6 research outputs found
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
- Author
- Aarsland Dag
- Abdelnour C.
- Abdelnour Carla
- Adarmes-Gomez A.D.
- Alarcon-Martin Emilio
- Alcolea Daniel
- Alegret Montserrat
- Alvarez Ignacio
- Alvarez Victoria
- Amouyel Philippe
- Andrade Victor
- Andreassen Ole A.
- Antonell Anna
- Antunez Carmen
- Appollonio Ildebrando
- Arcaro Marina
- Archetti Silvana
- Arias Pastor Alfonso
- Armstrong Nicola J.
- Arosio Beatrice
- Bailly Henri
- Banaj Nerisa
- Baquero Miquel
- Belen Pastor Ana
- Bellenguez Celine
- Benaque Alba
- Benussi Alberto
- Benussi Luisa
- Bernal Sanchez-Arjona Maria
- Bessi Valentina
- Binetti Giuliano
- Bis Joshua C.
- Blennow Kaj
- Blesa Rafael
- Boada Merce
- Boerwinkle Eric
- Borroni Barbara
- Boschi Silvia
- Bossu Paola
- Buerger Katharina
- Buiza-Rueda Dolores
- Bullido Maria J.
- Caffarra Paolo
- Calero Miguel
- Carolina Dalmasso Maria
- Carracedo Angel
- Cecchetti Roberta
- Cervera-Carles Laura
- Charbonnier Camille
- Chene Genevieve
- Chillotti Caterina
- Ciccone Simona
- Clarimon Jordi
- Clark Christopher
- Conti Elisa
- Corbaton-Anchuelo Arturo
- Corma-Gomez Anais
- Dardiotis Efthimios
- de Mendonca Alexandre
- de Rojas Itziar
- Deckert Juergen
- Deckert Jurgen
- del Ser Teodoro
- Deniz-Naranjo M. Candida
- Deramecourt Vincent
- DeStefano Anita L.
- Dichgans Martin
- Diehl-Schmid Janine
- Diez-Fairen Monica
- Djurovic Srdjan
- Duezel Emrah
- Dufouil Carole
- Duron Emmanuelle
- Duzel Emrah
- Engelborghs Sebastiaan
- Escott-Price Valentina
- Esiri Margaret
- Espinosa Ana
- Ewers Michael
- Farotti Lucia
- Farrer Lindsay A.
- Fenoglio Chiara
- Fernandez-Fuertes Marta
- Ferreira Catarina B.
- Ferri Evelyn
- Fischer Peter
- Fliessbach Klaus
- Fornage Myriam
- Fortea Juan
- Fostinelli Silvia
- Franco-Macias Emilio
- Frank-Garcia Ana
- Frikke-Schmidt Ruth
- Froelich Lutz
- Galimberti Daniela
- Garcia-Gonzalez Pablo
- Garcia-Madrona Sebastian
- Garcia-Ribas Guillermo
- Gelpi Ellen
- Ghidoni Roberta
- Giaccone Giorgio
- Giedraitis Vilmantas
- Giegling Ina
- Gil Silvia
- Goldhardt Oliver
- Gonzalez-Perez Antonio
- Graff Caroline
- Grande Giulia
- Grenier-Boley Benjamin
- Grimmer Timo
- Gruenblatt Edna
- Grunblatt Edna
- Haapasalo Annakaisa
- Hadjigeorgiou Georgios
- Haegg Sara
- Hagg Sara
- Haines Jonathan L.
- Hampel Harald
- Hanon Oliver
- Hartmann Annette M.
- Hausner Lucrezia
- Heilmann-Heimbach Stefanie
- Helisalmi Seppo
- Heneka Michael T.
- Hernandez Isabel
- Herrmann Martin J.
- Hiltunen Mikko
- Hoffmann Per
- Holmans Peter A.
- Holmes Clive
- Holstege Henne
- Hort Jakub
- Huerto Vilas Raquel
- Huisman Martijn
- Hulsman Marc
- Ikram M. Arfan
- Ingelsson Martin
- Jansen Iris E.
- Jessen Frank
- Jian Xueqiu
- K\ufc\ue7\ufckali Fahri
- Kalaria Rajesh N.
- Karlsson Ida K.
- Kehoe Patrick Gavin
- Kern Silke
- Kilander Lena
- Kivipelto Miia
- Kleineidam Luca
- Kok Almar A.L.
- Kornhuber Johannes
- Kosmidis Mary H.
- Kunkle Brian W.
- Kuulasmaa Teemu
- Lage Carmen
- Lambert Jean-Charles
- Lebouvier Thibaud
- Lehtisalo Jenni
- Lemstra Afina W.
- Lerch Ondrej
- Lleo Alberto
- Loewenmark Malin
- Lopez de Munain Adolfo
- Lowenmark Malin
- Macias Juan
- Macleod C.
- Maier Wolfgang
- Mangialasche Francesca
- Maria Garcia-Alberca Jose
- Marquie Marta
- Marshall Rachel
- Martin Montes Angel
- Martinez Rodriguez Carmen
- Masullo Carlo
- Mather Karen A.
- Mayeux Richard
- Mead Simon
- Medina Miguel
- Meggy Alun
- Mendoza Silvia
- Menendez-Gonzalez Manuel
- Mir Pablo
- Molina-Porcel Laura
- Montrreal Laura
- Moreno Fermin
- Moreno-Grau Sonia
- Morgan Kevin
- Munoz-Fernandez Carmen
- Nacmias Benedetta
- Naj Adam C.
- Ngandu Tiia
- Nicolas Gael
- Noethen Markus M.
- Nordestgaard Borge G.
- Nothen Markus M.
