1,812 research outputs found

    Spin-orbit mode transfer via a classical analog of quantum teleportation

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    We translate the quantum teleportation protocol into a sequence of coherent operations involving three degrees of freedom of a classical laser beam. The protocol, which we demonstrate experimentally, transfers the polarisation state of the input beam to the transverse mode of the output beam. The role of quantum entanglement is played by a non-separable mode describing the path and transverse degrees of freedom. Our protocol illustrates the possibility of new optical applications based on this intriguing classical analogue of quantum entanglement.Comment: 5 pages, 7 figure

    The COVID-19 pandemic and the growing need to train engineers aligned to the sustainable development goals

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    © 2020, Emerald Publishing Limited. Purpose: Considering the requirements of sustainable development regarding professionals training and the challenges evidenced during Coronavirus disease (COVID-19) pandemic, this study aims to contribute to the debates regarding the need to insert sustainability into engineering education in the current context. Design/methodology/approach: For this, the literature about sustainability in engineering education was considered, and the need for sustainability insertion in the context of the COVID-19 pandemic was debated. It is important to emphasize that this debate was based on the authors’ experience regarding sustainability research and teaching. Findings: The current moment unveiled companies’ financial management problems, constantly evidenced by media. In this sense, the interest of engineering students in business management may lead them to believe that companies’ survival depends only on financial aspects, neglecting environmental and social aspects. This study is characterized as a reminder to academic staff in the field of engineering to continue valuing the principles of sustainable development with their students during the COVID-19 pandemic. Originality/value: The need to make engineering students understand the importance of social projects in the current period is emphasized. The training of professionals to consider all the sustainability aspects even during crisis moments is evidenced now and should be used as a learning lesson for the future

    Critical analysis of organizational change process: evidences from a steel company

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    © 2020, Emerald Publishing Limited. Purpose: The purpose of this paper is to evaluate the main factors that influence the organizational change in a steel company. Design/methodology/approach: The methodological procedures used were literature review and survey. The literature review allowed the listing of 24 factors and these factors were grouped into three constructs (Behavioral Aspects, Cultural Aspects and Management Aspects). The survey allowed the quantification of each factor based on information provided by employees who work in the mentioned company. The data collected were analyzed using the Partial Least Squares-Structural Equation Modeling technique. Findings: For the Behavioral Aspects, the following factors were validated: fear of the unknown; insecurity and anxiety; stress and feeling of suffering. For the Cultural Aspects the following factors were validated: multiculturalism in the company; low degree of risk acceptance and low performance acceptance; excessive concerns about consensus. Finally, for the Management Aspects, the following factors were validated: lack of clarity in communications; lack of alignment of goals; lack of leadership engagement. Originality/value: The results are valuable for the company studied and for other managers interested in subject. The findings presented here can broaden the debate about this topic and contribute with professionals that wish to evaluate the mentioned factors

    N170 Asymmetry as an Index of Inferior Occipital Dysfunction in Patients With Symptomatic Occipital Lobe Epilepsy

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    Objective: Localizing epileptic foci in posterior brain epilepsy remains a difficult exercise in surgery for epilepsy evaluation. Neither clinical manifestations, neurological, EEG nor neuropsychological evaluations provide strong information about the area of onset, and fast spread of paroxysms often produces mixed features of occipital, temporal and parietal symptoms. We investigated the usefulness of the N170 event-related potential to map epileptic activity in these patients. Methods: A group of seven patients with symptomatic posterior cortex epilepsy were submitted to a high-resolution EEG (78 electrodes), with recordings of interictal spikes and face-evoked N170. Generators of spikes and N170 were localized by source analysis. Range of normal N170 asymmetry was determined in 30 healthy volunteers. Results: In 3 out of 7 patients the N170 inter-hemispheric asymmetry was outside control values. Those were the patients whose spike sources were nearest (within 3 cm) to the fusiform gyrus, while foci further away did not affect the N170 ratio. Conclusions: N170 event-related potential provides useful information about focal cortical dysfunction produced by epileptic foci located in the close neighborhood of the fusiform gyrus, but are unaffected by foci further away. Significance: The N170 evoked by faces can improve the epileptic foci localization in posterior brain epilepsy

    Eficacia y seguridad del adhesivo tisular Tisuacryl en el cierre de la piel de la episiotomĂ­a

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    Se realizĂł un ensayo clĂ­nico fase III, en el Hospital Docente Materno Infantil 10 de Octubre, de Ciudad de La Habana, Cuba, entre julio de 1999 y marzo del 2000, con el objetivo de evaluar la eficacia y seguridad del adhesivo tisular Tisuacryl en el cierre de la piel de la episiotomĂ­a. Cada grupo constĂł de 300 pacientes, de acuerdo a los criterios de inclusiĂłn establecidos para el ensayo. En el grupo estudio se presentaron menos molestias en la episiorrafia (95.6 %) que en el grupo control (56.3 %) a los 30 minutos post parto, asĂ­ como al tercer dĂ­a posterior al nacimiento (97.6 % vs. 61.3 %). Al sĂ©ptimo dĂ­a, los resultados en el afrontamiento, estĂ©tica y molestias en la herida fueron significativamente mejores con el adhesivo tisular evaluado. Los riesgos relativos de resultados adversos al sĂ©ptimo dĂ­a posterior al parto fueron 3.2 veces mayores en relaciĂłn con afrontamiento y 2.9 veces con la estĂ©tica no satisfactorias cuando se utilizĂł catgut cromado al comparar con el Tisuacryl. Para las molestias en la episiorrafia, el riesgo relativo se elevĂł a 24.2, todos con diferencias estadĂ­sticas significativas. Se concluye que el uso del adhesivo tisular Tisuacryl para el cierre de la piel en la episiotomĂ­a tiene menor probabilidad de afrontamiento y estĂ©tica de la herida no satisfactoria y de menor sensaciĂłn dolorosa en la herida quirĂșrgica que el catgut cromado.Peer Reviewe

    Superpulsed low-level laser therapy protects skeletal muscle of mdx mice against damage, inflammation and morphological changes delaying dystrophy progression.

