Magnetic fabric of Pleistocene continental clays from the hanging-wall of an active low-angle normal fault (Altotiberina Fault, Italy)

Anisotropy of magnetic susceptibility (AMS) represents a valuable proxy able to detect subtle strain effects in very weakly deformed sediments. During the last decades a large number of AMS studies have documented that in compressive tectonic settings the maximum susceptibility axes (i.e. the magnetic lineations) are parallel to fold axes (and thrust faults) and local bedding strikes, while in extensional regimes they are perpendicular to the normal faults and, thus, parallel to the strata dip directions. One of the most striking active tectonic structures of the northern Apennines is represented by the Altotiberina Fault (ATF), a NE-dipping low-angle normal fault bounding the High Tiber Valley. The ATF represents a primary detachment of the Plio-Quaternary extensional tectonics affecting the Apennine belt. The long-lasting activity of the ATF produced 5 km of total displacement and up to 1200-m-thick basin infill of syn-tectonic, sandy-clayey continental succession. Thus, the AMS analysis of the sediments lying above the ATF represents a unique opportunity to document the strain field affecting the hanging-wall of low-angle normal faults. We collected 129 oriented cores at 12 different localities within the High Tiber Valley, and measured the AMS with a spinner Multi-Function Kappabridge. Most of the sites show a magnetic fabric typical of sediments at the earliest stages of deformation, characterized by oblate AMS ellipsoids and a well defined magnetic lineation, while prolate AMS ellipsoids at two sites are suggestive of pervasive tectonic effects. The magnetic lineation is well-developed at all sites and 20 has a prevailing N-S direction. At five sites the bedding is tilted and the magnetic lineation is subparallel to local bed-strikes, implying that these sites underwent a maximum horizontal shortening along an E-W direction. At two sites the magnetic lineation is sub-perpendicular to the trend of the ATF, and may be related to extensional strain. Our results reveal the existence of both compressional and extensional structures at the hangingwall of the ATF, and suggest that the early Pleistocene sequence of the High Tiber Valley is arranged in gently, local folds (hardly visible in the field) ~N-S trending. We interpret these compressivestructures as the result of local superficial stress induced by irregularities of the fault plane at depth. Accordingly, the strain field we documented from the High Tiber Valley can not be used to infer the regional tectonic regime acting during the ATF activity. We conclude that the long-lasting debate on the extensional vs. compressional Plio-Quaternary tectonics of the Apennines orogenic belt should be revised evaluating the importance of compressional structures resulting by local effects

Magnetic fabric of Pleistocene continental clays from the hanging-wall of an active low-angle normal fault (Altotiberina Fault, Italy)

Anisotropy of magnetic susceptibility (AMS) represents a valuable proxy able to detect subtle strain effects in very weakly deformed sediments. In compressive tectonic settings, the magnetic lineation is commonly parallel to fold axes, thrust faults, and local bedding strike, while in extensional regimes, it is perpendicular to normal faults and parallel to bedding dip directions. The Altotiberina Fault (ATF) in the northern Apennines (Italy) is a Plio-Quaternary NNW–SSE low-angle normal fault; the sedimentary basin (Tiber basin) at its hanging-wall is infilled with a syn-tectonic, sandy-clayey continental succession. We measured the AMS of apparently undeformed sandy clays sampled at 12 sites within the Tiber basin. The anisotropy parameters suggest that a primary sedimentary fabric has been overprinted by an incipient tectonic fabric. The magnetic lineation is well developed at all sites, and at the sites from the western sector of the basin it is oriented sub-perpendicular to the trend of the ATF, suggesting that it may be related to extensional strain. Conversely, the magnetic lineation of the sites from the eastern sector has a prevailing N–S direction. The occurrence of triaxial to prolate AMS ellipsoids and sub-horizontal magnetic lineations suggests that a maximum horizontal shortening along an E–W direction occurred at these sites. The presence of compressive AMS features at the hanging-wall of the ATF can be explained by the presence of gently N–Strending local folds (hardly visible in the field) formed by either passive accommodation above an undulated fault plane, or rollover mechanism along antithetic faults. The long-lasting debate on the extensional versus compressive Plio-Quaternary tectonics of the Apennines orogenic belt should now be revised taking into account the importance of compressive structures related to local effects