- Orellana Adelina
- Ortega Gemma
- Padovani Alessandro
- Papenberg Goran
- Parnetti Lucilla
- Pasquier Florence
- Pastor Pau
- Pedersen Nancy L.
- Perez-Cordon Alba
- Perez-Tur Jordi
- Pericak-Vance Margaret A.
- Peters Oliver
- Pijnenburg Yolande A. L.
- Pineda Juan A.
- Pinol-Ripoll Gerard
- Pisanu Claudia
- Polak Thomas
- Popp Julius
- Posthuma Danielle
- Quenez Olivier
- Quintela Ines
- Rabano Alberto
- Rainero Innocenzo
- Ramirez Alfredo
- Real Luis M.
- Reynolds Chandra A.
- Riedel-Heller Steffi
- Riederer Peter
- Roberto Natalia
- Rodriguez-Rodriguez Eloy
- Rongve Arvid
- Rosas Allende Irene
- Rosende-Roca Maitee
- Rossi Giacomina
- Rossi Paolo Dionigi
- Royo Jose Luis
- Rubino Elisa
- Ruiz Agustin
- Rujescu Dan
- Saez Maria Eugenia
- Sakka Paraskevi
- Saltvedt Ingvild
- Sanabria Angela
- Sanchez-Garcia Florentino
- Sanchez-Juan Pascual
- Sanchez-Valle Raquel
- Sando Sigrid Botne
- Satizabal Claudia L.
- Scamosci Michela
- Scarmeas Nikolaos
- Scarpini Elio
- Schellenberg Gerard D.
- Scheltens Philip
- Scherbaum Norbert
- Scherer Martin
- Schmid Matthias
- Schneider Anja
- Seidu Nazib M.
- Selbaek Geir
- Seripa Davide
- Serrano-Rios Manuel
- Seshadri Sudha
- Sims Rebecca
- Skoog Ingmar
- Skrobot Olivia Anna
- Sleegers Kristel
- Smith A. David
- Soininen Hilkka
- Sorbi Sandro
- Sotolongo-Grau Oscar
- Spallazzi Marco
- Spalletta Gianfranco
- Spottke Annika
- Squassina Alessio
- Stahlbom Anne Kinhult
- Stringa Najada
- Tagliavini Fabrizio
- Tankard Rick M.
- Tarraga Lluis
- Teresa Martinez-Larrad Maria
- Tesi Niccolo
- Thomassen Jesper Qvist
- Tremolizzo Lucio
- Tsolaki Magda
- Tybjaerg-Hansen Anne
- Tybjorg-Hansen Anne
- Ullgren Abbe
- Valero Sergi
- Van Broeckhoven Christine
- van der Flier Wiesje M.
- van der Lee Sven J.
- Van Dongen Jasper
- van Duijn Cornelia M.
- van Schoor Natasja M.
- Vandenberghe Rik
- Vidal Jean-Sebastien
- Vogelgsang Jonathan
- Vyhnalek Martin
- Wagner Michael
- Wallon David
- Wang Li-San
- Weinhold Leonie
- Williams Julie
- Wiltfang Jens
- Yang Qiong
- Yannakoulia Mary
- Zetterberg Henrik
- Zettergren Anna
- Zulaica Miren
- Publication venue
- Nat Commun
- Publication date
- 01/01/2021
- Field of study
Funder: Funder: Fundación bancaria ‘La Caixa’ Number: LCF/PR/PR16/51110003 Funder: Grifols SA Number: LCF/PR/PR16/51110003 Funder: European Union/EFPIA Innovative Medicines Initiative Joint Number: 115975 Funder: JPco-fuND FP-829-029 Number: 733051061Genetic discoveries of Alzheimer's disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer's disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer's disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer's disease
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
- Author
- Aarsland D.
- Abdelnour C.
- Abdelnour C.
- Adarmes-Gomez A. D.
- Aguilera N.
- Alarcon E.
- Alarcon-Martin E.
- Alarcon-Martin E.
- Alcolea D.
- Alegret M.
- Alegret M.
- Alonso M. D.
- Alvarez I.
- Alvarez I.
- Alvarez V.
- Alvarez V.
- Amer-Ferrer G.
- Amouyel P.
- Anastasiou A.
- Anastasiou C.
- Andrade V.
- Andreassen O. A.
- Andreoni S.
- Antequera M.
- Antikainen R.
- Antonell A.
- Antunez C.
- Antunez C.
- Appollonio I.
- Arcaro M.
- Archetti S.
- Arias Pastor A.
- Armstrong N. J.
- Arosio B.
- Assogna F.
- Bacha J. I.
- Bagnoli S.
- Bailly H.
- Banaj N.
- Baquero M.
- Baquero M.
- Bastiani P.
- Belezhanska D.
- Bellenguez C.
- Bellou E.
- Benaque A.
- Benaque A.
- Bennett K.
- Benussi A.
- Benussi L.
- Bernal M.
- Bernal Sanchez-Arjona M.
- Besse C.
- Bessi V.
- Binetti G.
- Bis J. C.
- Bizzarro A.
- Bjerke M.
- Blennow K.
- Blesa R.
- Blesa R.
- Boada M.
- Boada M.
- Boada M.
- Boecker H.
- Boerwinkle E.
- Boland A.
- Borroni B.
- Boschi S.
- Bossu P.
- Botne Sando S.
- Brayne C.
- Bresner C.
- Brusco L. I.
- Buendia M.
- Buerger K.
- Buiza-Rueda D.
- Buiza-Rueda D.
- Bullido M. J.
- Bullido M. J.
- Burguera J. A.
- Burholt V.
- Caffarra P.
- Calero M.
- Calero M.
- Canabate P.
- Carracedo A.
