942 research outputs found

    Efetividade do treino pliométrico na performance de jogadores de basquetebol: revisão bibliográfica

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    Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em FisioterapiaObjetivo: Sumariar a evidência acerca dos efeitos do treino pliométrico na performance de jogadores de basquetebol. Metodologia: Pesquisa computadorizada nas bases de dados PubMed, PEDro e Web of Science de modo a selecionar estudos randomizados controlados que avaliassem o efeito de um programa de treino pliométrico em diferentes parâmetros de performance de atletas de basquetebol. Resultados: 8 estudos cumpriram os critérios de elegibilidade definidos, tendo apresentado os resultados para um total de 207 participantes e uma média de classificação metodológica de 5,6/10 na escala de PEDro. Os atletas sujeitos ao programa de treino pliométrico apresentaram melhorias significativas em diferentes parâmetros avaliados, capacidade de salto, equilíbrio, sprint, agilidade, força, capacidade de encestar e drible. Conclusão: Os estudos incluídos sugerem que o treino pliométrico associado a treino standard de basquetebol ou treino de fortalecimento é um método eficaz para melhorar a performance de atletas de basquetebol.Aim: To summarize the evidence about the effect of plyometric training on the basketball players’ performance. Methodology: Computerized research in PubMed, PEDro and Web of Science in order to select randomized controlled studies that assessed the effect of a plyometric training program in different performance parameters of basketball athletes. Results: 8 studies fulfilled the eligibility criteria, presenting the results for a total of 207 participants and an average of 5,6 of methodological classification in the PEDro Scale. Athletes submitted to a plyometric training program presented significant improvements in different parameters such as jumping capacity, balance, sprint, agility, strength, shooting and dribbling ability. Conclusion: Evidence suggests that plyometric training associated with either standard basketball or strengthening training is an effective method to improve basketball athletes’ performance.N/

    A Contribuição dos Museus para a Institucionalização e Difusão da Paleontologia.

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    Since the calls “cabinets of curiosities", the essence of natural history was consolidating itself with the birth of the museums and the development of the Museums of Natural History. This consolidation was reached through following activities: expeditions, field trips, collection classification works, catalogues of diffusion of scientific knowledge, educativ activities and expositions. The present paper intends to discuss the importance of the museal institutions for the studies of Paleontology; since the museums of Natural History had exerted a pioneering paper in the institutionalization of certain areas of knowledge, as Palaeontology, Anthropology and Experimental Physiology, in Brazil. The Paleontological studies in museums had collaborated in the specialization and modernization of the appearance of "new museum idea". As this new concept the museum is a space of diffusion of scientific knowledge, represented as an object that reflects the identity of the society without an obligator linking with physical constructions. However, the Brazilian museums have been sufficientlyobsolete, with problems that involve acquisition and maintenance of collections to production of temporary or permanent exhibitions. When the Brazilian institutions of natural history are analyzed they are not organized on the new museum conception and the digital age as the North American and European ones. Despite the difficulties found by the Museums since its birth as Institution in the 18th century, the contemporary development of Museology and Palaeontology as Science had contributed for the consolidation and institutionalization of both, helping the diffusion of scientific knowledge

    Skew deviation e ocular tilt reaction versus paralisia do nervo troclear

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    Skew deviation é o desalinhamento vertical dos olhos causado pordisfunção unilateral no tronco cerebral, cerebelo ou sistema vestibularperiférico, comprometendo as vias por onde transitam impulsosdos órgãos otolíticos aos núcleos oculomotores. Está frequentementeassociado a torção ocular e inclinação da cabeça, compondo, assim,a ocular tilt reaction. Neste artigo os autores ressaltam aspectoshistóricos, fisiológicos, etiopatogênicos e clínicos que contribuempara caracterizar ambas as condições, além da diferenciação clínicacom a paralisia do nervo troclear

    Comparison of daylighting simulation workflows and results using plugins for BIM and 3D Modeling programs: application on early phases of design process

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    The present paper investigated the application of the daylighting analysis features of the Insight BIM plugin, comparatively to DIVA, a plugin for a 3D Nurbs modeling software. Considering the early phases of the design process, workflows, simulation results and processing times were analyzed, focusing on the prediction of static (illuminance level) and dynamic (sDA300,50%) metrics. Simulations on both tools were performed in the context of analyzing the daylight behavior in a deep office room model, with and without light shelves. Results indicate that Insight has limitations compared to DIVA, especially concerning input data configuration flexibility. Simulation results presented significant similarity between Insight and DIVA in most cases, being the direct sun case the one in which illuminance levels differed the most. Insight presented longer processing time for the static metric and similar average time for the dynamic metric. Work findings indicate that Insight has important potential to contribute to daylighting analysis on early phases of design process, and points out to barriers to its adoption and correct use. Authors expect this paper to benefit architects, engineers and students on the comprehension of both tools

    O conhecimento de crianças de escola pública sobre alimentação saudável: relato de experiência

