
- Kpossou Karl
- Kuleci Sedat
- Kydyrova Jypara
- Laja Hendrik
- Lamprecht Bernd
- Lawin Herve
- Lee Todd A.
- Lill Toomas-Julius
- Liu Shengming
- Loh Li Cher
- Londhe Jyoti
- Louw Innocentia
- Lu Jiachun
- Ludick Ina
- Lund Gun-Marie
- Lutchmansingh Fallon
- Madas Sapna
- Mahesh Padukudru Anand
- Malik Sajjad
- Mannino David M.
- Marajapov Nuridin
- Marciano I.
- Marks Guy
- Matos Maria João
- Mbatchou Bertrand
- McBurnie Mary Ann
- McLean Fiona
- Mejza Filip
- Mesbah-Ul-Haque NN
- Methvin Jennifer
- Mezini Arian
- Mia Dulal
- Mkandawire Suzgo
- Mohamaden Marwa Mohamed
- Mohamed Lina
- Mohamed Malaz
- Mohamed Monjda Awad
- Mohamed Rayan
- Mortimer Kevin
- Mwangoka Ernest
- Nafees Asaad A.
- Nastalek Pawel
- Naval Sullian S.
- Nejjari Chakib
- Nielsen Rune
- Nikolla Jolanda
- Nisser Katarina
- Nizankowska-Mogilnicka Ewa
- Noory Bandar Salah
- Obaseki Daniel O.
- Olafsdottir Inga Sif
- Olckers Alta
- Osman Hasab Alrasoul Akasha Ahmed
- Osman Mihad
- Osman Nada Bakery
- Pajak Andrzej
- Parvin Monira
- Patel Jaymini
- Pingale Savita
- Potts James
- Rahman Mizanur
- Ran Pixin
- Raphael Jonelle
- Rashid Abdul
- Ratanachina Jate
- Reyes Maria Teresita N.
- Reyes Thessa
- Roa Camilo C.
- Roa Camilo C.
- Rodrigues Fátima
- Roubhia Abdelhamid
- Ryck Johanna
- Safia L.
- Salvi Sundeep
- Sambhudas Somnath
- Sanchez Ma. Flordeliza
- Santos Moutinho
- Sapkal Anil
- Schirhofer Lea
- Schweda-Linow Alexandra
- Seemungal Terence
- Shaukat Natasha
- Shelar Nitin
- Sheraliev Ulan
- Shetye Vasant
- Sholehah Siti
- Simpao Leander P.
- Simão Paula
- Skucha Wojciech
- Sooronbaev Talant M.
- Spetz-Nyström Ulrike
- Storbeck Janita
- Studnicka Michael
- Sullivan Sean
- Svendsen Lene Løvendahl
- Szczeklik Andrzej
- Tabka Zouhair
- Tabyshova Aijamal
- Tadvi Rafiq
- Tady Cecil Z.
- Tafa Holta
- Tambe Meera
- Tan Daniel T.
- Tan Wan C.
- Tawde Mahesh
- Teferici Alma
- Thanasi Natasha
- Todri Dafina
- Toelle Brett
- Toktogulova Nurgul
- Tumilty Michael
- Turkyilmaz Ahmet Sinan
- Twardowska Magda
- Uddin Shahaz
- Ulst Katrin
- Umap Arati
- Umap Archana
- Umar Stephen's
- Umut Sema
- Unalan Turgay
- Usenbaeva Saadat
- Vollmer William M.
- Walke Savita
- Wang Dali
- Wang Wen
- Weiss Kevin B.
- Welte Tobias
- Wesseling G.J.
- Wickremasinghe Rajitha
- Wouters Emiel F.M.
- Yakoubi Randa
- Zahidie Aysha
- Zgaoula Ibtissem
- Zheng Jinping
- Zhong NanShan
- Zhou Yumin
- Zobel Vappu
- Publication venue
- European Respiratory Society
- Publication date
- 01/01/2023
- Field of study
Background
Chronic obstructive pulmonary disease has been associated with exposures in the workplace. We aimed to assess the association of respiratory symptoms and lung function with occupation in the Burden of Obstructive Lung Disease study.
Methods
We analysed cross-sectional data from 28 823 adults (≥40 years) in 34 countries. We considered 11 occupations and grouped them by likelihood of exposure to organic dusts, inorganic dusts and fumes. The association of chronic cough, chronic phlegm, wheeze, dyspnoea, forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1)/FVC with occupation was assessed, per study site, using multivariable regression. These estimates were then meta-analysed. Sensitivity analyses explored differences between sexes and gross national income.
Results
Overall, working in settings with potentially high exposure to dusts or fumes was associated with respiratory symptoms but not lung function differences. The most common occupation was farming. Compared to people not working in any of the 11 considered occupations, those who were farmers for ≥20 years were more likely to have chronic cough (OR 1.52, 95% CI 1.19–1.94), wheeze (OR 1.37, 95% CI 1.16–1.63) and dyspnoea (OR 1.83, 95% CI 1.53–2.20), but not lower FVC (β=0.02 L, 95% CI −0.02–0.06 L) or lower FEV1/FVC (β=0.04%, 95% CI −0.49–0.58%). Some findings differed by sex and gross national income.
Conclusion
At a population level, the occupational exposures considered in this study do not appear to be major determinants of differences in lung function, although they are associated with more respiratory symptoms. Because not all work settings were included in this study, respiratory surveillance should still be encouraged among high-risk dusty and fume job workers, especially in low- and middle-income countries.publishedVersio
Global economic burden of unmet surgical need for appendicitis
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- Aahlin E. K.
- Aamer A.
- Aaniana K.
- Ababneh A.
- Abaliksta T.
- Abantanga F.
- Abbas M.
- Abbasy J.
- Abbo O.
- Abbouch M.
- Abd-Elmawla M.
- Abd-Elrasoul Y.
- Abdallah E.
- Abdel-Aty A.
- Abdel-Hameed N.
- Abdel-Kader S. M.
- Abdel-Wahab N. Y. E.
- Abdelaal A.
- Abdelaty M.
- Abdelazeam A. R.
- Abdelazim G.
- Abdelaziz M. A.