- Carracedo A.
- Carrillo F.
- Carrion-Claro M.
- Casajeros M. J.
- Castano E. M.
- Cecchetti R.
- Cervera-Carles L.
- Charbonnier C.
- Chene G.
- Chillotti C.
- Chipi E.
- Ciccone S.
- Ciullo V.
- Clare L.
- Clarimon J.
- Clarimon J.
- Clark C.
- Conti E.
- Corbaton-Anchuelo A.
- Corbaton-Anchuelo A.
- Cores V.
- Corma-Gomez A.
- Costantini E.
- Craig D.
- Cruz-Gamero J. M.
- Cuesta C.
- Custodero C.
- Daian D.
- Dalmasso M. C.
- Daniele A. (ORCID:0000-0003-1641-5852)
- Dardiotis E.
- de Mendonca A.
- de Pancorbo M. M.
- De Roeck E.
- de Rojas I.
- Deckert J.
- del Ser T.
- del Ser T.
- Del Zompo M.
- Deleuze J. -F.
- Deniz-Naranjo M. C.
- Deramecourt V.
- DeStefano A. L.
- Dichgans M.
- Diego S.
- Diehl-Schmid J.
- Diez-Fairen M.
- Diez-Fairen M.
- Dionigi Rossi P.
- Djurovic S.
- Dufouil C.
- Duron E.
- Duzel E.
- Engelborghs S.
- Escott-Price V.
- Escuela R.
- Esiri M.
- Espinosa A.
- Espinosa A.
- Etchepareborda I.
- Ewers M.
- Farotti L.
- Farrer L. A.
- Fenoglio C.
- Fernandez-Fuertes M.
- Ferrarese C.
- Ferrari C.
- Ferreira C. B.
- Ferri E.
- Fin B.
- Fischer P.
- Fliessbach K.
- Fornage M.
- Fortea J.
- Fortea J.
- Fostinelli S.
- Fox N. C.
- Franco-Macias E.
- Franco-Macias E.
- Frank-Garcia A.
- Frank-Garcia A.
- Frikke-Schmidt R.
- Froelich L.
- Gailhajenet A.
- Galeano P.
- Galimberti D.
- Garcia Madrona S.
- Garcia-Alberca J. M.
- Garcia-Alberca J. M.
- Garcia-Gonzalez P.
- Garcia-Madrona S.
- Garcia-Ribas G.
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- Garrote-Espina L.
- Gelpi E.
- Germani S.
- Ghidoni R.
- Giaccone G.
- Giedraitis V.
- Giegling I.
- Gil S.
- Gil S.
- Goldhardt O.
- Gomez-Garre P.
- Gonzalez-Perez A.
- Graff C.
- Grande G.
- Greco A.
- Grenier-Boley B.
- Grimmer T.
- Grozeva D.
- Grunblatt E.
- Guitart M.
- Haapasalo A.
- Hadjigeorgiou G.
- Hagg S.
- Haines J. L.
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- Harris J.
- Hartmann A. M.
- Harwood J.
- Hausner L.
- Heilmann-Heimbach S.
- Helisalmi S.
- Heneka M. T.
- Hernandez I.
- Hernandez I.
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- Herrman M. J.
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- Heun R.
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- Hoffmann P.
- Holmans P. A.
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- Hooper N. M.
- Hort J.
- Huerto Vilas R.
- Huisman M.
- Hulsman M.
- Ibarria M.
- Ikram M. A.
- Ingelsson M.
- Ingino C.
- Janowitz D.
- Jansen I. E.
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- Jessen F.
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- Kalaria R. N.
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- Kochen S.
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- Koivisto A.
- Kok A. A. L.
- Kolsch H.
- Kornhuber J.
- Kosmidis M. H.
- Kosmidis M. H.
- Koutsouraki E.
- Kucukali F.
- Kunkle B. W.
- Kuulasmaa T.
- Laatikainen T.
- Labrador Espinosa M. A.
- Lacidogna G.
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- Lage C.
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- Lambert J. -C.
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- Legaz A.
- Lehtisalo J.
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- Leonenko G.
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- Lisetti V.
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- Lleo A.
- Lleo A.
- Lopez de Munain A.
- Lopez de Munain A.
- Lopez-Garcia S.
- Lopez-Garcia S.
- Love S.
- Lowenmark M.
- Luckuck L.
- Macias J.
- Macias J.
- Macias-Garcia D.
- Macleod C.
- Maier W.
- Mangialasche F.
- Mangone C.
- Mann D. M.
- Manzanares S.
- Marianthi A.
- Marin M.
- Marin T.
- Marin-Munoz J.
- Maronas O.
- Marquie M.
- Marquie M.
- Marquie M.
- Marshall R.
- Martin E.
- Martin Montes A.
- Martin Montes A.
- Martinez B.
- Martinez C.
- Martinez C.
- Martinez M. T.
- Martinez Rodriguez C.
- Martinez V.
- Martinez-Lage Alvarez P.
- Martinez-Larrad M. T.
- Masullo C.
- Mather K. A.
- Matoska V.
- Matthews F.
- Mauleon A.
- Mayeux R.
- McCracken C.
- McGuinness B.
- Mead S.
- Mecocci P.
- Medel N.
- Medina M.
- Medina M.
- Meggy A.
- Mehrabian S.
- Mendioroz Iriarte M.
- Mendoza S.
- Menendez-Gonzalez M.
- Menzies G.
- Mihova K. Y.
- Mir P.
- Mir P.
- Molina-Porcel L.
- Molinuevo J. L.
- Montrreal L.
- Montrreal L.
- Morelli L.
- Moreno F.
- Moreno M.
- Moreno-Grau S.
- Moreno-Grau S.
