FINANCIAL REPORT ASSISTANCE FOR MICRO BUSINESS IN ILIR BARAT II DISTRICT, PALEMBANG CITY

Micro, Small and Medium Enterprises (MSMEs) have the potential to be developed because they contribute to the economy in Indonesia. MSMEs have a significant role in the country's economic growth The main objective of UMKM is basically to gain profits by increasing production efficiency, but in practice it often encounters many obstacles and problems, one of which is the problem of financial management. Good financial recording is very necessary because good financial recording and reporting can be used as a basis for analysis for managerial decisions that can affect business progress. The model of service activities is carried out by the method of coaching skills through the provision of materials and assistance. The result of the activity was that the participants had understood the basic material regarding financial statements, as well as provided assistance to  find out firsthand the problems faced by respondents and solutions to overcome these problems

Comparative assessment of water quality in the Dniester and Prut Rivers

Introduction. In the Republic of Moldova, the population is supplied with drinking water from surface sources, which is mainly provided from the basins of the Dniester and Prut rivers, where the water quality varies greatly. Apart from these two cross-border rivers, in accordance with Government Decision no. 890 of 12.11.2013 on the approval of the Regulation on environmental quality requirements for surface water, the National Agency for Public Health also monitors the quality of surface water from sources used for recreation and irrigation. Material and methods.379 water samples from fixed points along the Dniester and Prut rivers were investigated for sanitary-hygienic and microbiological indicators. Hygienic, statistical, descriptive and analytical methods were used within the study. Results. During 2020, in order to monitor the quality of surface water, 379 samples were taken and investigated for chemical and sanitary parameters (Dniester River – 70 samples, Prut River – 50 samples, sources used for recreation – 101 samples, sources used for irrigation – 35 samples and other sources – 123 samples) and 428 samples were assessed for microbiological parameters (Dniester River –89 samples, Prut River – 47 samples, sources used for recreation – 143 samples, sources used for irrigation – 56 samples and other sources – 56 samples).The results of the laboratory investigations of the monitored surface sources show that, depending on the sanitary-chemical indicators, the largest share of samples was related to quality class I and II (very good and good) to which the Prut water was attached (66.0%), water from irrigation sources (53.0%) and water from the Dniester River (50.0%). Furthermore, it is worth mentioning that 40.0% of samples from the Prut district were classified as being quality class IV and V (polluted and highly polluted). This share was 5.7 times higher compared to the water quality in the Dniester River, the estimated index being of 7.0%. The main indicators according to which the water was classified as polluted and highly polluted were the turbidity and the parameters of the oxygen regime, which are largely influenced by the hydrometeriological conditions. Thus, it should be concluded that the Prut River water is much more vulnerable to climatic changes compared to the Dniester River water, which has a higher self-purification capacity. Microbiological investigations of surface water quality were performed using the following parameters: total coliform bacteria, E. coli, intestinal enterococci, pathogenic microorganisms (Salmonella, Shigella, Vibrioholera), Colifagi. The results of the investigation showed a permanent pollution of the water basins with wastewater and other organic pollutants. Stable pathogenic micro-flora was detected in the water basins. In 2020, out of the total number of samples investigated for microbiological parameters, 9.0% of the pathogenic microflora was detected in the Dniester River, 8.4% - in water basins used for recreation and 3.2% in other water basins. Conclusions. There has been a sharp decline in the quality of surface water in these two rivers due to anthropogenic pollution with untreated or partially treated wastewater

Femtosecond laser microstructuring of alumina toughened zirconia for surface functionalization of dental implants

