Improvement and sustainable management of river corridors in the Iberian Atlantic Region

Resumen de la contribución presentada en el congreso.SER Europe Conference, Restoration in the Era of Climate Change (11th, 2018, Reykjavick)Se incluyen 2 archivos: resumen de la ponencia y póster de la misma.VERBATIM: In the Iberian Atlantic Region, there are several landscape change processes (changes in the land use, presence of invasive species, activities regarding public use, intensification of agricultural and livestock farming, climate change) and phytosanitary problems (alder diseases caused by Phytophthora ssp.) that, currently, are threat factors of river corridor habitats. These factors are deteriorating and fragmenting them, and having a relevant impact on their functionality. The LIFE Fluvial project aims to mitigate these consequences, to improve the conservation status and to develop sustainable management measures of river and fluvio-estuarine corridors. Selected areas in the project are Natura 2000 sites belonging to several river basins located in the northwest of the Iberian Peninsula (Spain and Portugal). To this aim, LIFE Fluvial has designed the following actions: A detailed analysis of the current status and implementation of a trans-national model for the sustainable management of river corridors to reduce the negative impact caused by the threats and to avoid their spread towards other UE territories. Design and implementation of restoration projects to improve conservation status of the natural habitats of interest, connectivity and to reduce fragmentation. Control of invasive flora species that pose a threat to the conservation of river corridors, and improvement of their phytosanitary state by removing trees infected by Phytophthora Dissemination of the environmental relevance of river corridors and social awareness in terms of socioeconomic benefits and ecosystem services provided. Improvement of training/education and technical empowerment of the stakeholders involved in the management and conservation of river corridors. The project lasts four years (2017-2021) and includes a system to monitor the impact of the actions on habitats and ecosystem services provided by river corridors

Nanoparticle penetration and transport in living pumpkin plants: in situ subcellular identification

<p>Abstract</p> <p>Background</p> <p>In recent years, the application of nanotechnology in several fields of bioscience and biomedicine has been studied. The use of nanoparticles for the targeted delivery of substances has been given special attention and is of particular interest in the treatment of plant diseases. In this work both the penetration and the movement of iron-carbon nanoparticles in plant cells have been analyzed in living plants of <it>Cucurbita pepo</it>.</p> <p>Results</p> <p>The nanoparticles were applied <it>in planta </it>using two different application methods, injection and spraying, and magnets were used to retain the particles in movement in specific areas of the plant. The main experimental approach, using correlative light and electron microscopy provided evidence of intracellular localization of nanoparticles and their displacement from the application point. Long range movement of the particles through the plant body was also detected, particles having been found near the magnets used to immobilize and concentrate them. Furthermore, cell response to the nanoparticle presence was detected.</p> <p>Conclusion</p> <p>Nanoparticles were capable of penetrating living plant tissues and migrating to different regions of the plant, although movements over short distances seemed to be favoured. These findings show that the use of carbon coated magnetic particles for directed delivery of substances into plant cells is a feasible application.</p

Stability of temocillin in outpatient parenteral antimicrobial therapy: is it a real option?

[Background] Temocillin is an interesting alternative to carbapenems for susceptible Enterobacteriaceae. Although its use in outpatient parenteral antimicrobial therapy (OPAT) programmes has generated interest, this has been hampered by the lack of stability data.[Objectives] The purpose of the present study was to evaluate the physical and chemical stability of temocillin at the recommended dose for its use in OPAT programmes, contained in polypropylene infusion bags or polyisoprene elastomeric devices at different temperatures, and to describe a novel LC-MS/MS developed for the quantification of temocillin.[Methods] Temocillin daily dose (6 g) was diluted in 500 mL of 0.9% sodium chloride to obtain a final concentration of 12 g/L. This solution was stored at 4°C, 25°C, 32°C and 37°C for 72 h, both in polypropylene infusion bags and in polyisoprene elastomeric pumps. Physical and chemical stability were evaluated during 72 h after manufacturing. Solutions were considered stable if colour, clearness and pH remained unchanged and if the percentage of intact drug was ≥90%.[Results] Temocillin attained the chemical stability criterion of ≥90% of the original concentration for the whole experiment in both devices at 4°C, 25°C and 32°C. At 37°C, temocillin was stable for 24 h but its concentration dropped below 90% from that timepoint. No precipitation occurred and minor colour changes were observed.[Conclusions] Temocillin is stable under OPAT conditions and it would be an appropriate candidate for the treatment of patients who can be discharged to complete therapy in an OPAT programme. For this study, an LC-MS/MS method was developed.This work was supported by the Sociedad Española de Farmacia Hospitalaria and the AFinf Working Group for the project ‘Stability study of antimicrobials under conditions analogous to the outpatient parenteral antibiotic therapy program (OPAT)’. A.G.-V. and L.H.-H. were supported by the Instituto de Salud Carlos III, co-financed by the European Development Regional Fund (‘A way to 251 achieve Europe’). A.G.-V. received financial support from the Subprograma Miguel Servet (CP19/00159). L.H.-H. received financial support from the Subprograma Juan Rodés (JR22/00049).Peer reviewe

