462 research outputs found
Did the ancient egyptians record the period of the eclipsing binary Algol - the Raging one?
The eclipses in binary stars give precise information of orbital period
changes. Goodricke discovered the 2.867 days period in the eclipses of Algol in
the year 1783. The irregular orbital period changes of this longest known
eclipsing binary continue to puzzle astronomers. The mass transfer between the
two members of this binary should cause a long-term increase of the orbital
period, but observations over two centuries have not confirmed this effect.
Here, we present evidence indicating that the period of Algol was 2.850 days
three millenia ago. For religious reasons, the ancient Egyptians have recorded
this period into the Cairo Calendar, which describes the repetitive changes of
the Raging one. Cairo Calendar may be the oldest preserved historical document
of the discovery of a variable star.Comment: 26 pages, 5 figures, 11 table
Dynamic stereo microscopy for studying particle sedimentation
We demonstrate a new method for measuring the sedimentation
of a single colloidal bead by using a combination of optical tweezers and a stereo microscope based on a spatial light modulator. We use optical tweezers to raise a micron-sized silica bead to a ďŹxed height and then release it to observe its 3D motion while it sediments under gravity. This experimental procedure provides two independent measurements of bead diameter and a measure of FaxĂŠnâs correction, where the motion changes due to presence of the boundary
Strategic responses to global challenges: The case of European banking, 1973â2000
In applying a strategy, structure, ownership and performance (SSOP) framework to three major clearing banks (ABN AMRO, UBS, Barclays), this article debates whether the conclusions generated by Whittington and Mayer about European manufacturing industry can be applied to the financial services sector. While European integration plays a key role in determining strategy, it is clear that global factors were far more important in determining management actions, leading to significant differences in structural adaptation. The article also debates whether this has led to improved performance, given the problems experienced with both geographical dispersion and diversification, bringing into question the quality of decision-making over the long term
Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT)
Rationale:
Prospective memory (PM) deficits in recreational drug users have been documented in recent years. However, the assessment of PM has largely been restricted to self-reported measures that fail to capture the distinction between event-based and time-based PM. The aim of the present study is to address this limitation.
Objectives:
Extending our previous research, we augmented the range laboratory measures of PM by employing the CAMPROMPT test battery to investigate the impact of illicit drug use on prospective remembering in a sample of cannabis only, ecstasy/polydrug and non-users of illicit drugs, separating event and time-based PM performance. We also administered measures of executive function and retrospective memory in order to establish whether ecstasy/polydrug deficits in PM were mediated by group differences in these processes.
Results:
Ecstasy/polydrug users performed significantly worse on both event and time-based prospective memory tasks in comparison to both cannabis only and non-user groups. Furthermore, it was found that across the whole sample, better retrospective memory and executive functioning was associated with superior PM performance. Nevertheless, this association did not mediate the drug-related effects that were observed. Consistent with our previous study, recreational use of cocaine was linked to PM deficits.
Conclusions:
PM deficits have again been found among ecstasy/polydrug users, which appear to be unrelated to group differences in executive function and retrospective memory. However, the possibility that these are attributable to cocaine use cannot be excluded
Leadership and Stewardship of the Laboratory (Objective 4.1) Notable Outcome - Phase II Alternative Analysis and PNNL Site Plan Recommendation
Pacific Northwest National Laboratory (PNNL) and the Pacific Northwest Site Office (PNSO) have recently completed an effort to identify the current state of the campus and gaps that exist with regards to space needs, facilities and infrastructure. This effort has been used to establish a campus strategy to ensure PNNL is ready to further the United States (U.S.) Department of Energy (DOE) mission. Ten-year business projections and the impacts on space needs were assessed and incorporated into the long-term facility plans. In identifying/quantifying the space needs for PNNL, the following categories were addressed: Multi-purpose Programmatic (wet chemistry and imaging laboratory space), Strategic (Systems Engineering and Computation Analytics, and Collaboration space), Remediation (space to offset the loss of the Research Technology Laboratory [RTL] Complex due to decontamination and demolition), and Optimization (the exit of older and less cost-effective facilities). The findings of the space assessment indicate a need for wet chemistry space, imaging space, and strategic space needs associated with systems engineering and collaboration space. Based on the analysis, a 10-year campus strategy evolved that balanced four strategic objectives, as directed by the DOE Office of Science (DOE-SC): ⢠Mission Alignment - maintain customer satisfaction ⢠Reasonable & Achievable - do what makes sense from a practical and cost perspective ⢠Campus Continuity - increase the federal control of assets and follow the Campus Master Plan ⢠Guiding Principles - modern, collaborative, flexible, and sustainable. This strategy considered the following possible approaches to meet the identified space needs: ⢠Institutional General Plant Project (IGPP) funded projects ⢠Third party leased facilities ⢠Science Laboratory Infrastructure (SLI) line item funded projects. Pairing the four strategic objectives with additional key metrics