2,327 research outputs found
Spacecraft Requirements Development and Tailoring
Spacecraft design is managed through the use of design requirements. Requirements are flowed from the highest level, the overall spacecraft, to systems, subsystems and ultimately individual components. Through the use of requirements, each part of the spacecraft will perform the functions that are required of it and will interface to the rest of the spacecraft. Functional requirements are used to make sure every component performs as expected and interface requirements ensure that each component works within the larger design environment where it operates. Writing good requirements is difficult and the verification of requirements can be expensive and time consuming. Because of this difficulty and expense, it is important that each requirement truly be required and critical to the overall performance of the vehicle. It is also important that requirements can be changed or eliminated as the system matures to minimize verification cost and schedule. The Capsule Parachute Assembly System (CPAS) Project is developing the parachute system for the NASA Multi-Purpose Crew Vehicle (MPCV) Orion Spacecraft. Throughout the development and qualification cycle for CPAS, requirements have been evaluated, added, eliminated, or more generically, tailored, to ensure that the system performs as required while minimizing the verification cost to the Program. One facet of this tailoring has been to delete requirements that do not add value to the overall spacecraft or are not needed. A second approach to minimize the cost of requirement verification has been to evaluate requirements based on the actual design as it has matured. As the design of the parachute system has become better understood, requirements that are not applicable have been eliminated. This paper will outline the evolution of CPAS requirements over time and will show how careful and considered changes to requirements can benefit the technical solution for the overall system design while allowing a Project to control costs
CPAS Airdrop Test Joint Recertification by Analysis
Airdrop testing of parachutes is a complicated endeavor that requires the custom design and certification of many critical components. The most direct path to certifying a component is to perform full scale testing with margin over the maximum loads expected to be seen in operation. However, other constraints often preclude the opportunity to perform full scale testing. In this paper, we present a case study where a problem arises in a joint that had been certified with a full scale test. There was no time or budget available to repeat the full scale testing after a redesign of the joint. Instead, we present a method of testing each failure mode at the component level to support a certification by analysis approach. The analysis itself was not complicated, but tradeoffs had to be made between different failure modes to arrive at the optimal design. The same approach was also applied back to the original joint to confirm that the failure mode that was not seen in full scale testing would have been caught by the proposed analysis. In the end, the new design was certified by analysis and worked without issue for the final six airdrop tests that used this joint
Membrane-Based Water Evaporator for a Space Suit
A membrane-based water evaporator has been developed that is intended to serve as a heat-rejection device for a space suit. This evaporator would replace the current sublimator that is sensitive to contamination of its feedwater. The design of the membrane-based evaporator takes advantage of recent advances in hydrophobic micropore membranes to provide robust heat rejection with much less sensitivity to contamination. The low contamination sensitivity allows use of the heat transport loop as feedwater, eliminating the need for the separate feedwater system used for the sublimator. A cross section of the evaporator is shown in the accompanying figure. The space-suit cooling loop water flows into a distribution plenum, through a narrow annulus lined on both sides with a hydrophobic membrane, into an exit plenum, and returns to the space suit. Two perforated metal tubes encase the membranes and provide structural strength. Evaporation at the membrane inner surface dissipates the waste heat from the space suit. The water vapor passes through the membrane, into a steam duct and is vented to the vacuum environment through a back-pressure valve. The back-pressure setting can be adjusted to regulate the heat-rejection rate and the water outlet temperature
Wrinkle initiation and development in heated webs on drums
Wrinkles often occur in webs heated on drums and rollers. Anecdotal evidence from vacuum metalizers suggests that wrinkles are initiated by small grit particles or surface imperfections that lift the web off the drum. An elliptical patch of web centered on the dirt particle is lifted off the drum against the tension pressure acting to restore contact. A numerical "tent model", based on plate theory, has been formulated to predict the critical transverse direction (TD) stress at which the web spontaneously lifts off the grit, forming the wrinkle. The model iterates to find the tent shape for a given TD stress, and then uses an interval halving method to determine the critical TD stress. Results from the model will be presented. It turns out that a simpler, analytical "draped beam" model gives similar dependence on parameters but over-predicts the value.Once a wrinkle initiates, it may grow to a size where it is more visible, but has limited length and is restrained against further growth. Further increase in compression enables it to grow by relieving the TD compressive stress in both the lifted-off region and the neighboring web still in contact with the drum. It will also extend in the machine direction (MD). In vacuum coating, wrinkling causes a loss in thermal contact with the cooled drum, the web heats up, expands and the wrinkle grows catastrophically