The continuous need for high-performance implants that can withstand mechanical loads while promoting implant integration into bone has focused recent research on the surface modification of hard ceramics. Their properties of biocompatibility, high mechanical and fatigue resistance and aesthetic color have contributed to its succefull applications in dentistry. Alumina toughened Zirconia (ATZ) has been gaining attention as a material for dental implants applications due to its advanced mechanical properties and minimal degradation at body temperature. Still, in order to improve tissue response to this bioinert material, additional modifications are desirable. Improving the surface functionality of this ceramic could lead to enhanced implant-tissue interaction and subsequently, a successful implant integration.In this work, microtopographies were developed on the surface of Alumina toughened Zirconia using an ultrafast laser methodology, aiming at improving the cellular response to this ceramic. Microscale grooves and grid-like geometries were produced on ATZ ceramics by femtosecond laser ablation, with a pulse width of 150 fs, wavelength of 800 nm and repetition rate of 1 kHz. The variation of surface topography, roughness, chemistry and wettability with different laser processing parameters was examined.Cell-surface interactions were evaluated for 7 days on both microstructured surfaces and a non-treated control with pre-osteoblasts, MC3T3-E1 cells. Both surface topographies showed to improve cell response, with increased metabolic activity when compared to the untreated control and modulating cell morphology up to 7 days.The obtained results suggest that femtosecond laser texturing may be a suitable non-contact methodology for creating tunable micro-scale surface topography on ATZ ceramics to enhance the biological response

Congenital brain malformations - clinic weight and expression

(Conducător ştiinţific – Svetlana Hadjiu, dr., conferenţiar universitar) Departamentul Pediatrie, Clinica neuropediatrie, USMF „Nicolae Testemiţanu”, IMSP ICŞDOSMCA congenital brain malformation frequency was assessed and their clinical manifestations in children. It was appreciated their role in the infantile neurological disability. All children included in the study underwent a complete neurological examination, were investigated neurosonographically, computed tomography (CT) - brain and magnetic resonance imaging (MRI). It was concluded that agenesis of the corpus callosum was the most common congenital brain malformation in children aged under 1 year, and most rare congenital brain malformations were anencephaly, and microgiria, hemimegalencefalia. The most common clinical manifestations in children in the study group were: neuropsychiatric retardation of varying degrees, axial and limb hypotonia, partial seizures / infantile spasms. A fost evaluată frecvenţa malformaţiilor cerebrale congenitale şi manifestările lor clinice la copii. S-a apreciat rolul acestora în invaliditatea neurologică infantilă. Toţi copiii incluşi în studiu au fost supuşi unui examen neurologic complex, au fost investigaţi paraclinic prin: examenul neurosonografic, tomografie computerizată cerebrală (TC) şi rezonanţa magnetică nucleară (RMN). S-a constatat că, agenezia corpului calos a fost cea mai frecventă malformaţie cerebrală congenitală la copiii cu vîrsta sub 1 an, iar cele mai rar întâlnite malformaţii cerebrale congenitale au fost: anencefalia, hemimegalencefalia şi microgiria. Cele mai frecvente manifestări clinice la copiii din grupul de studiu au fost: retardul neuropsihic de diferit grad, hipotonia axială şi a membrelor, crizele convulsive parţiale/spasmele infantile

Соображения, касающиеся менеджмента медицинских услуг больным сахарным диабетом

Chronic disease transformed the patient-doctor relationship into a long-term one ensuring the continuity of healthcare. The questionnaire PACIC (Patient Assessment of Chronic Illness Care) has the aim to measure the structuring of provided healthcare. We will present the Romanian version of PACIC, which is now in the phase of pre-testing and cognitive interviewing.Хроническое заболевание превратило отношение врач – пациент в долгосрочные отношения, обеспечивая непрерывность медицинской помощи. Целью анкеты PACIC (Patient Assessment of Chronic Illness Care – Оценка пациентом медицинских услуг при хроническом заболевании) является определение степени структурирования оказываемых медицинских услуг. В нашем исследовании мы представляем разработанный на румынском языке вариант, который в настоящее время находится на этапе предварительного испытания и когнитивного интервью

Richness in Functional Connectivity Depends on the Neuronal Integrity within the Posterior Cingulate Cortex