- Morgan K.
- Muchnik C.
- Munoz-Fernandez C.
- Nacmias B.
- Naj A. C.
- Natunen T.
- Neary D.
- Ngandu T.
- Nicolas G.
- Nordestgaard B. G.
- Nothen M. M.
- Novack G.
- Olaso R.
- Olivar N.
- Orellana A.
- Orellana A.
- Orsini M.
- Ortega G.
- Ortega G.
- Ortiz C.
- Padovani A.
- Palacio D. L.
- Pancho A.
- Papenberg G.
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- Pasquier F.
- Passmore P.
- Pastor A. B.
- Pastor P.
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- Pedersen N. L.
- Peleja E.
- Peltonen M.
- Perez Tur J.
- Perez-Cordon A.
- Perez-Cordon A.
- Perez-Tur J.
- Pericak-Vance M. A.
- Perinan-Tocino T.
- Perneczky R.
- Peters O.
- Phillips J.
- Piaceri I.
- Pickering-Brown S.
- Pijnenburg Y. A. L.
- Pineda J. A.
- Pineda J. A.
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- Piras F.
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- Polak T.
- Politis D. G.
- Polvikoski T. M.
- Popp J.
- Posthuma D.
- Preckler S.
- Prestia F. A.
- Priller J.
- Quenez O.
- Quintela I.
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- Rabano A.
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- Rainer M.
- Rainero I.
- Ramirez A.
- Real de Asua D.
- Real L. M.
- Real L. M.
- Reyes Toso C.
- Reynolds C. A.
- Richardson A.
- Riedel-Heller S.
- Riederer P.
- Rios M.
- Roberto N.
- Rodrigo S.
- Rodriguez-Rodriguez E.
- Rodriguez-Rodriguez E.
- Rojo M.
- Rongve A.
- Rongve A.
- Rosas Allende I.
- Rosende-Roca M.
- Rosende-Roca M.
- Rossi G.
- Roveta F.
- Royo J. L.
- Royo J. L.
- Rubino E.
- Ruiz A.
- Ruiz A.
- Ruiz A.
- Rujescu D.
- Saad S.
- Saenz A.
- Saez M. E.
- Saez M. E.
- Sakka P.
- Sala G.
- Salani F.
- Saltvedt I.
- Salvadori N.
- Sanabria A.
- Sanabria A.
- Sanchez Abalos M.
- Sanchez del Valle Diaz R.
- Sanchez-Garcia F.
- Sanchez-Juan P.
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- Sanchez-Valle R.
- Sastre I.
- Satizabal C. L.
- Scamosci M.
- Scarmeas N.
- Scarpini E.
- Schellenberg G. D.
- Scheltens P.
- Scherbaum N.
- Scherer M.
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- Schneider A.
- Schott J. M.
- Seidu N. M.
- Selbaek G.
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- Serrano-Rios M.
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- Seshadri S.
- Sevillano Z.
- Sims R.
- Skoog I.
- Skrobot O. A.
- Sleegers K.
- Smith A. D.
- Snowden J.
- Soininen H.
- Solfrizzi V.
- Solis P.
- Solomon A.
- Sommerville E. W.
- Sorbi S.
- Sotolongo-Grau O.
- Sotolongo-Grau O.
- Spallazzi M.
- Spalletta G.
- Spottke A.
- Squassina A.
- Strandberg T.
- Stringa N.
- Tagliavini F.
- Takalo M.
- Tankard R. M.
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- Tegos T.
- Teipel S.
- Tesi N.
- Thomassen J. Q.
- Thonberg H.
- Todd S.
- Traykov L.
- Tremolizzo L.
- Tsolaki M.
- Tuomilehto J.
- Tybjaerg-Hansen A.
- Ullgren A.
- Vacca A.
- Valero S.
- Valero S.
- Valero S.
- Van Broeckhoven C.
- van der Flier W. M.
- van der Lee S. J.
- Van Dongen J.
- van Duijn C. M.
- van Schoor N. M.
- Vandenberghe R.
- Vardy E. R. L. C.
- Vargas L.
- Vicente M. P.
- Vidal J. -S.
- Vigo-Ortega R.
- Vivancos L.
- Vogelgsang J.
- Vyhnalek M.
- Wagner M.
- Wallon D.
- Wang L. -S.
- Weber H.
- Weinhold L.
- Wilcock G.
- Williams J.
- Wiltfang J.
- Windle G.
- Woods R.
- Yang Q.
- Yannakoulia M.
- Zetterberg H.
- Zettergren A.
- Zoia C. P.