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    É sabido que a alimentação é fundamental para o desenvolvimento infantil, pois uma dieta saudável proporciona energia e nutrientes essenciais para o organismo. Além disso, a adoção de hábitos alimentares ajuda no desempenho acadêmico e cognitivo. Dessa maneira, a educação alimentar e nutricional é um tema importante e necessário para crianças, sendo especialmente abordado no âmbito escolar

    Marcas linguístico-discursivas de patriarcalismo em Helena, de Machado de Assis: um estudo dialógico

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    In a society influenced by economic conservatism, capitalization of goods and patriarchy, it is essential to resort to literature, more specifically from the 19th century, to verify which socio-historical aspects of that time remain visible in the chronotope of the works. Thus, in a critical way, it be- comes possible to identify the socially assigned roles in the novels and find out how those are expressed. The objective of this research is to analyze, dia- logically, which marks of patriarchy are present, in a reflected and refracted way, in the work Helena, by Machado de Assis. For this, we resorted to the theoretical-methodological assumptions of Bakhtin (2006 [1979]), Medve- dev (2016 [1928]) and Volóchinov (2017 [1929]), members of the Bakhtin Circle, as well as Chaves (1988), Fischer (2008) and Schwarz (2012). The results pointed to the fact that patriarchy is a constituent element of the nar- rative, which portrays arbitrarily imposed discourses, it was possible to ob- serve differences between the roles relegated to women and men.Em uma sociedade influenciada pelo conservadorismo econômico, pela capitalização dos bens e pelo patriarcalismo, torna-se imprescindível recorrer à literatura, mais especificamente do século XIX, para verificar que marcas constitutivas dessa época permanecem visíveis no cronotopo das obras. Assim, de forma crítica, torna-se possível identificar os papeis socialmente atribuídos nos romances e averiguar de que maneira aqueles se expressam. O objetivo desta pesquisa consiste em analisar, dialogicamente, que marcas de patriarcalismo se presentificam, de forma refletida e refratada, na obra Helena, de Machado de Assis. Para tanto, recorremos aos pressupostos teórico-metodológicos de Bakhtin (2006 [1979]), Medviédev (2016 [1928]) e Volóchinov (2017 [1929]), integrantes do Círculo de Bakhtin, bem como de Chaves (1988), Fischer (2008) e Schwarz (2012).  Os resultados apontaram para o fato de que o patriarcalismo é um elemento constituinte da narrativa, que retrata discursos arbitrariamente impostos, no constatar de diferenças entre as funções relegadas às mulheres e aos homens

    Comparisons of cardiorrespiratory responses in a hydrogymnastics exercise with and without horizontal movement on land and in aquatic environment

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    The aim of the study was to compare the cardiorespiratory responses during an hydrogymnastics exercise performed with and without horizontal movement on land environment (LE) and in a deep (DS) and in a shallow swimming pool (SS). Six YOUNG women performed the exercise during four minutes in each environment (LE, DS and SS) and situation (with and without horizontal movement) in a cadence of 80 bpm. The exercise consisted in a hip flexion/extension while the arms simulating a running movement. The heart rate (HR) and oxygen uptake (VO2 ) were veriefied during the last minute in each exercise and the rate of perceived exertion (RPE) was collected in the ending of the exercise. To variables comparisons was used ANOVA two-way for repeated measures with factors environment and situation (p < 0,05). For all cardiorespiratory variables analyzed, SS exercise were lower than that found on LE. Although, no difference was observed in the exercise performed on LE or in DS, except for the HR, that was lower during DS. Acording to the different situations, higher HR value was found during the exercise with horizontal movement when compared with the exercise without horizontal movement in the DS. These findings suggest the possibility to perform the exercise analyzed with similar energy expenditure and lower FC in DS when compared with exercise in LE. It is very important for people that need similar energy expenditure and lower cardiovascular overload during aquatic exercise.O objetivo do estudo foi comparar as respostas cardiorrespiratórias de um exercício de hidroginástica (corrida estacionária) realizado com e sem deslocamento horizontal no meio terrestre (MT), em piscina funda (PF) e em piscina rasa (PR). Seis mulheres jovens realizaram os exercícios durante 4 min numa cadência de 80 bpm. O exercício consistia em flexão e extensão de quadril com os braços simulando um movimento de corrida. A frequência cardíaca (FC) e o consumo de oxigênio (VO2 ) foram coletados no último minuto de exercício e a percepção de esforço (PE) foi coletada ao término do exercício. Para a comparação das variáveis utilizou-se ANOVA two-way para medidas repetidas com fatores meio e forma de execução (p < 0,05). Para todas as variáveis analisadas foram encontrados valores menores no exercício em PR comparado ao exercício no MT. Porém, nenhuma diferença foi observada entre o exercício no MT e em PF, exceto para a FC, que foi menor no exercício em PF. Em relação à forma de execução, para a FC, foram encontrados valores maiores no exercício com deslocamento quando comparado ao exercício sem deslocamento somente na PF. Estes achados sugerem a possibilidade de executar o exercício analisado em PF com gasto energético (GE) similar e FC menor quando comparado ao mesmo exercício no MT. Fato de grande relevância para populações que querem obter um GE semelhante ao exercício no MT, mas que necessitam de uma menor sobrecarga cardiovascular