- Abdelbadeai K.
- Abdelfatah A.
- AbdelFattah I.
- Abdelgelil A.
- Abdelghany S.
- Abdelhady S.
- Abdelhamed R.
- Abdelhamid A.
- Abdelhaq A.
- Abdelkader M.
- Abdelkader O.
- Abdelkareem A.
- Abdelkhalek M.
- Abdelmageed E.
- Abdelmotaleb I.
- Abdelraheim M.
- Abdelraouf A. M.
- Abdelrouf D. M.
- Abdelshafy M.
- Abdelshakour M.
- Abdrabou A. K.
- Abdul-Latif S.
- Abdulaziz H.
- Abdulbagi O.
- Abdulgawad M.
- Abdulhakeem E. M.
- Abdullah M. A.
- Abdullah N.
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- Weber P.
- Weiser T. G.
- Wheeler J.
- Whitaker J.
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- Whitehurst K.
- Wiborg J.
- Widiastini T. A.
- Wild J. R. L.
- Williams O.
- Wilson L.
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- Wredberg C.
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- Yang J.
- Yaseen T.
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- Yavuz M. A.
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- Yeang L. J.
- Yeo L. S.
- Yeung M. H. A.
- Yifieyeh A.
- Yip C.
- Yip S. B. S.
- Ymeri S.
- Yoganathan P.
- Yong C. O.
- Yong G. L.
- Youssef D.
- Youssef H.
- Youssef M.
- Youssif J. H.
- Yuksek M. A.
- Yusufali T.
- Zaa'treh R.
- Zachariades D. -C.
- Zadoroznas A.
- Zahran D.
- Zakaria E.
- Zakaria M.
- Zakaria Y.
- Zaki A.
- Zalabia M. F.
- Zamarin K.
- Zammit S.
- Zampitis N.
- Zani A.
- Zanini N.
- Zapata F.
- Zarb C.
- Zardab A.
- Zegarra S.
- Zerihun A. B.
- Zhang Z.
- Zheng F.
- Zidan H.
- Zidan M.
- Ziff O.
- Zil-E-Ali A.
- Zilinskas J.
- Zilinskiene R.
- Ziubryte G.
- Zohair A.
- Zuber M.
- Zulkifli A.
- Publication venue
- Oxford University Press
- Publication date
- 01/01/2022
- Field of study
Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
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- Aamer A
- Aaniana K
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- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahmy MAB
- Fahy C
- Fairfield C
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- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat MM
- Faraz A
- Fares M
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- Farhan-Alanie MMH
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
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- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
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- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald JE
- Fitzgerald JE
- Florez Farfan ES
- Foco M
- Fok CYJ
- Fontana T
- Foo CC
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- Forno W
- Fouad A
- Fouad D
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- Fowler AJ
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- Fozard T
- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
- Gad A
- Gad MO
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaignard E
- Gaignard E
- Gaizauskas V
- Gala T
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- Galiqi G
- Galleano R
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- Galvez CP
- Gamal D
- Gamal E
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- Garcia Bernardo C
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- Gemeah M
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- Gerosa A
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- Ghaben A
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- Halicioglu I
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- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Cohort Profile: Burden of Obstructive Lung Disease (BOLD) study
- Author
- Aardal Marit
- Abass Najlaa Mohamed
- Abdelmonam Dalia
- Adams Desiree
- Adewole Olufemi
- Agarwal Dhiraj
- Agodokpessi Gildas
- Agrawal Dhiraj
- Ahmed Ahmed Beriar
- Ahmed Rana
- Ahmed Rana
- Aikman Akosua Francia
- Ait-Khaled Nadia
- Akmatalieva Meerim
- Al Ghobain M
- Al Ghobain Mohammed
- Al Hajjaj M
- AlaElddin Sahar
- Aliko Anila
- Almeda Rosel
- Almeida João
- Alorainy H
- Amaral Andre F S
- Amaral Andre F S
- Amarillo Lourdes
- Amor Caron
- Anand Mahesh Padukudru
- Anand Mahesh Padukudru
- Andrén Mona
- Appelfeldt Birgitta
- Aquart-Stewart Althea
- Aquart-Stewart Althea
- Argade Rupali
- Ashu Atongno Humphrey
- Atoui Feryal
- Atrokpo Rolus
- Awopeju Olayemi
- Ayelo Paul
- Ayuyao Fernando G
- Azar Hadia
- Azilova Toktogul
- Bagkeris Emmanouil
- Bagkeris Emmanouil
- Balanag Vincent M
- Banal-Yang Sylvia
- Banda Gloria
- Banda Justice
- Barbara Cristina
- Bardhi Donika
- Barnes Edward
- Bateman Eric
- Beishekeeva Gulnara
- Benali Rachid
- Bencheikh Abdelghani
- Benedikdtsdottir Bryndis
- Bengrait Amira
- Benjelloun Mohamed C
- Benjelloun Reda
- Berratio Lakan U
- Bird Tessa
- Bodemann Isabelle
- Bondre Suvarna
- Bostonova Eliza
- Boudra Soumaya
- Boukheroufa Zaki
- Brashier Bill
- Buist A Sonia
- Buist A Sonia
- Burney Peter
- Burney Peter G J
- Bárbara Cristina
- Cain John
- Cardoso João
- Chaidhary Bharat
- Chaudhary Sharda
- Chefchaou Yassin
- Cherkaski Hamid Hacene
- Cherkaski Hamid Hacene
- Chipeta Martha
- Chirwa Catherine
- Chouikha Firas
- Chowgule Rohini
- Conyette Liane
- Copeland Rebecca
- Crapo Robert
- Cullinan Paul
- Daldoul Hager
- Dale Gerd Eli
- Dantes Renato B
- Dantes Renato B
