Modeling Coordinated vs. P2P Mining: An Analysis of Inefficiency and Inequality in Proof-of-Work Blockchains

We study efficiency in a proof-of-work blockchain with non-zero latencies, focusing in particular on the (inequality in) individual miners' efficiencies. Prior work attributed differences in miners' efficiencies mostly to attacks, but we pursue a different question: Can inequality in miners' efficiencies be explained by delays, even when all miners are honest? Traditionally, such efficiency-related questions were tackled only at the level of the overall system, and in a peer-to-peer (P2P) setting where miners directly connect to one another. Despite it being common today for miners to pool compute capacities in a mining pool managed by a centralized coordinator, efficiency in such a coordinated setting has barely been studied. In this paper, we propose a simple model of a proof-of-work blockchain with latencies for both the P2P and the coordinated settings. We derive a closed-form expression for the efficiency in the coordinated setting with an arbitrary number of miners and arbitrary latencies, both for the overall system and for each individual miner. We leverage this result to show that inequalities arise from variability in the delays, but that if all miners are equidistant from the coordinator, they have equal efficiency irrespective of their compute capacities. We then prove that, under a natural consistency condition, the overall system efficiency in the P2P setting is higher than that in the coordinated setting. Finally, we perform a simulation-based study to demonstrate that even in the P2P setting delays between miners introduce inequalities, and that there is a more complex interplay between delays and compute capacities

Dari Teacher Centered Learning menuju Student Centered Learning (studi kasus tetntang proses pembelajaran di SMAN N I MANYARAN )

dari teacher centered learning menuju student centered learning ( studi kasus tentang proses pembelajaran di SMA N I Manyara

A protocol for large scale genomic DNA isolation for cacao genetics analysis

Advances in DNA technology, such as marker assisted selection, detection of quantitative trait loci and genomic selection also require the isolation of DNA from a large number of samples and the preservation of tissue samples for future use in cacao genome studies. The present study proposes a method for the preservation of sample tissues for DNA extraction and for manual extraction of large number of samples using spheres. The integrity and concentration of the DNA by these methods were assessed and compared with conventional method using mortar. The best parameters in order to obtain a fine powder using spheres was the use of 4 lyophilized leaf disks (50 mg), a single steel ball of 6 mm in diameter, followed by 30 s of manual maceration. The quantity of DNA obtained was four times higher than the conventional method. The purity of the DNA obtained was satisfactory and proved to be amplifiable by PCR using SSR primers. The present approach is a reliable, rapid, simple and consistent DNA isolation method for cacao, compared to the conventional methods. The protocol greatly increases the efficiency of extraction and suggests an inexpensive and practical way of DNA isolation of cacao for large scale.Keywords: DNA extraction, cacao, spheres, lyophilized

Optical, near-IR and sub-mm IFU Observations of the nearby dual AGN Mrk 463

We present optical and near-IR Integral Field Unit (IFU) and ALMA band 6 observations of the nearby dual Active Galactic Nuclei (AGN) Mrk 463. At a distance of 210 Mpc, and a nuclear separation of $\sim$4 kpc, Mrk 463 is an excellent laboratory to study the gas dynamics, star formation processes and supermassive black hole (SMBH) accretion in a late-stage gas-rich major galaxy merger. The IFU observations reveal a complex morphology, including tidal tails, star-forming clumps, and emission line regions. The optical data, which map the full extent of the merger, show evidence for a biconical outflow and material outflowing at $>$600 km s$^{-1}$, both associated with the Mrk 463E nucleus, together with large scale gradients likely related to the ongoing galaxy merger. We further find an emission line region $\sim$11 kpc south of Mrk 463E that is consistent with being photoionized by an AGN. Compared to the current AGN luminosity, the energy budget of the cloud implies a luminosity drop in Mrk 463E by a factor 3-20 over the last 40,000 years. The ALMA observations of $^{12}$CO(2-1) and adjacent 1mm continuum reveal the presence of $\sim$10$^{9}$M$_\odot$ in molecular gas in the system. The molecular gas shows velocity gradients of $\sim$800 km/s and $\sim$400 km/s around the Mrk 463E and 463W nuclei, respectively. We conclude that in this system the infall of $\sim$100s $M_\odot$/yr of molecular gas is in rough balance with the removal of ionized gas by a biconical outflow being fueled by a relatively small, $<$0.01% of accretion onto each SMBH.Comment: Accepted by The Astrophysical Journal, 23 pages, 19 figure

Are bioelectrical parameters and functionality associated with postural control in the elderly?

