Tecnologías modernas de enseñanza profesional en el sistema de aprendizaje permanente

The professional education system is experiencing an active search for ways and methods to improve the quality of education, which increases the role of imitative teaching methods aimed at developing individual creative skills, forming specialized professional and personal qualities, their ability of adjustment and adaptability to the new economic conditions. Teaching methods as forms of interaction between teacher and students are intended to acquire skills, as well as to educate and develop a personality. The teacher’s task consists of the rational use of such teaching methods that ensure the best achievement of the objective, which is the training of qualified specialists. The diversity of these methods should increase students’ interest in learning and cognitive activity. This study concludes on the benefits of a professional school where, priority should be given to active teaching methods aimed at increasing students’ cognitive activity, developing their personal initiative and potential, forming their creative approach and allowing them to solve important learning tasks. and organization.El sistema de educación profesional está experimentando una búsqueda activa de formas y métodos para mejorar la calidad de la educación, lo que aumenta el papel de los métodos de enseñanza imitativos destinados a desarrollar habilidades creativas individuales, formando las cualidades profesionales y personales especializadas, su capacidad de ajuste y adaptabilidad a las nuevas condiciones económicas. Los métodos de enseñanza como formas de interacción entre el maestro y los estudiantes están destinados a adquirir habilidades, así como a educar y desarrollar la personalidad. La tarea del maestro consiste en el uso racional de tales métodos de enseñanza que aseguren el mejor logro del objetivo, que es la capacitación de especialistas calificados. La diversidad de estos métodos debería aumentar el interés de los estudiantes en el aprendizaje y la actividad cognitiva. Este estudio concluye en los beneficios de una escuela profesional donde, se debe dar prioridad a los métodos de enseñanza activos destinados a aumentar la actividad cognitiva de los estudiantes, desarrollar su iniciativa y potencial personal, formar su enfoque creativo y permitirles resolver importantes tareas de aprendizaje y organización

INVESTIGATION OF THE QUALITY OF SEMI-SMOКED SAUSAGES IN THE HACCP SYSTEM INTEGRATED BY ENTERPRISES ON THE MANUFACTURE OF MEAT AND MEAT PRODUCTION

This article presents the results of scientific research on the production of meat products from beef. Vitamins, amino acids, organoleptic and physico-chemical parameters were investigated. The results of the analysis show that the studied parameters in all samples did not exceed the maximum permissible concentrations established by the requirements of the sanitary rules and norms. Thus, the introduction of the HACCP system into production is one of the ways to achieve high quality

Space-Time Description of Scalar Particle Creation by a Homogeneous Isotropic Gravitational Field

We give the generalization of the method of the space-time description of particle creation by a gravitational field for a scalar field with nonconformal coupling to the curvature. The space-time correlation function is obtained for a created pair of the quasi-particles, corresponding to a diagonal form of the instantaneous Hamiltonian. The case of an adiabatic change of the metric of homogeneous isotropic space is analyzed. We show that the created pairs of quasi-particles in de Sitter space should be interpreted as pairs of virtual particles.Comment: 7 pages, 3 figure

Experience with the triple fixed combination in patients with chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is one of the most important problems of modern medicine associated with a high mortality rate, high costs of treatment and relief of exacerbations of COPD. The main objectives of COPD treatment are symptom control, reduce the frequency of exacerbations and hospitalizations, and reduced risk of exacerbation in the future. The recommendations of the GOLD initiative propose a treatment approach based on the assessment of exacerbation rates external respiratory function indicators (spirometric classification of GOLD), the severity of symptoms assessed on the CAT test and mMRC. When choosing therapy, the physician must first of all take into account the effectiveness, safety of the drug, adherence to treatment in order to achieve the therapeutic goals of treating patients with COPD. The change in therapeutic approaches in COPD treatment is associated with the accumulation of knowledge in physiology, clinical pharmacology, and the isolation of new clinical phenotypes of COPD. Currently, the main classes of drugs for the treatment of COPD are long-acting beta-agonists (LABA), longacting anticholinergics (LAMA), and inhaled glucocorticosteroids (ICS). The evolution of therapeutic approaches in COPD treatment has led to the creation of new fixed inhalation combinations of the main groups of drugs for COPD treatment. The therapeutic strategies recommended by GOLD and the Russian Federal Guidelines determine the long-term goals of COPD treatment – the impact on the risk of exacerbations in the future. The presented clinical observation of a patient with severe COPD demonstrates the effectiveness of a triple fixed combination vilanterol/umeclidinium/fluticasone furoate 55/22/92 μg as a basic therapy. The  chosen treatment strategy not only reduces the  severity of  the  symptoms of  the  disease, but also reduces the  risk of exacerbations in the future

The comparison of 2D and 3D speckle-tracking echocardiography values in young athletes

Objective: to analyze the parameters of 2D and 3D transthoracic echocardiography (TEE) with speckle-tracking technology in young athletes. Materials and methods: 79 athletes (52 male, 27 female, median age 20,5±3,7 years) undergone prospective analysis. Participants were divided into groups by level of training (group A-professionals and group B-amateurs) and by gender (group 1-men and group 2-women). Athletes underwent 12-lead ECG, 2D TTE and 3D TTE with a speckle-tracking. The evaluation of LV function was performed using the speckle-tracking method with the assessment of LV longitudinal strain in the Automated Function Imaging mode. Results: significant differences in LDV (

