10 research outputs found

    On a graph related to permutability in finite groups

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    This paper has been published in Annali di Matematica Pura ed Applicata. Series IV, 189(4):567-570 (2010). Copyright 2010 by Springer-Verlag. The final publication is available at www.springerlink.com. http://link.springer.com/article/10.1007%2Fs10231-009-0124-7 http://dx.doi.org/10.1007/s10231-009-0124-7For a finite group G we define the graph Γ(G)\Gamma(G) to be the graph whose vertices are the conjugacy classes of cyclic subgroups of G and two conjugacy classes {A,B}\{\mathcal {A}, \mathcal {B}\} are joined by an edge if for some {AA,BBA}\{A \in \mathcal {A},\, B \in \mathcal {B}\, A\} and B permute. We characterise those groups G for which Γ(G)\Gamma(G) is complete.This paper has been suported by the research grants MTM2007-68010-C03-02 from MEC (Spain) and FEDER (European Union) and GV/2007/243 from Generalitat (Valencian Community).http://dx.doi.org/10.1007/s10231-009-0124-7Ballester Bolinches, A.; Cossey, J.; Esteban Romero, R. (2010). On a graph related to permutability in finite groups. Annali di Matematica Pura ed Applicata. 4(189). doi:10.1007/s10231-009-0124-74189Abe S., Iiyori N.: A generalization of prime graphs of finite groups. Hokkaido Math. J. 29(2), 391–407 (2000)Agrawal R.K.: Finite groups whose subnormal subgroups permute with all Sylow subgroups. Proc. Am. Math. Soc. 47(1), 77–83 (1975)Alejandre M.J., Ballester-Bolinches A., Pedraza-Aguilera M.C.: Finite soluble groups with permutable subnormal subgroups. J. Algebra 240(2), 705–722 (2001)Ballester-Bolinches A., Esteban-Romero R.: Sylow permutable subnormal subgroups of finite groups. J. Algebra 251(2), 727–738 (2002)Cooper C.D.H.: Power automorphisms of a group. Math. Z. 107, 335–356 (1968)Herzog M., Longobardi P., Maj M.: On a commuting graph on conjugacy classes of groups. Commun. Algebra 37(10), 3369–3387 (2009)Huppert B.: Endliche Gruppen I, vol. 134 of Grund. Math. Wiss. Springer, Berlin (1967)Longobardi P.: Gruppi finite a fattoriali modulari. Note Math. II, 73–100 (1982)Neumann B.: A problem of Paul Erdős on groups. J. Austral. Math. Soc. Ser. A 21, 467–472 (1976)Ore O.: Contributions to the theory of groups of finite order. Duke Math. J. 5, 431–460 (1939)Schmidt R.: Subgroup lattices of groups. De Gruyter Expositions in Mathematics, vol. 14. Walter de Gruyter, Berlin (1994)Zacher G.: I gruppi risolubli finiti in cui i sottogruppi di composizione coincidono con i sottogrupi quasi-normali. Atti Accad. Naz. Lincei Rend. cl. Sci. Fis. Mat. Natur. 37(8), 150–154 (1964

    Evaluación de los costes de mantenimiento y restauración de edificios patrimoniales

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    En las últimas décadas, no se han adoptado protocolos de mantenimiento adecuados para la conservación y rehabilitación del patrimonio cultural. En España, el mantenimiento de estos edificios tiene, comúnmente, una naturaleza reactiva, estando condicionada por criterios subjetivos y por la existencia de fondos disponibles para la realización de las acciones de rehabilitación. Por tanto, es fundamental que los gestores del patrimonio construido tengan información relevante que ayude a tomar decisiones sobre la prioridad de intervención y las acciones preventivas a realizar en edificios patrimoniales. Existen cada vez más estudios relacionados con la definición de estrategias de mantenimiento adecuadas, que permitan mejorar el estado de conservación del patrimonio construido, con especial foco en la optimización de costos de mantenimiento empleados durante el ciclo de vida de estos edificios. Este trabajo identifica los factores que condicionan la decisión de intervenir en un conjunto de edificios patrimoniales, localizados en el sur de España. Se analizan las acciones de mantenimiento realizadas en un conjunto de 20 iglesias parroquiales y sus costes durante un período de 11 años (entre 2005 y 2015). En este estudio se evalúa la eficacia de las acciones realizadas, identificando los puntos fuertes y débiles de las intervenciones y estrategias adoptadas a lo largo del período de tiempo analizado. Los resultados obtenidos demuestran que las acciones de naturaleza reactiva deben ser minimizadas, para reducir los costes de mantenimiento. El conocimiento adquirido con las estrategias adoptadas en el pasado permite proporcionar información relevante para la planificación adecuada de futuras estrategias de mantenimient