- Dawes Torkil
- de Guia Teresita S
- de Guia Teresita S
- Dela R
- Denguezli Meriam
- Denguezli Myriam
- Devchakke Sampada
- Devereux Graham
- Devereux Graham
- Dhanawade Rupesh
- Dias Hermínia
- Doloriel E
- Dononbaeva Nasyikat
- Dudhaiya Risha
- El Rhazi Karima
- El Zain Abdel Mu'is
- El-Hamad E
- Elbiaze Mohamed
- Elhadi Mahmoud
- ElHarche Btissame
- Elhassan Namarig Moham ed
- Elsadig Hana A
- Elsony Asma
- Eltigani Hind
- Emilov Berik
- Endresen Tina
- Enright Paul
- Erdal Marta
- Erhabor Gregory
- Espinel Paola
- Estebesova Bermet M
- Fanuncio R
- Fayomi Benjamin
- Fernandez Lenora C
- Ferreira Reis
- Fleten Hildegunn B
- Francisco Norberto A
- Francisco Norberto A
- Freeman Jasper
- Frey Jakub
- Gagnat Ane Aamli
- Gaikwad Vijay
- Garcia Larsen Vanessa
- Garcia Gerard S
- Garcia-Larsen Vanessa
- Gawhane Ashleshsa
- Gegic Jasleen
- Geldmacher Henning
- Ghit Maamar
- Ghurup Umesh
- Gillespie Suzanne
- Gislason Thorarinn
- Gislason Thorarinn
- Gnatiuc Louisa
- Grøttveit Malin P
- Gudmundsdottir Lovisa
- Gudmundsdottir Sigrun
- Gudmundsson Gunnar
- Gulsvik Amund
- Gunasekera Kirthi
- Haddad Tabarek
- Hafizi Hasan
- Hakim Nissar A
- Hancioglu Attila
- Hanta Ismail
- Haq Roman Ul
- Harat Rafal
- Hardaker Kate
- Harrabi Imed
- Harrabi Imed
- Hashi A
- Hassan Mohand
- Hayes Anton
- Hazen Dana
- Hirve Siddhi
- Hlengwa Sipho
- Hounton Gaston
- Hsan Safa
- Hägg Gunilla
- Idolor Luisito F
- Idolor Luisito F
- Irfan Muhammad
- Janson Christer
- Janson Christer
- Jenkins Christine
- Jensen Robert L
- Jithoo Anamika
- Jithoo Anamika
- Johannisen Christine
- Jonas Frank
- Juvekar Sanjay
- Juvekar Sanjay
- Jõgi Rain
- Jörundsdottir Kristin
- Kadam Milind
- Kale Namdev
- Kambwili Mayamiko
- Kathale Shirish
- Katkar Sunil
- Kazasi Rezarta
- Khalifa Suhaiba
- Khalifa Wahbi Belhaj
- Khan Umar Hafiz
- Kiili Katrin
- Knox-Brown Ben
- Kocabaş Ali
- Kocabaş Ali
- Koopman Mariana
- Koul Parvaiz
- Koul Parvaiz A
- Kpangon Arsene
- Kpossou Karl
- Kuleci Sedat
- Kydyrova Jypara
- Laanelepp Ira
- Laja Hendrik
- Lakhdar Nadia
- Lamprecht Bernd
- Landolsi Mounir
- Lawin Herve
- Lee Todd A
- Lill Toomas-Julius
- Liu Shengming
- Loh Li Cher
- Loh Li-Cher
- Londhe Jyoti
- Louw Innocentia
- Lu Jiachun
- Ludick Ina
- Lund Gun-Marie
- Lutchmansingh Fallon
- Madas Sapna
- Malik Sajjad
- Malinovschi Andrei
- Mannino David
- Mannino David M
- Marajapov Nuridin
- Marciano I
- Marks Guy
- Matos Maria João
- Mbatchou Bertrand
- McBurnie Mary Ann
- McLean Fiona
- Mejza Filip
- Methvin Jennifer
- Mezini Arian
- Mhango Chifundo
- Mhetre Shalan
- Minelli Cosetta
- Minelli Cosetta
- Mjojo Patrick
- Mkandawire Suzgo
- Mohamaden Marwa Mohamed
- Mohamed Monjda Awad
- Mortimer Kevin
- Mortimer Kevin
- Mulhern Octavia
- Mwangoka Ernest
- Nafees Asaad A
- Nafees Asaad Ahmed
- Nastalek Pawel
- Naval Sullian S
- Nejjari Chakib
- Ngwira Edgar
- Nielsen Rune
- Nikolla Jolanda
- Nisser Katarina
- Nizankowska-Mogilnicka Ewa
- Njoroge Martin
- Njoroge Martin
- Noman Muhammad
- Noory Bandar Salah
- Nordeide Eli
- Nyapigoti Wezzie
- Obaseki Daniel
- Olafsdottir Inga Sif
- Olckers Alta
- Osman Hasab Alrasoul Akasha Ahmed
- Osman Nada Bakery
- Osman Rashid
- Pajak Andrzej
- Paraguas Stefanni Nonna
- Paraguas Stefanni Nonna M
- Patel Jaymini
- Pawar Babu
- Pingale Savita
- Potts James
- Potts James
- Pálsdottir Hjördis Sigrun
- Ran Pixin
- Raphael Jonelle
- Rashid Abdul
- Reyes Maria Teresita N
- Reyes Thessa
- Rjimati Manelle
- Roa Camilo C
- Roa Camilo C
- Rodrigues Fátima
- Rotevatn Anders Ørskov
- Roubhia Abdelhamid
- Ryck Johanna
- Rylance Jamie
- Safia L
- Salvi Sundeep
- Sambhudas Somnath
- Sanchez Ma Flordeliza
- Santos Moutinho
- Sapkal Anil
- Schirhofer Lea
- Schweda-Linow Alexandra
- Seemungal Terence
- Seemungal Terence
- Shelar Nitin
- Sheraliev Ulan
- Shetye Vasant
- Sholehah Siti
- Simpao Leander P
- Simão Paula
- Skjelde Åsa
- Skucha Wojciech
- Sooronbaev Talant M
- Spetz-Nyström Ulrike
- Storbeck Janita
- Studnicka Michael
- Studnicka Michael
- Sullivan Sean
- Svendsen Lene
- Szczeklik Andrzej
- Tabka Zouhair
- Tabyshova Aijamal
- Tadvi Rafiq
- Tady Cecil Z
- Tafa Holta
- Tahir Hasan Nawaz
- Tambe Meera
- Tan Daniel T
- Tan Wan C
- Tan Wan C
- Tawde Mahesh
- Teferici Alma
- Thanasi Natasha
- Thorarinsdottir Elin Helga
- Todri Dafina
- Toelle Brett
- Toktogulova Nurgul
- Tumilty Michael
- Turkyilmaz Ahmet Sinan
- Twardowska Magda
- Ulst Katrin
- Umap Arati
- Umap Archana
- Umut Sema
- Unalan Turgay
- Usenbaeva Saadat
- van Zyl-Smit Richard
- van Zyl-Smit Richard N
- Vollmer William M
- Walke Savita
- Wallberg Eva
- Wang Dali
- Wang Wen
- Weiss Kevin B
- Welte Tobias
- Welte Tobias
- Wesseling G J
- Wickremasinghe Rajitha
- Wouters E F M
- Yadjodo Dieudonnè
- Yakoubi Randa
- Zgaoula Ibtissem
- Zheng Jin-ping
- Zhong NanShan
- Zhou Yumin
- Zobel Vappu
- Zumazuma Faith
- Publication venue
- Oxford University Press (OUP)
- Publication date
- 20/10/2023
- Field of study
The Burden of Obstructive Lung Disease (BOLD) study was established to assess the prevalence of chronic airflow obstruction, a key characteristic of chronic obstructive pulmonary disease, and its risk factors in adults (≥40 years) from general populations across the world.