- Zulaica M.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer’s disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer’s disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer’s disease
Erratum: Author Correction: Common variants in Alzheimer\u27s disease and risk stratification by polygenic risk scores (Nature communications (2021) 12 1 (3417))
- Author
- Aarsland D
- Abdelnour C
- Alarcon-Martin E
- Alcolea D
- Alegret M
- Alvarez I
- Alvarez V
- Amouyel P
- Andrade V
- Andreassen OA
- Antonell A
- Antunez C
- Appollonio I
- Arcaro M
- Archetti S
- Arias Pastor A
- Armstrong NJ
- Arosio B
- Bailly H
- Banaj N
- Baquero M
- Bellenguez C
- Benaque A
- Benussi A
- Benussi L
- Bernal Sanchez-Arjona M
- Bessi V
- Binetti G
- Bis JC
- Blennow K
- Blesa R
- Boada M
- Boerwinkle E
- Borroni B
- Boschi S
- Bossu P
- Botne Sando S
- Buerger K
- Buiza-Rueda D
- Bullido MJ
- Caffarra P
- Calero M
- Carracedo A
- Cecchetti R
- Cervera-Carles L
- Charbonnier C
- Chene G
- Chillotti C
- Ciccone S
- Clarimon J
- Clark C
- Conti E
- Corbaton-Anchuelo A
- Corma-Gomez A
- Dalmasso MC
- Dardiotis E
- de Mendonca A
- de Rojas I
- Deckert J
- Del Ser T
- Deniz-Naranjo MC
- Deramecourt V
- DeStefano AL
- Dichgans M
- Diehl-Schmid J
- Diez-Fairen M
- Dionigi Rossi P
- Djurovic S
- Dufouil C
- Duron E
- Duzel E
- Engelborghs S
- Escott-Price V
- Esiri M
- Espinosa A
- Ewers M
- Farotti L
- Farrer LA
- Fenoglio C
- Fernandez-Fuertes M
- Ferreira CB
- Ferri E
- Fischer P
- Fliessbach K
- Fornage M
- Fortea J
- Fostinelli S
- Franco-Macias E
- Frank-Garcia A
- Frikke-Schmidt R
- Froelich L
- Galimberti D
- Garcia-Alberca JM
- Garcia-Gonzalez P
- Garcia-Madrona S
- Garcia-Ribas G
- Gelpi E
- Ghidoni R
- Giaccone G
- Giedraitis V
- Giegling I
- Gil S
- Goldhardt O
- Gonzalez-Perez A
- Graff C
- Grande G
- Grenier-Boley B
- Grimmer T
- Grunblatt E
- Haapasalo A
- Hadjigeorgiou G
- Hagg S
- Haines JL
- Hampel H
- Hanon O
- Hartmann AM
- Hausner L
- Heilmann-Heimbach S
- Helisalmi S
- Heneka MT
- Hernandez I
- Herrmann MJ
- Hiltunen M
- Hoffmann P
- Holmans PA
- Holmes C
- Holstege H
- Hort J
- Huerto Vilas R
- Huisman M
- Hulsman M
- Ikram MA
- Ingelsson M
- Jansen IE
- Jessen F
- Jian X
- Kalaria RN
- Karlsson IK
- Kehoe PG
- Kern S
- Kilander L
- Kinhult Stahlbom A
- Kivipelto M
- Kleineidam L
- Kok AAL
- Kornhuber J
- Kosmidis MH
- Kucukali F
- Kunkle BW
- Kuulasmaa T
- Lage C
- Lambert J-C
- Lebouvier T
- Lehtisalo J
- Lemstra AW
- Lerch O
- Lleo A
- Lopez de Munain A
- Lowenmark M
- Macias J
- Maier W
- Mangialasche F
- Marquie M
- Marshall R
- Martin Montes A
- Martinez Rodriguez C
- Martinez-Larrad MT
- Masullo C
- Mather KA
- Mayeux R
- Mead S
- Mecocci P
- Medina M
- Meggy A
- Mendoza S
- Menendez-Gonzalez M
- Mir P
- Molina-Porcel L
- Montrreal L
- Moreno F
- Moreno-Grau S
- Morgan K
- Munoz-Fernandez C
- Nacmias B
- Naj AC
- Ngandu T
- Nicolas G
- Nordestgaard BG
- Nothen MM
- Orellana A
- Ortega G
- Padovani A
- Papenberg G
- Parnetti L
- Pasquier F
- Pastor AB
- Pastor P
- Pedersen NL
- Perez-Cordon A
- Perez-Tur J
- Pericak-Vance MA
- Peters O
- Pijnenburg YAL
- Pineda JA
- Pinol-Ripoll G
- Pisanu C
- Polak T
- Popp J
- Posthuma D
- Quenez O
- Quintela I
- Rabano A
- Rainero I
- Ramirez A
- Real LM
- Reynolds CA
- Riedel-Heller S
- Riederer P
- Roberto N
- Rodriguez-Rodriguez E
- Rongve A
- Rosas Allende I
- Rosende-Roca M
- Rossi G
- Royo JL
- Rubino E
- Ruiz A
- Rujescu D
- Saez ME
- Sakka P
- Saltvedt I
- Sanabria A
- Sanchez-Garcia F
- Sanchez-Juan P
- Sanchez-Valle R
- Satizabal CL
- Scamosci M
- Scarmeas N
- Scarpini E
- Schellenberg GD
- Scheltens P
- Scherbaum N
- Scherer M
- Schmid M
- Schneider A
- Seidu NM
- Selbaek G
- Seripa D
- Serrano-Rios M
- Seshadri S
- Sims R
- Skoog I
- Skrobot OA
- Sleegers K
- Soininen H
- Sorbi S
- Sotolongo-Grau O
- Spallazzi M
- Spalletta G
- Spottke A
- Squassina A
- Stringa N
- Tagliavini F
- Tankard RM
- Tarraga L
- Tesi N
- Thomassen JQ
- Tremolizzo L
- Tsolaki M
- Tybjaerg-Hansen A
- Ullgren A
- Valero S
- Van Broeckhoven C
- van der Flier WM
- van der Lee SJ
- Van Dongen J
- van Duijn CM
- van Schoor NM
- Vandenberghe R
- Vidal J-S
- Vogelgsang J
- Vyhnalek M
- Wagner M
- Wallon D
- Wang L-S
- Weinhold L
- Williams J
- Wiltfang J
- Yang Q
- Yannakoulia M
- Zetterberg H
- Zettergren A
- Zulaica M
- Publication venue
- NLM (Medline)
- Publication date
- Field of study
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
- Author
- Aarsland Dag
- Abdelnour C.
- Abdelnour Carla
- Adarmes-Gomez A.D.
