Psychophysical Research in Development of a Fiber-optic Helmet Mounted Display

The Fiber Optic Helmet Mounted Display (FOHMD) was conceived as an innovative solution to existing flight simulator display deficiencies. An initial (breadboard) version of the system was fabricated to permit experimentation which would help define design requirements for a more refined engineering prototype. A series of visual/human factors studies are being conducted at the USAF Human Resources Laboratory (AFHRL) Operations Training Division, Williams AFB, Arizona to determine the optimum fit of human observer operating characteristics and fiber optic helmet mounted display technology. Pilot performance within a variety of high resolution insert/binocular overlap combinations is being assessed in two classes of environment. The first two of four studies planned incorporate an air-to-air combat environment, whereas the second two studies will use a low level environment with air to ground weapons delivery

Mindfulness based cognitive therapy for young people and their carers: A mixed-methods feasibility study

This is the author accepted manuscript. The final version is available from Springer Verlag via the DOI in this record.We aimed to evaluate whether Mindfulness Based Cognitive Therapy (MBCT) was feasible and acceptable for young people, their parents and the clinicians working with them; whether a parallel course for parents was a useful addition; and whether attendance at MBCT was associated with improved outcomes. The design was a mixed methods service evaluation of an eight session MBCT programme for young people who were recovering from depression. The course was a manualised eight session group intervention. Both young people (n=18) and parents (n=21) completed validated measures before and after the course. Semi-structured interviews were completed with some group participants and clinical staff working in the service. Care records were searched for additional contact following the intervention. Qualitative data from young people, parents and clinicians suggested that MBCT was acceptable and feasible, and provided strategies to cope. The parent course was reported to provide personal support to parents and helped them cope with their child’s depression while also impacting the family, promoted shared understanding of depression and strategies to combat it, and addressed intergenerational aspects of depression. 84% of participants attended at least 6/8 sessions and 48% required no further intervention within the following year. Young people had statistically significant improvements across all outcome measures, while parents had statistically significant improvements in rumination, self-compassion and decentering.Daniel Racey completed this work whilst supported by an NIHR Academic Clinical Fellowship while Kelly Blockley and Vashti Berry are supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South West Peninsula

Who bought the South China Morning Post?

OBJECTIVE: To describe cochleovestibular aspects of superficial hemosiderosis of the central nervous system. BACKGROUND: Superficial hemosiderosis of the central nervous system is a rare disease in which cochleovestibular impairment, cerebellar ataxia, and myelopathy are the most frequent signs. Chronic recurrent subarachnoidal hemorrhage with bleeding into the cerebrospinal fluid is the cause of deposition of hemosiderin in leptomeningeal and subpial tissue, cranial nerves, and spinal cord. Removing the cause of bleeding can prevent irreversible damage to these structures. Because this is the only effective treatment, an early diagnosis is crucial. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center. PATIENT: A 72-year-old woman with superficial hemosiderosis of the central nervous system that developed when she was age 39. METHODS: Neurologic and imaging diagnostic examinations and longitudinal evaluation of cochleovestibular features were performed. Neurosurgery was not performed. RESULTS: Progressive bilateral sensorineural hearing loss and severe vestibular hyporeflexia developed within 15 years, which can be attributed to lesions in the cochleovestibular system. Additional pathology of the central nervous system developed later. CONCLUSION: The patient demonstrated cochlear and vestibular findings that are typical of this pathologic condition. It is the first documented case with extensive serial audiometry used to precisely outline the degree of hearing deterioration during the course of the disease

Short-term memory impairment in vestibular patients can arise independently of psychiatric impairment, fatigue and sleeplessness

Vestibular dysfunction is associated with visual short-term memory impairment, however, it remains unclear if this impairment arises as a direct result of the vestibular dysfunction or is a consequence of comorbid changes in mood, affect, fatigue and/or sleep. To this end, we assessed the concurrence and inter-dependence of these comorbidities in 101 individuals recruited from a tertiary balance clinic with a neuro-otological diagnosis. Over fifty percent of the sample showed reduced visuospatial short-term memory, 60% and 37% exceeded cut-off on the Beck Anxiety and Depression Inventories respectively, 70% exceeded cut-off on the Fatigue Severity Scale, 44% reported daytime sleepiness on the Epworth Sleepiness Scale, and 78% scored above cut-off on the Pittsburg Sleep Quality Index. The high concurrence of these symptoms give reason to infer the existence of a vestibular cognitive affective syndrome. Structural equation modeling indicated that the significant statistical association between general unassisted posture (a marker of chronic vestibular dysfunction and strong predictor of falls risk) and short-term memory was not mediated by mood and wakefulness. Instead, the memory impairment related more directly to vestibular dysfunction. From a rehabilitation perspective, the implication is that if the vestibular disorder is treated successfully then the memory problem will likewise improve

Developing a collaborative agenda for humanities and social scientific research on laboratory animal science and welfare.