The baseline study was conducted between 2003 and 2016, in 41 sites across Africa, Asia, Europe, North America, the Caribbean and Oceania, and collected high-quality pre- and post-bronchodilator spirometry from 28 828 participants.
The follow-up study was conducted between 2019 and 2021, in 18 sites across Africa, Asia, Europe and the Caribbean. At baseline, there were in these sites 12 502 participants with high-quality spirometry. A total of 6452 were followed up, with 5936 completing the study core questionnaire. Of these, 4044 also provided high-quality pre- and post-bronchodilator spirometry.
On both occasions, the core questionnaire covered information on respiratory symptoms, doctor diagnoses, health care use, medication use and ealth status, as well as potential risk factors. Information on occupation, environmental exposures and diet was also collected
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
- Ampofo William K.
- Amuri Adrienne A.
- Amuzu Dominic S. Y.
- Amzazi Saaïd
- Anang Abraham Kwabena
- Anas Abbad
- Andeko Julia C.
- Andersen Kristian
- Andersson Hana Sofia
- Andika Brian
- Andres Moreira-Soto
- Andriam Soa Fy
- Andriamandimby Soa Fy
- Anga Latifa
- Ange Dossou
- Angelov Angel
- Anna-Lena Sander
- Annajr B.
- Anoh Etilé A.
- Anscombe Catherine
- Antwerpen Markus H.
- Anu Campbell
- Anyaneji Ugochukwu J.
- Anyika Chinyere
- Aouni M.
- Appiah Vincent
- Appiah-Kubi Joyce
- Arena Fabio
- Arjaquah Augustina
- Arjarquah A.
- Armand Edang-Minko
- Armanious Riad Mounir
- Armoo Samuel
- Arnaldo Paulo
- Arnold Catherine E.
- Arrouchi Housna
- Artesi Maria
- Aryeetey Sherihane
- Asamoah Jesse Addo
- Asante Ivy A.
- Asare K.M.
- Ashton Philip
- Ashton Phillip
- Asiedu Ernest
- Asiedu-Bekoe Franklyn Egbe
- Asiimwe Stephen
- Askander Omar
- Asmamaw Kominist
- Assane Hamadi
- Assoumou Samira Zoa
- Atiga N.
- Attiku Keren Okyerebea
- Audu Rosemary A.
- Auld A.
- Awandare Gordon A.
- Awinda George
- Awunyo Sena
- Ayansola Oyeronke
- Ayei James
- Ayekaba Mitoha Ondo’o
- Ayivor-Djanie Reuben
- Aymane Bouzidi
- Ayo-Ale B.
- Ayoade F.
- Ayoola Joy
- Ayouba Ahidjo
- Aziz Ramy Karam
- Aziza Amuri
- Azman Andrew
- Aïssi Melchior A. Joël
- Ba-Diallo Awa
- Babatunde Sunday
- Baboo S. B.
- Badjo Ange
- Badou Yvette
- Bagaya Bernard Ssentalo
- Bah Mamadou Saliou
- Bahadoor B. S.
- Bahnassy A.A.
- Bajjou Tahar
- Baker David
- Baker Noah
- Bakhash Shah Mohamed
- Bakry U.
- Balde Aladje
- Balde Aladje
- Balm Michelle
- Bamourou Diané
- Banda R.
- Bane S.
- Barasa Edwine
- Barbet Marion
- Bareng Ontlametse T.
- Barilar Ivan
- Barkat Amina
- Barnes Kayla
- Barreh Guedi Ali
- Bashein Abdulla
- Bassène Hubert
- Batchi-Bouyou Armel L.
- Batchi-Bouyou Armel L.
- Bates Matthew
- Batra Dhwani
- Batra R.
- Bauer Peter
- Baxter Cheryl
- Bayih Abebe Genetu
- Bbosa Nicholas
- Bedford Trevor
- Bediako Yaw
- Bedié
- Bedri Shahinaz.A.
- Behillil Sylvie
- Bejon Philip
- Belarbi Essia
- Belfquih Bouchra
- Belkhir A.B.
- Bellefquih Abdelkrim Meziane
- Beloufa Mohamed Amine
- Belournou Grace Angong
- Ben Alaya Nissaf
- Ben Ayed I.
- Ben Boubaker Ilhem Boutiba
- Ben Boubaker Ilhem Boutiba
- Ben Kahla Alia
- Ben Khelil Jalila
- Ben Moussa Mohamed
- Ben Othman Roua
- Ben Romdhane Habiba
- Ben Sassi Manel
- Ben Sassi Mouna
- Benaissa Elmostafa
- Benhida Rachid
- Benkeroum Samira
- Benkirane Hasnae
- Bennett Andrew J.
- Benrahma Houda
- Bensaid M.