The brain's connectivity skeleton-a rich club of strongly interconnected members-was initially shown to exist in human structural networks, but recent evidence suggests a functional counterpart. This rich club typically includes key regions (or hubs) from multiple canonical networks, reducing the cost of inter-network communication. The posterior cingulate cortex (PCC), a hub node embedded within the default mode network, is known to facilitate communication between brain networks and is a key member of the "rich club." Here, we assessed how metabolic signatures of neuronal integrity and cortical thickness influence the global extent of a functional rich club as measured using the functional rich club coefficient (fRCC). Rich club estimation was performed on functional connectivity of resting state brain signals acquired at 3T in 48 healthy adult subjects. Magnetic resonance spectroscopy was measured in the same session using a point resolved spectroscopy sequence. We confirmed convergence of functional rich club with a previously established structural rich club. N-acetyl aspartate (NAA) in the PCC is significantly correlated with age (p = 0.001), while the rich club coefficient showed no effect of age (p = 0.106). In addition, we found a significant quadratic relationship between fRCC and NAA concentration in PCC (p = 0.009). Furthermore, cortical thinning in the PCC was correlated with a reduced rich club coefficient after accounting for age and NAA. In conclusion, we found that the fRCC is related to a marker of neuronal integrity in a key region of the cingulate cortex. Furthermore, cortical thinning in the same area was observed, suggesting that both cortical thinning and neuronal integrity in the hub regions influence functional integration of at a whole brain level

New Evidences on the Process Sensitivity of Some Renewable Blends Based on Starch considering Their Melt Rheological Properties

The degradability and processability of new renewable materials based on starch and PVOH were studied using the melt flow index (MFI) method by measuring the melt rheological properties which depend not only on the extrusion conditions and material formulation but also on the macromolecule characteristics which can be modified by chemical degradation. These results were correlated with other material properties like color and cross-linking degree. The obtained results show that flowing in the melted state of the studied materials is accompanied by a second process of chains chemical degradation. It was observed that, at the same level of additivation, under identical extrusion conditions, the melted blends with corn starch as main component are highly mechanically sensitive and degrade mostly by chains scission and those with PVOH as major component are highly temperature sensitive and degrade mainly by cross-linking. The obtained results show also that each PVOH-starch blend requires particular formulation and individual windows of melt processing conditions. These results are a good proof that the MFI method is a good path to study the degradability and moldability of process sensitive polymeric materials like those based on starch and PVOH

Controlling the Melt Resistance to Flow as a Possibility of Improving the Miscibility and the Time Behavior of Some Blends Based on Starch

The paper proves that the miscibility of some blends based on starch can be improved by finding for each of them the melt resistance to flow at which the nonstationary flow and the melt degradation are avoided and the developed shear rate homogenizes optimally the material composition. The obtained results show that, for process sensitive materials like starches, the border between good and less miscibility is so narrow that the window of melt processing conditions and the best formulation must be found for each of them. The improving of miscibility by controlling the melt resistance to flow proves to be a good method to prevent retrogradation and plasticizer leaching and so to handle the new compounds behavior during usage

Supplemented ERA-EDTA Registry data evaluated the frequency of dialysis, kidney transplantation, and comprehensive conservative management for patients with kidney failure in Europe

The aims of this study were to determine the frequency of dialysis and kidney transplantation and to estimate the regularity of comprehensive conservative management (CCM) for patients with kidney failure in Europe. This study uses data from the ERA-EDTA Registry. Additionally, our study included supplemental data from Armenia, Germany, Hungary, Ireland, Kosovo, Luxembourg, Malta, Moldova, Montenegro, Slovenia and additional data from Israel, Italy, Slovakia using other information sources. Through an online survey, responding nephrologists estimated the frequency of CCM (i.e. planned holistic care instead of kidney replacement therapy) in 33 countries. In 2016, the overall incidence of replacement therapy for kidney failure was 132 per million population (pmp), varying from 29 (Ukraine) to 251 pmp (Greece). On 31 December 2016, the overall prevalence of kidney replacement therapy was 985 pmp, ranging from 188 (Ukraine) to 1906 pmp (Portugal). The prevalence of peritoneal dialysis (114 pmp) and home hemodialysis (28 pmp) was highest in Cyprus and Denmark respectively. The kidney transplantation rate was nearly zero in some countries and highest in Spain (64 pmp). In 28 countries with five or more responding nephrologists, the median percentage of candidates for kidney replacement therapy who were offered CCM in 2018 varied between none (Slovakia and Slovenia) and 20% (Finland) whereas the median prevalence of CCM varied between none (Slovenia) and 15% (Hungary). Thus, the substantial differences across Europe in the frequency of kidney replacement therapy and CCM indicate the need for improvement in access to various treatment options for patients with kidney failure.Peer reviewe