3,312 research outputs found
Quantifying Long-Term Changes in Carbon Stocks and Forest Structure from Amazon Forest Degradation
Despite sustained declines in Amazon deforestation, forest degradation from logging and firecontinues to threaten carbon stocks, habitat, and biodiversity in frontier forests along the Amazon arcof deforestation. Limited data on the magnitude of carbon losses and rates of carbon recoveryfollowing forest degradation have hindered carbon accounting efforts and contributed to incompletenational reporting to reduce emissions from deforestation and forest degradation (REDD+). Wecombined annual time series of Landsat imagery and high-density airborne lidar data to characterizethe variability, magnitude, and persistence of Amazon forest degradation impacts on abovegroundcarbon density (ACD) and canopy structure. On average, degraded forests contained 45.1% of thecarbon stocks in intact forests, and differences persisted even after 15 years of regrowth. Incomparison to logging, understory fires resulted in the largest and longest-lasting differences in ACD.Heterogeneity in burned forest structure varied by fire severity and frequency. Forests with a historyof one, two, and three or more fires retained only 54.4%, 25.2%, and 7.6% of intact ACD,respectively, when measured after a year of regrowth. Unlike the additive impact of successive fires,selective logging before burning did not explain additional variability in modeled ACD loss andrecovery of burned forests. Airborne lidar also provides quantitative measures of habitat structure thatcan aid the estimation of co-benefits of avoided degradation. Notably, forest carbon stocks recoveredfaster than attributes of canopy structure that are critical for biodiversity in tropical forests, includingthe abundance of tall trees. We provide the first comprehensive look-up table of emissions factors forspecific degradation pathways at standard reporting intervals in the Amazon. Estimated carbon lossand recovery trajectories provide an important foundation for assessing the long-term contributionsfrom forest degradation to regional carbon cycling and advance our understanding of the currentstate of frontier forests
Relevância da Infecção VHC em Coagulopatias Congénitas
Introdução: A infecção pelo vírus da hepatite C (VHC) em doentes com coagulopatias congénitas (CC), como consequência da terapêutica empregue entre os anos 70 e 80 com transfusão de derivados de plasma humano, constitui um problema de saúde substancial e relevante.
Objectivos: Análise e avaliação da relevância representada pela infecção VHC e suas complicações no tratamento duma população de doentes com CC.
Métodos: Análise retrospectiva duma série de 161 doentes com CC tratados no Serviço de Imunohemoterapia do Centro Hospitalar de Lisboa Central (Lisboa, Portugal). Revisão sistemática de processos clínicos. Elaboração duma base de dados compreendendo a informação reunida e estudo estatístico das suas variáveis: idade, género, tipo e gravidade da coagulopatia e modalidade de tratamento. Relativamente à infecção por VHC: genotipo, tipo e duração do tratamento, frequência de resposta mantida ao tratamento e recidiva, co-infecções e complicações major e minor.
Resultados: Dos 161 doentes 65 (40%) estão infectados pelo VHC. Dos doentes com hemofilia A: 36% são grave e 62% dos quais estão infectados pelo VHC; 9% moderada com 57%; 25% ligeira com 20%. No grupo da hemofilia B: 8% são grave com 23% infectados e 6% moderada ou ligeira com 10%. Relativamente ao grupo com doença de von Willebrand: 12% são tipo 2 com 16% infectados e 4% tipo 3 com 86%. Uma coorte de 26 doentes foi submetida a terapêutica para a infecção pelo VHC, com o primeiro doente a receber tratamento em 1993. Destes, 5 eram seropositivos para o VIH. O tratamento variou de monoterapia com interferão a terapêutica combinada de interferão ou interferão-peguilado com ribavirina.
