TRANSDERMIC TRANSPORT BY PORTABLE DEVICES: ANOTHER WAY TO APPLY COSMETICS

ABSTRACT: The skin is an important route of drug application. The outermost layer of skin, the stratum cornea is the first protective portion that hinders the permeability of substances. Physical methods such as ultrasonic peeling, ionization and electroporation can facilitate the entry of substance in the skin. The aim of the study was observe the ultrasonic peeling, the ionization and electroporation effects associated with Nano Gold fluid and Anti-winkle Serum in the skin. METHODS: Six Wistar animals were used and divided randomly into 3 groups of 2 animals each (a control group, a treated group with ultrasonic peeling plus Nano Gold fluid and another group treated with Dermoroller plus Anti-wrinkle Serum). The treatment lasted 10 days consecutive. RESULTS: The Histological analyzes showed a reduced in the cornea stratum and an increase of the epidermis in the group treated with ultrasonic peeling plus ionization and Nano Gold fluid. CONCLUSION: Furthermore, it was observed an increase in the fibroblasts with neoformation of collagen in the treated group with the Dermaroller plus serum anti-wrinkle

Factors Associated with Excess Weight in a Sample Population of School Adolescents

Introduction: Overweight has been reported as a public health problem. Consequently, this suggests epidemiological studies for nutritional surveillance.Objective:  To analyze the prevalence and factors associated with overweight among high school students in Capital of the Brazilian Western Amazon.Methods: cross-sectional study of 2694 adolescents from public and private schools. They collected demographic, socioeconomic and sedentary behavior through self-responded questionnaire. Overweight rating followed the recommendations of the World Health Organization (2007). The prevalence rates were calculated, odds ratio and their confidence intervals were calculated at 95%. They identified the factors associated with excess weight by multiple binary logistic regression.Results: The overall prevalence of overweight was 24.2% and 26.3% for males and 22.4% for females. After adjustment factors associated with overweight were economic class A / B (OR = 1.30, 95% CI 1.02 to 1.45), private school type (OR = 1.21, 95% CI 1,02-1.46) and poor health perception (OR = 1.27, 95% CI 1.03 to 1.58). It was concluded that excess weight showed high prevalence in economy class adolescents and B and private schools in Porto Velho, RO, Brazil.Conclusion: Therefore, the practice of physical activity associated with a diet should be encouraged, in addition to reducing sedentary behavior, to prevent the development of overweight and obesity

COBERTURA VACINAL NO MUNICÍPIO DE SOBRAL-CEARÁ NO PERÍODO DE 2010 A 2014

O Programa Nacional de Imunização (PNI) do Ministério da Saúde foi criado a fim de disponibilizar vacinas gratuitamente para a população, prevenindo doenças no âmbito da atenção primária a saúde. Esse programa tornou o Brasil um dos principais atuantes no combate a patologias infectocontagiosas. O presente trabalho tem por objetivo demonstrar dados sobre a cobertura vacinal na cidade de Sobral nos anos de 2010 a 2014

