154 research outputs found
In Vivo Early Corneal Biomechanical Changes After Corneal Cross-linking in Patients With Progressive Keratoconus
Comparison of optic disc images from two smartphone-based imaging systems in glaucoma patients and suspects
Labour of Love: An Open Access Manifesto for Freedom, Integrity, and Creativity in the Humanities and Interpretive Social Sciences
We are a group of scholar-publishers based in the humanities and social sciences who are questioning the fairness and scientific tenability of a system of scholarly communication dominated by large commercial publishers. With this Manifesto we wish to repoliticise Open Access to challenge existing rapacious practices in academic publishingânamely, often invisible and unremunerated labour, toxic hierarchies of academic prestige, and a bureaucratic ethos that stifles experimentationâand to bear witness to the indifference they are predicated upon. We mobilise an extended notion of research output, which encompasses the work of building and maintaining the systems, processes, and relations of production that make scholarship possible. We believe that the humanities and social sciences are too often disengaged from the public and material afterlives of their scholarship. We worry that our fields are sleepwalking into a new phase of control and capitalisation, to include continued corporate extraction of value and transparency requirements designed by managers, entrepreneurs, and politicians. We fervently believe that OA can be a powerful tool to advance the ends of civil society and social movements. But opening up the products of our scholarship without questioning how this is done, who stands to profit from it, what model of scholarship is being normalised, and who stands to be silenced by this process may come at a particularly high cost for scholars in the humanities and social sciences
Corneal biomechanics and biomechanically corrected intraocular pressure in primary open-angle glaucoma, ocular hypertension and controls.
AIMS: To compare the biomechanically corrected intraocular pressure (IOP) estimate (bIOP) provided by the Corvis-ST with Goldmann applanation tonometry (GAT-IOP) in patients with high-tension and normal-tension primary open-angle glaucoma (POAG; HTG and NTG), ocular hypertension (OHT) and controls. Moreover, we compared dynamic corneal response parameters (DCRs) of the Corvis-ST in POAG, OHT and controls, evaluated the correlation between global visual field parameters mean deviation and pattern SD (MD and PSD) and DCRs in the POAG group.
METHODS: 156 eyes of 156 patients were included in this prospective, single-centre, observational study, namely 41 HTG and 33 NTG, 45 OHT cases and 37 controls. Central corneal thickness (CCT), GAT-IOP and bIOP were measured, GAT-IOP was also adjusted for CCT (GATAdj). DCRs provided by Corvis-ST were evaluated, MD and PSD were recorded by 24-2 full-threshold visual field. To evaluate the difference in DCRs between OHT, HTG and NTG, a general linear model was used with sex, medications and group as fixed factors and bIOP and age as covariates.
RESULTS: There was a significant difference between GAT-IOP, GATAdj and bIOP in NTG and HTG, OHT and controls. NTG corneas were significantly softer and more deformable compared with controls, OHT and HTG as demonstrated by significantly lower values of stiffness parameters A1 and highest concavity and higher values of inverse concave radius (all p<0.05). There was a significant correlation (p<0.05) between MD, PSD and many DCRs with POAG patients with softer or more compliant corneas more likely to show visual field defects.
