43 research outputs found
El Servicio de Bibliotecas de la Universidad de Navarra
En 1952, de forma paralela a la creacioÌn de la Universidad de Navarra, hallamos el germen del Servicio de Bibliotecas. En este artiÌculo se hace una descripcioÌn de la historia del servicio y de sus principales funciones en la actualidad, haciendo una mencioÌn especial a la labor de su primer bibliotecario general, AÌlvaro dâOrs, quien disenÌoÌ y puso en marcha un modelo de biblioteca que sigue vigente. El apoyo a la docencia y a la investigacioÌn marcan el quehacer diario del personal del Servicio de Bibliotecas, cuyas funciones van evolucionando seguÌn lo hacen las necesidades del entorno acadeÌmico.1952an, Nafarroako Unibertsitatea sortzearekin batera, Liburutegiko Zerbitzuen lehe- nengo hazia jarri zen, 1960an zerbitzuari hasiera ofiziala eman zitzaiolarik. Artikulu honetan zerbitzuaren historia eta gaur egungo funtzioak laburtu ditugu, eta bertan, AÌlvaro dâOrs-en lana azpimarratu nahi izan dugu batez ere. DâOrs lehenengo Liburu- zain Orokorra izan zen eta gaur egun dugun liburutegia diseinatu eta martxan jarri zuen. Liburutegi zerbitzuaren lan nagusia irakaskuntza eta ikerketa arloan gure lagun- tza eskaintzea da, eta horrekin batera, ingurune akademikoan ager daitezkeen beharrei erantzuna ematea.The origin of the Library Service of the University of Navarra is in 1952, coinciding with the start of the University. This article describes the history of the service and its main functions at present â and, in particular, the work of the first General Librarian, AÌlvaro dâOrs, who designed and launched a library model that is still in operation today. Teaching and research support are hallmarks of the day-to-day activities of Library Services staff, whose roles have evolved in response to changes in the academic environment
Specific and reversible immobilization of proteins tagged to the affinity polypeptide C-LytA on functionalized graphite electrodes
We have developed a general method for the specific and reversible immobilization of proteins fused to the choline-binding module C-LytA on functionalized graphite electrodes. Graphite electrode surfaces were modified by diazonium chemistry to introduce carboxylic groups that were subsequently used to anchor mixed self-assembled monolayers consisting of N,N-diethylethylenediamine groups, acting as choline analogs, and ethanolamine groups as spacers. The ability of the prepared electrodes to specifically bind C-LytA-tagged recombinant proteins was tested with a C-LytA-ÎČ-galactosidase fusion protein. The binding, activity and stability of the immobilized protein was evaluated by electrochemically monitoring the formation of an electroactive product in the enzymatic hydrolysis of the synthetic substrate 4-aminophenyl ÎČ-D-galactopyranoside. The hybrid protein was immobilized in an specific and reversible way, while retaining the catalytic activity. Moreover, these functionalized electrodes were shown to be highly stable and reusable. The method developed here can be envisaged as a general, immobilization procedure on the protein biosensor field.This work was supported by grants BFU2010â17824, CTQ2008-04492-E and CTQ2010-18570 (Spanish Ministerio de Economia y Competitividad) and FPA-2010-055 (Valentian Government, Spain)
Enhancing the First-Pass Effect in Acute Stroke: The Impact of Stent Retriever Characteristics
Introduction: Although stentrievers (SRs) have been a mainstay of mechanical thrombectomy (MT), and current guidelines recommend the use of SRs in the treatment of large vessel occlusion stroke (LVO), there is a paucity of studies in the literature comparing SRs directly against each other in terms of mechanical and functional properties. Timely access to endovascular therapy and the ability to restore intracranial flow in a safe, efficient, and efficacious manner have been critical to the success of MT. This study aimed to investigate the impact of contemporary SR characteristics, including model, brand, size, and length, on the first-pass effect (FPE) in patients with acute ischemic stroke. Methods: Consecutive patients with M1 occlusion treated with a single SR+BGC were recruited from the ROSSETTI registry. The primary outcome was the FPE that was defined as modified (mFPE) or true (tFPE) for the achievement of modified thrombolysis in cerebral infarction (mTICI) grades 2b-3 or 3 after a single device pass, respectively. We compared patients who achieved mFPE with those who achieved tFPE according to SR characteristics. Results: We included 610 patients (52.3% female and 47.7% male, mean age 75.1 +/- 13.62 years). mFPE was achieved in 357 patients (58.5%), whereas tFPE was achieved in 264 (43.3%). There was no significant association between SR characteristics and mFPE or tFPE. Specifically, the SR size did not show a statistically significant relationship with improvement in FPE. Similarly, the length of the SR did not yield significant differences in the mFPE and tFPE, even when the data were grouped. Conclusions: Our data indicate that contemporary SR-mediated thrombectomy characteristics, including model, brand, size, and length, do not significantly affect the FPE
Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron
The CDF and D0 experiments at the Fermilab Tevatron have measured the asymmetry between yields of forward- and backward-produced top and antitop quarks based on their rapidity difference and the asymmetry between their decay leptons. These measurements use the full data sets collected in proton-antiproton collisions at a center-of-mass energy of TeV. We report the results of combinations of the inclusive asymmetries and their differential dependencies on relevant kinematic quantities. The combined inclusive asymmetry is . The combined inclusive and differential asymmetries are consistent with recent standard model predictions
Gestão Estratégica de Pessoas E Desempenho Organizacional - Uma Anålise Teórica