ERICA: prevalência de dislipidemia em adolescentes brasileiros

OBJETIVO Determinar a distribuição de colesterol total, LDL-colesterol, HDL-colesterol e triglicerídeos em adolescentes brasileiros, bem como a prevalência de níveis alterados de tais parâmetros. MÉTODOS Foram utilizados dados do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA), estudo transversal, de âmbito nacional e base escolar que avaliou adolescentes de 12 a 17 anos, residentes em municípios com mais de 100 mil habitantes. Foi avaliada a média e distribuição dos níveis plasmáticos de colesterol total, LDL-colesterol, HDL-colesterol e triglicerídeos. Dislipidemia foi determinada por níveis de colesterol total ≥ 170 mg/dl, LDL-colesterol ≥ 130 mg/dl, HDL-colesterol < 45 mg/dL ou triglicerídeos ≥ 130 mg/dl. Os dados foram analisados por sexo, idade e regiões do Brasil. RESULTADOS Foram avaliados 38.069 adolescentes, 59,9% do sexo feminino; 54,2% com idade entre 15 a 17 anos. Os valores médios encontrados foram: colesterol total 148,1 mg/dl (IC95% 147,1-149,1), HDL-colesterol 47,3 mg/dl (IC95% 46,7-47,9), LDL-colesterol 85,3 mg/dl (IC95% 84,5-86,1), e triglicerídeos 77,8 mg/dl (IC95% 76,5-79,2). Adolescentes do sexo feminino apresentaram níveis médios de colesterol total, LDL-colesterol e HDL-colesterol mais elevados, mas sem diferença nos níveis de triglicerídeos. Não houve diferença significativa de valores médios entre adolescentes de 12 a 14 e de 15 a 17 anos. As alterações com maior prevalência foram HDL-colesterol baixo (46,8% [IC95% 44,8-48,9]), hipercolesterolemia (20,1% [IC95% 19,0-21,3]) e hipertrigliceridemia (7,8% [IC95% 7,1-8,6]). O LDL-colesterol elevado foi observado em 3,5% (IC95% 3,2-4,0) dos adolescentes. As prevalências de HDL-colesterol baixo foram mais elevadas nas regiões Norte e Nordeste do País. CONCLUSÕES Uma parcela significativa dos adolescentes brasileiros apresenta alterações dos lípides plasmáticos. A alta prevalência de HDL-colesterol baixo e a hipertrigliceridemia, sobretudo nas regiões Norte e Nordeste do Brasil, devem ser analisadas em futuros estudos para subsidiar formulações de estratégias de intervenções eficazes.OBJECTIVE To determine the distribution of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides in Brazilian adolescents, as well as the prevalence of altered levels of such parameters. METHODS Data from the Study of Cardiovascular Risks in Adolescents (ERICA) were used. This is a country-wide, school-based cross-sectional study that evaluated 12 to 17-year old adolescents living in cities with over 100,000 inhabitants. The average and distribution of plasma levels of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides were evaluated. Dyslipidemia was determined by levels of total cholesterol ≥ 170 mg/dl, LDL cholesterol ≥ 130 mg/dl, HDL cholesterol < 45 mg/dL, or triglycerides ≥ 130 mg/dl. The data were analyzed by gender, age, and regions in Brazil. RESULTS We evaluated 38,069 adolescents – 59.9% of females, and 54.2% between 15 and 17 years. The average values found were: total cholesterol = 148.1 mg/dl (95%CI 147.1-149.1), HDL cholesterol = 47.3 mg/dl (95%CI 46.7-47.9), LDL cholesterol = 85.3 mg/dl (95%CI 84.5-86.1), and triglycerides = 77.8 mg/dl (95%CI 76.5-79.2). The female adolescents had higher average levels of total cholesterol, LDL cholesterol, and HDL cholesterol, without differences in the levels of triglycerides. We did not observe any significant differences between the average values among 12 to 14 and 15- to 17-year old adolescents. The most prevalent lipid alterations were low HDL cholesterol (46.8% [95%CI 44.8-48.9]), hypercholesterolemia (20.1% [95%CI 19.0-21.3]), and hypertriglyceridemia (7.8% [95%CI 7.1-8.6]). High LDL cholesterol was found in 3.5% (95%CI 3.2-4.0) of the adolescents. Prevalence of low HDL cholesterol was higher in Brazil’s North and Northeast regions. CONCLUSIONS A significant proportion of Brazilian adolescents has alterations in their plasma lipids. The high prevalence of low HDL cholesterol and hypertriglyceridemia, especially in Brazil’s North and Northeast regions, must be analyzed in future studies, to support the creation of strategies for efficient interventions

Eficiência e resposta à aplicação de nitrogênio de genótipos de feijão comum cultivados em várzea tropical do Estado do Tocantins

