36 research outputs found

    Wave turbulence in the two-layer ocean model

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    This paper looks at the two-layer ocean model from a wave turbulence perspective. A symmetric form of the two-layer kinetic equation for Rossby waves is derived using canonical variables, allowing the turbulent cascade of energy between the barotropic and baroclinic modes to be studied. It turns out that energy is transferred via local triad interactions from the large-scale baroclinic modes to the baroclinic and barotropic modes at the Rossby deformation scale. From there it is then transferred to the large-scale barotropic modes via a nonlocal inverse transfer. Using scale separation a sys- tem of coupled equations were obtained for the small-scale baroclinic component and the large-scale barotropic component. Since the total energy of the small-scale component is not conserved, but the total barotropic plus baroclinic energy is conserved, the baroclinic energy loss at small scales will be compensated by the growth of the barotropic energy at large scales. It is found that this transfer is mostly anisotropic and mostly to the zonal component

    Steady states in Leith's model of turbulence

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    We present a comprehensive study and full classification of the stationary solutions in Leith's model of turbulence with a generalised viscosity. Three typical types of boundary value problems are considered: Problems 1 and 2 with a finite positive value of the spectrum at the left (right) and zero at the right (left) boundaries of a wave number range, and Problem 3 with finite positive values of the spectrum at both boundaries. Settings of these problems and analysis of existence of their solutions are based on a phase–space analysis of orbits of the underlying dynamical system. One of the two fixed points of the underlying dynamical system is found to correspond to a 'sharp front' where the energy flux and the spectrum vanish at the same wave number. The other fixed point corresponds to the only exact power-law solution—the so-called dissipative scaling solution. The roles of the Kolmogorov, dissipative and thermodynamic scaling, as well as of sharp front solutions, are discussed

    Structure and expression pattern of Oct4 gene are conserved in vole Microtus rossiaemeridionalis

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    <p>Abstract</p> <p>Background</p> <p>Oct4 is a POU-domain transcriptional factor which is essential for maintaining pluripotency in several mammalian species. The mouse, human, and bovine <it>Oct4 </it>orthologs display a high conservation of nucleotide sequence and genomic organization.</p> <p>Results</p> <p>Here we report an isolation of a common vole (<it>Microtus rossiaemeridionalis) Oct4 </it>ortholog. Organization and exon-intron structure of vole <it>Oct4 </it>gene are similar to the gene organization in other mammalian species. It consists of five exons and a regulatory region including the minimal promoter, proximal and distal enhancers. Promoter and regulatory regions of the vole <it>Oct4 </it>gene also display a high similarity to the corresponding regions of <it>Oct4 </it>in other mammalian species, and are active during the transient transfection within luciferase reporter constructs into mouse P19 embryonic carcinoma cells and TG-2a embryonic stem cells. The vole <it>Oct4 </it>gene expression is detectable starting from the morula stage and until day 17 of embryonic development.</p> <p>Conclusion</p> <p>Genomic organization of this gene and its intron-exon structure in vole are identical to those in all previously studied species: it comprises five exons and the regulatory region containing several conserved elements. The activity of the <it>Oct4 </it>gene in vole, as well as in mouse, is confined only to pluripotent cells.</p

    Symptomatic and silent cerebral ischemia (detected on MRI) in patients with type 2 diabetes mellitus after carotid revascularization procedures

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    Background: Type 2 diabetes mellitus (T2DM) is a significant independent risk factor for ischaemic stroke. Carotid revascularisation procedures are an effective method of primary and secondary stroke prevention. However, patients developed postoperative acute ischaemic lesions (AILs), which were identified via magnetic resonance imaging (MRI) of the brains. Most of the patients with these AILs lack clinically overt symptoms. Aims: To assess the risk of ischaemic brain damage in patients with T2DM in the setting of carotid angioplasty with stenting (CAS) or carotid endarterectomy (CAE). Materials and methods: This open prospective study comprised of 164 patients with carotid atherosclerosis, who have undergone either CAS or CAE. Patients with T2DM were included in Group 1: 38 patients and 28 patients with CAE. Group 2 included patients without T2DM: 62 patients with CAS and 36 patients with CAE. All patients underwent a thorough neurological examination and diffusion-weighted brain MRI. In patients with T2DM, plasma glucose levels and glycated haemoglobin (HbA1c) were determined and their relationships to brain damage were evaluated. Results: In CAS, there were no statistically significant differences in the AIL frequency in patients with and without T2DM. AILs were found in 15 patients with T2DM (39.8%) and 29 patients without T2DM (46.8%, р = 0.24); three patients without T2DM were diagnosed with stroke. Of the 28 patients with T2DM who underwent CAE, 13 had AIL (46.4%); three had stroke (10.7%). In patients without T2DM, AILs were less prevalent in seven cases (19.4%, р = 0.012) and appeared asymptomatic. Following CAS, the baseline HbA1c levels were higher in patients with T2DM who developed AILs compared to those who did not develop AIL, 7.8% &plusmn; 1.4% vs 7.1 &plusmn; 1.1% (р = 0.0469). Negative impact of hyperglycaemia on the risk of cerebral ischaemia was observed in patients who underwent CAE, the baseline fasting plasma glucose level was 8.5 &plusmn; 1.9 mmol/l vs 7.0 &plusmn; 1.5 mmol/l in patients without AIL (р = 0.014). The baseline HbA1c levels in patients with and without AILs were 8.0% &plusmn; 1.7% and 6.9% &plusmn; 0.9% respectively (р = 0.023). Conclusions: Carotid revascularisation procedure for patients with carotid atherosclerosis may be associated with risk of stroke and asymptomatic acute cerebral ischaemic lesions, which are more prevalent in patients with T2DM. Also, increased HbA1c levels is a risk factor for AIL

