First-Gen Students: Finding Their Purpose

The life of a first generation college student is one that is complex. Not only because of the fact they are the first in their family to embark on a college journey but because of the experiences they encounter. The various journeys they embark on throughout their time in college is what makes each student unique in their own right. And all of this is attributed to one thing, purpose. Without purpose, the journey of a college student is one without a destination. One that is just going through the motions. For our first generation college students, we want them to get the most out of their college experience so they can not only find their purpose but establish it. Purpose is the foundation of students as it is intertwined with their emotional, social and academic factors of their experience as a whole. Without purpose, the complex life of a college student is simply one without meaning

ALMA 1.3 Millimeter Map of the HD 95086 System

Planets and minor bodies such as asteroids, Kuiper-belt objects and comets are integral components of a planetary system. Interactions among them leave clues about the formation process of a planetary system. The signature of such interactions is most prominent through observations of its debris disk at millimeter wavelengths where emission is dominated by the population of large grains that stay close to their parent bodies. Here we present ALMA 1.3 mm observations of HD 95086, a young early-type star that hosts a directly imaged giant planet b and a massive debris disk with both asteroid- and Kuiper-belt analogs. The location of the Kuiper-belt analog is resolved for the first time. The system can be depicted as a broad ($\Delta R/R \sim$0.84), inclined (30\arcdeg$\pm$3\arcdeg) ring with millimeter emission peaked at 200$\pm$6 au from the star. The 1.3 mm disk emission is consistent with a broad disk with sharp boundaries from 106$\pm$6 to 320$\pm$20 au with a surface density distribution described by a power law with an index of --0.5$\pm$0.2. Our deep ALMA map also reveals a bright source located near the edge of the ring, whose brightness at 1.3 mm and potential spectral energy distribution are consistent with it being a luminous star-forming galaxy at high redshift. We set constraints on the orbital properties of planet b assuming co-planarity with the observed disk.Comment: accepted for publication in A

Inner edges of planetesimal belts: collisionally eroded or truncated?

The radial structure of debris discs can encode important information about their dynamical and collisional history. In this paper we present a 3-phase analytical model to analyse the collisional evolution of solids in debris discs, focusing on their joint radial and temporal dependence. Consistent with previous models, we find that as the largest planetesimals reach collisional equilibrium in the inner regions, the surface density of dust and solids becomes proportional to $\sim r^{2}$ within a certain critical radius. We present simple equations to estimate the critical radius and surface density of dust as a function of the maximum planetesimal size and initial surface density in solids (and vice versa). We apply this model to ALMA observations of 7 wide debris discs. We use both parametric and non-parametric modelling to test if their inner edges are shallow and consistent with collisional evolution. We find that 4 out of 7 have inner edges consistent with collisional evolution. Three of these would require small maximum planetesimal sizes below 10 km, with HR 8799's disc potentially lacking solids larger than a few centimeters. The remaining systems have inner edges that are much sharper, which requires maximum planetesimal sizes $\gtrsim10$ km. Their sharp inner edges suggest they could have been truncated by planets, which JWST could detect. In the context of our model, we find that the 7 discs require surface densities below a Minimum Mass Solar Nebula, avoiding the so-called disc mass problem. Finally, during the modelling of HD 107146 we discover that its wide gap is split into two narrower ones, which could be due to two low-mass planets formed within the disc.Comment: Accepted for publication in MNRAS, 21 pages, 11 figure

The importance of loose tobacco when considering capping pack size

Caps on tobacco pack sizes should include loose tobacco,as pack size varies more for loose tobacco than factory-made cigarettes. This may simplify purchase decisions for consumers and inventory management for retailers. Standardizing pack dimensions as well as the quantity of product within packs would further limit the potential of tobacco companies to use the packaging as a promotional tool

Busulfan and subsequent malignancy: An evidence-based risk assessment

BACKGROUND: The incidence of secondary malignancies associated with busulfan exposure is considered low, but has been poorly characterized. Because this alkylating agent is increasingly utilized as conditioning prior to gene therapy in nonmalignant hematologic and related disorders, more precise characterization of busulfan's potential contribution to subsequent malignant risk is warranted. PROCEDURE: We conducted a literature-based assessment of busulfan and subsequent late effects, with emphasis on secondary malignancies, identifying publications via PubMed searches, and selecting those reporting at least 3 years of follow-up. RESULTS: We identified eight pediatric and 13 adult publications describing long-term follow-up in 570 pediatric and 2076 adult hematopoietic cell transplant (HCT) recipients. Secondary malignancies were reported in 0.5% of pediatric HCT recipients, with no cases of myelodysplastic syndrome (MDS) or acute myelocytic leukemia (AML). Fatal secondary malignancies were reported in 0.8% of 1887 evaluable adult HCT recipients, and an overall incidence of secondary malignancies of 4.8% was reported in a subset of 389 evaluable adult patients. We also reviewed long-term results from eight publications evaluating lentiviral- and human promotor-based HSC-targeted gene therapy in 215 patients with nonmalignant conditions, in which busulfan/treosulfan monotherapy or busulfan/fludarabine was the only conditioning. Two malignancies were reported in patients with sickle cell disease (SCD), one of which was potentially busulfan-related. No additional malignancies were reported in 173 patients with follow-up of 5-12 years. CONCLUSION: The incidence of busulfan-related secondary malignancies is low, and likely to be substantially less than 1% in pediatric transplant recipients, especially those receiving busulfan monotherapy for nonmalignant conditions other than SCD