The common bean is a crop with big socioeconomic interest in many countries, being a crop with high nutrient demand, mainly nitrogen which is uptaken in big amounts. Thus, it is necessary the adoption of cultivars which are efficient and responsive to nitrogen use. So, this study was carried out in order to evaluate the nitrogen use efficiency and response of common bean genotypes grown in irrigated lowland soil at State of Tocantins. The study was carried out in two trials (high and low nitrogen level) in a completely randomized blocks design, being evaluated 25 genotypes in three replications. To simulate environments with low and high N level, doses of 0 and 120 kg ha-1&nbsp;of N were utilized respectively. The genotypes were sorted about nitrogen use efficiency though their grain yield. There is difference about nitrogen use efficiency and response to nitrogen application among the evaluated genotypes.O feijão comum é uma cultura com grande interesse socioeconômico em muitos países, sendo uma cultura com alta demanda de nutrientes, principalmente nitrogênio, que é consumido em grandes quantidades. Assim, é necessária a adoção de cultivares eficientes e responsivas ao uso de nitrogênio. Assim, este estudo foi realizado com o objetivo de avaliar a eficiência do uso de nitrogênio e a resposta de genótipos de feijoeiro cultivados em solo irrigado de várzea do Estado do Tocantins. O estudo foi realizado em dois ensaios (alto e baixo nível de nitrogênio), em delineamento de blocos completamente casualizados, sendo avaliados 25 genótipos em três repetições. Para simular ambientes com baixo e alto nível de N, foram utilizadas doses de 0 e 120 kg ha-1 de N, respectivamente. Os genótipos foram classificados quanto à eficiência no uso de nitrogênio, apesar do rendimento de grãos. Há diferença quanto à eficiência no uso de nitrogênio e resposta à aplicação de nitrogênio entre os genótipos avaliados. &nbsp

On the semi-analytical Chhajlany and Malnev method for aproximate non-perturbative solutions of the Schrödinger equation with even polynomial potential

We propose, as part of the introductory study of Quantum Mechanics at undergraduate level, to employ the Chhajlany and Malnev method (MCM) for obtaining approximate semi-analytical solutions of the unidimensional Schrödinger equation (energy eigenvalues and eigenfunctions), as an alternative to perturbative methods (which bring issues of convergence of infinite series), to methods like WKB (of semi-classical character, and not completely quantum), and to methods such as the finite difference method (purely numerical), for the study of polynomial potentials with even powers. Polynomial potentials appear, for instance, as effective potentials in the study of oscillations about local minima of a given potential. In the present work, we develop in detail the MCM for the harmonic and quartic anharmonic quantum oscillators, using a Fortran code that implements that method, for those cases. Pre-requisites for understanding the MCM are the familiarity with Schrödinger equation, as well as with basic tools of integral-differential calculus and linear algebra.Propomos, como parte do estudo introdutório de Mecânica Quântica na graduação, o uso do método de Chhajlany e Malnev (MCM) para obtenção de soluções aproximadas semi-analíticas da equação de Schrödinger unidimensional (autovalores e autofunções de energia), como uma alternativa a métodos perturbativos (que trazem questões de convergência de séries infinitas), a métodos como o WKB (de caráter semi-clássico, e não totalmente quântico), e a métodos como o de diferenças finitas (puramente numéricos), no estudo de potenciais polinomiais de potências pares. Potenciais polinomiais surgem, por exemplo, como potenciais efetivos no estudo de oscilações em torno de mínimos locais de um dado potencial. Neste trabalho, desenvolvemos em detalhe o MCM para o osciladores quânticos harmônico e anarmônico quártico, utilizando um código Fortran que implementa o método, nestes casos. Pré-requisitos para a compreensão do MCM são a familiaridade com a Equação de Schrödinger, bem como ferramentas básicas do cálculo íntegro-diferencial e álgebra linear