    Dynamics in nonlocal linear models in the Friedmann-Robertson-Walker metric

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    A general class of cosmological models driven by a nonlocal scalar field inspired by the string field theory is studied. Using the fact that the considering linear nonlocal model is equivalent to an infinite number of local models we have found an exact special solution of the nonlocal Friedmann equations. This solution describes a monotonically increasing Universe with the phantom dark energy.Comment: 18 pages, 3 figures, a few misprints in Section 5 have been correcte

    Analysis of scalar perturbations in cosmological models with a non-local scalar field

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    We develop the cosmological perturbations formalism in models with a single non-local scalar field originating from the string field theory description of the rolling tachyon dynamics. We construct the equation for the energy density perturbations of the non-local scalar field in the presence of the arbitrary potential and formulate the local system of equations for perturbations in the linearized model when both simple and double roots of the characteristic equation are present. We carry out the general analysis related to the curvature and entropy perturbations and consider the most specific example of perturbations when important quantities in the model become complex.Comment: LaTeX, 25 pages, 1 figure, v2: Subsection 3.2 and Section 5 added, references added, accepted for publication in Class. Quant. Grav. arXiv admin note: text overlap with arXiv:0903.517

    A chemical survey of exoplanets with ARIEL

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    Thousands of exoplanets have now been discovered with a huge range of masses, sizes and orbits: from rocky Earth-like planets to large gas giants grazing the surface of their host star. However, the essential nature of these exoplanets remains largely mysterious: there is no known, discernible pattern linking the presence, size, or orbital parameters of a planet to the nature of its parent star. We have little idea whether the chemistry of a planet is linked to its formation environment, or whether the type of host star drives the physics and chemistry of the planet’s birth, and evolution. ARIEL was conceived to observe a large number (~1000) of transiting planets for statistical understanding, including gas giants, Neptunes, super-Earths and Earth-size planets around a range of host star types using transit spectroscopy in the 1.25–7.8 μm spectral range and multiple narrow-band photometry in the optical. ARIEL will focus on warm and hot planets to take advantage of their well-mixed atmospheres which should show minimal condensation and sequestration of high-Z materials compared to their colder Solar System siblings. Said warm and hot atmospheres are expected to be more representative of the planetary bulk composition. Observations of these warm/hot exoplanets, and in particular of their elemental composition (especially C, O, N, S, Si), will allow the understanding of the early stages of planetary and atmospheric formation during the nebular phase and the following few million years. ARIEL will thus provide a representative picture of the chemical nature of the exoplanets and relate this directly to the type and chemical environment of the host star. ARIEL is designed as a dedicated survey mission for combined-light spectroscopy, capable of observing a large and well-defined planet sample within its 4-year mission lifetime. Transit, eclipse and phase-curve spectroscopy methods, whereby the signal from the star and planet are differentiated using knowledge of the planetary ephemerides, allow us to measure atmospheric signals from the planet at levels of 10–100 part per million (ppm) relative to the star and, given the bright nature of targets, also allows more sophisticated techniques, such as eclipse mapping, to give a deeper insight into the nature of the atmosphere. These types of observations require a stable payload and satellite platform with broad, instantaneous wavelength coverage to detect many molecular species, probe the thermal structure, identify clouds and monitor the stellar activity. The wavelength range proposed covers all the expected major atmospheric gases from e.g. H2O, CO2, CH4 NH3, HCN, H2S through to the more exotic metallic compounds, such as TiO, VO, and condensed species. Simulations of ARIEL performance in conducting exoplanet surveys have been performed – using conservative estimates of mission performance and a full model of all significant noise sources in the measurement – using a list of potential ARIEL targets that incorporates the latest available exoplanet statistics. The conclusion at the end of the Phase A study, is that ARIEL – in line with the stated mission objectives – will be able to observe about 1000 exoplanets depending on the details of the adopted survey strategy, thus confirming the feasibility of the main science objectives.Peer reviewedFinal Published versio

    Invariant solutions for the nonlinear diffusion model of turbulence

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    We study Leith's model of turbulence represented by a nonlinear degenerate diffusion equation (Leith 1967 Phys. Fluids 10 1409–16, Connaughton and Nazarenko 2004 Phys. Rev. Lett. 92 044501–506). The model is constructed such that in the case of vanishing viscosity, there are two steady-state solutions: the Kolmogorov spectrum that corresponds to the cascade state and a thermodynamic equilibrium distribution. Using group analysis, we have obtained integral equations which describe all essentially different invariant solutions of the Leith equation with or without viscosity. The integral equations defining these solutions reveal new possibilities for analytical and numerical studies. In these equations, the presence of arbitrary constants allows one to solve them for different boundary conditions. We have proved existence and uniqueness for such boundary value problems
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