Petrov types of slowly rotating fluid balls

Circularly rotating axisymmetric perfect fluid space-times are investigated to second order in the small angular velocity. The conditions of various special Petrov types are solved in a comoving tetrad formalism. A number of theorems are stated on the possible Petrov types of various fluid models. It is shown that Petrov type II solutions must reduce to the de Sitter spacetime in the static limit. Two space-times with a physically satisfactory energy-momentum tensor are investigated in detail. For the rotating incompressible fluid, it is proven that the Petrov type cannot be D. The equation of the rotation function $\omega$ can be solved for the Tolman type IV fluid in terms of quadratures. It is also shown that the rotating version of the Tolman IV space-time cannot be Petrov type D.Comment: 14 pages, version to appear in Gen. Rel. Gra

Earth Radiation Budget Experiment (ERBE) scanner instrument anomaly investigation

The results of an ad-hoc committee investigation of in-Earth orbit operational anomalies noted on two identical Earth Radiation Budget Experiment (ERBE) Scanner instruments on two different spacecraft busses is presented. The anomalies are attributed to the bearings and the lubrication scheme for the bearings. A detailed discussion of the pertinent instrument operations, the approach of the investigation team and the current status of the instruments now in Earth orbit is included. The team considered operational changes for these instruments, rework possibilities for the one instrument which is waiting to be launched, and preferable lubrication considerations for specific space operational requirements similar to those for the ERBE scanner bearings

The hard to soft spectral transition in LMXBs - affected by recondensation of gas into an inner disk

Soft and hard spectral states of X-ray transient sources reflect two modes of accretion, accretion via a geometrically thin, optically thick disk or an advection-dominated accretion flow (ADAF). The luminosity at transition between these two states seems to vary from source to source, or even for the same source during different outbursts, as observed for GX 339-4. We investigate how the existence of an inner weak disk in the hard state affects the transition luminosity. We evaluate the structure of the corona above an outer truncated disk and the resulting disk evaporation rate for different irradiation. In some cases, recent observations of X-ray transients indicate the presence of an inner cool disk during the hard state. Such a disk can remain during quiescence after the last outburst as long as the luminosity does not drop to very low values (10^-4 to 10^-3 of the Eddington luminosity). Consequently, as part of the matter accretes via the inner disk, the hard irradiation is reduced. The hard irradiation is further reduced, occulted and partly reflected by the inner disk. This leads to a hard-soft transition at a lower luminosity if an inner disk exists below the ADAF. This seems to be supported by observations for GX 339-4.Comment: 9 pages, 4 figures, accepted for publication in Astronomy and Astrophysic

Endocrine Effects of Inhaled Corticosteroids in Children

Inhaled corticosteroids (ICSs) are widely used as first-line treatment for various chronic respiratory illnesses. Advances in devices and formulations have reduced their local adverse effects. However, as delivery of ICSs to the lungs improves, the systemic absorption increases, and an adverse effect profile similar to, although milder than, oral corticosteroids has emerged. The most serious potential adverse effect is adrenal insufficiency, which can be life threatening. Adrenal insufficiency occurs most in patients taking the highest doses of ICSs but is reported with moderate or even low doses as well. Our recommendations include greater vigilance in testing adrenal function than current standard practice. In patients with diabetes mellitus (types 1 and 2), an increase in glucose levels is likely, and diabetes medication adjustment may be needed when initiating or increasing ICSs. The risk of linear growth attenuation and adverse effects on bone mineral density is generally low but should be considered in the face of additional risk factors. On behalf of the Pediatric Endocrine Society Drugs and Therapeutics Committee, we present a review of the endocrine adverse effects of ICSs in children and offer recommendations relating to testing and referral. Limited data in particular realms diminish the strength of certain recommendations, and clinical judgment continues to be paramount

Flexible Session Management in a Distributed Environment

Many secure communication libraries used by distributed systems, such as SSL, TLS, and Kerberos, fail to make a clear distinction between the authentication, session, and communication layers. In this paper we introduce CEDAR, the secure communication library used by the Condor High Throughput Computing software, and present the advantages to a distributed computing system resulting from CEDAR's separation of these layers. Regardless of the authentication method used, CEDAR establishes a secure session key, which has the flexibility to be used for multiple capabilities. We demonstrate how a layered approach to security sessions can avoid round-trips and latency inherent in network authentication. The creation of a distinct session management layer allows for optimizations to improve scalability by way of delegating sessions to other components in the system. This session delegation creates a chain of trust that reduces the overhead of establishing secure connections and enables centralized enforcement of system-wide security policies. Additionally, secure channels based upon UDP datagrams are often overlooked by existing libraries; we show how CEDAR's structure accommodates this as well. As an example of the utility of this work, we show how the use of delegated security sessions and other techniques inherent in CEDAR's architecture enables US CMS to meet their scalability requirements in deploying Condor over large-scale, wide-area grid systems

Manipulation of Cold Atomic Collisions by Cavity QED Effects

We show how the dynamics of collisions between cold atoms can be manipulated by a modification of spontaneous emission times. This is achieved by placing the atomic sample in a resonant optical cavity. Spontaneous emission is enhanced by a combination of multiparticle entanglement together with a higher density of modes of the modified vacuum field, in a situation akin to superradiance. A specific situation is considered and we show that this effect can be experimentally observed as a large suppression in trap-loss rates.Comment: RevTex, 2 EPS figures; scheduled for Phys. Rev. Lett. 19 Feb 01, with minor change

Anatomy and Neurophysiology of the Taste System in Aged Animals a

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72005/1/j.1749-6632.1989.tb20989.x.pd

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation.

BackgroundMucopolysaccharidosis I (MPS IH) is a lysosomal storage disease treated with hematopoietic cell transplantation (HCT) because it stabilizes cognitive deterioration, but is insufficient to alleviate all somatic manifestations. Intravenous laronidase improves somatic burden in attenuated MPS I. It is unknown whether laronidase can improve somatic disease following HCT in MPS IH. The objective of this study was to evaluate the effects of laronidase on somatic outcomes of patients with MPS IH previously treated with HCT.MethodsThis 2-year open-label pilot study of laronidase included ten patients (age 5-13 years) who were at least 2 years post-HCT and donor engrafted. Outcomes were assessed semi-annually and compared to historic controls.ResultsThe two youngest participants had a statistically significant improvement in growth compared to controls. Development of persistent high-titer anti-drug antibodies (ADA) was associated with poorer 6-min walk test (6MWT) performance; when patients with high ADA titers were excluded, there was a significant improvement in the 6MWT in the remaining seven patients.ConclusionsLaronidase seemed to improve growth in participants <8 years old, and 6MWT performance in participants without ADA. Given the small number of patients treated in this pilot study, additional study is needed before definitive conclusions can be made

Gravitomagnetism and Relative Observer Clock Effects

The gravitomagnetic clock effect and the Sagnac effect for circularly rotating orbits in stationary axisymmetric spacetimes are studied from a relative observer point of view, clarifying their relationships and the roles played by special observer families. In particular Semer\'ak's recent characterization of extremely accelerated observers in terms of the two-clock clock effect is shown to be complemented by a similarly special property of the single-clock clock effect.Comment: 19 pages, LaTeX, IOP macros with package epsf and 1 eps figure, to appear in Classical and Quantum Gravity, slight revisio