Open Medical Library : cooperation and Scientific Communication Network through RSS

One of the fastest and most performing tools on Web 2.0 is RSS (Really Simple Syndication). It allows the access to digital content without constantly visiting the pages where it is stored. Syndication enables to share all kind of informationin XML format, and offers us the opportunity of showing our own content in other web pages in an integrated way, giving an added value to the information. In this communication we would like to present a Network Collaborative Project between medical libraries belonging to different institutions, located in different geographical areas and with different purposes, objectives and interests (some of them focusing on research and teaching and other on medical practice). Our medical libraries have incorporated "the content syndication", on the one hand, as another tool for medical librarian work and, on the other hand, as a value-added service in order to be useful to different users such as medical staff, teachers, researchers or students. RSS lets us share information channels, creating a space for collaborative research. Syndication is a great help to our users as it develops a new trend in the content management sector, which is changing considerably the relationship with information, for both users and librarians' point of view

Memoria de actividades del INTA Patagonia Norte 2018 - 2020

Con el objetivo de exponer las actividades y logros más destacados del Centro Regional Patagonia Norte, presentamos la memoria de actividades del ciclo 2018-2020 que recopila las investigaciones, trabajos de difusión en sus diversos formatos y actividades realizadas por las distintas unidades. Contempla el trabajo llevado adelante en las tres Estaciones Experimentales Agropecuarias: la EEA Bariloche, la EEA Alto Valle, la EEA Valle Inferior y el Área de Investigación y Desarrollo Tecnológico para la Agricultura Familiar (IPAF) y en las Agencias de Extensión Rural distribuidas en el territorio de las provincias de Río Negro y Neuquén. Este compilado pretende ser un resumen de los temas priorizados y orientados a la resolución de los problemas y demandas del territorio que es llevado adelante por nuestro personal profesional, técnico y de apoyo, con responsabilidad y compromiso hacia la sociedad. Asimismo, esta memoria incluye un abundante número de convenios celebrados que son el resultado del fortalecimiento de las políticas de vinculación y relacionamiento del Centro Regional. Destacamos el trabajo de todo el personal que en el año 2020 redobló sus esfuerzos por continuar con las actividades esenciales mediante la implementación de protocolos trabajo en la presencialidad y el uso de sistemas digitales de comunicación para asegurar la continuidad de las actividades a distancia. En este contexto fue necesario readaptar nuestras formas de comunicarnos y de relacionarnos para cumplir con los requerimientos institucionales y las demandas en el territorio. Agradecemos a las familias productoras, organizaciones, instituciones, gobiernos provinciales, municipales, Universidades, comunidad científica, profesionales y la comunidad en general que conforman el entramado territorial de la Norpatagonia.EEA Alto ValleFil: Castilla Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte; ArgentinaFil: Lacoste, Pablo Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte; ArgentinaFil: Lagorio, Paula. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte. Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Beretta, Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte. Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Perez, Sonia del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte. Estación Experimental Agropecuaria Valle Inferior del Río Negro; ArgentinaFil: Izaguirre, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte. Estación Experimental Agropecuaria Alto Valle; Argentin

Memoria de actividades del INTA Patagonia Norte 2021

Se presenta la memoria institucional del CR Patagonia Norte con los temas priorizados por las distintas unidades durante el 2021. Contiene enlaces directos a cada publicación para facilitar el acceso y consulta de los materiales. Con el objetivo de exponer las actividades y logros más destacados del Centro Regional Patagonia Norte, presentamos la memoria de actividades del 2021 que recopila las investigaciones, trabajos de difusión en sus diversos formatos y actividades realizadas por las distintas unidades. Contempla el trabajo llevado adelante en las tres Estaciones Experimentales Agropecuarias: la EEA Bariloche, la EEA Alto Valle, la EEA Valle Inferior y el Área de Investigación y Desarrollo Tecnológico para la Agricultura Familiar (IPAF) en Patagonia y en las Agencias de Extensión Rural distribuidas en el territorio de las provincias de Río Negro y Neuquén. Este compilado pretende ser un resumen de los temas priorizados y orientados a la resolución de los problemas y demandas del territorio que es llevado adelante por nuestro personal profesional, técnico y de apoyo, con responsabilidad y compromiso hacia la sociedad. Este documento digital contiene enlaces directos a cada publicación para facilitar el acceso y consulta de los materiales.EEA Alto ValleFil: Castilla Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte; ArgentinaFil: Lacoste, Pablo Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional Patagonia Norte; ArgentinaFil: Lagorio, Paula. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Beretta, Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bariloche; ArgentinaFil: Perez, Sonia del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Valle Inferior del Río Negro; ArgentinaFil: Izaguirre, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Alto Valle; Argentin

Open Medical Library: Cooperation and Scientific Communication Network through RSS

http://espace.library.uq.edu.au/view/UQ:179869One of the fastest and most performing tools on Web 2.0 is RSS (Really Simple Syndication). It allows the access to digital content without constantly visiting the pages where it is stored. Syndication enables to share all kind of information in XML format, and offers us the opportunity of showing our own content in other web pages in an integrated way, giving an added value to the information. In this communication we would like to present a Network Collaborative Project between medical libraries belonging to different institutions, located in different geographical areas and with different purposes, objectives and interests (some of them focusing on research and teaching and other on medical practice). Our medical libraries have incorporated “the content syndication”, on the one hand, as another tool for medical librarian work and, on the other hand, as a value-added service in order to be useful to different users such as medical staff, teachers, researchers or students. RSS lets us share information channels, creating a space for collaborative research. Syndication is a great help to our users as it develops a new trend in the content management sector, which is changing considerably the relationship with information, for both users and librarians’ point of view

