Unpacking Non-Dualistic Design: The Soma Design Case

We report on a somaesthetic design workshop and the subsequent analytical work aiming to demystify what is entailed in a non-dualistic design stance on embodied interaction and why a first-person engagement is crucial to its unfoldings. However, as we will uncover through a detailed account of our process, these first-person engagements are deeply entangled with second- and third-person perspectives, sometimes even overlapping. The analysis furthermore reveals some strategies for bridging the body-mind divide by attending to our inner universe and dissolving or traversing dichotomies between inside and outside; individual and social; body and technology. By detailing the creative process, we show how soma design becomes a process of designing with and through kinesthetic experience, in turn letting us confront several dualisms that run like fault lines through HCI's engagement with embodied interaction

A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer

Murine tissues harbor signature γδ T cell compartments with profound yet differential impacts on carcinogenesis. Conversely, human tissue-resident γδ cells are less well defined. In the present study, we show that human lung tissues harbor a resident Vδ1 γδ T cell population. Moreover, we demonstrate that Vδ1 T cells with resident memory and effector memory phenotypes were enriched in lung tumors compared with nontumor lung tissues. Intratumoral Vδ1 T cells possessed stem-like features and were skewed toward cytolysis and helper T cell type 1 function, akin to intratumoral natural killer and CD8+ T cells considered beneficial to the patient. Indeed, ongoing remission post-surgery was significantly associated with the numbers of CD45RA−CD27− effector memory Vδ1 T cells in tumors and, most strikingly, with the numbers of CD103+ tissue-resident Vδ1 T cells in nonmalignant lung tissues. Our findings offer basic insights into human body surface immunology that collectively support integrating Vδ1 T cell biology into immunotherapeutic strategies for nonsmall cell lung cancer

Prediction of performance and emission characteristics of diesel engine fuelled with waste biomass pyrolysis oil using response surface methodology

Advanced third generation biofuels like pyrolysis oil generated from waste biomass paves way for a cleaner and sustainable environment. An experimental-cum-statistical analysis was performed with the aim of determining the optimal engine operating conditions (with respect to compression ratio, load and fuel blend) to enhance the engine operating characteristics (performance and emission) of a diesel engine. Multiple regression models designed by using response surface methodology (RSM) for the output response variables like brake specific fuel consumption (BSFC), brake thermal efficiency (BTE), oxides of carbon (CO&CO2), hydrocarbon (HC), oxides of nitrogen (NOx) and smoke opacity were found to be statistically significant by analysis of variance. Optimization was carried out using desirability approach with a target of maximizing BTE and CO2 simultaneously by minimizing all other responses. From the results, it can be observed that the optimum conditions for bio-oil operation were 18:1 compression ratio, 20% fuel blend and 100% load. The models developed by RSM were validated through confirmatory experiments and found that the models were satisfactory to report the influence of compression ratio, load and bio-oil concentration on the operating characteristics of the diesel engine as the error in prediction is within 5%.Scopu

Nanopore Gradients on Porous Aluminum Oxide Generated by Nonuniform Anodization of Aluminum

A method for surface engineering of structural gradients with nanopore topography using the self-ordering process based on electrochemical anodization of aluminum is described. A distinct anodization condition with an asymmetrically distributed electric field at the electrolyte/aluminum interface is created by nonparallel arrangement between electrodes (tilted by 45°) in an electrochemical cell. The anodic aluminum oxide (AAO) porous surfaces with ordered nanopore structures with gradual and continuous change of pore diameters from 80 to 300 nm across an area of 0.5−1 cm were fabricated by this anodization using two common electrolytes, oxalic acid (0.3 M) and phosphoric acid (0.3 M). The formation of pore gradients of AAO is explained by asymmetric and gradual distribution of the current density and temperature variation generated on the surface of Al during the anodization process. Optical and wetting gradients of prepared pore structures were confirmed by reflective interferometric spectroscopy and contact angle measurements showing the ability of this method to generate porous surfaces with multifunctional gradients (structural, optical, wetting). The study of influence of pore structures on cell growth using the culture of neuroblastoma cells reveals biological relevance of nanopore gradients and the potential to be applied as the platform for spatially controllable cell growth and cell differentiation.Krishna Kant, Suet P. Low, Asif Marshal, Joseph G. Shapter, and Dusan Losi

Le déclin et la chute de Napoléon (3e édition) / par le maréchal vicomte Wolseley

Contient une table des matièresAvec mode text

Nanopore gradients on porous aluminum oxide generated by nonuniform anodization of aluminum

A method for surface engineering of structural gradients with nanopore topography using the self-ordering process based on electrochemical anodization of aluminum is described. A distinct anodization condition with an asymmetrically distributed electric field at the electrolyte/aluminum interface is created by nonparallel arrangement between electrodes (tilted by 45°) in an electrochemical cell. The anodic aluminum oxide (AAO) porous surfaces with ordered nanopore structures with gradual and continuous change of pore diameters from 80 to 300 nm across an area of 0.5-1 cm were fabricated by this anodization using two common electrolytes, oxalic acid (0.3 M) and phosphoric acid (0.3 M). The formation of pore gradients of AAO is explained by asymmetric and gradual distribution of the current density and temperature variation generated on the surface of Al during the anodization process. Optical and wetting gradients of prepared pore structures were confirmed by reflective interferometric spectroscopy and contact angle measurements showing the ability of this method to generate porous surfaces with multifunctional gradients (structural, optical, wetting). The study of influence of pore structures on cell growth using the culture of neuroblastoma cells reveals biological relevance of nanopore gradients and the potential to be applied as the platform for spatially controllable cell growth and cell differentiation.

In my sweet little Alice blue gown, when I first wandered [first line of chorus]

Performers: Roland Young, Alan Marshal, May Robson, Billie Burke, Stuart Robertson, Arthur TreacherPiano, Voice and Chord