- Alarcon-Martin Emilio
- Alcolea Daniel
- Alegret Montserrat
- Alvarez Ignacio
- Alvarez Victoria
- Amouyel Philippe
- Andrade Victor
- Andreassen Ole A.
- Antonell Anna
- Antunez Carmen
- Appollonio Ildebrando
- Arcaro Marina
- Archetti Silvana
- Arias Pastor Alfonso
- Armstrong Nicola J.
- Arosio Beatrice
- Bailly Henri
- Banaj Nerisa
- Baquero Miquel
- Belen Pastor Ana
- Bellenguez Celine
- Benaque Alba
- Benussi Alberto
- Benussi Luisa
- Bernal Sanchez-Arjona Maria
- Bessi Valentina
- Binetti Giuliano
- Bis Joshua C.
- Blennow Kaj
- Blesa Rafael
- Boada Merce
- Boerwinkle Eric
- Borroni Barbara
- Boschi Silvia
- Bossu Paola
- Buerger Katharina
- Buiza-Rueda Dolores
- Bullido Maria J.
- Caffarra Paolo
- Calero Miguel
- Carolina Dalmasso Maria
- Carracedo Angel
- Cecchetti Roberta
- Cervera-Carles Laura
- Charbonnier Camille
- Chene Genevieve
- Chillotti Caterina
- Ciccone Simona
- Clarimon Jordi
- Clark Christopher
- Conti Elisa
- Corbaton-Anchuelo Arturo
- Corma-Gomez Anais
- Dardiotis Efthimios
- de Mendonca Alexandre
- de Rojas Itziar
- Deckert Juergen
- Deckert Jurgen
- del Ser Teodoro
- Deniz-Naranjo M. Candida
- Deramecourt Vincent
- DeStefano Anita L.
- Dichgans Martin
- Diehl-Schmid Janine
- Diez-Fairen Monica
- Djurovic Srdjan
- Duezel Emrah
- Dufouil Carole
- Duron Emmanuelle
- Duzel Emrah
- Engelborghs Sebastiaan
- Escott-Price Valentina
- Esiri Margaret
- Espinosa Ana
- Ewers Michael
- Farotti Lucia
- Farrer Lindsay A.
- Fenoglio Chiara
- Fernandez-Fuertes Marta
- Ferreira Catarina B.
- Ferri Evelyn
- Fischer Peter
- Fliessbach Klaus
- Fornage Myriam
- Fortea Juan
- Fostinelli Silvia
- Franco-Macias Emilio
- Frank-Garcia Ana
- Frikke-Schmidt Ruth
- Froelich Lutz
- Galimberti Daniela
- Garcia-Gonzalez Pablo
- Garcia-Madrona Sebastian
- Garcia-Ribas Guillermo
- Gelpi Ellen
- Ghidoni Roberta
- Giaccone Giorgio
- Giedraitis Vilmantas
- Giegling Ina
- Gil Silvia
- Goldhardt Oliver
- Gonzalez-Perez Antonio
- Graff Caroline
- Grande Giulia
- Grenier-Boley Benjamin
- Grimmer Timo
- Gruenblatt Edna
- Grunblatt Edna
- Haapasalo Annakaisa
- Hadjigeorgiou Georgios
- Haegg Sara
- Hagg Sara
- Haines Jonathan L.
- Hampel Harald
- Hanon Oliver
- Hartmann Annette M.
- Hausner Lucrezia
- Heilmann-Heimbach Stefanie
- Helisalmi Seppo
- Heneka Michael T.
- Hernandez Isabel
- Herrmann Martin J.
- Hiltunen Mikko
- Hoffmann Per
- Holmans Peter A.
- Holmes Clive
- Holstege Henne
- Hort Jakub
- Huerto Vilas Raquel
- Huisman Martijn
- Hulsman Marc
- Ikram M. Arfan
- Ingelsson Martin
- Jansen Iris E.
- Jessen Frank
- Jian Xueqiu
- K\ufc\ue7\ufckali Fahri
- Kalaria Rajesh N.
- Karlsson Ida K.
- Kehoe Patrick Gavin
- Kern Silke
- Kilander Lena
- Kivipelto Miia
- Kleineidam Luca
- Kok Almar A.L.
- Kornhuber Johannes
- Kosmidis Mary H.
- Kunkle Brian W.
- Kuulasmaa Teemu
- Lage Carmen
- Lambert Jean-Charles
- Lebouvier Thibaud
- Lehtisalo Jenni
- Lemstra Afina W.
- Lerch Ondrej
- Lleo Alberto
- Loewenmark Malin
- Lopez de Munain Adolfo
- Lowenmark Malin
- Macias Juan
- Macleod C.
- Maier Wolfgang
- Mangialasche Francesca
- Maria Garcia-Alberca Jose
- Marquie Marta
- Marshall Rachel
- Martin Montes Angel
- Martinez Rodriguez Carmen
- Masullo Carlo
- Mather Karen A.
- Mayeux Richard
- Mead Simon
- Medina Miguel
- Meggy Alun
- Mendoza Silvia
- Menendez-Gonzalez Manuel
- Mir Pablo
- Molina-Porcel Laura
- Montrreal Laura
- Moreno Fermin
- Moreno-Grau Sonia
- Morgan Kevin
- Munoz-Fernandez Carmen
- Nacmias Benedetta
- Naj Adam C.
- Ngandu Tiia
- Nicolas Gael
- Noethen Markus M.
- Nordestgaard Borge G.
- Nothen Markus M.
- Orellana Adelina
- Ortega Gemma
- Padovani Alessandro
- Papenberg Goran
- Parnetti Lucilla
- Pasquier Florence
- Pastor Pau
- Pedersen Nancy L.
- Perez-Cordon Alba
- Perez-Tur Jordi
- Pericak-Vance Margaret A.