Stress in nurses : stress-related affect and its determinants examined over the nursing day
Peer reviewedPostprin
Deep Broadband Observations of the Distant Gamma-ray Blazar PKS 1424+240
We present deep VERITAS observations of the blazar PKS 1424+240, along with
contemporaneous Fermi Large Area Telescope, Swift X-ray Telescope and Swift UV
Optical Telescope data between 2009 February 19 and 2013 June 8. This blazar
resides at a redshift of , displaying a significantly attenuated
gamma-ray flux above 100 GeV due to photon absorption via pair-production with
the extragalactic background light. We present more than 100 hours of VERITAS
observations from three years, a multiwavelength light curve and the
contemporaneous spectral energy distributions. The source shows a higher flux
of (2.1) ph ms above 120 GeV in 2009 and
2011 as compared to the flux measured in 2013, corresponding to
(1.02) ph ms above 120 GeV. The measured
differential very high energy (VHE; GeV) spectral indices are
3.80.3, 4.30.6 and 4.50.2 in 2009, 2011 and 2013,
respectively. No significant spectral change across the observation epochs is
detected. We find no evidence for variability at gamma-ray opacities of greater
than , where it is postulated that any variability would be small and
occur on longer than year timescales if hadronic cosmic-ray interactions with
extragalactic photon fields provide a secondary VHE photon flux. The data
cannot rule out such variability due to low statistics.Comment: ApJL accepted March 17, 201
The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer
The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistance. This study aims to provide further evidence that MyD88 positive cancer cells are clinically significant, stem-like and reproducibly detectable for the purposes of prognostic stratification. Expression of TLR4 and MyD88 was assessed immunohistochemically in 198 paraffin-embedded ovarian tissues and in an embryonal carcinoma model of cancer stemness. In parallel, expression of TLR4 and MyD88 mRNA and regulatory microRNAs (miR-21 and miR-146a) was assessed, as well as in a series of chemosensitive and resistant cancer cells lines. Functional analysis of the pathway was assessed in chemoresistant SKOV-3 ovarian cancer cells. TLR4 and MyD88 expression can be reproducibly assessed via immunohistochemistry using a semi-quantitative scoring system. TLR4 expression was present in all ovarian epithelium (normal and neoplastic), whereas MyD88 was restricted to neoplastic cells, independent of tumour grade and associated with reduced progression-free and overall survival, in an immunohistological specific subset of serous carcinomas, p<0.05. MiR-21 and miR-146a expression was significantly increased in MyD88 negative cancers (p<0.05), indicating their participation in regulation. Significant alterations in MyD88 mRNA expression were observed between chemosensitive and chemoresistant cells and tissue. Knockdown of TLR4 in SKOV-3 ovarian cells recovered chemosensitivity. Knockdown of MyD88 alone did not. MyD88 expression was down-regulated in differentiated embryonal carcinoma (NTera2) cells, supporting the MyD88+ cancer stem cell hypothesis. Our findings demonstrate that expression of MyD88 is associated with significantly reduced patient survival and altered microRNA levels and suggest an intact/functioning TLR4/MyD88 pathway is required for acquisition of the chemoresistant phenotype. Ex vivo manipulation of ovarian cancer stem cell (CSC) differentiation can decrease MyD88 expression, providing a potentially valuable CSC model for ovarian cancer
Observation of two new baryon resonances
Two structures are observed close to the kinematic threshold in the mass spectrum in a sample of proton-proton collision data, corresponding
to an integrated luminosity of 3.0 fb recorded by the LHCb experiment.
In the quark model, two baryonic resonances with quark content are
expected in this mass region: the spin-parity and
states, denoted and .
Interpreting the structures as these resonances, we measure the mass
differences and the width of the heavier state to be
MeV,
MeV,
MeV, where the first and second
uncertainties are statistical and systematic, respectively. The width of the
lighter state is consistent with zero, and we place an upper limit of
MeV at 95% confidence level. Relative
production rates of these states are also reported.Comment: 17 pages, 2 figure
Observation of resonances consistent with pentaquark states in decays
Observations of exotic structures in the channel, that we refer to
as pentaquark-charmonium states, in decays are
presented. The data sample corresponds to an integrated luminosity of 3/fb
acquired with the LHCb detector from 7 and 8 TeV pp collisions. An amplitude
analysis is performed on the three-body final-state that reproduces the
two-body mass and angular distributions. To obtain a satisfactory fit of the
structures seen in the mass spectrum, it is necessary to include two
Breit-Wigner amplitudes that each describe a resonant state. The significance
of each of these resonances is more than 9 standard deviations. One has a mass
of MeV and a width of MeV, while the second
is narrower, with a mass of MeV and a width of MeV. The preferred assignments are of opposite parity, with one
state having spin 3/2 and the other 5/2.Comment: 48 pages, 18 figures including the supplementary material, v2 after
referee's comments, now 19 figure
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