Este artigo, de carĂĄter teĂłrico, realizou uma breve revisĂŁo da literatura especializada no campo da gestĂŁo de pessoas, apresentando os principais conceitos, teorias e abordagens relacionadas Ă gestĂŁo estratĂ©gica de pessoas e, tambĂ©m, sobre a relação da gestĂŁo de pessoas com o desempenho organizacional. O presente artigo se justifica em termos de sua tentativa de compreensĂŁo do papel especĂfico da gestĂŁo de pessoas na dinĂąmica organizacional contemporĂąnea, assim como dos reflexos dessa dinĂąmica no desempenho e eficĂĄcia das organizaçÔes. Foram apresentados os principais conceitos e elementos constituintes das teorias, assim como, foram apresentadas e discutidas algumas relaçÔes entre as diferentes abordagens utilizadas. Ao final, constatou-se que o tema apresenta limitaçÔes teĂłricas e metodolĂłgicas significativas e que a tarefa de mensurar a agregação de valor do capital humano, ou do impacto da gestĂŁo de pessoas sobre o desempenho das organizaçÔes nĂŁo Ă© simples, requerendo novas perspectivas teĂłricas e metodolĂłgicas.</p
Gestão Estratégica de Pessoas E Desempenho Organizacional - Uma Anålise Teórica
Este artigo, de carĂĄter teĂłrico, realizou uma breve revisĂŁo da literatura especializada no campo da gestĂŁo de pessoas, apresentando os principais conceitos, teorias e abordagens relacionadas Ă gestĂŁo estratĂ©gica de pessoas e, tambĂ©m, sobre a relação da gestĂŁo de pessoas com o desempenho organizacional. O presente artigo se justifica em termos de sua tentativa de compreensĂŁo do papel especĂfico da gestĂŁo de pessoas na dinĂąmica organizacional contemporĂąnea, assim como dos reflexos dessa dinĂąmica no desempenho e eficĂĄcia das organizaçÔes. Foram apresentados os principais conceitos e elementos constituintes das teorias, assim como, foram apresentadas e discutidas algumas relaçÔes entre as diferentes abordagens utilizadas. Ao final, constatou-se que o tema apresenta limitaçÔes teĂłricas e metodolĂłgicas significativas e que a tarefa de mensurar a agregação de valor do capital humano, ou do impacto da gestĂŁo de pessoas sobre o desempenho das organizaçÔes nĂŁo Ă© simples, requerendo novas perspectivas teĂłricas e metodolĂłgicas
The Hα-based star formation rate density of the universe at z=0.84
We present the results of an Hα near-infrared narrowband survey searching for star-forming galaxies at redshift z = 0.84. This work is an extension of our previous narrowband studies in the optical at lower redshifts. After removal of stars and redshift interlopers (using spectroscopic and photometric redshifts), we build a complete sample of 165 Hα emitters in the extended Groth strip and GOODS-N fields with L(Hα) > 10^41 ergs s^â1. We compute the Hα luminosity function at z = 0.84 after corrections for [N_Ï] flux contamination, extinction, systematic errors, and incompleteness. Our sources present an average dust extinction of A(H α) = 1.5 mag. Adopting Hα as a surrogate for the instantaneous SFR, we measure an extinction-corrected SFR density of 0.17^+0.03_â0.03 M_â yr^â1 Mpc^â3. Combining this result to our prior measurements at z = 0.02, 0.24, and 0.40, we derive an Hα-based evolution of the SFR density proportional to (1 + z)^ÎČ with ÎČ = 3.8 ± 0.5. This evolution is consistent with that derived by other authors using different SFR tracers
Shards: an optical spectro-photometric survey of distant galaxies
We present the Survey for High-z Absorption Red and Dead Sources (SHARDS), an ESO/GTC Large Program carried out using the OSIRIS instrument on the 10.4 m Gran Telescopio Canarias (GTC). SHARDS is an ultra-deep optical spectro-photometric survey of the GOODS-N field covering 130 arcmin(2) at wavelengths between 500 and 950 nm with 24 contiguous medium-band filters (providing a spectral resolution R similar to 50). The data reach an AB magnitude of 26.5 (at least at a 3 sigma level) with sub-arcsec seeing in all bands. SHARDS' main goal is to obtain accurate physical properties of intermediate-and high-z galaxies using well-sampled optical spectral energy distributions (SEDs) with sufficient spectral resolution to measure absorption and emission features, whose analysis will provide reliable stellar population and active galactic nucleus (AGN) parameters. Among the different populations of high-z galaxies, SHARDS' principal targets are massive quiescent galaxies at z > 1, whose existence is one of the major challenges facing current hierarchical models of galaxy formation. In this paper, we outline the observational strategy and include a detailed discussion of the special reduction and calibration procedures which should be applied to the GTC/OSIRIS data. An assessment of the SHARDS data quality is also performed. We present science demonstration results on the detection and study of emission-line galaxies (star-forming objects and AGNs) at z = 0-5. We also analyze the SEDs for a sample of 27 quiescent massive galaxies with spectroscopic redshifts in the range 1.0 < z less than or similar to 1.4. We discuss the improvements introduced by the SHARDS data set in the analysis of their star formation history and stellar properties. We discuss the systematics arising from the use of different stellar population libraries, typical in this kind of study. Averaging the results from the different libraries, we find that the UV-to-MIR SEDs of the massive quiescent galaxies at z = 1.0-1.4 are well described by an exponentially decaying star formation history with scale t = 100-200 Myr, age around 1.5-2.0 Gyr, solar or slightly sub-solar metallicity, and moderate extinction, A(V) similar to 0.5 mag. We also find that galaxies with masses above M* are typically older than lighter galaxies, as expected in a downsizing scenario of galaxy formation. This trend is, however, model dependent, i.e., it is significantly more evident in the results obtained with some stellar population synthesis libraries, and almost absent in others