- Peters Oliver
- Pijnenburg Yolande A. L.
- Pineda Juan A.
- Pinol-Ripoll Gerard
- Pisanu Claudia
- Polak Thomas
- Popp Julius
- Posthuma Danielle
- Quenez Olivier
- Quintela Ines
- Rabano Alberto
- Rainero Innocenzo
- Ramirez Alfredo
- Real Luis M.
- Reynolds Chandra A.
- Riedel-Heller Steffi
- Riederer Peter
- Roberto Natalia
- Rodriguez-Rodriguez Eloy
- Rongve Arvid
- Rosas Allende Irene
- Rosende-Roca Maitee
- Rossi Giacomina
- Rossi Paolo Dionigi
- Royo Jose Luis
- Rubino Elisa
- Ruiz Agustin
- Rujescu Dan
- Saez Maria Eugenia
- Sakka Paraskevi
- Saltvedt Ingvild
- Sanabria Angela
- Sanchez-Garcia Florentino
- Sanchez-Juan Pascual
- Sanchez-Valle Raquel
- Sando Sigrid Botne
- Satizabal Claudia L.
- Scamosci Michela
- Scarmeas Nikolaos
- Scarpini Elio
- Schellenberg Gerard D.
- Scheltens Philip
- Scherbaum Norbert
- Scherer Martin
- Schmid Matthias
- Schneider Anja
- Seidu Nazib M.
- Selbaek Geir
- Seripa Davide
- Serrano-Rios Manuel
- Seshadri Sudha
- Sims Rebecca
- Skoog Ingmar
- Skrobot Olivia Anna
- Sleegers Kristel
- Smith A. David
- Soininen Hilkka
- Sorbi Sandro
- Sotolongo-Grau Oscar
- Spallazzi Marco
- Spalletta Gianfranco
- Spottke Annika
- Squassina Alessio
- Stahlbom Anne Kinhult
- Stringa Najada
- Tagliavini Fabrizio
- Tankard Rick M.
- Tarraga Lluis
- Teresa Martinez-Larrad Maria
- Tesi Niccolo
- Thomassen Jesper Qvist
- Tremolizzo Lucio
- Tsolaki Magda
- Tybjaerg-Hansen Anne
- Tybjorg-Hansen Anne
- Ullgren Abbe
- Valero Sergi
- Van Broeckhoven Christine
- van der Flier Wiesje M.
- van der Lee Sven J.
- Van Dongen Jasper
- van Duijn Cornelia M.
- van Schoor Natasja M.
- Vandenberghe Rik
- Vidal Jean-Sebastien
- Vogelgsang Jonathan
- Vyhnalek Martin
- Wagner Michael
- Wallon David
- Wang Li-San
- Weinhold Leonie
- Williams Julie
- Wiltfang Jens
- Yang Qiong
- Yannakoulia Mary
- Zetterberg Henrik
- Zettergren Anna
- Zulaica Miren
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
- Author
- Aarsland Dag
- Abdelnour Carla
- Alarcon-Martin Emilio
- Alcolea Daniel
- Alegret Montserrat
- Alvarez Ignacio
- Alvarez Victoria
- Amouyel Philippe
- Andrade Victor
- Andreassen Ole A.
- Antonell Anna
- Antunez Carmen
- Appollonio Ildebrando
- Arcaro Marina
- Archetti Silvana
- Arias Pastor Alfonso
- Armstrong Nicola J.
- Arosio Beatrice
- Bailly Henri
- Banaj Nerisa
- Baquero Miquel
- Belen Pastor Ana
- Bellenguez Celine
- Benaque Alba
- Benussi Alberto
- Benussi Luisa
- Bernal Sanchez-Arjona Maria
- Bessi Valentina
- Binetti Giuliano
- Bis Joshua C.
- Blennow Kaj
- Blesa Rafael
- Boada Merce
- Boerwinkle Eric
- Borroni Barbara
- Boschi Silvia
- Bossu Paola
- Buerger Katharina
- Buiza-Rueda Dolores
- Bullido Maria J.
- Caffarra Paolo
- Calero Miguel
- Carolina Dalmasso Maria
- Cecchetti Roberta
- Cervera-Carles Laura
- Charbonnier Camille
- Chene Genevieve
- Chillotti Caterina
- Ciccone Simona
- Clarimon Jordi
- Clark Christopher
- Conti Elisa
- Corbaton-Anchuelo Arturo
- Corma-Gomez Anais
- Dardiotis Efthimios
- de Mendonca Alexandre
- de Rojas Itziar
- Deckert Jurgen
- del Ser Teodoro
- Deniz-Naranjo M. Candida
- Deramecourt Vincent
- DeStefano Anita L.
- Dichgans Martin
- Diehl-Schmid Janine
- Diez-Fairen Monica
- Djurovic Srdjan
- Dufouil Carole
- Duron Emmanuelle
- Duzel Emrah
- Engelborghs Sebastiaan
- Escott-Price Valentina
- Esiri Margaret
- Espinosa Ana
- Ewers Michael
- Farotti Lucia
- Farrer Lindsay A.
- Fenoglio Chiara
- Fernandez-Fuertes Marta
- Ferreira Catarina B.
- Ferri Evelyn
- Fischer Peter
- Fliessbach Klaus
- Fornage Myriam
- Fortea Juan
- Fostinelli Silvia
- Franco-Macias Emilio
- Frank-Garcia Ana
- Frikke-Schmidt Ruth
- Froelich Lutz
- Galimberti Daniela
- Garcia-Gonzalez Pablo
- Garcia-Madrona Sebastian
- Garcia-Ribas Guillermo
- Gelpi Ellen
- Ghidoni Roberta
- Giaccone Giorgio
- Giedraitis Vilmantas
- Giegling Ina
- Gil Silvia
- Goldhardt Oliver
- Gonzalez-Perez Antonio
- Graff Caroline
- Grande Giulia
- Grenier-Boley Benjamin
- Grimmer Timo
- Grunblatt Edna
- Haapasalo Annakaisa
- Hadjigeorgiou Georgios
- Hagg Sara
- Haines Jonathan L.