Are autistic traits measured equivalently in individuals with and without an Autism Spectrum Disorder?:An invariance analysis of the Autism Spectrum Quotient Short Form

It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent to which measures of autistic traits actually measure the same traits in the same way across those with and without an ASD. We addressed this question using a multi-group confirmatory factor invariance analysis of the Autism Quotient Short Form (AQ-S: Hoekstra et al. in J Autism Dev Disord 41(5):589-596, 2011) across those with (n = 148) and without (n = 168) ASD. Metric variance (equality of factor loadings), but not scalar invariance (equality of thresholds), held suggesting that the AQ-S measures the same latent traits in both groups, but with a bias in the manner in which trait levels are estimated. We, therefore, argue that the AQ-S can be used to investigate possible causes and consequences of autistic traits in both groups separately, but caution is due when combining or comparing levels of autistic traits across the two group

The REASONS Survey : resolved millimeter observations of a large debris disk around the nearby F Star HD 170773

Debris disks are extrasolar analogs to our own Kuiper Belt and they are detected around at least 17% of nearby Sun-like stars. The morphology and dynamics of a disk encode information about its history, as well as that of any exoplanets within the system. We used the Atacama Large Millimeter/submillimeter Array (ALMA) to obtain 1.3 mm observations of the debris disk around the nearby F5V star HD 170773. We image the face-on ring and determine its fundamental parameters by forward-modeling the interferometric visibilities through a Markov Chain Monte Carlo approach. Using a symmetric Gaussian surface density profile, we find a 71 ± 4 au wide belt with a radius of {193}-3+2 au, a relatively large radius compared with most other millimeter-resolved belts around late A/early F type stars. This makes HD 170773 part of a group of four disks around A and F stars with radii larger than expected from the recently reported planetesimal belt radius—stellar luminosity relation. Two of these systems are known to host directly imaged giant planets, which may point to a connection between large belts and the presence of long-period giant planets. We also set upper limits on the presence of CO and CN gas in the system, which imply that the exocomets that constitute this belt have CO and HCN ice mass fractions of <77% and <3%, respectively. This is consistent with solar system comets and other exocometary belts

Sensory Processing Sensitivity and its association with personality traits and affect: A meta-analysis

In two Bayesian meta-analyses, we investigated associations between Sensory Processing Sensitivity (SPS) and the Big Five personality traits (MA1) as well as both Positive and Negative Affect (MA2). Moderators were age and the three SPS subscales. In MA1 (8 papers, 6790 subjects), SPS in children correlated with Neuroticism (r\u202f=\u202f0.42) but did not with Extraversion, Openness, Agreeableness or Conscientiousness. In adults, SPS correlated with Openness (r\u202f=\u202f0.14) and Neuroticism (r\u202f=\u202f0.40) but did not with Extraversion, Agreeableness or Conscientiousness. In MA2 (19 papers, 5326 subjects), SPS in children correlated with Negative (r\u202f=\u202f0.29) and Positive Affect (r\u202f=\u202f0.21), but only with Negative Affect (r\u202f=\u202f0.34) in adults. Developmental and measurement aspects are discussed

A critical review of the evidence for nurses as information providers to cancer patients

To review evidence on the role of oncology nurses in the provision of information to cancer patients and to delineate evidence-based implications for clinical practice and research.Provision of information is central for the empowerment of patients to participate in their care. There is not enough evidence regarding the nursing role in the information delivery process in cancer patients.Descriptive literature review.From January 1990–2008, databases searched included Medline, CINAHL, PubMed, CancerLit and the Cochrane Library. Original research articles addressing the role of nurses in information delivery were included. We explored evidence on: (1) the effectiveness of nurses as information providers, (2) the way patients evaluate nurses’ input to information delivery, (3) the extent to which nurses contribute to information delivery to cancer patients and (4) the types of information provided by nurses.The most important findings were: (1) nurses’ role as information providers for cancer patients is prominent, especially after the initiation of treatment, (2) specialist nurses are very effective in providing information, (3) no clear evidence exists on how nurses compare with other health-care professionals as information providers and (4) some evidence exists that patients may prefer nurses as information providers at specific times in their treatment and especially in regards to symptom management.Well-designed studies provide some evidence that nurses are effective as information providers to cancer patients. Specifically, oncology nurses are able to provide information of both high quality and of appropriate quantity and to assist individuals to interpret information provided by others.Oncology nurses should be specifically educated and prepared to offer explicit, practical and timely information and they should be trained in interpersonal communication skills, which will increase their ability to comprehend patient information needs.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79127/1/j.1365-2702.2009.02954.x.pd