Desarrollo de una presentación interactiva y multimedia orientada a la docencia del análisis cinemático del Movimiento Armónico Simple

Nowadays, computers suppose a great potential as complementary didactic tool to traditional means of education. For that reason, the advantage of this potential is considered by the work group, creating interactive and multimedia presentations oriented to facilitate teaching of different physics fields. In particular, the objective of this work is the design of a presentation oriented to teaching kinematical aspects of the simple harmonic movement. Given the dynamic nature of the subject, it is evident the adventages that suppose an animated presentation which it helps the student to understand the kinematical magnitudes. This tool will be very useful to the professor as complement of theoretical classes, and available to the students in the reinforcement of the knowledge.Es evidente el gran potencial que el ordenador supone como herramienta didáctica complementaria a los medios de enseñanza tradicionales. Es por ello que el grupo de trabajo se plantea el aprovechamiento de este potencial, creando presentaciones interactivas y multimedia orientadas a la docencia en los distintos campos de la física.En concreto, en este trabajo se plantea el diseño de una presentación orientada a la docencia de los aspectos cinemáticas del movimiento armónico simple. Dada la naturaleza dinámica del tema en cuestión, es evidente las ventajas que supone disponer de una presentación animada del mismo que ayude al alumno a entender la magnitudes cinemáticas implicadas, herramientas de gran utilidad para el profesor como complemento de sus clases teóricas, y disponible para alumnos de ayuda en el afianzamiento de los conocimientos

Vocational education student’s and teacher’s perceptions about responsibility through adventure program and responsibility Hellison’s mode

El desarrollo de competencias personales y socialesen el alumnado del ciclo formativo de Conducción de Actividades Físico-Deportivas en el Medio Natu-ral (CAFD), es un objetivo del currículo que es nece-sario promover de forma sistemática. En el presenteestudio, se ha implementado un programabasado en el modelo de responsabilidad personal y social de Hellison (2011), junto con la pedagogía de la aven-tura (Parra, Caballero y Domínguez, 2009), para promover el desarrollo de la responsabilidad (defi-nida según el programa en 5 niveles de responsabi-lidad, asociada a diferentes habilidades personales y sociales) a través de las actividades físicas en elmedio natural. El objetivo de la investigación fue conocer la percepción del alumnado y del profeso-rado de CAFD, sobre el desarrollo de la responsabili-dad. El programa se implementó durante 5 meses, 15 horas a la semana, por tres profesores, en tres módulos profesionales diferentes. El instrumento empleado fue el cuestionario de evaluación del aprendizaje del alumno (ad hoc), en la versión del alumnado y en la del profesorado, que se empleó aplicó tras la intervención (Caballero, 2012; Caballe-ro-Blanco y Delgado-Noguera, 2014). Los resultados obtenidos muestran que tanto el alumnado como el profesorado han percibido una evolución positiva encuanto al desarrollo de la responsabilidad (asociada a los 5 niveles de responsabilidad). Por tanto, es posible concluir que el programa ha generado una percepción positiva sobre el desarrollo de la respon-sabilidad en alumnos del ciclo formativo de CAFD.To develop students’s personal and social skills about the vocational education qualifications on outdoor activities (CAFD) is the principal aim of the curricular programme. In this study, we were im-plemented a program based on personal and social responsibility Hellison’ model (2011), complementedwith an adventure pedagogy (Parra, Caballero y Domínguez, 2009), to promote the responsibility (defined in 5 responsibility levels), associate to dif-ferences personal and social skills). The purpose of this study was to assess the vocational education outdoor activities student’s and teacher’s CAFD perceptions about to responsibility development. The program was implemented a long five months, which meant 15 hours per week, by three teachers in three different professional modules. The instru-ment used was the questionnaire to assess the learning perceptions (ad hoc), by student’s versionand teacher’s version, applied after the program (Caballero, 2012; Caballero-Blanco y Delgado-Noguera, 2014). The results obtained show that students and teachers has perceived a positive trend about responsibility development (associate to 5 responsibility levels). Therefore, it is possible con-cluded that the program has developed positive effects on CAFD’s student

