Global dynamics of microbial communities emerge from local interaction rules

Most microbes live in spatially structured communities (e.g., biofilms) in which they interact with their neighbors through the local exchange of diffusible molecules. To understand the functioning of these communities, it is essential to uncover how these local interactions shape community-level properties, such as the community composition, spatial arrangement, and growth rate. Here, we present a mathematical framework to derive community-level properties from the molecular mechanisms underlying the cell-cell interactions for systems consisting of two cell types. Our framework consists of two parts: a biophysical model to derive the local interaction rules (i.e. interaction range and strength) from the molecular parameters underlying the cell-cell interactions and a graph based model to derive the equilibrium properties of the community (i.e. composition, spatial arrangement, and growth rate) from these local interaction rules. Our framework shows that key molecular parameters underlying the cell-cell interactions (e.g., the uptake and leakage rates of molecules) determine community-level properties. We apply our model to mutualistic cross-feeding communities and show that spatial structure can be detrimental for these communities. Moreover, our model can qualitatively recapitulate the properties of an experimental microbial community. Our framework can be extended to a variety of systems of two interacting cell types, within and beyond the microbial world, and contributes to our understanding of how community-level properties emerge from microscopic interactions between cells

Disaster Management Education through Higher Education – Industry Collaboration in the Built Environment

Effectively responding to the current and dynamic construction labour market requirements is a major responsibility of higher education institutions (HEIs). HEIs aim to reduce the mismatch between what they deliver and what is required by the industry. Built environment professionals require continuous update of knowledge and education in order to effectively contribute to disaster management. However, the complex and multidisciplinary nature of disaster management education pose a challenge to the higher education institutions to make them more responsive to the industrial needs and to prepare the students for careers in disaster resilience. Adopting a lifelong learning approach would be appropriate for HEIs to maintain a through-life studentship and to provide disaster related knowledge and education on a continuous basis to respond to the labour market requirements. However, incorporating lifelong learning approach within the system of higher education is not easy and straightforward for HEIs. This is mainly because of the formal and bureaucratic nature of HEIs that acts as a barrier for providing effective lifelong learning education. In resolving this issue, HEIs are increasingly relying on the benefits associated with fostering close collaboration with external organisations such as industries, professional bodies and communities. In this context, this paper discusses the role of HEIs in providing disaster management education, the challenges associated with it, and the way of addressing the challenges through the higher education industry collaboration

Economic crisis and regional resilience: detecting the ‘geographical footprint’ of economic crisis in Greece

Taking stock from the research on regional resilience and by constructing a composite regional resilience indicator this paper sets out to detect the resistance/vulnerability of Greek regions and prefectures to economic crisis. Analysis is based on a newly elaborated dataset with socio-demographic, economic and welfare variables for Greek regions enabling to pre and after-crisis comparisons. Results highlight the multiplicity of ways in which crisis impacts on regions. Metropolitan areas and regions that are based on manufacturing activities seem to have been more vulnerable to crisis while places that are based on tourism such as islands are usually more resistant. Regional policy seems to be pro-cyclical to economic downturn

Marginally Better: My Husband’s Lover And Gay Portrayal

My Husband’s Lover is a Philippine telenovela that has garnered critical and commercial success (and along the way catapulting its two stars to A-list status), mainly due to a premise that heavily mirrors Ang Lee’s Brokeback Mountain (2005) but that which is unique to generally conservative Philippine society. Two high school best friends Eric Del Mundo (Dennis Trillo) and Vincent Soriano (Tom Rodriguez) also happen to be high school sweethearts, with the former leaving the latter.. Likewise, the latter’s family is the typical conservative Filipino family, so he decided to conceal his homosexuality for fear of being disowned. The two reunite years later, with Eric returning from the United States and learning that his former lover is engaged and is expecting a child with Lally Agatep (Carla Abellana). The series details the continuation of Vincent’s and Eric’s (still hidden) romance, and the former’s internal conflict, that between his true feelings and his morals. The dynamics of a love triangle peculiar to the average Filipino audience separate it from the typical Filipino romantic plotline, the portrayal of homosexuality being another Philippine TV trope that has been amply twisted so that it is “fresh.” Instead of the usual flamboyant gay best friend, the homosexuals are not only far from flamboyant, but are also the main characters of the series. Instead of being staples of beauty salons speaking in seeming code that is actually gay lingo, the homosexuals are affluent and well-spoken. The authors will buttress their textual analysis of all ten seasons of My Husband’s Lover with literature on the bakla and the global gay. With queer theory as the framework of the study, with emphasis on the theory’s element of performativity, the authors will also use several significant instances throughout the ten seasons of the series as premises to one of queer theory’s assumptions, that gender is fluid

