114 research outputs found
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The stochastic modelling of kleptoparasitism using a Markov process
Kleptoparasitism, the stealing of food items from other animals, is a common behaviour observed across a huge variety of species, and has been subjected to significant modelling effort. Most such modelling has been deterministic, effectively assuming an infinite population, although recently some important stochastic models have been developed. In particular the model of Yates and Broom (Stochastic models of kleptoparasitism. J. Theor. Biol. 248 (2007), 480–489) introduced a stochastic version following the original model of Ruxton and Moody (The ideal free distribution with kleptoparasitism. J. Theor. Biol. 186 (1997), 449–458), and whilst they generated results of interest, they did not solve the model explicitly. In this paper, building on methods used already by van der Meer and Smallegange (A stochastic version of the Beddington-DeAngelis functional response: Modelling interference for a finite number of predators. J. Animal Ecol. 78 (2009) 134–142) we give an exact solution to the distribution of the population over the states for the Yates and Broom model and investigate the effects of some key biological parameters, especially for small populations where stochastic models can be expected to differ most from their deterministic equivalents
Who determines the ideal body? A Summary of Research Findings on Body Image
The globalization of media have paved way for Print and television advertisements to use images of thin female bodies to sell products and these advertisements are viewed by women all over the world. Through the media we are constantly bombarded with the western images of beautiful women and perfect bodies. Many surveys have proved the fact that men and women feel negative about their body image not only in the west but also in other parts of the world and the feminist scholars have tended that one should try to view the portrayal of idealized body image critically . In this connection, this paper, through a survey of relevant literature on body image, attempts to understand the following: 1) The concept of body image 2) Various determinants that idealize a woman’s body and define beauty standards 3) Influence of media on the body image of women 4) How the various determinants are interwoven targeting women, making them vulnerable to the idealized images. Keywords: Body image, Determinants, Medi
Field Performance and Diagnostic Accuracy of a Low-Cost Instrument-Free Point-of-Care CD4 Test (Visitect CD4) Performed by Different Health Worker Cadres among Pregnant Women
Measuring CD4 counts remains an important component of HIV care. The Visitect CD4 is the first instrument-free low-cost point-of-care CD4 test with results interpreted visually after 40 min, providing a result of 350 CD4 cells/mm3. The field performance and diagnostic accuracy of the test was assessed among HIVinfected pregnant women in South Africa. A nurse performed testing at the point-ofcare using both venous and finger-prick blood, and a counselor and laboratory staff tested venous blood in the clinic laboratory (four Visitect CD4 tests/participant). Performance was compared to the mean CD4 count from duplicate flow cytometry tests on venous blood (FACSCalibur Trucount). In 2017, 156 patients were enrolled, providing a total of 624 Visitect CD4 tests (468 venous and 156 finger-prick samples). Of 624 tests, 28 (4.5%) were inconclusive. Generalized linear mixed modeling showed better performance of the test on venous blood (sensitivity 81.7%; 95% confidence interval [CI] 72.3 to 91.1]; specificity 82.6%, 95% CI 77.1 to 88.1) than on finger-prick specimens (sensitivity 60.7%; 95% CI 45.0 to 76.3; specificity 89.5%, 95% CI 83.2 to 95.8; P 0.001). No difference in performance was detected by cadre of health worker (P 0.113) or between point-of-care versus laboratory-based testing (P 0.108). Adequate performance of Visitect CD4 with different operators and at the point of care, with no need of electricity or instrument, shows the potential utility of this device, especially for facilitating decentralization of CD4 testing services in rural areas
2001 Wild Blueberry CSREES Project Reports
The 2001 edition of the Wild Blueberry CSREES Progress Reports was prepared for the Maine Wild Blueberry Commission and the University of Maine Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Effect of Wild Blueberry Products on Oxidation in Meat Based Food Systems
2. Factors Affecting the Microbial and Pesticide Residues Levels on Wild Blueberries
3. Determination of Pesticide Residue Levels in Fresh and Processed Wild Blueberries
4. Separation of Maggot-Infested Wild Blueberries in the IQF Processing Line
5. Water Use of Wild Blueberries and the Impact of Plant Water Stress on Yields
6. Survey of Stem Blight and Leaf Spot Diseases in Wild Blueberry Fields
7. IPM Strategies
8. Control Tactics for Wild Blueberry Pest Insects, 2001
9. Biology and Ecology of Blueberry Pest Insects
10. Diurnal Bee Activity and Measurement of Honeybee Field Strength
11. Effect of Foliar-applied Iron (Fe) Chelate Concentration on Leaf Iron Concentration, Wild Blueberry Growth and Yield
12. Effect of Boron Application Methods on Boron Uptake in Wild Blueberries
13. Effect of Foliar Iron and Copper Application on Growth and Yield of Wild Blueberries
14. Effect of Fertilizer Timing on Wild Blueberry Growth and Productivity
15. Effect of Foliar Copper Application on Growth and Yield of Wild Blueberries
16. Effect of Prune-year Applications of Nutri-Phitetm P or Nutri-Phitetm P+K on Growth and Yield of Wild Blueberry (Vaccinium angustifolium Ait.)