- Bensalem Aicha
- Benyahia Amel
- Bestehorn-Willmann Malena S.
- Bester Phillip A.
- Beyene Getachew Tesfaye
- Bhiman Jinal N.
- Bighignoli B.
- Bikangui Rodrigue
- Bimouhen Abderrahmane
- Bingono Sam O'neilla Oye
- Biscornet Leon
- Bishop-Lilly Kimberly A.
- Bitew Molalegne
- Bitrou S.M.
- Bizard Méline
- Bióté Simão Tchuda
- Blackmore Timothy
- Blakiston Matt
- Bloomfield Max
- Bnouyahia Ikram
- Boatemaa Linda
- Bolajoko Bankole
- Bonney Evelyn Y.
- Bonney Joseph H. K.
- Bonney Kofi
- Bontems Sébastien
- Bootsma Sacha
- Borrmann Steffen
- Boter Marjan
- Boujemla Bouchra
- Bours Vincent
- Boussoukou Ismael Pierrick Mikelet
- Bouzid Amal
- Bouzid Jawad
- Bracchitta Fiorenza
- Brechar Ludivine
- Bridges Daniel J.
- Briese Thomas
- Brisebarre Angela
- Brook Cara
- Bssaibis Fatna
- Budiaki Sylvie L.
- BUHARI Mikhail Olayinka
- Bulimo Wallace D
- Bunga Sudhir
- Butel Christelle
- Butera Yvan
- Bwogi Josephine
- Camara Alimou
- Camara Makhtar
- Campbell Allan
- Campbell Julian
- Cancino Irving
- Candé Adul
- Capel Camille
- Carey Omondi Francis
- Carniel Elisabeth
- Carr Rosina A. A.
- Carri Valeria Delli
- Carvalho Kevin S.
- Cassama Faatu
- Cedola Donatella
- Cer Regina Z.
- Chabert-Consen Marie Madeleine
- Chabuka L. B.
- Chabuka Lucious
- Chambaro H.
- Chammam Sara
- Chamman Sarra
- Chanda D.
- Changula K.
- Charlene Sonal P.
- Chawech H.
- Chenaoui Mohamed
- Chenwi Collins
- Chestakova Irina
- Chgouri Fatima
- Chilufya C.
- Chilufya Moses
- Chimedza Jasper
- Chinedu Ugwu
- Chipimo P.J.
- Chitanga S.
- Chitechi Esther
- Chitenje M.
- Chiwaula M. J.
- Choga Wonderful T.
- Chouati Taha
- Chouikha Anissa
- Christoffels Alan
- Chtourou A.
- Chukwu Chimaobi
- Chukwu G.
- Cigolo Jean-Claude Makangara
- Cisse Barada
- Clarisse Murebwayire
- Colson Philippe
- Comas Iñaki
- Combe Patrice
- Corman Victor Max
- Cortes Carlos
- Cotten Matthew
- Crawford M.
- Crespin Xavier
- Cá Milanca Agostinho
- D'Amore N.
- D'Aprile Annamaria
- Dadi Hailu
- Daghfous Riadh
- Dagnran Anoumou
- Dakka Hanae
- Dal Monego Simeone
- Damaris Matoke-Muhia
- Damena D.
- Damilari Dabiri
- Daniels Rodney S.
- Dao Sounkalo
- Daou Amadou
- Dara Antoine
- Daubenberger Claudia
- David Kumbelembe
- Davids Micheala
- Davies Mary-Ann
- Dawood R.M.
- Dawood Reham
- de Laurent Zaydah R.
- de Ligt Joep
- De Nittis Rosella
- de Oliveira Filho Edmilson F.
- de Oliveira Martins Leonardo
- de Oliveira Tulio
- De Sanctis R.
- de Silva Thushan I
- DeAlmeida Mary
- Debela Alemu Tike
- Delaney Kayla
- Delaporte Eric
- Delerce Jeremy
- Dellagi Koussay
- Deng Guohong
- Deng Lul Lojok
- DeRisi Joseph L.
- Derrar Fawzi
- Descheemaeker Patrick
- Deschenes Michael V.
- Desta Adey Feleke
- Detweiler Angela M.
- Devatchagni Syntyche
- Devaux Christian A.
- Dhaala Beatrice
- Dia Aminata
- Dia Ndongo
- Dia Yacine Amet
- Diab A.
- Diagne Diabou
- Diagne Moussa M.
- Diakite Mandiou
- Diallo Amadou
- Diallo Haby
- Diallo Penda Malhado
- Diallo Sada
- Diarra B.
- Diarra Bassirou
- Diaw Papa Alassane
- Diawara Idrissa
- Dieng Alle Baba
- Dieng Assane
- Diergaardt Azaria
- Diop Mamadou
- Diop Oumy
- Djimde Abdoulaye
- Djingarey Mamoudou Harouna
- Djomsi Dowbiss Meta
- Djontu Jean Claude
- Dobi Paul
- Donati Flora
- Dorkenoo Ameyo
- Doudou Fetouma
- Douffan Messanh
- Doumbia Seydou
- Draper C.
- Dratibi Fred A.
- Drinkovic Dragana
- Drosten Christian
- Duedu Kwabena O.
- Durkin Keith
- Dussart Philippe
- Dussart Philippe
- Dürr Kouriba
- Ebied Fatma
- Ebong Ofonime
- Eckstein Simone
- Edu Emame
- Eggan Stephen M.
- Egli Adrian
- Egoh Ifunanya
- Egyir B.
- Ehlan Amivi
- El Amin Ghizlane
- El ansari Fatima Zahra
- El Atar Jalil
- El Fahime Elmostafa
- El Falaki Fatima
- El Guindy Nancy M.
- El Hady Yassine
- El Jaoudi Rachid
- El Jebari Hanen
- El Mazouri Safae
- El Mrimar Nadia
- El Sayes Mohamed
- El-Duah Philip
- El-Shaqnqery H.
- El-Shesheny Rabeh
- El-Taweel Ahmed
- El-Zayat M.
- Elahmer Omar
- Elalaoui Mly Abdelaziz
- Elannaz Hicham
- Elarab Hoda Ezz
- Elargoubi A.
