179 research outputs found
Validation of a Single-Nucleotide Polymorphism-Based Non-Invasive Prenatal Test in Twin Gestations : Determination of Zygosity, Individual Fetal Sex, and Fetal Aneuploidy
We analyzed maternal plasma cell-free DNA samples from twin pregnancies in a prospective blinded study to validate a single-nucleotide polymorphism (SNP)-based non-invasive prenatal test (NIPT) for zygosity, fetal sex, and aneuploidy. Zygosity was evaluated by looking for either one or two fetal genome complements, fetal sex was evaluated by evaluating Y-chromosome loci, and aneuploidy was assessed through SNP ratios. Zygosity was correctly predicted in 100% of cases (93/93; 95% confidence interval (CI) 96.1%-100%). Individual fetal sex for both twins was also called with 100% accuracy (102/102; 95% weighted CI 95.2%-100%). All cases with copy number truth were also correctly identified. The dizygotic aneuploidy sensitivity was 100% (10/10; 95% CI 69.2%-100%), and overall specificity was 100% (96/96; 95% weighted CI, 94.8%-100%). The mean fetal fraction (FF) of monozygotic twins (n = 43) was 13.0% (standard deviation (SD), 4.5%); for dizygotic twins (n = 79), the mean lower FF was 6.5% (SD, 3.1%) and the mean higher FF was 8.1% (SD, 3.5%). We conclude SNP-based NIPT for zygosity is of value when chorionicity is uncertain or anomalies are identified. Zygosity, fetal sex, and aneuploidy are complementary evaluations that can be carried out on the same specimen as early as 9 weeks' gestation
Measurements of the Mass and Full-Width of the Meson
In a sample of 58 million events collected with the BES II detector,
the process J/ is observed in five different decay
channels: , , (with ), (with
) and . From a combined fit of all five
channels, we determine the mass and full-width of to be
MeV/ and
MeV/.Comment: 9 pages, 2 figures and 4 table. Submitted to Phys. Lett.
A Measurement of Psi(2S) Resonance Parameters
Cross sections for e+e- to hadons, pi+pi- J/Psi, and mu+mu- have been
measured in the vicinity of the Psi(2S) resonance using the BESII detector
operated at the BEPC. The Psi(2S) total width; partial widths to hadrons,
pi+pi- J/Psi, muons; and corresponding branching fractions have been determined
to be Gamma(total)= (264+-27) keV; Gamma(hadron)= (258+-26) keV, Gamma(mu)=
(2.44+-0.21) keV, and Gamma(pi+pi- J/Psi)= (85+-8.7) keV; and Br(hadron)=
(97.79+-0.15)%, Br(pi+pi- J/Psi)= (32+-1.4)%, Br(mu)= (0.93+-0.08)%,
respectively.Comment: 8 pages, 6 figure
Partial Wave Analysis of
BES data on are presented. The
contribution peaks strongly near threshold. It is fitted with a
broad resonance with mass MeV, width MeV. A broad resonance peaking at 2020 MeV is also required
with width MeV. There is further evidence for a component
peaking at 2.55 GeV. The non- contribution is close to phase
space; it peaks at 2.6 GeV and is very different from .Comment: 15 pages, 6 figures, 1 table, Submitted to PL
Measurement of the Atmospheric Muon Spectrum from 20 to 3000 GeV
The absolute muon flux between 20 GeV and 3000 GeV is measured with the L3
magnetic muon spectrometer for zenith angles ranging from 0 degree to 58
degree. Due to the large exposure of about 150 m2 sr d, and the excellent
momentum resolution of the L3 muon chambers, a precision of 2.3 % at 150 GeV in
the vertical direction is achieved.
The ratio of positive to negative muons is studied between 20 GeV and 500
GeV, and the average vertical muon charge ratio is found to be 1.285 +- 0.003
(stat.) +- 0.019 (syst.).Comment: Total 32 pages, 9Figure
Measurement of Branching Ratios for Hadronic Decays
In a sample of 58 million events collected with the BES II detector,
the process J/ is observed in five decay channels: , , (with
), (with ) and . From
these signals, we determine ,
, ,
and .Comment: 8 pages, 1 figures and 4 table. Submitted to Phys. Lett.
Evidence of psi(3770) non-DD-bar Decay to J/psi pi+pi-
Evidence of decays to a non- final state is
observed. A total of \psi(3770) \to \PPJP events are
obtained from a data sample of 27.7 taken at center-of-mass
energies around 3.773 GeV using the BES-II detector at the BEPC. The branching
fraction is determined to be BF(\psi(3770) \to \PPJP)=(0.34\pm 0.14 \pm
0.09)%, corresponding to the partial width of \Gamma(\psi(3770) \to \PPJP) =
(80 \pm 33 \pm 23) keV.Comment: 8 pages, 7 figures, Submitted to Physics Letters
Search for K_S K_S in J/psi and psi(2S) decays
The CP violating processes J/psi-->K_S K_S and psi(2S)-->K_S K_S are searched
for using samples of 58 million J/psi and 14 million psi(2S) events collected
with the Beijing Spectrometer at the Beijing Electron Positron Collider. No
signal is observed, and upper limits on the decay branching ratios are
determined to be BR(J/psi-->K_S K_S) K_S K_S) <
4.6x10^{-6} at the 95% confidence level.Comment: 6 pages, 4 figures, submitted to Phys. Lett.
A Study of J/psi-->gamma gamma V(rho,phi) Decays with the BESII Detector
Using a sample of events collected with the BESII
detector, radiative decays , where or ,
are studied. A resonance around 1420 MeV/c (X(1424)) is observed in the
mass spectrum. Its mass and width are measured to be MeV/c and MeV/c,
respectively, and its branching ratio is determined to be . A
search for yields a 95% C.L. upper limit .Comment: 10 pages, 5 figures, submitted to PL
Measurements of J/psi --> p \bar{p}
The process J/\psi --> p \bar{p} is studied using 57.7 X 10^6 J/\psi events
collected with the BESII detector at the Beijing Electron Positron Collider.
The branching ratio is determined to be Br(J/\psi --> p \bar{p})=(2.26 +- 0.01
+- 0.14) X 10^{-3}, and the angular distribution is well described by
\frac{dN}{d cos\theta_p}=1+\alpha\cos^2\theta_p with \alpha = 0.676 +- 0.036 +-
0.042, where \theta_p is the angle between the proton and beam directions. The
value of \alpha obtained is in good agreement with the predictions of
first-order QCD.Comment: 6 pages, 2 figures, RevTex4, Submitted to Phys.Lett.
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