Forming A Pedagogue’s Research Competences in Innovative Educational Environment

Changes that take place in different spheres of life in Russia (economic, political, social, cultural) determine new requirements to the goals, values, functions of education in providing the development and self-realization of students. A graduate of a modern school should master a complex of information and research skills, and have critical and creative thinking. Research methodology. The orientation of education towards the growth of a student as a person, bearer of certain individual peculiarities, and activity subject may be of use only if an effective strategy of pedagogic work is developed. Such a strategy should be scientifically grounded on the basic principles of modern approaches implemented in pedagogy and psychology: humanistic, personality-, activity- and competence-oriented. Research results. Four spheres of a pedagogue’s professional activity in an innovative educational environment have been distinguished: sphere of analysis, synthesis and mastering pioneering pedagogic experience; sphere of popularization and initial practical use of pioneering pedagogic experience and advanced developments; sphere of the improvement of professional skills and realization of creative potential of a teacher; sphere of innovative processes in the system of education. Discussion. The essence of a pedagogue’s research activity is conditioned by the functions, which are based on the following factors: optimization of the teaching and educational process; specifically, structured controlled cognitive process; processes of self-improvement, self-instruction and selfeducation, self-realization; mastering professional pedagogic activity of a new level. Conclusion. Four levels of the development of a teacher’s research competences have been distinguished: basic, empiric (local and initiative), productive (tactical), and constructive (strategic)

A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type

[EN] All variables affecting the morphology of mesoporous silica nanoparticles (MSN) should be carefully analyzed in order to truly tailored design their mesoporous structure according to their final use. Although complete control on MCM-41 synthesis has been already claimed, reproducibility and repeatability of results remain a big issue due to the lack of information reported in literature. Stirring rate, reaction volume, and system configuration (i.e., opened or closed reactor) are three variables that are usually omitted, making the comparison of product characteristics difficult. Specifically, the rate of solvent evaporation is seldom disclosed, and its influence has not been previously analyzed. These variables were systematically studied in this work, and they were proven to have a fundamental impact on final particle morphology. Hence, a high degree of circularity (C = 0.97) and monodispersed particle size distributions were only achieved when a stirring speed of 500 rpm and a reaction scale of 500 mL were used in a partially opened system, for a 2 h reaction at 80 degrees C. Well-shaped spherical mesoporous silica nanoparticles with a diameter of 95 nm, a pore size of 2.8 nm, and a total surface area of 954 m(2) g(-1) were obtained. Final characteristics made this product suitable to be used in biomedicine and nanopharmaceutics, especially for the design of drug delivery systems.This study was funded partially by Departamento Administrativo de Ciencia Tecnología e Innovación–COLCIENCIAS (recipient, Angela A. Beltrán-Osuna); Ministerio de Economía y Competitividad, MINECO, research number MAT2016-76039-C4-1-R (Recipient, José L. Gómez-Ribelles); and Universidad Nacional de Colombia, grant number DIB201010021438 (Recipient, Jairo E. Perilla).Beltrán-Osuna, A.; Gómez Ribelles, JL.; Perilla-Perilla, JE. (2017). 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CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Tandemly repeated DNA families in the mouse genome

<p>Abstract</p> <p>Background</p> <p>Functional and morphological studies of tandem DNA repeats, that combine high portion of most genomes, are mostly limited due to the incomplete characterization of these genome elements. We report here a genome wide analysis of the large tandem repeats (TR) found in the mouse genome assemblies.</p> <p>Results</p> <p>Using a bioinformatics approach, we identified large TR with array size more than 3 kb in two mouse whole genome shotgun (WGS) assemblies. Large TR were classified based on sequence similarity, chromosome position, monomer length, array variability, and GC content; we identified four superfamilies, eight families, and 62 subfamilies - including 60 not previously described. 1) The superfamily of centromeric minor satellite is only found in the unassembled part of the reference genome. 2) The pericentromeric major satellite is the most abundant superfamily and reveals high order repeat structure. 3) Transposable elements related superfamily contains two families. 4) The superfamily of heterogeneous tandem repeats includes four families. One family is found only in the WGS, while two families represent tandem repeats with either single or multi locus location. Despite multi locus location, TRPC-21A-MM is placed into a separated family due to its abundance, strictly pericentromeric location, and resemblance to big human satellites.</p> <p>To confirm our data, we next performed <it>in situ </it>hybridization with three repeats from distinct families. TRPC-21A-MM probe hybridized to chromosomes 3 and 17, multi locus TR-22A-MM probe hybridized to ten chromosomes, and single locus TR-54B-MM probe hybridized with the long loops that emerge from chromosome ends. In addition to <it>in silico </it>predicted several extra-chromosomes were positive for TR by <it>in situ </it>analysis, potentially indicating inaccurate genome assembly of the heterochromatic genome regions.</p> <p>Conclusions</p> <p>Chromosome-specific TR had been predicted for mouse but no reliable cytogenetic probes were available before. We report new analysis that identified <it>in silico </it>and confirmed <it>in situ </it>3/17 chromosome-specific probe TRPC-21-MM. Thus, the new classification had proven to be useful tool for continuation of genome study, while annotated TR can be the valuable source of cytogenetic probes for chromosome recognition.</p