- Elfihri Mohammed Walid Chemao
- Elgahzaly Hesham
- Elgohary Mohamed Abdel-Salam
- Elguindy Nancy
- Elhadidi Mohamed
- Elhag Khabab A.
- Elhamoumi Siham
- ElHefnawi Mahmoud
- Elhoseiny Mostfa
- Elhoseny M.M.
- Elhosieny F.W.
- Elisabeth Carniel
- Elkhateeb S.M.
- Elkochri Safae
- Ella Kevine Zang
- Ellis Sean
- ElMoussi Awatef
- Elnakib Mostfa
- Eloualid Mjid
- Elouanass M.
- Elouennass Mostafa
- Elroby Ola
- Elsaid Manal Hamdy
- Elsawy Laila
- Elsayed Ahmed
- Elshora Hagar
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- Elvy Juliet
- Elzagheid Adam I.
- Embaló Bubacar Delgado Pinto
- Emna Gaies
- Emokpae Uyi
- Enatha Mukantwari
- Endjala Nathalia
- Engelbrecht Susan
- Ennibi H.
- Enouf Vincent
- Erameh Cyril
- Erhart Annette
- Eshun Miriam
- Essabbar Abdelomunim
- Essabbar Mouneem
- Essayagh Touria
- Essomba René G.
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- Estrella Luis A.
- Everatt Josie
- Exler Jan Felix
- Ezzelarab M.H.
- Fadeyi Abayomi
- Fageer Sameira M.
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- Faggioni G.
- Fahsbender E.
- Fainguem Ndine
- Faisal Muhammad
- Fakayode Oluwatosin
- Fakhfakh Ahmed
- Fall Mbengué
- Faouzi Abdellah
- Faouzia Zemmouri
- Farawyla H.
- Fares Wasfi
- Farghaly Ayman
- Faye Martin
- Faye Ousmane
- Feasey Nicholas
- Fedorov A.V.
- Fekkak Jamal
- Femi Ayoade
- Femi Oladiji
- Femi Saibu
- Fenollar Florence
- Ferjani Asma
- Ferjani Sana
- Fidelia Hinson
- Fikry A.E.
- Fillo S.
- Fki-berrajah L.
- Fki-Berrajah Lamia
- Foda Iman
- Fokam Joseph
- Folarino O.
- Folorunsho Francine
- Foster-Nyarko Ebenezer
- Foudi Martin Maidadi
- Foulkes Benjamin H.
- Fournier Pierre-Edouard
- Fowora Muinah Adenike
- Fowotade Adeola
- Francisco Ngiambudulu M.
- Frans Ndahafa
- Fred Tei-Maya
- Freed Nikki
- Freeman Josh
- Freitas R. H.
- Frempong Hilda Opoku
- Fuh-Neba T.
- Fwoloshi Somda Soro Georgina
- Gaaloul I.
- Gad Ahmed F.
- Gadzama Galadima
- Gaies Emna
- Galal
- Galiwango Ronald M.
- Galvao Bruna
- Garcia Guillermo
- Gardoul Mouhcine
- Gargouri S.
- Gargouri Saba
- Garry R.
- Garus-Oas Nathalia
- Gaseitsiwe Simani
- Gatare Swaibu
- Gaye-Gaye Astou
- Gdoura Mariem
- Gedeon Jude
- Gelanew Tesfaye
- George Uwem E.
- Gerard Izuwayo
- GeurtsvanKessel Corine H.
- Gevao Sahr
- Gharmaz Hamza
- Ghassan Adib
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- Giandhari Jennifer
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- Girgis Samia Abdou
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- Githinji George
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- Goba Augustine
- Godwe Celestin
- Goedhals Dominique
- Goldstone R.
- Gomaa C.
- Gomaa Mokhtar
- Goodfellow Ian
- Goredema Alexander
- Gorman Richmond
- Gorova Vivianne
- Gosnell B. I.
- Gottberg A.
- Gouider Riadh
- Grace Chukwa
- Grad Alia
- Grant Donald S.
- Grantz Kyra
- Grayo Solène
- Greninger Alexander
- Guedouar Houssem
- Gueye Abdou Salam
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- Gueye Ousseynou
- Guindo Ibrahima
- Gumbo Hlanai
- Gumede Nicksy
- Guseva N. P.
- Gutema Gadissa
- Gutierrez Ana V.
- Gwayi S.
- Gyamfi Jones
- Gyapong John O.
- Hachid Aissam
- Hadad A.
- Haddad Sonia V.
- Hafez Hala
- Hafez M.M.
- Hailu Getnet
- Halafawy A.
- Halatoko Jacqueline Wemboo Afiwa
- Halilou Ibrahima
- Hamdani T.N.
- Hamdy M.S.
- Hammad M.
- Hammami A.
- Hammer David
- Hamza Ghamaz
- Hamzaoui Zaineb
- Handrick Susann
- Happi Anise N.
- Happi Christian
- Harding Doris
- Harvey R.
- Hassan Iman Abdillahi
- Hassan R.
- Hassan W.
- Hassany Mohamed
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- Heikel Jaafar
- Hellemans Jorn
- Helmy Sherine
- Hemlali Mouhssine
- Henson Sondes
- Heraud Jean-Michel
- Herring Belinda L.
- Hicham Charoute
- Hicham Elannaz
- Hihi Nardjes
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- Hilali Farida
- Holland LaRinda A.
- Hoornaert Laurien
- Hope Virginia
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- Howard Julia
- Hsiao Marvin
- Hsiao Nei-yuan
- Hsu Sharon
- Huang Meei-Li
- Huddleston John
- Hultquist Judd F.
- Hussein Salah Eldin
- Ian Lipkin W.
- Ibrahim Muntaser elTayeb
- Ibrahim Samira F.
- Ibrahim Tomade A.M.
- Ige F.A.
- Iguosadolo Nosamiefan
- Ihazmad Hassan
- Ihekweazu Chikwe
- Iknane A.A.
- Imam Zeinab S.
- Inglês L.
- Inndi Rui
- Intyre Leigh-Anne MC
- Iranzadeh Arash
- Ismael Nalia
- Ismail A.