Spectroscopy of formaldehyde in the 30140-30790cm^-1 range

Room-temperature absorption spectroscopy of formaldehyde has been performed in the 30140-30790cm^-1 range. Using tunable ultraviolet continuous-wave laser light, individual rotational lines are well resolved in the Doppler-broadened spectrum. Making use of genetic algorithms, the main features of the spectrum are reproduced. Spectral data is made available as Supporting Information

Homosexuality, health and humanity: Hlebotomy and biases Against gays

During the authors’ visit to hospital for a voluntary blood donation, one of them took notice of a problematic question in a survey that would determine whether one is fit to donate blood. This question was “Nakipagtalik ka na ba sa iyong kauri?” which, in English, translates to “Have you ever had sexual relations with your own kind?

Regional R&D efficiency in Korea from static and dynamic perspectives

Regional R&D efficiency in Korea from static and dynamic perspectives, Regional Studies. Research and development (R&D) efficiency has gained great attention in regional innovation research. This study examines the R&D efficiency patterns of 15 Korean regions for 2005–09. It employs data envelopment analysis to identify the regions' R&D performances relative to the best practices from the static perspective, and the Malmquist productivity index to evaluate their changes in performance within a given timeframe, providing a dynamic perspective. The results classify the Korean regions into deteriorating, lagging and improving groups, and indicate that most regions suffer from declining R&D productivity over time because of their inability to catch up with the best practices

Adult Cognitive and Non-cognitive Skills: An Overview of Existing PIAAC Data

As of summer 2019, more than 60 PIAAC datasets from participating countries worldwide were available for research purposes. These datasets can be differentiated, for example, in terms of their accessibility, the extent of the information provided, the population group in focus, and the design of the underlying study. PIAAC Public Use Files, for instance, are freely available and are therefore highly anonymised, whereas PIAAC Scientific Use Files are available only for scientific research purposes and provide access to more detailed variables. The majority of the PIAAC data are available as public use files, but some participating countries (e.g. Germany and the United States) have also made several scientific use files or other extended file versions available to the research community. Some of the available PIAAC datasets focus on specific population groups - for example, the incarcerated adult population in the United States. Regarding the design of the underlying studies, most available datasets are cross-sectional, but some longitudinal data already exist (e.g. PIAAC-L in Germany). The present chapter provides an overview of the structure, accessibility, and use of the PIAAC datasets available worldwide

Urban performance at different boundaries in England and Wales through the settlement scaling theory

The relationship between transport-led agglomeration and economic performance is evaluated in an English and Welsh context. We examine the effects of scale, i.e., inter- versus intra-city mobility infrastructure, on urban size–cost performance. An additional contribution of this paper lies in its use of power-law scaling models of urban systems, enabling an assessment of optimality in the trade-off between economic output and mobility costs accounting for ease of access within cities coupled with their built density. Findings suggest economic underperformance coincides with inadequate mobility at both inter- and intra-city scales, while overperformance is accompanied by overgrown urbanized area and escalating mobility costs

Motivations for innovation in the built environment: new directions for research

Innovation in the built environment involves multiple actors with diverse motivations. Policy-makers find it difficult to promote changes that require cooperation from these numerous and dispersed actors and to align their sometimes divergent interests. Established research traditions on the economics and management of innovation pay only limited attention to stakeholder choices, engagement and motivation. This paper reviews the insights that emerge as research in these traditions comes into contact with work on innovation from sociological and political perspectives. It contributes by highlighting growing areas of research on user involvement in complex innovation, collective action, distributed innovation and transition management. To differing extents, these provide approaches to incorporate the motivations of different actors into theoretical understanding. These indicate new directions for research that promise to enrich understanding of innovation