The non-linearity between <ln A> and <Xmax> induced by the acceptance of fluorescence telescopes

The measurement of the average depth of the shower maximum is the most commonly used observable for the possible inference of the primary cosmic-ray mass composition. Currently, different experimental Collaborations process and present their data not in the same way, leading to problems in the comparability and interpretation of the results. Whereas is expected to be proportional to in ideal conditions, we demonstrate that the finite field-of-view of fluorescence telescopes plus the attenuation in the atmosphere can introduce a non-linearity into this relation, which is specific for each particular detector setup

The Pierre Auger Observatory: Results on Ultra-High Energy Cosmic Rays

The focus of this article is on recent results on ultra-high energy cosmic rays obtained with the Pierre Auger Observatory. The world's largest instrument of this type and its performance are described. The observations presented here include the energy spectrum, the primary particle composition, limits on the fluxes of photons and neutrinos and a discussion of the anisotropic distribution of the arrival directions of the most energetic particles. Finally, plans for the construction of a Northern Auger Observatory in Colorado, USA, are discussed.Comment: Proceedings of the International Workshop on Advances in Cosmic Ray Science, Waseda University, Shinjuku, Tokyo, Japan, March 2008; to be published in the Journal of the Physical Society of Japan (JPSJ) supplemen

The drugs don't sell: DIY heart health and the over-the-counter statin experience

This paper draws on a study of over-the-counter statins to provide a critical account of the figure of the ‘pharmaceutical consumer’ as a key actor in the pharmaceuticalisation literature. A low dose statin, promising to reduce cardiovascular risk, was reclassified to allow sale in pharmacies in the UK in 2004. We analysed professional and policy debates about the new product, promotional and sales information, and interviews with consumers and potential consumers conducted between 2008 and 2011, to consider the different consumer identities invoked by these diverse actors. While policymakers constructed an image of ‘the citizen-consumer’ who would take responsibility for heart health through exercising the choice to purchase a drug that was effectively rationed on the NHS and medical professionals raised concerns about ‘a flawed consumer’ who was likely to misuse the product, both these groups assumed that there would be a market for the drug. By contrast, those who bought the product or potentially fell within its target market might appear as ‘health consumers’, seeking out and paying for different food and lifestyle products and services, including those targeting high cholesterol. However, they were reluctant ‘pharmaceutical consumers’ who either preferred to take medication on the advice of a doctor, or sought to minimize medicine use. In comparison to previous studies, our analysis builds understanding of individual consumers in a market, rather than collective action for access to drugs (or, less commonly, compensation for adverse effects). Where some theories of pharmaceuticalisation have presented consumers as creating pressure for expanding markets, our data suggests that sociologists should be cautious about assuming there will be demand for new pharmaceutical products, especially those aimed at prevention or asymptomatic conditions, even in burgeoning health markets

Characterisation of the electromagnetic component in ultra-high energy inclined air showers

Inclined air showers - those arriving at ground with zenith angle with respect to the vertical theta > 60 deg - are characterised by the dominance of the muonic component at ground which is accompanied by an electromagnetic halo produced mainly by muon decay and muon interactions. By means of Monte Carlo simulations we give a full characterisation of the particle densities at ground in ultra-high energy inclined showers as a function of primary energy and mass composition, as well as for different hadronic models assumed in the simulations. We also investigate the effect of intrinsic shower-to-shower fluctuations in the particle densities.Comment: 31 pages, 18 figures, accepted for publication in Astroparticle Physic

Measurements of the Cosmic Ray Composition with Air Shower Experiments

In this paper we review air shower data related to the mass composition of cosmic rays above 10$^{15}$ eV. After explaining the basic relations between air shower observables and the primary mass and energy of cosmic rays, we present different approaches and results of composition studies with surface detectors. Furthermore, we discuss measurements of the longitudinal development of air showers from non-imaging Cherenkov detectors and fluorescence telescopes. The interpretation of these experimental results in terms of primary mass is highly susceptible to the theoretical uncertainties of hadronic interactions in air showers. We nevertheless attempt to calculate the logarithmic mass from the data using different hadronic interaction models and to study its energy dependence from 10$^{15}$ to 10$^{20}$ eV.Comment: 21 pages, invited review accepted for publication in Astroparticle Physics, Topical Issue on Cosmic Ray

A super massive black hole binary in 3C66B: future observational perspectives

Supermassive black hole binaries (SMBHBs) may exist in the centers of galaxies and active galactic nuclei (AGN) and are expected to be fairly common in the Universe as a consequence of merging processes between galaxies. The existence of SMBHBs can be probed by looking for double nuclei in galaxy centers or, more easily, detecting periodic behavior in the observed radio light curves. In a recent paper, Sudou et al. \cite{sudou2003} announced the first direct observation of an SMBHB. Using VLBI observations they found that the unresolved radio core of the radio galaxy 3C66B shows a well defined elliptical motion with a period of $1.05\pm 0.03$ yrs, implying the presence of a couple of massive black holes in the center of the galaxy. In the present paper we study the astrophysical implications of the existence of such an SMBHB in 3C66B. In particular we focus on the information that can be obtained from detecting a signal periodicity either in the $X$-ray and/or $\gamma$-ray light curves as a consequence of the motion of the black holes. These observations could be used to extract further information on the physical parameters of the SMBHB and partially solve the system parameter degeneracy. The detection of the gravitational wave spectrum emitted by such system may be used to completely determine the physical parameters of the binary system.Comment: 8 pages, 8 figures, in Press on Astronomy & Astrophysic

Status of Legislation and Regulatory Control of Public Health Pesticides in Countries Endemic with or at Risk of Major Vector-Borne Diseases

Background: Legislation and regulation of pesticides used in public health are essential for reducing risks to human health and the environment

Smooth-filamental transition of active tracer fields stirred by chaotic advection

The spatial distribution of interacting chemical fields is investigated in the non-diffusive limit. The evolution of fluid parcels is described by independent dynamical systems driven by chaotic advection. The distribution can be filamental or smooth depending on the relative strength of the dispersion due to chaotic advection and the stability of the chemical dynamics. We give the condition for the smooth-filamental transition and relate the H\"older exponent of the filamental structure to the Lyapunov exponents. Theoretical findings are illustrated by numerical experiments.Comment: 4 pages, 3 figure