On the relevance of chaos for halo stars in the solar neighbourhood

We show that diffusion due to chaotic mixing in the neighbourhood of the Sun may not be as relevant as previously suggested in erasing phase space signatures of past Galactic accretion events. For this purpose, we analyse solar neighbourhood-like volumes extracted from cosmological simulations that naturally account for chaotic orbital behaviour induced by the strongly triaxial and cuspy shape of the resulting dark matter haloes, among other factors. In the approximation of an analytical static triaxial model, our results show that a large fraction of stellar halo particles in such local volumes have chaos onset times (i.e. the time-scale at which stars commonly associated with chaotic orbits will exhibit their chaotic behaviour) significantly larger than a Hubble time. Furthermore, particles that do present a chaotic behaviour within a Hubble time do not exhibit significant diffusion in phase space.Facultad de Ciencias Astronómicas y GeofísicasInstituto de Astrofísica de La Plat

Experimental evaluation of a recursive internetwork architecture prototype

The Recursive InterNetwork Architecture (RINA) is a recently proposed network architecture based on first principles, which promises to solve a number of issues present in the current Internet such as the lack of inherent security. In this paper, we present the experimental evaluation of the first performance-oriented implementation of RINA, the IRATI stack. Our open source stack is designed for GNU/Linux Operating Systems, with key components developed in kernel space for optimal performance. After briefly introducing the architecture, we present the main features of the stack, give some details about the implementation and discuss some trade-offs that had to be taken into account. We present use case scenarios for the evaluation, which were implemented in a test environment, and present the performance, achieving a goodput close to line rate on a GbE link, even when multiple Distributed Inter Process Communication Facilities (DIFs) are stacked

On the relevance of chaos for halo stars in the solar neighbourhood II

In a previous paper based on dark matter only simulations we show that, in the approximation of an analytic and static potential describing the strongly triaxial and cuspy shape of Milky Way-sized haloes, diffusion due to chaotic mixing in the neighbourhood of the Sun does not efficiently erase phase space signatures of past accretion events. In this second paper we further explore the effect of chaotic mixing using multicomponent Galactic potential models and solar neighbourhood-like volumes extracted from fully cosmological hydrodynamic simulations, thus naturally accounting for the gravitational potential associated with baryonic components, such as the bulge and disc. Despite the strong change in the global Galactic potentials with respect to those obtained in dark matter only simulations, our results confirm that a large fraction of halo particles evolving on chaotic orbits exhibit their chaotic behaviour after periods of time significantly larger than a Hubble time. In addition, significant diffusion in phase space is not observed on those particles that do exhibit chaotic behaviour within a Hubble time

On the relevance of chaos for halo stars in the solar neighbourhood II

In a previous paper based on dark matter only simulations we show that, in the approximation of an analytic and static potential describing the strongly triaxial and cuspy shape of Milky Way-sized haloes, diffusion due to chaotic mixing in the neighbourhood of the Sun does not efficiently erase phase space signatures of past accretion events. In this second paper we further explore the effect of chaotic mixing using multicomponent Galactic potential models and solar neighbourhood-like volumes extracted from fully cosmological hydrodynamic simulations, thus naturally accounting for the gravitational potential associated with baryonic components, such as the bulge and disc. Despite the strong change in the global Galactic potentials with respect to those obtained in dark matter only simulations, our results confirm that a large fraction of halo particles evolving on chaotic orbits exhibit their chaotic behaviour after periods of time significantly larger than a Hubble time. In addition, significant diffusion in phase space is not observed on those particles that do exhibit chaotic behaviour within a Hubble time

A tidally induced global corrugation pattern in an external disk galaxy similar to the milky way