17. Effect of Soil pH on Nutrient Uptake
18. Assessment of Azafenidin for Weed Control in Wild Blueberries
19. Assessment of Rimsulfuron for Weed Control in Wild Blueberries
20. Assessment of Pendimethalin for Weed Control in Wild Blueberries
21. Evaluation and Demonstration of Techniques for Filling in Bare Spots in Wild Blueberry Fields
22. Assessment of Sprout-less Weeder for Hardwood Control in Wild Blueberries
23. Wild Blueberry Extension Education Program in 2001
24. Evaluation of Fungicide Efficacy in Wild Blueberry Fields
25. 2001 Pesticide Groundwater Survey
26. Cultural Weed Management Using Sulfur to Lower the pH
27. Wild Blueberry Web Sit
Performance of a Novel Low-Cost, Instrument-Free Plasma Separation Device for HIV Viral Load Quantification and Determination of Treatment Failure in People Living with HIV in Malaysia: a Diagnostic Accuracy Study
HIV viral load (VL) testing is the recommended method for monitoring the response of people living with HIV and receiving antiretroviral therapy (ART). The availability of standard plasma VL testing in low- and middle-income countries (LMICs), and access to this testing, are limited by the need to use fresh plasma. Good specimen collection methods for HIV VL testing that are applicable to resource-constrained settings are needed. We assessed the diagnostic performance of the filtered dried plasma spot (FDPS), created using the newly developed, instrument-free VLPlasma device, in identifying treatment failure at a VL threshold of 1,000 copies/ml in fresh plasma. Performance was compared with that of the conventional dried blood spot (DBS). Venous blood samples from 201 people living with HIV and attending an infectious disease clinic in Malaysia were collected, and HIV VL was quantified using fresh plasma (the reference standard), FDPS, and DBS specimens. VL testing was done using the Roche Cobas AmpliPrep/Cobas TaqMan v2.0 assay. At a threshold of 1,000 copies/ml, the diagnostic performance of the FDPS was superior (sensitivity, 100% [95% confidence interval {CI}, 89.1 to 100%]; specificity, 100% [95% CI, 97.8 to 100%]) to that of the DBS (sensitivity, 100% [95% CI, 89.4 to 100%]; specificity, 36.8% [95% CI, 29.4 to 44.7%]) (P 0.001). A stronger correlation was observed between the FDPS VL and the plasma VL (r 0.94; P 0.001) than between the DBS VL and the plasma VL (r 0.85; P 0.001). The mean difference in VL measures between the FDPS and plasma (plasma VL minus FDPS VL) was 0.127 log10 copies/ml (standard deviation [SD], 0.32), in contrast to – 0.95 log10 copies/ml (SD, 0.84) between the DBS and plasma. HIV VL measurement using the FDPS outperformed that with the DBS in identifying treatment failure at a threshold of 1,000 copies/ml and compared well with the quantification of VL in plasma. The FDPS can be an attractive alternative to fresh plasma for improving access to HIV VL monitoring among people living with HIV on ART in LMICs
Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics
Background:
Lipids have critical functions in cellular energy storage, structure and signaling. Many individual lipid molecules have been associated with the evolution of prostate cancer; however, none of them has been approved to be used as a biomarker. The aim of this study is to identify lipid molecules from hundreds plasma apparent lipid species as biomarkers for diagnosis of prostate cancer.
