21 research outputs found
Improving Security for SCADA Sensor Networks with Reputation Systems and Self-Organizing Maps
The reliable operation of modern infrastructures depends on computerized systems and Supervisory Control and Data Acquisition (SCADA) systems, which are also based on the data obtained from sensor networks. The inherent limitations of the sensor devices make them extremely vulnerable to cyberwarfare/cyberterrorism attacks. In this paper, we propose a reputation system enhanced with distributed agents, based on unsupervised learning algorithms (self-organizing maps), in order to achieve fault tolerance and enhanced resistance to previously unknown attacks. This approach has been extensively simulated and compared with previous proposals
Age-related pharmacodynamics in a bumblebee-microsporidian system mirror similar patterns in vertebrates
Immune systems provide a key defence against diseases. However, they are not a panacea and so both vertebrates and invertebrates co-opt naturally occurring bioactive compounds to treat themselves against parasites and pathogens. In vertebrates this co-option is complex, with pharmacodynamics leading to differential effects of treatment at different life stages, which may reflect age-linked differences in the immune system. However, our understanding of pharmacodynamics in invertebrates is almost non-existent. Critically, this knowledge may elucidate broad parallels across animals in regard to the requirement for the co-option of bioactive compounds to ameliorate disease. Here we use biochanin A, an isoflavone found in the pollen of red clover (Trifolium pratense), to therapeutically treat Nosema bombi (Microsporidia) infection in bumblebee (Bombus terrestris) larvae and adults, and thus examine age-linked pharmacodynamics in an invertebrate. Therapeutic treatment of larvae with biochanin A did not reduce the infection intensity of N. bombi in adults. In contrast, therapeutic treatment of adults did reduce the infection intensity of N. bombi. This transition in parasite resistance to bioactive compounds mirrors the age-linked pharmacodynamics of vertebrates. Understanding how different life-history stages respond to therapeutic compounds will provide novel insights into the evolution of foraging and self-medication behaviour in natural systems more broadly
Fossils
Fossils can be completely petrified, include original material or organic matter, contain unstable mineral parts or belong to the so-called subfossils consisting mostly of original material. The latter often do not differ significantly from zoological objects and can usually be stored in the same way (see section 2.7). Completely petrified fossils are the least problematic and may be stored relatively easily under standard conditions, like simple hard rock specimens and most other stable minerals. Fossils with unstable components may require special rooms or storage conditions. Small, fragile fossils may need to be stored in closed containers, boxes, or glass vials to prevent specimens and labels from getting lost. Even in smaller fossils, the application of accession numbers directly onto the specimen can prevent misplacement if several containers or storage boxes are opened for comparative studies or for inventory purposes (see figure 2.8.4.a). Pyritised fossils are unstable Pyritised fossils, containing the iron sulphides pyrite or marcasite, are unstable and prone to decay under normal atmospheric conditions, a process known as âpyrite-mar - casite destabilisationâ or âpyrite diseaseâ (Larkin 2011). The combination of high relative humidity and atmos - pheric oxygen causes a reaction producing sulphuric acid that attacks affected specimens and which may also affect nearby drawers, labels, boxes and other neighbouring fossils. If stored in glass, affected specimens can expand and shatter their containers. Decay can be prevented if specimens are stored in an oxygen-free environment, i.e. in an inert gas compartment. For larger specimens or whole collections, however, this may not be feasible, given the costs associated with airtight storage cases or other such storage options. According to Larkin (2011), the neutralisation of sulphuric acid may be achieved through treatment with ammonium gas or ethanolamine thioglycolate. Important prevention measures include the identification and isolation of potentially affected pyritised fossils, a rel- ative humidity between 30 â 45% if possible but certainly below 60% and regular collection checks to detect the beginnings of pyrite decay, such as the presence of greyish-yellow dust smelling of sulphur. Oil shale fossils can easily fall apart Oil shale fossils can fragment if the mother rock is drying out. A short-term transfer into distilled water can save the rock from dehydration. If stored for a longer time in water (not recommended but potentially necessary in certain cases), an additive should be used to prevent the growth of mould. For mid- to long-term rescue, specimens can be stored in glycerine or permanently transferred to synthet- ic resins. In the latter technique, known as the âtransfer methodâ, the synthetic resin becomes the new support for the fossil and the original, fragile sediment is removed. To perform this transfer, different 2-component epoxy resins are available, some of which are also transparent, such as Araldite, Biresin and Bakelite/Epikote. Embedding the fossil is a permanent measure. The application of transparent or non-transparent resin should therefore be care - fully considered prior to the start of preparation, and depends on the following questions: which side should be visible at the end? Should the backside of the fossil be still visible through the resin? Shall the specimen be dis- played in the future? Will indirect lighting of the fossil through the resin be used