A UESB como apoio ao enfrentamento da pandemia Covid-19: o caso da produção de antisséptico - Campus Itapetinga-BA

Neste artigo, abordamos o processo de produção de álcool antisséptico 70% líquido pela Universidade Estadual do Sudoeste da Bahia (UESB), Campus Itapetinga, como forma de contribuir para o enfrentamento da Covid-19. Trata-se de um relato de experiência quanto à produção e distribuição de sanitizantes. Tais procedimentos seguiram as etapas de estudos dos protocolos da OMS e da ANVISA para produção do álcool 70% em situação de combate à pandemia, e foram adaptados e desenvolvidos pelo Laboratório de Tecnologia de Produtos de Origem Vegetal (LTPOV). A estrutura da UESB e a expertise da equipe para a produção do álcool mostraram a capacidade desse ambiente universitário para se adaptar e cumprir com sua responsabilidade social em torno do enfrentamento de diferentes situações, nesse caso, a pandemia Covid-19.In this article, we discuss the production process of antiseptic alcohol 70% liquid by the State University of Southwest Bahia (UESB), Campus Itapetinga, as a way to contribute to the confrontation of Covid-19. This is an experience report regarding the production and distribution of sanitizers. Such procedures followed the stages of studies of the protocols of WHO and ANVISA for the production of 70% alcohol in a situation of combat to the pandemic, and were adapted and developed by the Laboratory of Technology of Products of Vegetable Origin (LTPOV). The structure of UESB and the expertise of the team for the production of alcohol showed the capacity of this university environment to adapt and comply with its social responsibility around coping with different situations, in this case the pandemic Covid-19

ERICA: prevalence of dyslipidemia in Brazilian adolescents

ABSTRACT OBJECTIVE: To determine the distribution of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides in Brazilian adolescents, as well as the prevalence of altered levels of such parameters. METHODS: Data from the Study of Cardiovascular Risks in Adolescents (ERICA) were used. This is a country-wide, school-based cross-sectional study that evaluated 12 to 17-year old adolescents living in cities with over 100,000 inhabitants. The average and distribution of plasma levels of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides were evaluated. Dyslipidemia was determined by levels of total cholesterol ≥ 170 mg/dl, LDL cholesterol ≥ 130 mg/dl, HDL cholesterol &lt; 45 mg/dL, or triglycerides ≥ 130 mg/dl. The data were analyzed by gender, age, and regions in Brazil. RESULTS: We evaluated 38,069 adolescents -59.9% of females, and 54.2% between 15 and 17 years. The average values found were: total cholesterol = 148.1 mg/dl (95%CI 147.1-149.1), HDL cholesterol = 47.3 mg/dl (95%CI 46.7-47.9), LDL cholesterol = 85.3 mg/dl (95%CI 84.5-86.1), and triglycerides = 77.8 mg/dl (95%CI 76.5-79.2). The female adolescents had higher average levels of total cholesterol, LDL cholesterol, and HDL cholesterol, without differences in the levels of triglycerides. We did not observe any significant differences between the average values among 12 to 14 and 15-to 17-year old adolescents. The most prevalent lipid alterations were low HDL cholesterol (46.8% .9]), hypercholesterolemia .3]), and hypertriglyceridemia ). High LDL cholesterol was found in 3.5% (95%CI 3.2-4.0) of the adolescents. Prevalence of low HDL cholesterol was higher in Brazil&apos;s North and Northeast regions. CONCLUSIONS: A significant proportion of Brazilian adolescents has alterations in their plasma lipids. The high prevalence of low HDL cholesterol and hypertriglyceridemia, especially in Brazil&apos;s North and Northeast regions, must be analyzed in future studies, to support the creation of strategies for efficient interventions

Erratum to: The study of cardiovascular risk in adolescents – ERICA: rationale, design and sample characteristics of a national survey examining cardiovascular risk factor profile in Brazilian adolescents

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