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    Aim: To evaluate the effects of preventive treatment with low-level laser therapy (LLLT) on progression of dystrophy in mdx mice. Methods: Ten animals were randomly divided into 2 experimental groups treated with superpulsed LLLT (904 nm, 15 mW, 700 Hz, 1 J) or placebo-LLLT at one point overlying the tibialis anterior muscle (bilaterally) 5 times per week for 14 weeks (from 6th to 20th week of age). Morphological changes, creatine kinase (CK) activity and mRNA gene expression were assessed in animals at 20th week of age. Results: Animals treated with LLLT showed very few morphological changes in skeletal muscle, with less atrophy and fibrosis than animals treated with placebo-LLLT. CK was significantly lower (p = 0.0203) in animals treated with LLLT (864.70 U.l−1, SEM 226.10) than placebo (1708.00 U.l−1, SEM 184.60). mRNA gene expression of inflammatory markers was significantly decreased by treatment with LLLT (p<0.05): TNF-α (placebo-control = 0.51 ”g/”l [SEM 0.12], - LLLT = 0.048 ”g/”l [SEM 0.01]), IL-1ÎČ (placebo-control = 2.292 ”g/”l [SEM 0.74], - LLLT = 0.12 ”g/”l [SEM 0.03]), IL-6 (placebo-control = 3.946 ”g/”l [SEM 0.98], - LLLT = 0.854 ”g/”l [SEM 0.33]), IL-10 (placebo-control = 1.116 ”g/”l [SEM 0.22], - LLLT = 0.352 ”g/”l [SEM 0.15]), and COX-2 (placebo-control = 4.984 ”g/”l [SEM 1.18], LLLT = 1.470 ”g/”l [SEM 0.73]). Conclusion: Irradiation of superpulsed LLLT on successive days five times per week for 14 weeks decreased morphological changes, skeletal muscle damage and inflammation in mdx mice. This indicates that LLLT has potential to decrease progression of Duchenne muscular dystrophy

    Prognostic Implications of Tissue Doppler in Patients with Dilated Cardiomyopathy

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    Previous studies have shown that a ratio of early transmitral flow velocity to early diastolic velocity of the mitral annulus (E/E') of > 15, obtained by tissue Doppler imaging (TDI), correlates with left ventricular filling pressure. OBJECTIVE: The aim of our study was to assess whether E/E' provides prognostic information in patients with dilated cardiomyopathy. METHODS: We studied 33 patients with dilated cardiomyopathy and mean ejection fraction of 31%. All the patients underwent routine two-dimensional and Doppler echocardiographic examination and TDI to determine early peak velocity of the mitral annulus. Pro-B-type natriuretic peptide (pro-BNP) and peak oxygen consumption (VO2max) were also measured. Patients were divided into two groups according to the value of E/E': Group I (n = 15 patients) with E/E' > or = 15 and Group II (n = 18 patients) with E/E' < 15. Patients were followed for 12+/-4 months; new hospital admission due to heart failure, heart transplantation and death were considered as cardiac events. RESULTS: There were significant differences between the two groups in conventional two-dimensional echocardiographic measurements (dimensions and ejection fraction) and Doppler parameters (mitral inflow). With regard to mitral annular velocities obtained by TDI at two different points (septum and lateral wall), the E', A' and S' velocities differed significantly between the two groups, with lower velocities in Group I. Systolic velocity measured in the lateral portion of the mitral annulus showed the most significant difference: Group I - 4.46 cm/sec versus Group II - 7.19 cm/sec, p < 0.00001. Pro-BNP was 5622 pg/ml in Group I, and 1254 pg/ml in Group II, p = 0.004. VO2 max was significantly different between the two groups: Group I - 17.6 ml/kg/min versus Group II - 22.8 ml/kg/min, p = 0.004. During follow-up, events were more common in Group I, with 9 patients (60%) having events, while in Group II, the event rate was 11.1% (2 patients), p = 0.004. CONCLUSION: The ratio of early transmitral flow velocity to early diastolic velocity of the mitral annulus is a powerful predictor of clinical outcome. Lower velocities of mitral annulus on TDI are expected in patients with E/E' > or = 15. Systolic velocities of under 5 cm/sec measured in the lateral portion of the mitral annulus appeared to be strongly related to prognosis

    Lung cancer samples preserved in liquid medium: One step beyond cytology

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    Lung cancer is one of the most common cancer types in men and women worldwide with a high mortality rate. World Health Organization (WHO) classification has accepted biopsy as the primary sample for lung cancer diagnosis, pathological classification and molecular testing for management of patients, yet, the use of alternative sampling procedures is highly encouraged. Bronchial cytological samples require a less invasive collection technique and may be suitable for pathological and molecular analysis and storage in liquid medium. Furthermore, the molecular analysis of bronchial cytological samples allows the detection of molecular biomarkers, which may be useful for the selection of molecular targeted therapies. Thus, the purpose of this review is to describe the usefulness of bronchial cytological samples preserved in liquid medium from lung cancer patients for pathological diagnosis and molecular investigation.Rui Manuel Reis and Adhemar Longatto-Filho have a Brazilian National Counsel of Technological and Scientific Development (CNPq) Produtivity scholarship.info:eu-repo/semantics/publishedVersio
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