Magnetic nanoparticles penetration and transport in planta

Resumen del póster presentado en la 9th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, celebrada en Minneapolis (Estados Unidos) del 22 al 26 de mayo de 2012.Magnetic nanoparticles are very suitable for a broad range of applications, like those involving synthesis and use of ferrofluids for bio-applications in general. In medicine the aim is to use them in diagnosis as well as in therapy. The ongoing research and results obtained up to now in these fields open a wide range of possibilities for using magnetic nanoparticles in other disciplines, for example in general plant research and agronomy. To study the use of nanoparticles in agriculture the first stage is to work out the penetration and transport into living plants and plant cells. We present here an overview of the research carried out within the scope of an interdisciplinary collaboration, on how inorganic nanoparticles interact with plant cells and tissues.

Programa del Congreso: La Psicología Social LLevada a la Vida Cotidiana

Este texto es Programa del Congreso "La Psicología Social Llevada a la Vida Cotidiana", celebrado en el marco de un proyecto de innovación docente financiado por la Unidad de Innovación Docente de la UCA. El congreso estaba dirigido, fundamentalmente, al alumnado que cursa, o ha cursado, alguna de las asignaturas del Área de Psicología Social. Se justifica la pertinencia de celebrar el mencionado congreso, se recoge la organización del mismo, y se muestra el contenido de la conferencia inaugural y un resumen de todas las aportaciones realizadas por el alumnado.Unidad de Innovación Docente de la Universidad de Cádiz.Número de páginas: 51. Editado exclusivamente en formato electrónico. Tamaño A4

IgAV and IgAN: a single entity regarding CD40, BLK and BANK1 polymorphisms.

Congresos y conferencias: Comunicación de congreso - oral

Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Withdrawal Is Associated with Higher Mortality in Hospitalized Patients with COVID-19

Our main aim was to describe the effect on the severity of ACEI (angiotensin-converting enzyme inhibitor) and ARB (angiotensin II receptor blocker) during COVID-19 hospitalization. A retrospective, observational, multicenter study evaluating hospitalized patients with COVID-19 treated with ACEI/ARB. The primary endpoint was the incidence of the composite outcome of prognosis (IMV (invasive mechanical ventilation), NIMV (non-invasive mechanical ventilation), ICU admission (intensive care unit), and/or all-cause mortality). We evaluated both outcomes in patients whose treatment with ACEI/ARB was continued or withdrawn. Between February and June 2020, 11,205 patients were included, mean age 67 years (SD = 16.3) and 43.1% female; 2162 patients received ACEI/ARB treatment. ACEI/ARB treatment showed lower all-cause mortality (p < 0.0001). Hypertensive patients in the ACEI/ARB group had better results in IMV, ICU admission, and the composite outcome of prognosis (p < 0.0001 for all). No differences were found in the incidence of major adverse cardiovascular events. Patients previously treated with ACEI/ARB continuing treatment during hospitalization had a lower incidence of the composite outcome of prognosis than those whose treatment was withdrawn (RR 0.67, 95%CI 0.63-0.76). ARB was associated with better survival than ACEI (HR 0.77, 95%CI 0.62-0.96). ACEI/ARB treatment during COVID-19 hospitalization was associated with protection on mortality. The benefits were greater in hypertensive, those who continue