Gasdermin B expression predicts poor clinical outcome in HER2-positive breast cancer

Altres ajuts: This work has been supported by the Community of Madrid (grant S2010/BMD-2303 to GMB), the Breast Cancer Research Foundation (BCRF) to JA. Alba Mota is a predoctoral student supported by a FPU fellowship (Spanish Ministry of Education, Culture and Sport). David Sarrio is a postdoctoral researcher funded by the AECC Scientific Foundation.Around, 30-40% of HER2-positive breast cancers do not show substantial clinical benefit from the targeted therapy and, thus, the mechanisms underlying resistance remain partially unknown. Interestingly, ERBB2 is frequently co-amplified and co-expressed with neighbour genes that may play a relevant role in this cancer subtype. Here, using an in silico analysis of data from 2,096 breast tumours, we reveal a significant correlation between Gasdermin B (GSDMB) gene (located 175 kilo bases distal from ERBB2) expression and the pathological and clinical parameters of poor prognosis in HER2-positive breast cancer. Next, the analysis of three independent cohorts (totalizing 286 tumours) showed that approximately 65% of the HER2-positive cases have GSDMB gene amplification and protein over-expression. Moreover, GSDMB expression was also linked to poor therapeutic responses in terms of lower relapse free survival and pathologic complete response as well as positive lymph node status and the development of distant metastasis under neoadjuvant and adjuvant treatment settings, respectively. Importantly, GSDMB expression promotes survival to trastuzumab in different HER2-positive breast carcinoma cells, and is associated with trastuzumab resistance phenotype in vivo in Patient Derived Xenografts. In summary, our data identifies the ERBB2 co-amplified and co-expressed gene GSDMB as a critical determinant of poor prognosis and therapeutic response in HER2-positive breast cancer

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Open medical library: cooperation and scientific communication

One of the fastest and most performing tools on Web 2.0 is RSS (Really Simple Syndication). It allows the access to digital content without constantly visiting the pages where it is stored. Syndication enables to share all kind of information in XML format, and offers us the opportunity of showing our own content in other web pages in an integrated way, giving an added value to the information. In this communication we would like to present a Network Collaborative Project between medical libraries belonging to different institutions, located in different geographical areas and with different purposes, objectives and interests (some of them focusing on research and teaching and other on medical practice). Our medical libraries have incorporated “the content syndication”, on the one hand, as another tool for medical librarian work and, on the other hand, as a value-added service in order to be useful to different users such as medical staff, teachers, researchers or students. RSS lets us share information channels, creating a space for collaborative research. Syndication is a great help to our users as it develops a new trend in the content management sector, which is changing considerably the relationship with information, for both users and librarians’ point of view

Open Medical Library : cooperation and Scientific Communication Network through RSS

One of the fastest and most performing tools on Web 2.0 is RSS (Really Simple Syndication). It allows the access to digital content without constantly visiting the pages where it is stored. Syndication enables to share all kind of informationin XML format, and offers us the opportunity of showing our own content in other web pages in an integrated way, giving an added value to the information. In this communication we would like to present a Network Collaborative Project between medical libraries belonging to different institutions, located in different geographical areas and with different purposes, objectives and interests (some of them focusing on research and teaching and other on medical practice). Our medical libraries have incorporated "the content syndication", on the one hand, as another tool for medical librarian work and, on the other hand, as a value-added service in order to be useful to different users such as medical staff, teachers, researchers or students. RSS lets us share information channels, creating a space for collaborative research. Syndication is a great help to our users as it develops a new trend in the content management sector, which is changing considerably the relationship with information, for both users and librarians' point of view

Smoking may increase the risk of hospitalization due to influenza

Background: Smoking may facilitate influenza virus infections and their severity. The objective was to investigate the risk of hospitalization due to influenza in Spanish smokers and ex-smokers. Methods: We carried out a multicentre, case-control study in 2011. Cases [patients a parts per thousand yen 18 years hospitalized > 24 h with real time polymerase chain reaction (RT-PCR)-confirmed influenza] were selected from 29 Spanish hospitals. For each case, we selected an outpatient aged a parts per thousand yen 18 years with RT-PCR-confirmed influenza matched by age (+/- 5 years), date of hospitalization of the case (+/- 10 days) and province of residence. We collected epidemiological variables, comorbidities and the smoking history. The risk of hospitalization due to smoking was determined by the adjusted odds ratio (aOR) using logistic regression. Results: We studied 471 hospitalized cases and 476 outpatient cases. Hospitalized cases had a higher frequency of influenza risk factors compared with outpatient cases. Hospitalized cases had a higher frequency of smoking (30.9% vs. 17.1%) and being ex-smokers (29.3% vs. 25.3%). Current smoking (aOR = 2.18, 95% CI: 1.23-3.87) and being an ex-smoker (aOR = 1.73, 95% CI: 1.07-2.82) were associated with the risk of hospitalization. Conclusions: Smoking may increase the risk of hospitalization in smokers and ex-smokers when infected by the influenza virus. Smoking prevention could reduce hospitalizations. Influenza vaccination is recommended for smokers