- Ismail Arshad
- Isong Josiah Ayoola
- Issa Zoukaneirii
- Iwalokun Bamidele
- Iyanu Fred-Akintunwa
- Jain Komal
- Jalal D.
- Jalal Nourlil
- Jalloh Simbirie
- Jamal Fekkak
- Jambo Kondwani
- James Ayorinde Babatunde
- Jannoo N.
- Jefferies Sarah
- Jegede-Williams Anu
- Jelly Lauren
- Jerome Keith R
- Jimoh Yusuf
- Jiménez-Serrano Santiago
- Jo Wendy Karen
- JOEL Ireoluwa Yinka
- Johane Shirley
- Johnson Adeniji A.
- Johnson Bankole
- Joloba Moses
- Joseph Rageema
- Jouali Farah
- Jumaa A.B.
- Juru Agnes
- Kabamba Gabriel
- Kabanda Alice
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- Kaboré Firmin
- Kacem Imen
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- Kagnissode Sidonie A.M.
- Kagoné Thérèse
- Kakai Clement G.
- Kalantar K.
- Kaleebu Pontiano
- Kamal Mohamed
- Kamara Santigie
- Kamel Mina
- Kamga Rodrigue
- Kamoun S.
- Kamulegeya Rogers
- Kandaswamy Krishna Kumar
- Kandeil Ahmed
- Kandeil Ahmed
- Kane Mouhamed
- Kane Ndéye Coumba Touré
- Kanjau Lilian
- Kanjerwa Oscar
- Kanteh Abdoulie
- Kanyerezi Stephen
- Kapata Nathan
- Kapata P.C.
- Kapaya F.
- Kapin'a M.
- Karidioula Safiatou
- Karim Wasim Abdul
- Karray Hakim H.
- Karray Hela
- Kartti Souad
- Kasambara W.
- Kasmy Zohour
- Kassab Reham
- Kassim Samar Kamal
- Katabazi Ashaba Fred
- Katagirya Eric
- Kateete David Patrick
- Katyshev A.D.
- Kavunga-Membo Hugo
- Kay Gemma L.
- Kayali Ghazi
- Kayed Ahmed E
- Kayeyi N.
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- Kayuki Charles
- Kazeem Akano
- Kazorina E.V.
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- Keita S.
- Keita Sakoba
- Kemi Adedotun-Sulaiman
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- Kezakarayagwa Eric
- Khaireh Bouh Abdi
- Khalid Ennibi
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- Khamadi Samoel Ashimosi
- Khan Adam K.
- Kharat N.
- Khardine Fayez
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- Kharrat Maher
- Khumalo Z.
- Kibet Gilbert
- Kiconco Jocelyn
- Kidane Eleni
- Kiemdé Franklin
- Kifude Carol
- Kigozi Edgar
- Kiiza Ronald
- Kim L.
- Kimita Gathii
- Kimotho J.
- Kingsley Ojide C.
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- Kirimunda Samuel
- Kiritu Edward
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- Koivogui Joel
- Koka Hellen
- Kolomoets E.V.
- Kone Amadou
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- Konstantinus Iyaloo S.
- Koné Amariane
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- Kooepile Legodile
- Koopmans Marion
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- Kossi Komlan
- Kotey Erasmus
- Kouriba Bourema
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- Krasnov Y.M.
- Krasnov Ya.M.
- Kritsky A.A.
- Kujabi Mariama
- Kumordjie Selassie
- Kutkat Omnia
- Kutyrev V.V.
- Kwasah Lorreta
- Kwenda S.
- Kyei George B.
- Laamarti Meriem
- Laamrti Rokaia
- Laatiris Abdelkader
- Ladhari Hafsia
- Lagare Adamou
- Laguda-Akingba Oluwakemi
- Lahlou Amine Idriss
- Lahlou Idriss-Amine
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- Lalemi Mary
- Lambisia Arnold W.
- Lamboni Lallepak
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- Langat Sombo
- Laraqui Abdelilah
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- Latif Elwaleed M. Elamin Sara A.I
- Latifa Anga
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- Le-Viet Thanh
- Lee Justin
- Lee Kwok
- Leendertz Fabian
- Lefrançois Louise
- Lekana-Douki Bernard
- Lekana-Douki Sonia
- Lell Bertrand
- Lelo Eric A.
- Lemoine Frederick
- Lemtudo Alan
- Lesego Kuate-lere
- Lesetedi Onalethata
- Lessells Richard
- Lessler Justin
- Leta D.
- Leta Dereje
- Letaief A.
- Levasseur Anthony
- Leye Nafisatou
- Li Zhenghui
- Liberator Paul
- Liboro G.
- Licastro Danilo
- Lieu Vivi Hue-Trang
- Lim Efrem S.
- Lima Mendonça Maria da Luz
- Limbaso Samson Konongoi
- Lin L.
- Lin Michelle
- Lindsey Benjamiin B.
- Linh Le Thi Kieu
- Lipsi Maria Rosaria
- Lissauer Sam
- Lissom Abel
- Lista F.
- Livo Esemu
- Liwewe M.M.
- Liyai Rehema
- Lo Gora
- Lo Mamadou Beye Cheikh Ibrahima
- Lockman Shahin
- Lodiongo Dennis Kenyi
- Lojuan Abe
- Lokilo Emmanuel
- Long Kyle A.
- Lontchi Roméo Aimé Laclong
- Lorenzo-Redondo Ramy
- Loucoubar Cheikh
- Lule Daniel B.
- Lumembe Raphael
- Luo Hu
- Luquette Andrea E.
- Lusamaki Eddy K.
- Lutalo Tom
- Lutucuta Silvia
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- Luutu Moses
- M'cormack Violette V.
- Maaroufi Anderrahmane
- Maatoug Taha
- Mabika Diane A.
- Mabunda Nedio
- Mabunda Nédio
- MaCauley Jane
- Macheke Kutlo
- Mad W.
- Madeira Carla
- Madi W.Y.
- Madisa Tumisang
- Maeka Kenneth K.
- Maes Piet
- Magalhães Erica Luis Maria
- Magdeldin S.