Improving laboratory animal science and welfare requires both new scientific research and insights from enquiry in the humanities and social sciences. Whilst scientific research provides evidence to replace, reduce and refine procedures involving laboratory animals (the ‘3Rs’), work in the humanities and social sciences can help understand the social, economic and cultural processes that enhance or impede humane ways of knowing and working with laboratory animals. However, communication across these disciplinary perspectives is currently limited, and they frame questions, generate results, engage users, and seek to influence policy in different ways. To facilitate dialogue and future research at this interface, we convened an interdisciplinary group of 45 life scientists, social scientists, humanities scholars, non-governmental organisations and policy-makers to generate a collaborative research agenda. This drew on other agenda-setting exercises in science policy, using a collaborative and deliberative approach for the identification of research priorities. Participants were recruited from across the community, invited to submit research questions and vote on their priorities. They then met at an interactive workshop in the UK, discussed all 136 questions submitted, and collectively defined the 30 most important issues for the group. The output is a collaborative future agenda for research in the humanities and social sciences on laboratory animal science and welfare. The questions indicate a demand for new research in the humanities and social sciences to inform emerging discussions and priorities on the governance and practice of laboratory animal research, including around: international harmonisation, openness and public engagement, ‘cultures of care’, harm-benefit analysis and the future of the 3Rs. The process underlines the value of interdisciplinary exchange for improving mutual understanding of different research cultures and identifies ways of enhancing the effectiveness of future research at the interface between the humanities, social sciences, science and science policy

Job search information behaviours: An ego-net study of networking amongst young job-seekers

Networking is considered an integral feature of job search, yet its behavioural manifestation has received little attention in the extant literature. Here this is addressed in a study of young job-seekers that adopted an egocentric network approach underpinned by Information Behaviour theory, with specific reference to Wilson's model of information needs and seeking. The analysis of data from semi-structured interviews reveals that job-seekers acquire a broad range of job search information from contacts in their networks, and that the contributions of such contacts extend beyond the sharing of job vacancy alerts. In addition, in cases where social media platforms are accessed by job-seekers, these facilitate crucial ties to industry contacts, and provide valuable informational opportunities to those who adopt them. These findings contribute to a widened understanding of the information behaviours that support the effective mobilisation of contacts within social networks during job search, and are of particula

New constraints on the age and conditions of LPHT metamorphism in the southwestern Central Zone of the Damara Belt, Namibia and implications for tectonic setting

Orthopyroxene-bearing pelitic migmatites and associated anatectic leucogranites from the southwestern Central Zone of the Damara Belt provide revised constraints on the age and grade of LPHT metamorphism and its timing relative to deformation. Pseudosection modelling using THERMOCALC 3.33 indicates a single metamorphic event with peak temperatures of ca. 835 °C and pressures of 4.9 kbar for a garnet–cordierite–biotite–orthopyroxene schist. These temperatures confirm the attainment of true granulite facies conditions in the belt and are higher than previous estimates based on cation-exchange thermobarometry, which are likely to have been affected by retrograde re-equilibration and underestimate peak temperatures for the Central Zone by 50–150 °C. The early growth of sillimanite, consumption of sillimanite to produce cordierite, and the late development of garnet, together with modal isopleths and textural constraints on mineral reactions suggest a near-isobaric heating path for the southwestern Central Zone. Field and petrographic relationships indicate that the metamorphic peak was coeval with non-coaxial D2 deformation that produced orogen-normal, south- to SE-verging, km-scale, recumbent folds and late-D2 shear zones linked to NE–SW, orogen-parallel, extension. Weighted mean U–Pb singlegrain concordia ages of 520.3 ± 4.6 Ma (zircon) and 514.1 ± 3.1 Ma (monazite) from a syn-D2 anatectic garnet-bearing granite constrain the age of metamorphism and the D2 deformation event in the southwestern Central Zone to 520–510 Ma. It is suggested that two tectonometamorphic episodes are preserved in the Central Zone. NW-verging folding and thrusting coeval with the emplacement of the Salem-type granites and maficdioritic Goas Suite took place at 550–530 Ma, and south- to SE-verging folding, shearing and NE–SW extension at 520–510Ma was coeval with granulite-facies metamorphism and the emplacement of crustal melt granitoids. These events are temporally distinct and should not be considered different rheological responses to a single tectonic episode. We suggest that the 550–530Ma event records crustal thickening related to collision of the Congo and Kalahari cratons,whilst the 520–510 Maevent reflects orogenic collapse and crustal thinning,with a possible heat contribution as the result of detachment of the subcontinental lithosphere following collision, resulting in addition of heat to the lower crust.Luke Longridge was partially supported during this research by scholarships from the National Research Foundation (NRF) in South Africa, and additional research funding was provided by the Geological Society of South Africa's (GSSA) Research, Education and Investment (REI) Fund, and by the Jim and Gladys Taylor Education Trust. All of these contributions are gratefully acknowledged