Conclusões: A infecção pelo VHC representa uma complicação significativa do tratamento empregue no passado na população em estudo. Considerando que a maioria destes doentes foi infectada nos finais dos anos 70 e início dos anos 80 assim como a evolução natural da infecção pelo VHC em doentes sem CC, prevê-se que a prevalência de complicações major deverá aumentar significativamente nos próximos anos. É de suma importância a implementação de medidas profilácticas na revisão e adaptação dos protocolos de seguimento de forma a prevenir a progressão da patologia hepática nestes doentes
Women living with HIV/AIDS who are sexual partners of injecting drug users
OBJECTIVE: To analyze perceptions of risk, prevention strategies, their own relationship with drug use and that of their partner's, and future expectations among women living with HIV/AIDS whose partners are drug users. METHODS: This is a qualitative study of women living with HIV/AIDS who receive specialist treatment in São Paulo Municipality. Semi-structured interviews were carried out with 15 women, whose self-reported means of infection were heterosexual relations with a partner who is an injecting drug user. The script for the interviews covered the following areas: childhood, history of sexual relations, use of drugs, impact of seropositivity on daily life, understanding of the prevention of sexually transmitted infections, and perspectives of the future. The material from the interviews was analyzed using content analysis. RESULTS: The study pointed to a difference in the ways that the women live with their own drug use and with that of their partners. Their partners' use of injecting drugs was not primarily associated with a risk of HIV infection, due to attempts to conceal the fact or because they believed that the monogamy-fidelity-confidence trinity would take precedence as a form of protection. CONCLUSIONS: The women's different experiences of drug use should be taken into account and opportunities to discuss with them about the issue are important to ensure that more effective strategies for prevention and care are adopted.OBJETIVO: Analisar as percepções de risco, as estratégias de prevenção, sua própria relação com o uso de drogas e do parceiro e suas expectativas quanto ao futuro relatadas por mulheres vivendo com HIV/Aids parceiras de usuários de drogas. MÉTODOS: Estudo qualitativo sobre mulheres vivendo com HIV/Aids, atendidas em serviço especializado no Município de São Paulo. Foram aplicadas entrevistas semi-estruturadas a 15 mulheres, cuja via de infecção auto-referida foram as relações heterossexuais com parceiro usuário de drogas injetáveis. O roteiro das entrevistas compreendia: infância, história dos relacionamentos amorosos, uso de drogas, impacto da soropositividade no cotidiano, compreensão sobre prevenção de infecções sexualmente transmissíveis, e visão do futuro. A interpretação das entrevistas foi realizada por meio de análise de conteúdo. RESULTADOS: O estudo indicou diversidade da convivência das mulheres com o uso de drogas próprio e do parceiro. O uso de drogas injetáveis pelo parceiro não foi, prioritariamente, associado ao risco de infecção por HIV/Aids, seja por estratégias de ocultamento do fato, seja por considerarem que a tríade monogamia-fidelidade-confiança teria primazia como forma de proteção. CONCLUSÕES: A diversidade da convivência das mulheres com o uso de drogas deve ser considerada e oportunidades de fala e escuta sobre a questão podem ser importantes para a adoção de estratégias mais efetivas de prevenção e cuidado.Universidade de São Paulo Faculdade de Medicina Departamento de Medicina PreventivaUniversidade Federal de São Paulo (UNIFESP) Departamento de Ciências da SaúdePrefeitura Municipal de São Paulo Secretaria Municipal de SaúdeUNIFESP, Depto. de Ciências da SaúdeSciEL
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Recent developments and applications of the chiral Brønsted acid catalyzed allylboration of carbonyl compounds
The 50-year-old allylboration reaction has seen dramatic developments since the dawn of the new century after the first catalytic asymmetric versions came into play. In the past decade alone, several methodologies capable of achieving the desired homoallylic alcohols in over 90% e.e. have been developed. This review focuses on the chiral Brønsted acid-catalyzed allylboration reaction—covering everything from the very first examples and precedents to modern day variations and applications—and includes the following sections:
1. Introduction
2. Early developments
3. Synthetic applications
4. Variants
5. Computational contributionWe thank the Spanish MINECO (CTQ2013-43310) and Generalitat
Valenciana (PROMETEOII/2014/073) for their financial support. D. M. S.
is grateful to the Spanish Government for an FPU fellowship. We are
grateful to Girton College, Cambridge (Research Fellowship to M.N.G.) for
financial support
Interdependent network reciprocity in evolutionary games
Besides the structure of interactions within networks, also the interactions between networks are of the outmost
importance. We therefore study the outcome of the public goods game on two interdependent networks that are
connected by means of a utility function, which determines how payoffs on both networks jointly influence the
success of players in each individual network. We show that an unbiased coupling allows the spontaneous
emergence of interdependent network reciprocity, which is capable to maintain healthy levels of public
cooperation even in extremely adverse conditions. The mechanism, however, requires simultaneous formation of
correlated cooperator clusters on both networks. If this does not emerge or if the coordination process is
disturbed, network reciprocity fails, resulting in the total collapse of cooperation. Network interdependence can
thus be exploited effectively to promote cooperation past the limits imposed by isolated networks, but only if the
coordination between the interdependent networks is not disturbe
If players are sparse social dilemmas are too: Importance of percolation for evolution of cooperation
Spatial reciprocity is a well known tour de force of cooperation promotion. A
thorough understanding of the effects of different population densities is
therefore crucial. Here we study the evolution of cooperation in social
dilemmas on different interaction graphs with a certain fraction of vacant
nodes. We find that sparsity may favor the resolution of social dilemmas,
especially if the population density is close to the percolation threshold of
the underlying graph. Regardless of the type of the governing social dilemma as
well as particularities of the interaction graph, we show that under pairwise