Methodology/Principal Findings:
Using lipidomics, lipid profiling of 390 individual apparent lipid species was performed on 141 plasma samples from 105 patients with prostate cancer and 36 male controls. High throughput data generated from lipidomics were analyzed using bioinformatic and statistical methods. From 390 apparent lipid species, 35 species were demonstrated to have potential in differentiation of prostate cancer. Within the 35 species, 12 were identified as individual plasma lipid biomarkers for diagnosis of prostate cancer with a sensitivity above 80%, specificity above 50% and accuracy above 80%. Using top 15 of 35 potential biomarkers together increased predictive power dramatically in diagnosis of prostate cancer with a sensitivity of 93.6%, specificity of 90.1% and accuracy of 97.3%. Principal component analysis (PCA) and hierarchical clustering analysis (HCA) demonstrated that patient and control populations were visually separated by identified lipid biomarkers. RandomForest and 10-fold cross validation analyses demonstrated that the identified lipid biomarkers were able to predict unknown populations accurately, and this was not influenced by patient's age and race. Three out of 13 lipid classes, phosphatidylethanolamine (PE), ether-linked phosphatidylethanolamine (ePE) and ether-linked phosphatidylcholine (ePC) could be considered as biomarkers in diagnosis of prostate cancer.
Conclusions/Significance:
Using lipidomics and bioinformatic and statistical methods, we have identified a few out of hundreds plasma apparent lipid molecular species as biomarkers for diagnosis of prostate cancer with a high sensitivity, specificity and accuracy
2002 Wild Blueberry Project Reports
The 2002 edition of the Wild Blueberry Project Reports was prepared for the Wild Blueberry Commission of Maine and the Wild Blueberry Advisory Committee by researchers at the University of Maine, Orono. Projects in this report include:
1. Factors Affecting Microbial and Pesticide Residue Levels on Wild Blueberries
2. Effect of Blueberry Products on Oxidation in Meat Based Food
3. Determination of Pesticide Residue Levels in Freshly Harvested and Processed Wild Blueberries
4. Detection of Infested Wild Blueberries using Near-Infrared Spectroscopy
5. Investigation Of The Mechanism By Which Blueberry Fractions Maintain Arterial Integrity
6. Antioxidant Assessment in the Elderly
7. Water Use of Wild Blueberries and the Impact of Plant Water Stress on Yield
8. Control Tactics for Wild blueberry Pest Insects
9. IPM Strategies
10. Pest Biology
11. Wild Blueberry Pollination Research
12. Survey and Determination of Effective Control of Stem Blight and Leaf Spot Diseases in Wild Blueberry Fields
13. Effect of Foliar-applied Iron Chelate Concentration on Leaf Iron Concentration, Wild Blueberry Growth and Yield
14. Effect of Boron Application Methods on Boron Uptake in Wild Blueberries
15. Effect of Foliar N spray on Leaf N Concentration, Growth and Yield of Wild Blueberries
16. Effect of Foliar Spray (4-13-15) on Leaf Nutrient Concentration, Growth and Yield of Wild Blueberries
17. Effect of Foliar Copper Application on Growth and Yield of Wild Blueberries
18. Effect of Foliar Copper and/or Iron Application on Growth and Yield of Wild Blueberries
19. Effect of Soil pH on Nutrient Uptake
20. Assessment of Hexazinone Alternatives for Weed Control in Wild Blueberries and Weed Control
21. Evaluation of Fall Applications of Sulfonylurea Herbicides for Bunchberry Control in Wild Blueberries
22. Evaluation and Demonstration of Techniques for Filling in Bare Spots in Wild Blueberry Fields
23. Blueberry Extension Education Program Base
24. 2002 Pesticide Groundwater Survey
25. Cultural Weed Management using sulfur to lower the p
Accuracy of PECARN, CATCH, and CHALICE head injury decision rules in children: a prospective cohort study
© 2017 Elsevier Ltd Background Clinical decision rules can help to determine the need for CT imaging in children with head injuries. We aimed to validate three clinical decision rules (PECARN, CATCH, and CHALICE) in a large sample of children. Methods In this prospective observational study, we included children and adolescents (age
Australia\u27s health 1992 : the third biennial report of the Australian Institute of Health and Welfare
Australia\u27s Health is the most comprehensive and authoritative source of national information on health in Australia. Australia\u27s Health is published mid-year in even-numbered years and provides national statistics and related information that form a record of health status, service provision and expenditure in Australia
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