E. Leal

J. Feliciano

José Luís Pais Ribeiro

M. Oliveira

N. da Silva

R. Ferreira

R. Soares

S. Alves

S. Santos

Open Repository of the University of Porto

p=.008), more LBBB by ECG (85% vs. 62%, p=.009) and
less restrictive filling pattern by Doppler echocardiography
(23% vs. 50%, p=.030) when compared with ND. Pts with
intraVD compared with ND had a tendency towards
increased baseline QRS width (163 plus minus 31 vs. 153
plus minus 25, p=.107) and lower incidence of deterioration
following CRT (7.4% vs. 23.5%, p=.066). Both interVD
and intraVD improved with treatment. Neither interVD nor
intraVD predicted clinical or echocardiographic response to
CRT when compared to ND.
Conclusion InterVD but not intraVD is associated with a
significant increased baseline QRS width, LBBB and
restrictive filling pattern. Neither interVD nor intraVD were
predictors of clinical or echocardiographic response to CRT.
22–3 Abstract 24–03
Health related quality of life in patients with congestive
refractory heart failure after cardiac resynchronization
therapy—a six month follow-up study
Elisabete Nave Leal1, José Pais Ribeiro2, Mário Oliveira3,
Manuel Nogueira da Silva3, Joana Feliciano3, Rui Soares3,
Sofia Santos3, Sandra Alves3, Rui Ferreira3
1Faculdade de Psicologia e Ciências da Educação, UP;
Escola Superior de Tecnologia da Saúde de Lisboa, IPL,
Oporto; Lisbon, Portugal
2Faculdade de Psicologia e Ciências da Educação, UP,
Oporto, Portugal
3Centro Hospitalar de Lisboa Central, Hospital de Santa
Marta, Lisbon, Portugal
Aim of the study To evaluate the impact of cardiac
resynchronization therapy (CRT) in the quality of life
(QOL) of patients (P) with congestive heart failure (CHF)
refractory to optimal pharmacologic therapy, at the 6th
month of follow-up.
Population and Methods 41P with CHF (28 men and 13
women, 63.9±9.1 years) in Class II–IV of NYHA (95%
class III), with poor left ventricular ejection fraction (LVEF)
(24±3%). The diagnosis was ischemic heart disease in
24.4%, idiopathic dilated cardiomyopathy in 58.5%, hyper-
tensive heart disease in 9.8% and valvular heart disease in
7.3%. The clinical history was of 10.2±8.0 years for
the heart disease and at least one hospitalization due to
CHF. All P received devices with combined CRT and
cardioverter–defibrillator (CRT-D). They were evaluated in
the hospital, just before the intervention, and in the
outpatient clinic within 6 months, regarding the NYHA
functional class, LVEF and the QOL Kansas City Cardio-
miophathy Questionnaire (KCCQ), as validated for the
Portuguese population.
Results After CRT-D 73.2% of the P were in NYHA class
II, with LVEF of 36±8% and an overall average score of
QOL which increased from 53±24 to 83±21 (ρ<0.05).
Specifically, as seen in the various fields, KCCQ have the
following developments: the average score of activities of
daily living increased from 53±25 to 87±19; of symptoms
increased from 56±26 to 81±23; the perception of
satisfaction with life increased from 38±29 to 78±27; the
lifestyle increased from 58±30 to 85±26, and the function-
ality increased from 56±24 to 85±20. In the score of
knowledge the average value for the clinical condition did
not change significantly.
Conclusion In P with severe CHF, CRT has a favorable
impact on QOL, in the improvement of left ventricular
function and functional class.
22–4 Abstract 24–05
Repetitive electrical cardioversions and cardiac
resynchronization therapy in heart failure patients
with atrial fibrillation: the SIBILLA study
Pietro Turco1, Francesco Solimene2, Giuseppe Stabile3,
Antonio De Simone3, Antonio D'Onofrio4
1Electrophysiology Laboratory, Hesperia Hospital Modena,
Modena, Italy
2Electrophysilogy Laboratory, Clinica Montevergine,
Mercogliano Avellino, Italy
3Electrophysiology Laboratory, Clinica San Michele,
Maddaloni Caserta, Italy
4Electrophysiology Laboratory, Ospedale Monaldi, Napoli,
Italy
Background Permanent and persistent atrial fibrillation (AF)
is a common supraventricular arrhythmia in heart failure (HF)
patients. The AF incidence is related to the severity of clinical
condition and could reach the 50% in NYHA IV functional
class patients. AF is associated with an increased risk of
mortality, hospitalization and HF progression in patients with
left ventricular systolic dysfunction. Cardiac resynchronisa-
tion therapy (CRT) can be beneficial in HF patients with
concomitant AF in terms of improved symptoms, exercise
capacity, systolic left ventricular function and mortality.
However very few data have reported a direct influence of
CRT in restoring sinus rhythm (SR) and spontaneous
reversion from AF to SR is a rare and unclear event.
Aim of the study Electrical cardioversion (EC), performed
immediately or after few months the implantation of a CRT
292 J Interv Card Electrophysiol (2009) 24:291–297