    Alteração do filme lacrimal e superfície ocular em usuários crônicos de medicação antiglaucomatosa

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    PURPOSE: Tear film can be altered by chronic medications that may disrupt the equilibrium responsible for the functioning of the lacrimal gland and ocular surface. The purpose of this study was to determine if antiglaucomatous chronic treatment induced alterations in the tear film and ocular surface. METHODS: After informed consent, 21 patients using antiglaucomatous eye drops for more than 8 months and 20 age- and sex-matched volunteers without eye and systemic medications (control group) were enrolled. The data of ocular discomfort, fluorescein and lisamine green staining, tear film break-up time and Schirmer test were collected and compared by Student's t test. The impression cytology data were graded and compared by chi-square test. RESULTS: Patients chronically using antiglaucomatous medications presented with significant higher fluorescein staining (p=0.003), lisamine green staining (p=0.02) and lower TFBUT (p=0.001). The other comparedparameters, including impression cytology were similar between the treated and control group (p>0.05). CONCLUSIONS: The present study shows that the tear film and the ocular surface are altered in patients under antiglaucomatous medications. In common, all medications were preserved with benzalkonium chloride. Efforts to minimize the adverse effects of chronic use of antiglaucomatous drugs must be addressed.OBJETIVO: O filme lacrimal pode ser alterado por medicações crônicas, que podem comprometer o equilíbrio responsável pela função da glândula lacrimal e da superfície ocular. O objetivo desse estudo foi determinar se o tratamento crônico com drogas antiglaucomatosas induz alterações no filme lacrimal e superfície ocular. MÉTODOS: Após o consentimento informado, 21 pacientes usando drogas antiglaucomatosas por mais de 8 meses e 20 voluntários com similar distribuição etária e por sexo, não usuários de medicação ocular ou sistêmica (grupo controle) foram incluídos. Os dados do desconforto ocular, coloração com fluoresceína e lissamina verde, tempo de ruptura do filme lacrimal e teste de Schirmer foram colhidos e analisados pelo teste t de Student. A citologia de impressão foi avaliada e comparada pelo teste de qui-quadrado. RESULTADOS: Pacientes usando cronicamente medicação antiglaucomatosa apresentaram ignificativamente maior coloração por fluoresceína (p=0,003), lissamina verde (p=0,02) e menor TRFL (p=0,001). Os outros parâmetros comparados, incluindo a citologia de impressão foram similares entre o grupo tratado e controle (p>0,05). CONCLUSÕES: Esse estudo demonstra que o filme lacrimal e a superfície ocular estão alterados em usuários de medicação antiglaucomatosa. Essas medicações apresentam em comum o cloreto de benzalcônio como conservante. Esforços para minimizar efeitos adversos do uso crônico de drogas antiglaucomatosas devem ser considerados.CNPqFAEPAFAPES

    a clinical and molecular study

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    Funding This work was funded by Fundação para a Ciência e Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020) and the Associated Laboratory LS4FUTURE (LA/P/0087/ 2020), by Associação de Endocrinologia Oncológica (AEO), and by Instituto Português de Oncologia de Lisboa Francisco Gentil (IPOLFG). Carolina Pires was granted with a PhD scholarship by FCT - 2020.07120.BD. Ricardo Rodrigues was granted with a PhD scholarship by iNOVA4Health Research Unit - UIDP/04462/2020; UI/BD/ 154256/2022.OBJECTIVES: Anaplastic thyroid carcinoma (ATC) has a poor survival. The combination of Dabrafenib plus Trametinib (DT) had a significant impact in survival of BRAF p.V600E patients. However, durable responses may be compromised by resistance. We aim to present our experience with DT in BRAF positive ATC patients and compare the outcomes with usual therapy, and to study tumor molecular alterations in the DT group. METHODS: Patients treated between May 2018 and April 2022 in a tertiary referral center, assessed for BRAF status were included. Patients were divided in three groups: BRAF p.V600E treated with DT, BRAF wild type (WT) under multimodal therapy (MT), and BRAF WT under compassionate care (CC). Response was assessed monthly in the first 6 months and every 3 months afterwards, by RECIST 1.1. Overall survival (OS) and progression-free survival (PFS) were estimated with the Kaplan-Meier method and compared with the log-rank test. RESULTS: Twenty-seven ATC patients were included (DT = 9, MT = 8, and CC = 10). Median OS was 475 days for DT, 156 days for MT, and 39 days for CC (P < .001). At 12 months, only patients in the DT group were alive (71%). Median PFS was 270 days, in the DT group, compared with less than 32 days in BRAF WT (P < .001). No severe adverse events were reported. Molecular profiling showed that in one of the four clinical progressions, a pathogenic NRAS mutation was found. CONCLUSIONS: Our results show a significant real-world efficacy of Dabrafenib plus Trametinib in both survival and recurrence compared with standard treatment, with a good safety profile.publishersversionpublishe
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