Background: Alterations in bioimpedance parameters and postural control occur with aging and contribute to the increased risk of falls. The aim of this study was to evaluate the balance behavior in relation to bioimpedance and functionality. Methods: We evaluated 21 elderly (men: 77.3 ± 9.5 years; women: 74.2 ± 9.6 years). The balance in standing posture was measured by the movement of the pressure center in seven positions. Bioimpedance was defined by its parameters resistance, reactance and phase angle, and functionality through the Timed Up and Go Test and Short Physical Performance Battery. Findings: In the analysis of the mediolateral velocity at the positions feet separated with open and closed eyes, feet together with eyes closed and semi-tandem with eyes open on the platform, an inverse correlation between balance and bioimpedance variables were verified for all models, with a coefficient of determination varying between 20% and 74%. Inverse and significant correlations between reactance and phase angle in the one-legged-support position were verified, in all adjustment models, with coefficient of determination varying between 62% and 91%. In the analysis of mediolateral velocity for the semi-tandem eyes closed position, positive correlation with TUG and an inverse correlation with bioimpedance parameters and pennation angle were observed, with coefficient of determination varying between 21% and 67%. Interpretation: The postural control is linearly related to bioimpedance parameters and functionality in the elderly. The assessment of balance can provide important information and furnishes useful insights for prevention and treatment strategies in elderly

The health of women and girls determines the health and well-being of our modern world: A White Paper From the International Council on Women's Health Issues

The International Council on Women's Health Issues (ICOWHI) is an international nonprofit association dedicated to the goal of promoting health, health care, and well-being of women and girls throughout the world through participation, empowerment, advocacy, education, and research. We are a multidisciplinary network of women's health providers, planners, and advocates from all over the globe. We constitute an international professional and lay network of those committed to improving women and girl's health and quality of life. This document provides a description of our organization mission, vision, and commitment to improving the health and well-being of women and girls globally

Dissecting Photometric redshift for Active Galactic Nuclei using XMM- and Chandra-COSMOS samples

With this paper, we release accurate photometric redshifts for 1692 counterparts to Chandra sources in the central square degree of the COSMOS field. The availability of a large training set of spectroscopic redshifts that extends to faint magnitudes enabled photometric redshifts comparable to the highest quality results presently available for normal galaxies. We demonstrate that morphologically extended, faint X-ray sources without optical variability are more accurately described by a library of normal galaxies (corrected for emission lines) than by AGN-dominated templates, even if these sources have AGN-like X-ray luminosities. Preselecting the library on the bases of the source properties allowed us to reach an accuracy sigma_(Delta z/(1+z_spec)) \sim0.015 with a fraction of outliers of 5.8% for the entire Chandra-COSMOS sample. In addition, we release revised photometric redshifts for the 1735 optical counterparts of the XMM-detected sources over the entire 2 sq. deg.of COSMOS. For 248 sources, our updated photometric redshift differs from the previous release by Delta z>0.2. These changes are predominantly due to the inclusion of newly available deep H-band photometry H_AB=24 mag. We illustrate once again the importance of a spectroscopic training sample and how an assumption about the nature of a source together with the number and the depth of the available bands influence the accuracy of the photometric redshifts determined for AGN. These considerations should be kept in mind when defining the observational strategies of upcoming large surveys targeting AGN, such as eROSITA at X-ray energies and ASKAP/EMU in the radio band.Comment: ApJ, accepted for publication. Data also available at http://www.ipp.mpg.de/~msalv/PHOTOZ_XCOSMO

Degree of conversion of different composite resins photo-activated with light-emitting diode and argon ion laser

This study evaluated the degree of conversion (DC%) of one experimental and different brands of composite resins light-cured by two light sources (one LED and one argon laser). The percentage of unreacted C = C was determined from the ratio of absorbance intensities of aliphatic C = C (peak at 1637 cm−1) against internal standards before and after curing: aromatic C–C (peak at 1610 cm−1) except for P90, where %C = C bonds was given for C–O–C (883 cm−1) and C–C (1257 cm−1). ANOVA and Tukey’s test revealed no statistically significant difference among Z350 (67.17), Z250 (69.52) and experimental (66.61 ± 2.03) with LED, just among them and Evolu-X (75.51) and P90 (32.05) that showed higher and lower DC%, respectively. For the argon laser, there were no differences among Z250 (70.67), Z350 (69.60), experimental (65.66) and Evolu-X (73, 37), however a significant difference was observed for P90 (36.80), which showed lowest DC%. The light sources showed similar DC%, however the main difference was observed regarding the composite resins. The lowest DC% was observed for the argon laser. P90 showed the lowest DC% for both light-curing sources