English

Health related quality of life in patients with congestive refractory heart failure after cardiac resynchronization therapy: a six month follow-up study

Repositório Aberto da Universidade do Porto

p=.008), more LBBB by ECG (85% vs. 62%, p=.009) andless restrictive filling pattern by Doppler echocardiography(23% vs. 50%, p=.030) when compared with ND. Pts withintraVD compared with ND had a tendency towardsincreased baseline QRS width (163 plus minus 31 vs. 153plus minus 25, p=.107) and lower incidence of deteriorationfollowing CRT (7.4% vs. 23.5%, p=.066). Both interVDand intraVD improved with treatment. Neither interVD norintraVD predicted clinical or echocardiographic response toCRT when compared to ND.Conclusion InterVD but not intraVD is associated with asignificant increased baseline QRS width, LBBB andrestrictive filling pattern. Neither interVD nor intraVD werepredictors of clinical or echocardiographic response to CRT.22–3 Abstract 24–03Health related quality of life in patients with congestiverefractory heart failure after cardiac resynchronizationtherapy—a six month follow-up studyElisabete Nave Leal1, José Pais Ribeiro2, Mário Oliveira3,Manuel Nogueira da Silva3, Joana Feliciano3, Rui Soares3,Sofia Santos3, Sandra Alves3, Rui Ferreira31Faculdade de Psicologia e Ciências da Educação, UP;Escola Superior de Tecnologia da Saúde de Lisboa, IPL,Oporto; Lisbon, Portugal2Faculdade de Psicologia e Ciências da Educação, UP,Oporto, Portugal3Centro Hospitalar de Lisboa Central, Hospital de SantaMarta, Lisbon, PortugalAim of the study To evaluate the impact of cardiacresynchronization therapy (CRT) in the quality of life(QOL) of patients (P) with congestive heart failure (CHF)refractory to optimal pharmacologic therapy, at the 6thmonth of follow-up.Population and Methods 41P with CHF (28 men and 13women, 63.9±9.1 years) in Class II–IV of NYHA (95%class III), with poor left ventricular ejection fraction (LVEF)(24±3%). The diagnosis was ischemic heart disease in24.4%, idiopathic dilated cardiomyopathy in 58.5%, hyper-tensive heart disease in 9.8% and valvular heart disease in7.3%. The clinical history was of 10.2±8.0 years forthe heart disease and at least one hospitalization due toCHF. All P received devices with combined CRT andcardioverter–defibrillator (CRT-D). They were evaluated inthe hospital, just before the intervention, and in theoutpatient clinic within 6 months, regarding the NYHAfunctional class, LVEF and the QOL Kansas City Cardio-miophathy Questionnaire (KCCQ), as validated for thePortuguese population.Results After CRT-D 73.2% of the P were in NYHA classII, with LVEF of 36±8% and an overall average score ofQOL which increased from 53±24 to 83±21 (ρ<0.05).Specifically, as seen in the various fields, KCCQ have thefollowing developments: the average score of activities ofdaily living increased from 53±25 to 87±19; of symptomsincreased from 56±26 to 81±23; the perception ofsatisfaction with life increased from 38±29 to 78±27; thelifestyle increased from 58±30 to 85±26, and the function-ality increased from 56±24 to 85±20. In the score ofknowledge the average value for the clinical condition didnot change significantly.Conclusion In P with severe CHF, CRT has a favorableimpact on QOL, in the improvement of left ventricularfunction and functional class.22–4 Abstract 24–05Repetitive electrical cardioversions and cardiacresynchronization therapy in heart failure patientswith atrial fibrillation: the SIBILLA studyPietro Turco1, Francesco Solimene2, Giuseppe Stabile3,Antonio De Simone3, Antonio D'Onofrio41Electrophysiology Laboratory, Hesperia Hospital Modena,Modena, Italy2Electrophysilogy Laboratory, Clinica Montevergine,Mercogliano Avellino, Italy3Electrophysiology Laboratory, Clinica San Michele,Maddaloni Caserta, Italy4Electrophysiology Laboratory, Ospedale Monaldi, Napoli,ItalyBackground Permanent and persistent atrial fibrillation (AF)is a common supraventricular arrhythmia in heart failure (HF)patients. The AF incidence is related to the severity of clinicalcondition and could reach the 50% in NYHA IV functionalclass patients. AF is associated with an increased risk ofmortality, hospitalization and HF progression in patients withleft ventricular systolic dysfunction. Cardiac resynchronisa-tion therapy (CRT) can be beneficial in HF patients withconcomitant AF in terms of improved symptoms, exercisecapacity, systolic left ventricular function and mortality.However very few data have reported a direct influence ofCRT in restoring sinus rhythm (SR) and spontaneousreversion from AF to SR is a rare and unclear event.Aim of the study Electrical cardioversion (EC), performedimmediately or after few months the implantation of a CRT292 J Interv Card Electrophysiol (2009) 24:291–297

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Health related quality of life in patients with congestive refractory heart failure after cardiac resynchronization therapy: a six month follow-up study

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