imitation the percolation threshold is a universal indicator of how dense the
occupancy ought to be for cooperation to be optimally promoted. We also
demonstrate that myopic updating, due to the lack of efficient spread of
information via imitation, renders the reported mechanism dysfunctional, which
in turn further strengthens its foundations.Comment: 6 two-column pages, 5 figures; accepted for publication in Scientific
Reports [related work available at http://arxiv.org/abs/1205.0541
Age and growth of the smooth hammerhead, Sphyrna zygaena, in the Atlantic Ocean: comparison with other hammerhead species
The smooth hammerhead Sphyrna zygaena (Sphyrnidae) is a pelagic shark occasionally caught as bycatch in pelagic longline fisheries, but is one of the least studied of all pelagic sharks. Age and growth of S. zygaena was studied along a wide Atlantic region covering both the northern and southern hemispheres. Data from 304 specimens, caught between October 2009 and September 2014, ranging in size from 126 to 253 cm fork length (FL), were analysed. Growth models were fitted using the three-parameter von Bertalanffy growth function (VBGF) re-parameterized to calculate L0 (size at birth). Growth models were fitted to the sample data and data from several back-calculation models. The model fit to the quadratic modified Dahl-Lea back-calculated data seems to be the most appropriate to describe growth in this species, with resulting growth parameters of Linf = 285 cm FL, k = 0.09 year−1 for males and Linf = 293 cm FL, k = 0.09 year−1 for females. Compared with other species of the same genus, estimated growth coefficients for S. zygaena seem to fall in the low to middle range. Although further work is still needed, this study adds to knowledge of the vital life-history parameters of smooth hammerheads in the Atlantic Ocean, which can be used in the management and conservation of this species.Programa Operacional Potencial Humano: IF/00253/2014info:eu-repo/semantics/publishedVersio
Towards an in-depth understanding of physical activity and eating behaviours during COVID-19 social confinement: A combined approach from a Portuguese National Survey
Rapid worldwide decreases in physical activity (PA), an increase in sedentary behaviour (SB) and poorer dietary patterns have been reported during COVID-19 confinement periods. However, as national variability has been observed, this study sought to describe PA, SB and eating patterns, and to explore their gender as well as other socio-demographic correlates and how they interrelate in a representative sample of Portuguese adults during the COVID-19 first mandatory social confinement. The survey was applied online and by telephone to 5856 adults (mean age = 45.8 years; 42.6% women). The majority reported high (46.0%) or moderate (20.5%) PA levels. Men, younger participants, those with higher education levels and a favourable perception of their financial situation reported higher PA levels, with the opposite pattern for SB. Physical fitness activities and household chores were more reported by women, with more strength training and running activities reported by men. Regarding eating behaviours, 45.1% reported changes, positive (58%) and negative (42%), with 18.2% reporting increases in consumption of fruit, vegetables, and fish and other seafood consumption, while 10.8% (most with lower educational level and less comfortable with their income) reported an increase in consumption of ready-to-eat meals, soft drinks, savoury snacks, and take-away and delivered meals. Two clustersa health-enhancing vs. risky patternemerged through multiple correspondence analysis characterized by co-occurrence of high vs. low PA levels, positive vs. negative eating changes, awareness or not of the COVID-19 PA and dietary recommendations, perceived financial situation, higher vs. lower educational level and time in social confinement. In conclusion, while in social confinement, both positive and negative PA and eating behaviours and trends were displayed, highlighting the role of key sociodemographic correlates contributing to healthy vs. risky patterns. Results may inform future health interventions and policies to be more targeted to those at risk, and also advocate the promotion of PA and healthy eating in an integrated fashion.</jats:p
Optimal interdependence between networks for the evolution of cooperation
Recent research has identified interactions between networks as crucial for the outcome of evolutionary
games taking place on them. While the consensus is that interdependence does promote cooperation by
means of organizational complexity and enhanced reciprocity that is out of reach on isolated networks, we
here address the question just how much interdependence there should be. Intuitively, one might assume
the more the better. However, we show that in fact only an intermediate density of sufficiently strong
interactions between networks warrants an optimal resolution of social dilemmas. This is due to an intricate
interplay between the heterogeneity that causes an asymmetric strategy flow because of the additional links
between the networks, and the independent formation of cooperative patterns on each individual network.
Presented results are robust to variations of the strategy updating rule, the topology of interdependent
networks, and the governing social dilemma, thus suggesting a high degree of universality
Modeling the risk of malaria for travelers to areas with stable malaria transmission
BACKGROUND: Malaria is an important threat to travelers visiting endemic regions. The risk of acquiring malaria is complex and a number of factors including transmission intensity, duration of exposure, season of the year and use of chemoprophylaxis have to be taken into account estimating risk. MATERIALS AND METHODS: A mathematical model was developed to estimate the risk of non-immune individual acquiring falciparum malaria when traveling to the Amazon region of Brazil. The risk of malaria infection to travelers was calculated as a function of duration of exposure and season of arrival. RESULTS: The results suggest significant variation of risk for non-immune travelers depending on arrival season, duration of the visit and transmission intensity. The calculated risk for visitors staying longer than 4 months during peak transmission was 0.5% per visit. CONCLUSIONS: Risk estimates based on mathematical modeling based on accurate data can be a valuable tool in assessing risk/benefits and cost/benefits when deciding on the value of interventions for travelers to malaria endemic regions
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