Клиническая эффективность применения альфа-адреноблокаторов и магнито-лазерной терапии в комплексном лечении больных мочекаменной болезнью

Possibility of spontaneous concretion discharge from ureter in many ways depends on efficiency of administered conservative therapy. According to the studies of several authors, confirming the presence of a1-adrenoceptors in the ureter wall, in our study we used a1-blocker tamsulosin. The probability of spontaneous concretion discharge from ureter using low intensive laser therapy and Tamsulosin increases in 3 times. It was showed that combination of low intensive laser therapy and Tamsulosin resulted to spontaneous discharge of the larger concrements comparing with traditional therapy and may be recommended for clinical practice.Вероятность самостоятельного отхождения конкрементов из просвета мочеточников во многом зависит от эффективности проводимой консервативной терапии. В связи с этим актуальным вопросом является поиск патогенетически обоснованных современных методов литокинетичекой терапии. С этой целью, учитывая исследования ряда авторов, подтверждающих наличие в стенке мочеточника a1-адренорецепторов, в нашем исследовании использовался a1-адреноблокатор Тамсулозин. Вероятность самостоятельного отхождения конкрементов из мочеточников на фоне проведения низкоинтенсивной лазерной терапии и приема препарата Тамсулозин возрастает в 3 раза. При этом следует отметить, что на фоне проведения низкоинтенсивной лазерной терапии и приема препарата Тамсулозин происходит самостоятельное отхождение более крупных конкрементов, чем на фоне обычной спазмолитической терапии, что позволяет рекомендовать разработанную в клинике методику к применению в клинической практике

Прогностическое значение кровотока предстательной железы у больных острой задержкой мочеиспускания на фоне доброкачественной гиперплазии предстательной железы

Benign prostatic hyperplasia is the most frequent disease among middle and old aged men. The purpose of our study is to assess the efficiency of diagnosis of benign prostatic hyperplasia (BPH) without complications and with urine retention. Transrectal sonography was performed in 77 patients with BPH. The estimation of blood flow in patients of main group performed with transrectal ultrasound with Doppler. The speed of blood flow measured in subcapsular and paraurethral arteries with estimation of diameter and speed of vein drain in the paraprostatic veins. Transrectal sonography showed the changes in the prostatic blood-flow especially in case of urine retention. Transrectal ultrsonography playys an important role in the evaluation of the prostatic blood-flow.Доброкачественная гиперплазия предстательной железы (ДГПЖ) является чрезвычайно распространенным заболеванием. Клинические признаки ДГПЖ обнаруживаются у 14% мужчин в возрасте 40-49 лет и у 90% в возрасте 80 лет. Одним из частых осложнений ДГПЖ является острая задержка мочеиспускания. Оценку кровотока проводили с помощью трансректальной ультразвуковой допплерографии. При это оценивали такие показатели, как максимальная систолическая скорость кровотока, минимальная диастолическая скорость кровотока, индексы резистивности и пульсативности, а также диаметр вен перипростатического венозного сплетения и кровоток в них. Отмечается нарушение кровотока в тканях предстательной железы у больных с острой задержкой мочеиспускания (ОЗМ) на фоне ДГПЖ, которое сопровождается нарушением свертывающей и фибринолитической активности крови

Литолитическая и комбинированная терапия уратного литиаза

The estimation of efficacy of a medication «Trometamol-N» in complex therapy of urate and mixed urolithiasis, with application of extracorporeal shock wave lithotripsy (ESWL), low intensive laser irradiation is done. It was established that after such therapy dissolution of urate and mixed stones has been observed.Проведена оценка эффективности препарата Трометамол-Н в комплексной терапии уратного и смешанного уролитиаза с применением экстрокорпоральной ударноволновой литотрипсии, низкоинтенивного магнитолазерного излучения. Установлено, что на фоне проводимой терапии отмечается растворение уратных и смешанных конкрементов

Polarized interacting exciton gas in quantum wells and bulk semiconductors

We develop a theory to calculate exciton binding energies of both two- and three-dimensional spin polarized exciton gases within a mean field approach. Our method allows the analysis of recent experiments showing the importance of the polarization and intensity of the excitation light on the exciton luminescence of GaAs quantum wells. We study the breaking of the spin degeneracy observed at high exciton density $(5 \ \ 10^{10} cm ^2)$. Energy level splitting betwen spin +1 and spin -1 is shown to be due to many-body inter-excitonic exchange while the spin relaxation time is controlled by intra-exciton exchange.Comment: Revtex, 4 figures sent by fax upon request by e-mai