We study the two-dimensional (2D) line-of-sight velocity (Vlos) field of the low-inclination, late-type galaxy VV304a. The resulting 2D kinematic map reveals a global, coherent, and extended perturbation that is likely associated with a recent interaction with the massive companion VV304b. We use multiband imaging and a suite of test-particle simulations to quantify the plausible strength of in-plane flows due to nonaxisymmetric perturbations and show that the observed velocity flows are much too large to be driven either by a spiral structure or by a bar. We use fully cosmological hydrodynamical simulations to characterize the contribution from in- and off-plane velocity flows to the Vlos field of recently interacting galaxy pairs like the VV304 system. We show that, for recently perturbed low-inclination galactic disks, the structure of the residual velocity field, after subtraction of an axisymmetric rotation model, can be dominated by vertical flows. Our results indicate that the Vlos perturbations in VV304a are consistent with a corrugation pattern. Its Vlos map suggests the presence of a structure similar to the Monoceros ring seen in the Milky Way. Our study highlights the possibility of addressing important questions regarding the nature and origin of vertical perturbations by measuring the line-of-sight velocities in low-inclination nearby galaxies

Hematopoietic Stem/Progenitor Cells Express Functional Mitochondrial Energy-Dependent Cystic Fibrosis Transmembrane Conductance Regulator

Bone marrow-derived hematopoietic stem/progenitor cells (HSPCs) encompass a wide array of cell subsets with different capacities of engraftment and injured tissue-regenerating potential. The characterization/isolation of the stem cell subpopulations represents a major challenge to improve the efficacy of transplantation protocols used in regenerative medicine. Cystic fibrosis (CF) is one of the diseases whose hope of cure relies on the successful application of cell-based gene therapy. This study was aimed at characterizing murine HSPCs on the basis of their bioenergetic competence and CF transmembrane conductance regulator (CFTR) expression. Positively immunoselected Sca-1(+) HSPCs encompassed 2 populations distinguished by their different size, Sca-1 expression and mitochondrial content. The smaller were the cells, the higher was Sca-1 expression and the lower was the intracellular density of functional mitochondria. Reverse transcription-polymerase chain reaction and western blotting revealed that HSPCs expressed CFTR mRNA and protein, which was also functional, as assessed by spectrofluorimetric and patch-clamp techniques. Inhibition of mitochondrial oxidative phosphorylation by oligomycin resulted in a 70% decrease of both the intracelluar adenosine triphosphate content and CFTR-mediated channel activity. Finally, HSPCs with lower Sca-1 expression and higher mitochondrial content displayed higher CFTR levels. Our findings identify 2 subpopulations in HSPCs and unveil a so-far unappreciated relationship between bioenergetic metabolism and CFTR in HSPC biology

Simulating cosmological substructure in the solar neighbourhood

We explore the predictive power of cosmological, hydrodynamical simulations for stellar phase-space substructure and velocity correlations with the auriga simulations and aurigaia mock Gaia catalogues. We show that at the solar circle the auriga simulations commonly host phase-space structures in the stellar component that have constant orbital energies and arise from accreted subhaloes. These structures can persist for a few Gyr, even after coherent streams in position space have been erased. We also explore velocity two-point correlation functions and find this diagnostic is not deterministic for particular clustering patterns in phase space. Finally, we explore these structure diagnostics with the aurigaia catalogues and show that current catalogues have the ability to recover some structures in phase space but careful consideration is required to separate physical structures from numerical structures arising from catalogue generation methods

Proxy evidence for state-dependence of climate sensitivity in the Eocene greenhouse

Despite recent advances, the link between the evolution of atmospheric CO2 and climate during the Eocene greenhouse remains uncertain. In particular, modelling studies suggest that in order to achieve the global warmth that characterised the early Eocene, warmer climates must be more sensitive to CO2 forcing than colder climates. Here, we test this assertion in the geological record by combining a new high-resolution boron isotope-based CO2 record with novel estimates of Global Mean Temperature. We find that Equilibrium Climate Sensitivity (ECS) was indeed higher during the warmest intervals of the Eocene, agreeing well with recent model simulations, and declined through the Eocene as global climate cooled. These observations indicate that the canonical IPCC range of ECS (1.5 to 4.5 °C per doubling) is unlikely to be appropriate for high-CO2 warm climates of the past, and the state dependency of ECS may play an increasingly important role in determining the state of future climate as the Earth continues to warm