    SARS-CoV-2 viral load in nasopharyngeal swabs is not an independent predictor of unfavorable outcome

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    The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at first patient’s hospital evaluation to predict unfavorable outcomes. We conducted a prospective cohort study including 321 adult patients with confirmed COVID-19 through RT-PCR in nasopharyngeal swabs. Quantitative Synthetic SARS-CoV-2 RNA cycle threshold values were used to calculate the viral load in log10 copies/mL. Disease severity at the end of follow up was categorized into mild, moderate, and severe. Primary endpoint was a composite of intensive care unit (ICU) admission and/or death (n = 85, 26.4%). Univariable and multivariable logistic regression analyses were performed. Nasopharyngeal SARS-CoV-2 viral load over the second quartile (≥ 7.35 log10 copies/mL, p = 0.003) and second tertile (≥ 8.27 log10 copies/mL, p = 0.01) were associated to unfavorable outcome in the unadjusted logistic regression analysis. However, in the final multivariable analysis, viral load was not independently associated with an unfavorable outcome. Five predictors were independently associated with increased odds of ICU admission and/or death: age ≥ 70 years, SpO2, neutrophils > 7.5 × 103/µL, lactate dehydrogenase ≥ 300 U/L, and C-reactive protein ≥ 100 mg/L. In summary, nasopharyngeal SARS-CoV-2 viral load on admission is generally high in patients with COVID-19, regardless of illness severity, but it cannot be used as an independent predictor of unfavorable clinical outcome

    Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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    Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have the capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is a deficit in DC numbers and IFN-α production, which has been associated with disease severity. In this work, we described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers. Remarkably, previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+ myeloid DCs and pDCs seven months after SARS-CoV-2 infection. Moreover, the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed. These findings contribute to a better understanding of the immunological sequelae of COVID-19

    On some permutable products of supersoluble groups

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    It is well known that a group G = AB which is the product of two supersoluble subgroups A and B is not supersoluble in general. Under suitable permutability conditions on A and B, we show that for any minimal normal subgroup N both AN and BN are supersoluble. We then exploit this to establish some sufficient conditions for G to be supersoluble

    Antifungal and antitumor activities of a monoclonal antibody directed against a stress mannoprotein of Candida albicans

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    Immunization of mice with a stress mannoprotein of >200 kDa from the cell wall of Candida albicans led to the production of monoclonal antibody (Mab) C7. The immunogen is a major target of secretory IgA and its expression is regulated by different environmental conditions including temperature, pH, glucose concentration and ammonium sulphate in the culture medium. Mab C7 reacted with a peptide epitope present in the >200 kDa antigen as well as in a number of antigens from the blastoconidium and germ tube cell wall, including enolase. In addition to its reactivity with C. albicans, Mab C7 also reacted with antigens present in C. krusei, C, tropicalis, C. glabrata, C. dubliniensis and C. lusitaniae, as well as in Cryptococcus neoformans, Scedosporium prolificans and Aspergillus fumigatus. Mab C7 exhibited four important biological activities, namely inhibition of adhesion of C. albicans to a variety of surfaces, inhibition of germination of C. albicans, direct candidacidal activity and direct tumoricidal activity. In tumor cells, Mab C7 reacted with nucleoporin Nup88, a reactivity that can be utilized for diagnostic and prognostic purposes
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