Natural equilibrium states for multimodal maps

This paper is devoted to the study of the thermodynamic formalism for a class of real multimodal maps. This class contains, but it is larger than, Collet-Eckmann. For a map in this class, we prove existence and uniqueness of equilibrium states for the geometric potentials $-t \log|Df|$, for the largest possible interval of parameters $t$. We also study the regularity and convexity properties of the pressure function, completely characterising the first order phase transitions. Results concerning the existence of absolutely continuous invariant measures with respect to the Lebesgue measure are also obtained

The spectrum features of UHECRs below and surrounding GZK

The energy spectrum of UHECRs is discussed on the basis of the Yakutsk array database analysis. In the region E=0.1 to 30 EeV the showers are detected under trigger-500, while at energies above 30 EeV the whole acceptance area for trigger-1000 is used in order to utilize all the data available in the region of GZK cutoff.Comment: Invited talk at CRIS2004: GZK and surroundings, Catania, Italy, 31.05.04. To appear in Nucl. Phys. B Proc. Supp

Nitric oxide induces the distinct invisibility phenotype of Mycobacterium tuberculosis

During infection Mycobacterium tuberculosis (Mtb) forms physiologically distinct subpopulations that are recalcitrant to treatment and undetectable using standard diagnostics. These difficult to culture or differentially culturable (DC) Mtb are revealed in liquid media, their revival is often stimulated by resuscitation-promoting factors (Rpf) and prevented by Rpf inhibitors. Here, we investigated the role of nitric oxide (NO) in promoting the DC phenotype. Rpf-dependent DC Mtb were detected following infection of interferon-γ-induced macrophages capable of producing NO, but not when inducible NO synthase was inactivated. After exposure of Mtb to a new donor for sustained NO release (named NOD), the majority of viable cells were Rpf-dependent and undetectable on solid media. Gene expression analyses revealed a broad transcriptional response to NOD, including down-regulation of all five rpf genes. The DC phenotype was partially reverted by over-expression of Rpfs which promoted peptidoglycan remodelling. Thus, NO plays a central role in the generation of Rpf-dependent Mtb, with implications for improving tuberculosis diagnostics and treatments

The Atmospheric Chemistry Suite (ACS) of Three Spectrometers for the ExoMars 2016 Trace Gas Orbiter

The Atmospheric Chemistry Suite (ACS) package is an element of the Russian contribution to the ESA-Roscosmos ExoMars 2016 Trace Gas Orbiter (TGO) mission. ACS consists of three separate infrared spectrometers, sharing common mechanical, electrical, and thermal interfaces. This ensemble of spectrometers has been designed and developed in response to the Trace Gas Orbiter mission objectives that specifically address the requirement of high sensitivity instruments to enable the unambiguous detection of trace gases of potential geophysical or biological interest. For this reason, ACS embarks a set of instruments achieving simultaneously very high accuracy (ppt level), very high resolving power (>10,000) and large spectral coverage (0.7 to 17 μm—the visible to thermal infrared range). The near-infrared (NIR) channel is a versatile spectrometer covering the 0.7–1.6 μm spectral range with a resolving power of ∼20,000. NIR employs the combination of an echelle grating with an AOTF (Acousto-Optical Tunable Filter) as diffraction order selector. This channel will be mainly operated in solar occultation and nadir, and can also perform limb observations. The scientific goals of NIR are the measurements of water vapor, aerosols, and dayside or night side airglows. The mid-infrared (MIR) channel is a cross-dispersion echelle instrument dedicated to solar occultation measurements in the 2.2–4.4 μm range. MIR achieves a resolving power of >50,000. It has been designed to accomplish the most sensitive measurements ever of the trace gases present in the Martian atmosphere. The thermal-infrared channel (TIRVIM) is a 2-inch double pendulum Fourier-transform spectrometer encompassing the spectral range of 1.7–17 μm with apodized resolution varying from 0.2 to 1.3 cm−1. TIRVIM is primarily dedicated to profiling temperature from the surface up to ∼60 km and to monitor aerosol abundance in nadir. TIRVIM also has a limb and solar occultation capability. The technical concept of the instrument, its accommodation on the spacecraft, the optical designs as well as some of the calibrations, and the expected performances for its three channels are described