- Magnussen Vanessa
- Maharaj Arisha
- Mahlakwane Kamela
- Mahlangu B.
- Mahmoud Galal
- Mahmoud Sara
- Mahrous N.
- Maida A.
- Maidane Yakob Gebregziabher
- Maiga Almoustapha I.
- Maiga Mamoudou
- Maiga Zimmerman
- Majanja Janet
- Makamure Beuty
- Makangara Jean-Claude C.
- Makhema Joseph
- Makiala-Mandanda Sheila
- Makki Yousif Rabih
- Makori T.
- Malabat Christophe
- Malagon François
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- Malolo I.
- Maloum Moustapha Nzamba
- Maluzi Kwitaka
- Maman Issaka
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- Mancon Alessandro
- Mandomando Inacio
- Manene Bulelani
- Manga Pasacaline
- Manickchund N.
- Manneh Jarra
- Manneh Paulina Joãozinho da Costa Jarra
- Manouana Gédéon Prince
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- Mansell Chris
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- Manuel Eusebio
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- Maphalala Gugu P.
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- Maqsood Rachel
- Marais Gert
- Marcello Alessandro
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- Margaglione Maurizio
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- Marie Claire Okomo Assoumou
- Marion Amujal
- Maritz Jean
- Marks Michael
- Marondera Blessing T.
- Marti-Carerras Joan
- Martin Darren P.
- Maruapula Dorcas
- Marx Jacques
- Marycelin Baba
- Masahiro K.
- Masakwe Clement
- Masete Godfrey
- Mashe Tapfumanei
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- Massinga Arsenia
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- Mathabo M.
- Mathieu Hota
- Mathur H.
- Matobo Mooko Marethabile
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- Maufrais Corinne
- Mavingui Patrick
- Mayaphi Sim
- Mayor Alfredo
- Maïté Soundélé
- Mba Nwando
- Mbala Placide K.
- Mbanne Maimouna
- Mbaye Aminata
- Mbegnan Coulibaly
- Mbembo Guy Paterne Malonga
- Mbhele Nokuzola
- Mbondoukwe Noé Patrick
- Mbongo-Nkama Elvyre
- Mboowa Gerald
- Mboup Aminata
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- Mbow Moustapha
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- McAuliffe Gary
- McInnis Bronwyn
- Mdini Imen
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- Melingui Sylvie
- Melloul Marouane
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- Mewono Ludovic
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- Mhuulu Lusia
- Micelli Loris
- Micheli Valeria
- Michuki George
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- Mills Margaret
- Mine Madisa
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- Mohamed Chenaoui
- Mohamed K.S.
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- Mohammed Hajjaji
- Mohammed K.S.
- Mohammed Khadija Said
- Mohammed Oumaima Ait Si
- Mohammed Youbi
- Mohktar Quaneeta
- Mohr Vanessa
- Moir Monika
- Mokhtar Gomaa
- Molenkamp Richard
- Momoh M.
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- Morton Ben
- Mosepele Mosepele
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- Motshosi Patience
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- Mouallif Mustapha
- Mouangala Davy Leger
- Mouhssine Hemlali
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- Moustafa Shimaa
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- Mphoyakgosi Thongbotho
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- Mulonga Kangwa
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- Mupeta F.
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- Mutai Beth
- Mutangana Dieudonne
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- Mutungi Joe
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- Mveang-Nzoghe Amandine
- Mvula Bernard
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- Mwenda Mulenga
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- Namulondo Joyce
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- Nari Ramon
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- Nasinghe Emmanuel
- Natasha Akwii Patience
- Nawfel Azami
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- Ndam N.T.
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- Ndaruhutse Jerome
- Ndeboko Bénédicte
- NDiaye Anna Julienne Selbe
- Ndiaye Birahim Piere
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- Ndiaye Ndack
- Ndiaye Yacine DIA Seni
- Ndiour Samba
- Ndjolo Alexis
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- Nene Vishvanath
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- Nkurunziza Jerome
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- Omuoyo Donwilliams O.
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- Ondo Georgelin Nguema
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- Osei-Wusu Israel
- Osiany Shebbar
- Osman Ikram Omar
- Oteng F.
- Otieno Edward
- Otuonye Ngozi Mirabel
- Ouadghiri Ouna
- Ouangole Garba
- Ouangraoua Soumeya
- Ouedraogo Abdoul-Salam
- Ouedraogo Léopold
- Ouedraogo Saïdou
- Ouffoué Kra
- Ouma Ahmed E. O.
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- Pisanelli Daniela
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- Preiser Wolfgang
- Prince-David Mireille
- Prosolek Sophie
- Puente Manoli Torres
- Quansah E.B.
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- Quedraogo Rabia
- Rachakonda Sivaramakrishna
- Rachid Benhida
- Rafai Clotaire Donatien
- Rafaï Clotaire D.
- Ragomzingba Frank E. Z.
- Raharinosy Vololoniaina
- Rahoui Jalila
- Raimond Petra
- Ramadan Dalia
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- Ramphal Upasana
- Ramphal Yajna
- Ramuth Magalutcheemee
- Ranaivoson Christian
- Ranaivoson Hafaliana C.
- Randriambolamanantsoa Tsiry
- Raouf A.
- Raoult Didier
- Rasmussen David A.
- Razafimanjato Helisoa
- Razanajatovo Norosoa H.
- Rebai Ahmed
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- Reynders Marijke
- Reynolds Steven J.
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- Rubin Sarah
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- Sanyang Bakary
- Sathees Saraswathi
- Sathyendran Vani
- Savaliya Nitin
- Sawa H.
- Sawadogo Yacouba
- Sayed Ahmed
- Sayed Salma
- Sbabou Laila
- Schaffner Stephen F.
- Scharnberg Jasmin
- Scheepers Cathrine
- Schindler Tobias
- Schlotterbeck Jasmin
- Schneider Julia
- Schubert Grit
- Seadawy M.G.
- Seadawy Mohamed
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- Sedjro Eclou
- Seffar Myriam
- Sekhsokh Yassmin
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- Semanda Patrick
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- Sene Pauline Yacine
- Serrano Laetitia
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- Wayengera Misaki
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- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
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