as criteria for selection, an initial recommendation was made to DOE-SC to use all three funding mechanisms to deliver the mission need. DOE-SC provided feedback that third party facilities are not to be pursued at this time. The decision was made by DOE that an IGPP-funded program would be the base plan, while retaining the possibility of a 2019 SLI-funded project. The SLI project will be designed to deliver significant impact on science and technology (S&T) and support the development of a modern, synergistic core campus where a collaborative and innovative environment is fostered. The specific scientific impact will be further defined in the 2015 and 2016 Annual Laboratory Plans. Additionally, opportunities will be explored to construct annexes on current federal facilities, including the Environmental Molecular Sciences Laboratory (EMSL), if proven synergistic and cost effective. The final result of this effort is an actionable, flexible plan with scope, schedule, and cost targets for individual acquisition projects. Implemented as planned, the result will increase federal ownership by approximately 15 percent, reduce the operating cost by approximately 7 percent, and reduce the geographic facility footprint by approximately 66,000 gross square feet (GSF). Reduction of surplus space will be addressed while maintaining customer satisfaction, lowering operating costs, reducing the campus footprint, and increasing the federal control of assets. This strategy is documented in PNNLâs 2014 Laboratory Plan
Recruitment in the sea: bacterial genes required for inducing larval settlement in a polychaete worm
Metamorphically competent larvae of the marine tubeworm Hydroides elegans can be induced to metamorphose by biofilms of the bacterium Pseudoalteromonas luteoviolacea strain HI1. Mutational analysis was used to identify four genes that are necessary for metamorphic induction and encode functions that may be related to cell adhesion and bacterial secretion systems. No major differences in biofilm characteristics, such as biofilm cell density, thickness, biomass and EPS biomass, were seen between biofilms composed of P. luteoviolacea (HI1) and mutants lacking one of the four genes. The analysis indicates that factors other than those relating to physical characteristics of biofilms are critical to the inductive capacity of P. luteoviolacea (HI1), and that essential inductive molecular components are missing in the non-inductive deletion-mutant strains
Continuous trench, pulsed laser ablation for micro-machining applications
The generation of controlled 3D micro-features by pulsed laser ablation in various materials requires an understanding of the material's temporal and energetic response to the laser beam. The key enabler of pulsed laser ablation for micro-machining is the prediction of the removal rate of the target material, thus allowing real-life machining to be simulated mathematically. Usually, the modelling of micro-machining by pulsed laser ablation is done using a pulse-by-pulse evaluation of the surface modification, which could lead to inaccuracies when pulses overlap. To address these issues, a novel continuous evaluation of the surface modification that use trenches as a basic feature is presented in this paper. The work investigates the accuracy of this innovative continuous modelling framework for micro-machining tasks on several materials. The model is calibrated using a very limited number of trenches produced for a range of powers and feed speeds; it is then able to predict the change in topography with a size comparable to the laser beam spot that arises from essentially arbitrary toolpaths. The validity of the model has been proven by being able to predict the surface obtained from single trenches with constant feed speed, single trenches with variable feed speed and overlapped trenches with constant feed speed for three different materials (graphite, polycrystalline diamond and a metal-matrix diamond CMX850) with low error. For the three materials tested, it is found that the average error in the model prediction for a single trench at constant feed speed is lower than 5 % and for overlapped trenches the error is always lower than 10 %. This innovative modelling framework opens avenues to: (i) generate in a repeatable and predictable manner any desired workpiece microtopography; (ii) understand the pulsed laser ablation machining process, in respect of the geometry of the trench produced, therefore improving the geometry of the resulting parts; (iii) enable numerical optimisation for the beam path, thus supporting the development of accurate and flexible computer assisted machining software for pulsed laser ablation micro-machining applications
Hormonal signaling in cnidarians : do we understand the pathways well enough to know whether they are being disrupted?
Author Posting. Š The Author, 2006. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Ecotoxicology 16 (2007): 5-13, doi:10.1007/s10646-006-0121-1.Cnidarians occupy a key evolutionary position as basal metazoans and are ecologically
important as predators, prey and structure-builders. Bioregulatory molecules (e.g.,
amines, peptides and steroids) have been identified in cnidarians, but cnidarian signaling
pathways remain poorly characterized. Cnidarians, especially hydras, are regularly used
in toxicity testing, but few studies have used cnidarians in explicit testing for signal
disruption. Sublethal endpoints developed in cnidarians include budding, regeneration,
gametogenesis, mucus production and larval metamorphosis. Cnidarian genomic
databases, microarrays and other molecular tools are increasingly facilitating mechanistic
investigation of signaling pathways and signal disruption. Elucidation of cnidarian
signaling processes in a comparative context can provide insight into the evolution and
diversification of metazoan bioregulation. Characterizing signaling and signal disruption
in cnidarians may also provide unique opportunities for evaluating risk to valuable
marine resources, such as coral reefs
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