CONCLUSIONS: Corneal biomechanics might be a significant confounding factor for IOP measurement that should be considered in clinical decision-making. The abnormality of corneal biomechanics in NTG and the significant correlation with visual field parameters might suggest a new risk factor for the development or progression of NTG
The politicisation of evaluation: constructing and contesting EU policy performance
Although systematic policy evaluation has been conducted for decades and has been growing strongly within the European Union (EU) institutions and in the member states, it remains largely underexplored in political science literatures. Extant work in political science and public policy typically focuses on elements such as agenda setting, policy shaping, decision making, or implementation rather than evaluation. Although individual pieces of research on evaluation in the EU have started to emerge, most often regarding policy âeffectivenessâ (one criterion among many in evaluation), a more structured approach is currently missing. This special issue aims to address this gap in political science by focusing on four key focal points: evaluation institutions (including rules and cultures), evaluation actors and interests (including competencies, power, roles and tasks), evaluation design (including research methods and theories, and their impact on policy design and legislation), and finally, evaluation purpose and use (including the relationships between discourse and scientific evidence, political attitudes and strategic use). The special issue considers how each of these elements contributes to an evolving governance system in the EU, where evaluation is playing an increasingly important role in decision making
Gendered vulnerabilities to climate change: insights from the semi-arid regions of Africa and Asia
Emerging and on-going research indicates that vulnerabilities to impacts of climate change are gendered. Still, policy approaches aimed at strengthening local communitiesâ adaptive capacity largely fail to recognize the gendered nature of everyday realities and experiences. This paper interrogates some of the emerging evidence in selected semi-arid countries of Africa and Asia from a gender perspective, using water scarcity as an illustrative example. It emphasizes the importance of moving beyond the counting of numbers of men and women to unpacking relations of power, of inclusion and exclusion in decision-making, and challenging cultural beliefs that have denied equal opportunities and rights to differently positioned people, especially those at the bottom of economic and social hierarchies. Such an approach would make policy and practice more relevant to peopleâs differentiated needs and responses
The recent intellectual structure of geography
An active learning project in an introductory graduate course used multidimensional scaling of the name index in Geography in America at the Dawn of the 21st Century, by Gary Gaile and Cort Willmott, to reveal some features of the discipline\u27s recent intellectual structure relevant to the relationship between human and physical geography. Previous analyses, dating to the 1980s, used citation indices or Association of American Geographers spe- cialty-group rosters to conclude that either the regional or the methods and environmental subdisciplines bridge human and physical geography. The name index has advantages over those databases, and its analysis reveals that the minimal connectivity that occurs between human and physical geography has recently operated more through environmental than through either methods or regional subdisciplines
Un atto dâamore: Manifesto Open Access per la libertĂ , lâintegritĂ e la creativitĂ nelle scienze umane e nelle scienze sociali interpretative
Labour of Love: An Open Access Manifesto for Freedom, Integrity, and Creativity in the Humanities and Interpretive Social Sciences, is the result of an LSE Research Infrastructure and Investmentâfunded workshop entitled Academic Freedom, Academic Integrity and Open Access in the Social Sciences, organised by Andrea E. Pia and held at the London School of Economics on September 9, 2019.Un atto dâamore: Manifesto Open Access per la libertĂ , lâintegritĂ e la creativitĂ nelle scienze umane e nelle scienze sociali interpretative, Ăš il risultato di un workshop finanziato da LSE Research Infrastructure and Investment Funds dal titolo Academic Freedom, Academic Integrity and Open Access in the Social Sciences, organizzato da Andrea E. Pia e tenuto presso la London School of Economics il 9 settembre 2019
Un acto de amor. Un Manifiesto de Acceso Abierto por la libertad, la integridad y la creatividad en las humanidades y las ciencias sociales interpretativas
Labour of Love. An Open Access Manifesto for Freedom, Integrity, and Creativity in the Humanities and Interpretive Social Sciences, is the result of an LSE Research Infrastructure and Investmentâfunded workshop entitled Academic Freedom, Academic Integrity and Open Access in the Social Sciences, organised by Andrea E. Pia and held at the London School of Economics on September 9, 2019.Un acto de amor. Un Manifiesto de Acceso Abierto por la Libertad, la Integridad y la Creatividad en las Humanidades y las Ciencias Sociales Interpretativas, es el resultado de un taller financiado por la Infraestructura de InvestigaciĂłn y la InversiĂłn de la LSE, titulado Academic Freedom, Academic Integrity and Open Access in the Social Sciences, organizado por Andrea E. Pia y celebrado en la London School of Economics el 9 de septiembre de 2019
Researcher selfâcare and caring in the research community
This paper seeks to begin a discussion on researcher selfâcare in response to the state of contemporary academia, which sees increasing issues of academic stress and anxiety, and the growing use of facile metrics. Specifically, we wish to explore the potential a critical engagement with selfâcare poses for ourselves as academics and the communities of which we are a part â what kinpaisby (2008) refers to as the âcommuniversity.â Our central argument is that selfâcare may be regarded as a radical act that can push against the interests of the neoliberal university. We illustrate how researcher selfâcare can be engaged as a reflexive process that operates to create and inform change within our communities through recognising ourselves as networked actors, rather than selfâcontained individuals as the neoliberal ideology would have us believe. This paper is intended as an opening towards a much larger discussion regarding academia â of the communities, work environments, and âimpactsâ we wish to be a part of and how to begin working towards realising these
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