- Hampel Harald
- Hanon Oliver
- Hartmann Annette M.
- Hausner Lucrezia
- Heilmann-Heimbach Stefanie
- Helisalmi Seppo
- Heneka Michael T.
- Hernandez Isabel
- Herrmann Martin J.
- Hiltunen Mikko
- Hoffmann Per
- Holmans Peter A.
- Holmes Clive
- Holstege Henne
- Hort Jakub
- Huerto Vilas Raquel
- Huisman Martijn
- Hulsman Marc
- Ikram M. Arfan
- Ingelsson Martin
- Jansen Iris E.
- Jessen Frank
- Jian Xueqiu
- Kalaria Rajesh N.
- Karlsson Ida K.
- Kehoe Patrick Gavin
- Kern Silke
- Kilander Lena
- Kivipelto Miia
- Kleineidam Luca
- Kok Almar A. L.
- Kornhuber Johannes
- Kosmidis Mary H.
- Kucukali Fahri
- Kunkle Brian W.
- Kuulasmaa Teemu
- Lage Carmen
- Lambert Jean-Charles
- Lebouvier Thibaud
- Lehtisalo Jenni
- Lemstra Afina W.
- Lerch Ondrej
- Lleo Alberto
- Lopez de Munain Adolfo
- Lowenmark Malin
- Macias Juan
- Maier Wolfgang
- Mangialasche Francesca
- Maria Garcia-Alberca Jose
- Marquie Marta
- Marshall Rachel
- Martin Montes Angel
- Martinez Rodriguez Carmen
- Masullo Carlo
- Mather Karen A.
- Mayeux Richard
- Mead Simon
- Medina Miguel
- Meggy Alun
- Mendoza Silvia
- Menendez-Gonzalez Manuel
- Mir Pablo
- Molina-Porcel Laura
- Montrreal Laura
- Moreno Fermin
- Moreno-Grau Sonia
- Morgan Kevin
- Munoz-Fernandez Carmen
- Nacmias Benedetta
- Naj Adam C.
- Ngandu Tiia
- Nicolas Gael
- Nordestgaard Borge G.
- Nothen Markus M.
- Orellana Adelina
- Ortega Gemma
- Padovani Alessandro
- Papenberg Goran
- Parnetti Lucilla
- Pasquier Florence
- Pastor Pau
- Pedersen Nancy L.
- Perez-Cordon Alba
- Perez-Tur Jordi
- Pericak-Vance Margaret A.
- Peters Oliver
- Pijnenburg Yolande A. L.
- Pineda Juan A.
- Pinol-Ripoll Gerard
- Pisanu Claudia
- Polak Thomas
- Popp Julius
- Posthuma Danielle
- Quenez Olivier
- Quintela Ines
- Rabano Alberto
- Rainero Innocenzo
- Ramirez Alfredo
- Real Luis M.
- Reynolds Chandra A.
- Riedel-Heller Steffi
- Riederer Peter
- Roberto Natalia
- Rodriguez-Rodriguez Eloy
- Rongve Arvid
- Rosas Allende Irene
- Rosende-Roca Maitee
- Rossi Giacomina
- Rossi Paolo Dionigi
- Royo Jose Luis
- Rubino Elisa
- Ruiz Agustin
- Rujescu Dan
- Saez Maria Eugenia
- Sakka Paraskevi
- Saltvedt Ingvild
- Sanchez-Garcia Florentino
- Sanchez-Juan Pascual
- Sanchez-Valle Raquel
- Sando Sigrid Botne
- Satizabal Claudia L.
- Scamosci Michela
- Scarmeas Nikolaos
- Scarpini Elio
- Schellenberg Gerard D.
- Scheltens Philip
- Scherbaum Norbert
- Scherer Martin
- Schmid Matthias
- Schneider Anja
- Seidu Nazib M.
- Selbaek Geir
- Seripa Davide
- Serrano-Rios Manuel
- Seshadri Sudha
- Sims Rebecca
- Skoog Ingmar
- Skrobot Olivia Anna
- Sleegers Kristel
- Soininen Hilkka
- Sorbi Sandro
- Sotolongo-Grau Oscar
- Spallazzi Marco
- Spalletta Gianfranco
- Spottke Annika
- Squassina Alessio
- Stahlbom Anne Kinhult
- Stringa Najada
- Tagliavini Fabrizio
- Tankard Rick M.
- Tarraga Lluis
- Teresa Martinez-Larrad Maria
- Tesi Niccolo
- Thomassen Jesper Qvist
- Tremolizzo Lucio
- Tsolaki Magda
- Tybjorg-Hansen Anne
- Ullgren Abbe
- Valero Sergi
- Van Broeckhoven Christine
- van der Flier Wiesje M.
- van der Lee Sven J.
- Van Dongen Jasper
- van Duijn Cornelia M.
- van Schoor Natasja M.
- Vandenberghe Rik
- Vidal Jean-Sebastien
- Vogelgsang Jonathan
- Vyhnalek Martin
- Wagner Michael
- Wallon David
- Wang Li-San
- Weinhold Leonie
- Williams Julie
- Wiltfang Jens
- Yang Qiong
- Yannakoulia Mary
- Zetterberg Henrik
- Zettergren Anna
- Zulaica Miren
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study