Transnational Lives: Colonial Immigration Restrictions and the White Australia Policy in the Riverina District of New South Wales, 1860-1960

In Australia the historical debate on the effects of immigration restrictions on the Chinese people has focused largely on the White Australia Policy. By contrast, in this paper I focus on the relatively neglected topic of intercolonial migration and compare the impact of the colonial immigration restrictions of the 1880s and the White Australia Policy, using as an example the Riverina district of New South Wales. Many Chinese people were severely disadvantaged by the colonial immigration restrictions, particularly if they had strong commercial links on both sides of the NSW�Victorian border or needed special assistance from their compatriots. The local reaction in the Riverina to the tightening of anti-Chinese restrictions in 1888 in particular sits at odds with the popular impression of unrelenting animosity towards Chinese people in the pre-Federation period. Many white residents of the Riverina viewed the legislation with disdain and pleaded the case for change. Federation solved the problem of intercolonial migration, but it created many other difficulties for Chinese residents and this time the Riverina press was silent. With the same resilience and initiative of their forebears, however, many Chinese worked around these new impositions. Influence, money and friendship were, however, critical and those less well connected or affluent were at a much greater disadvantage. Intimidation from officials with its attendant risks of resentment and bitterness may have been of little concern in the colonial and post-colonial period, but today it should be, for the stakes are much higher

Evaluation of Immunomodulatory Biomarkers in a Pressure Overload Model of Heart Failure

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90380/1/phco.27.4.504.pd

Clindamycin Pharmacokinetics and Safety in Preterm and Term Infants

ABSTRACT Clindamycin may be active against methicillin-resistant Staphylococcus aureus , a common pathogen causing sepsis in infants, but optimal dosing in this population is unknown. We performed a multicenter, prospective pharmacokinetic (PK) and safety study of clindamycin in infants. We analyzed the data using a population PK analysis approach and included samples from two additional pediatric trials. Intravenous data were collected from 62 infants (135 plasma PK samples) with postnatal ages of 40 to 60 weeks PMA, 9 mg/kg) resulted in an unbound, steady-state concentration at half the dosing interval greater than a MIC for S. aureus of 0.12 μg/ml in >90% of infants. There were no adverse events related to clindamycin use. (This study has been registered at ClinicalTrials.gov under registration no. NCT01728363.

Safety profile of autologous macrophage therapy for liver cirrhosis

This work was supported by a Medical Research Council UK grant (Biomedical Catalyst Major Awards Committee; reference MR/M007588/1) to S.J. Forbes. We thank Z.M. Younossi (Center for Outcomes Research in Liver Diseases, Washington, DC, USA) for academic use of the CLDQ instrument and L.J. Fallowfield (Sussex Health Outcomes Research & Education in Cancer (SHORE-C), University of Sussex, UK) for advice about health-related quality of life assessment.Peer reviewedPostprintPostprintPostprintPostprin

The Arctic in the twenty-first century: changing biogeochemical linkages across a paraglacial landscape of Greenland

The Kangerlussuaq area of southwest Greenland encompasses diverse ecological, geomorphic, and climate gradients that function over a range of spatial and temporal scales. Ecosystems range from the microbial communities on the ice sheet and moisture-stressed terrestrial vegetation (and their associated herbivores) to freshwater and oligosaline lakes. These ecosystems are linked by a dynamic glacio-fluvial-aeolian geomorphic system that transports water, geological material, organic carbon and nutrients from the glacier surface to adjacent terrestrial and aquatic systems. This paraglacial system is now subject to substantial change because of rapid regional warming since 2000. Here, we describe changes in the eco- and geomorphic systems at a range of timescales and explore rapid future change in the links that integrate these systems. We highlight the importance of cross-system subsidies at the landscape scale and, importantly, how these might change in the near future as the Arctic is expected to continue to warm